Downtown Guayaquil Vacations from $242

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Your Downtown Guayaquil Vacation

From its views to its culture and history, there are loads of tempting reasons to book a vacation package to Downtown Guayaquil. When you want to escape the everyday, this lively neighborhood has a spot just for you. Want to see the sights during your trip to Downtown Guayaquil? Pencil in a visit to nearby attractions such as Malecon 2000, Banco Pichincha Monumental Stadium and Mall del Sol Commercial Center. Whatever your travel goals or the size of your budget, booking your ideal Downtown Guayaquil vacation is simple with Expedia.

The Latest Downtown Guayaquil Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Mansión Alcázar Boutique Hotel

Mansión Alcázar Boutique Hotel

Downtown Cuenca
$242
per person
Nov 24 - Nov 26
found 1 day ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
9.6/10 Exceptional! (390 reviews)
Great hotel and service

Reviewed on Oct 24, 2026

Hotel Cruz del Vado by Art Hotels Ecuador

Hotel Cruz del Vado by Art Hotels Ecuador

Save 100% on your flight
$266
per person
Jan 6 - Jan 8
found 19 hours ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
9.4/10 Exceptional! (45 reviews)
Everything was great. Unfortunately I didn’t check but most of the rooms are windowless. As I’m claustrophobic this was issue. The other thing if you are coming by car is the parking which is about half a block away. These are common themes for hotels in the historic center though. If you are looking for traditional American comfort try hotels on the other side of town

Reviewed on Oct 11, 2026

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

Las Peñas
$1,133
per person
Dec 11 - Dec 14
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Guayaquil (GYE)
10/10 Exceptional! (5 reviews)
Hotel Boutique Santa Lucia

Hotel Boutique Santa Lucia

Downtown Cuenca
$248
per person
Nov 24 - Nov 26
found 1 day ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
9.2/10 Wonderful! (409 reviews)
Hotel Ramada

Hotel Ramada

Downtown Guayaquil
$813
per person
Nov 24 - Nov 30
found 19 hours ago
Roundtrip flight included
New York (NYC) to Guayaquil (GYE)
8/10 Very Good! (418 reviews)
Como siempre me atienden super bien

Reviewed on Oct 9, 2026

Where to stay in Downtown Guayaquil

Find the best Downtown Guayaquil areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Guayaquil
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Numa Pompilio Llona Street while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

1 out of top 10 points of interest in this area

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

A cityscape with a prominent skyscraper, a river, and a bridge.

Simón Bolívar

1 out of top 10 points of interest in this area

Simón Bolívar might not have many top sights, but Mall del Sol Shopping Center and San Marino Mall are two attractions nearby that you can check out.

A coastal cityscape at dusk with a prominent Ferris wheel, high-rise buildings, and a busy street.

Garzota

The restaurants and shopping are a few reasons travelers visit Garzota. Though there aren't many top sights in the neighborhood, you can visit Mall del Sol Shopping Center and City Mall, a few notable attractions nearby.

Downtown Guayaquil Hotel Deals

Oro Verde Guayaquil

Oro Verde Guayaquil

9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$85 nightly
$96 total
Nov 13 - Nov 14
9.6/10 Exceptional! (1,004 reviews)
"This is a very good hotel that I would highly recommend and I’m not a person that recommend something if it didn’t match up to its reviews and it certainly did that"

Reviewed on Oct 23, 2026

Oro Verde Guayaquil
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

Clemente Ballén 406 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$63 nightly
$73 total
Nov 24 - Nov 25
9.2/10 Wonderful! (1,000 reviews)
"Excelente ubicación y la amabilidad del personal"

Reviewed on Oct 21, 2026

Unipark by Oro Verde Hotels
Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.

Boyaca 1615 Guayaquil Guayas
Fully refundable
$79 nightly
$89 total
Nov 15 - Nov 16
Grand Hotel Guayaquil, Centro Histórico.
See all 443 properties in Downtown Guayaquil
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Downtown Guayaquil attractions

A gazebo, a large tree, and a cathedral in the background.
Photo by Tahino2000

Guayaquil Metropolitan Cathedral

9.0/10 (113 reviews)
After visiting Guayaquil Metropolitan Cathedral, make a plan to see the other sights and activities in Guayaquil. While you're in the area, find time to visit its shops.
See properties
An iguana on green grass.
Photo by Botak Jon

Seminario Park

After visiting Seminario Park, make a plan to see the other sights and activities in Guayaquil. While you're in the area, find time to visit its shops.
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Sports Federation of Guayas

7.4/10 (3 reviews)
Catch an event at Sports Federation of Guayas during your trip to Guayaquil. While you're in the area, find time to visit its shops.
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Moorish Clock Tower

8.0/10 (1 review)
You can learn about the history of Guayaquil with a stop at Moorish Clock Tower. While you're in the area, find time to visit its shops.
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Central Market

8.0/10 (19 reviews)
During your trip to Guayaquil, you can find the perfect gifts to bring home at Central Market. While in this family-friendly area, you can savor the top-notch restaurants.
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Centennial Park

9.0/10 (49 reviews)
Centennial Park is just one of the places to see in Guayaquil, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.
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La Rotonda

Learn about the local history of Guayaquil with a stop at La Rotonda. While you're in the area, find time to visit its shops.
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Artisan Market

7.4/10 (3 reviews)
During your visit to Guayaquil, you can browse for the perfect souvenirs at Artisan Market. While in this family-friendly area, you can savor the top-notch restaurants.
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Things to do

City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

$65
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

$122
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
Cocoa farm and Chocolate making!

Cocoa farm and Chocolate making!

$155
per adult
Cocoa farm and Chocolate making!
See all activities in Guayaquil

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