Doniphan Vacations from $784

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The Latest Doniphan vacation packages

Price found within the past 48 hours. Click for updated prices.
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

3 out of 5
Price was $851, price is now $784 per person
$784
per person
Aug 6 - Aug 9
found 12 hours ago
Roundtrip non-stop flight included
Raleigh (RDU) to Cape Girardeau (CGI)
9.6/10 Exceptional! (95 reviews)
It was a very neat experience! Highly recommend you stop here and get away from big chain hotels for a night. The staff were super friendly and the restaurant/store was so nostalgic!

Reviewed on Jun 7, 2026

Rockwood Inn

Rockwood Inn

2 out of 5
Price was $958, price is now $882 per person
$882
per person
Aug 6 - Aug 9
found 12 hours ago
Roundtrip non-stop flight included
Raleigh (RDU) to Cape Girardeau (CGI)
10/10 Exceptional! (20 reviews)
My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning!

Reviewed on Dec 28, 2025

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
Price was $913, price is now $875 per person
$875
per person
Aug 6 - Aug 9
found 12 hours ago
Roundtrip non-stop flight included
Raleigh (RDU) to Cape Girardeau (CGI)
9.4/10 Exceptional! (1,004 reviews)
I will definitely be staying here next time I visit SEMO.

Reviewed on Jun 5, 2026

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
Price was $1,131, price is now $1,087 per person
$1,087
per person
Aug 27 - Aug 31
found 1 day ago
Roundtrip flight included
Oakland (OAK) to Cape Girardeau (CGI)
9.6/10 Exceptional! (1,006 reviews)
Very clean, helpful staff

Reviewed on Jun 2, 2026

Makanda Inn

Makanda Inn

3.5 out of 5
Price was $1,284, price is now $1,243 per person
$1,243
per person
Aug 27 - Aug 31
found 1 day ago
Roundtrip flight included
Oakland (OAK) to Cape Girardeau (CGI)
10/10 Exceptional! (37 reviews)
Jackie was amazing. She was very informative and helpful. Great communication. The room was really comfortable. And breakfast was great.

Reviewed on May 10, 2026

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Doniphan Hotel Deals

Rustic Lodge Near Current River: Pond + Fire pit + Trails + Pickleball + Fishing

Rustic Lodge Near Current River: Pond + Fire pit + Trails + Pickleball + Fishing

Grandin MO
$690 nightly
The price is $728 total per night from Jun 10 to Jun 11
$728 total
Jun 10 - Jun 11
Total with taxes and fees
10/10 Exceptional! (19 reviews)
"There’s something special about getting away to a place where time slows down a little. We stayed at a beautiful lodge tucked away on several peaceful acres with a stocked pond perfect for fishing, and it was honestly the reset we didn’t know we needed. The amenities were second to none, the atmosphere ..."

Reviewed on May 24, 2026

Rustic Lodge Near Current River: Pond + Fire pit + Trails + Pickleball + Fishing
Cabin Right on Current River, conveniently located close to town.

Cabin Right on Current River, conveniently located close to town.

Doniphan MO
9.6/10 Exceptional! (42 reviews)
"We got what we came for: A lovely and somewhat remote retreat looking(literally) over the Current River with a deck and a fire pit with comfortable beds, hot water, and enough kitchen gear to prepare meals. You can even do some light fishing from the old boat ramp but more to pass the time than get ..."

Reviewed on May 12, 2026

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Cabin Right on Current River, conveniently located close to town.
Romantic couples retreat 100 feet from Current River, Doniphan, MO

Romantic couples retreat 100 feet from Current River, Doniphan, MO

Doniphan MO
10/10 Exceptional! (16 reviews)
"This place was perfect! It had everything you could want from snack basket, coffee, firewood and smores ingredients, all the way down to spare tooth brushes. The cabin is beautiful and the location was absolutely gorgeous! The host was quick to respond to messages, answered any question we had and ..."

Reviewed on Apr 19, 2026

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Romantic couples retreat 100 feet from Current River, Doniphan, MO
See all 153 properties in Doniphan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Doniphan Vacation Packages

Doniphan Essential Information

Language
English
Currency
U.S dollars
Population
2,000
Max Temp Winter
45ºF
Max Temp Summer
90ºF

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Frequently asked questions

How much does a Doniphan vacation package cost?
You'll find cheap prices from $784 on Expedia for your Doniphan escape. However, a range of factors like your choice of hotel, the season and length of stay will determine how much your vacation to Doniphan costs.
What are the cheapest months to go to Doniphan?
February, November and December are the best times to look for cheap Doniphan vacation packages. Opting to travel in quieter months means you can typically find lower prices on flights and hotels.
How many days is enough for Doniphan?
The ideal duration of your Doniphan vacation depends on what you'd like to see. Typically, a few days to a week will give you enough time to hit all the top attractions and explore some hidden gems along the way.
How to find the best Doniphan package deals?
Begin your search for a Doniphan package deal by entering your destination and preferred travel dates under our "Packages" tab. Then add a few filters, like "Property type" and "Popular locations," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with big savings. If you don't find the perfect Doniphan package deal straight away, simply play around with your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Doniphan getaway off to a flying start.
Is it cheaper to book a Doniphan vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, hotel and flight into one great-value price and you could save hundreds of dollars. You'll generally score a better deal than booking each component individually. And you'll still get the flexibility to create a personalized Doniphan vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to Doniphan?
If you're considering an impromptu Doniphan vacation, check out our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can find incredible deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Doniphan vacation packages?
Jet off on your dream trip to Doniphan with Expedia's Book Now, Pay Later vacations. There's no need to save up or hold off until payday — we've teamed up with online lender Affirm to give you flexibility with your finances. Our vacation packages with payment plans let you spread the cost over 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to budget for your trip and snap up bargains before they disappear.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.