Doniphan Vacations from $451

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The Latest Doniphan vacation packages

Price found within the past 48 hours. Click for updated prices.
Quality Inn

Quality Inn

2.5 out of 5
Price was $458, price is now $451 per person
$451
per person
May 9 - May 11
found 16 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Cape Girardeau (CGI)
7.2/10 Good! (674 reviews)
The room was clean and nice. The breakfast was really good.

Reviewed on Dec 28, 2025

The Riverview

The Riverview

4 out of 5
Price was $547, price is now $529 per person
$529
per person
May 9 - May 11
found 16 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Cape Girardeau (CGI)
9.4/10 Exceptional! (452 reviews)
The room was perfect for the evening and occasion!

Reviewed on Feb 21, 2026

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
Price was $519, price is now $508 per person
$508
per person
May 9 - May 11
found 16 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Cape Girardeau (CGI)
9.4/10 Exceptional! (1,001 reviews)
Would have been a 5 rating except for the noisy heating system.

Reviewed on Feb 2, 2026

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
Price was $494, price is now $485 per person
$485
per person
May 9 - May 11
found 16 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Cape Girardeau (CGI)
8/10 Very Good! (871 reviews)
Staff was great, bed was amazing, but had to leave a cup over the kitchen sink drain due to roaches.

Reviewed on Jan 7, 2026

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
Price was $529, price is now $522 per person
$522
per person
May 9 - May 11
found 16 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Cape Girardeau (CGI)
9.6/10 Exceptional! (1,003 reviews)
They were very nice people and very considerate to my situation. I would stay there anytime and recommend to everyone

Reviewed on Feb 20, 2026

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Doniphan Hotel Deals

Rustic Lodge for 14 near Current River on private 35 acres

Rustic Lodge for 14 near Current River on private 35 acres

Grandin MO
$690 nightly
The price is $714 total per night from Feb 23 to Feb 24
$714 total
Feb 23 - Feb 24
Total with taxes and fees
Rustic Lodge for 14 near Current River on private 35 acres
"Firefly on the Current" Gorgeous Riverfront Modern Cabin on Current River

"Firefly on the Current" Gorgeous Riverfront Modern Cabin on Current River

Doniphan MO
9.8/10 Exceptional! (18 reviews)
Easy to check in Lovw the open kitchen concept Wifi was kinda lagging but when it worked it worked wellAlso, who's there for the internetAnd TV anyway, we were there for the water!!Easy access to everything Can't wait to come to the area again.

Reviewed on Aug 17, 2025

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"Firefly on the Current" Gorgeous Riverfront Modern Cabin on Current River
Romantic couples retreat 100 feet from Current River, Doniphan, MO

Romantic couples retreat 100 feet from Current River, Doniphan, MO

Doniphan MO
10/10 Exceptional! (12 reviews)
This place is wonderful!! It’s a cozy comfortable cabin that is well maintained and the perfect spot for a couple’s get away. There is plenty of indoor and outdoor seating to take advantage of the beautiful views of the river. It’s secluded and private yet only 10 or 15 minutes away from a quint ...

Reviewed on Feb 15, 2026

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Romantic couples retreat 100 feet from Current River, Doniphan, MO
See all 142 properties in Doniphan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Doniphan Vacation Packages

Doniphan Essential Information

Language
English
Currency
U.S dollars
Population
2,000
Max Temp Winter
45ºF
Max Temp Summer
90ºF

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Frequently asked questions

How much does a Doniphan vacation package cost?
You'll find cheap prices from $451 on Expedia for your Doniphan escape. However, a range of factors like your choice of hotel, the season and length of stay will determine how much your vacation to Doniphan costs.
What are the cheapest months to go to Doniphan?
February, November and December are the best times to look for cheap Doniphan vacation packages. Opting to travel in quieter months means you can typically find lower prices on flights and hotels.
How many days is enough for Doniphan?
The ideal duration of your Doniphan vacation depends on what you'd like to see. Typically, a few days to a week will give you enough time to hit all the top attractions and explore some hidden gems along the way.
How to find the best Doniphan package deals?
Begin your search for a Doniphan package deal by entering your destination and preferred travel dates under our "Packages" tab. Then add a few filters, like "Property type" and "Popular locations," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with big savings. If you don't find the perfect Doniphan package deal straight away, simply play around with your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Doniphan getaway off to a flying start.
Is it cheaper to book a Doniphan vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, hotel and flight into one great-value price and you could save hundreds of dollars. You'll generally score a better deal than booking each component individually. And you'll still get the flexibility to create a personalized Doniphan vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to Doniphan?
If you're considering an impromptu Doniphan vacation, check out our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can find incredible deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Doniphan vacation packages?
Jet off on your dream trip to Doniphan with Expedia's Book Now, Pay Later vacations. There's no need to save up or hold off until payday — we've teamed up with online lender Affirm to give you flexibility with your finances. Our vacation packages with payment plans let you spread the cost over 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to budget for your trip and snap up bargains before they disappear.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.