Puerto Santa Ana Vacations from $530
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Your Puerto Santa Ana Vacation
With plenty of highlights as well as some hidden gems, this city is best experienced with a Puerto Santa Ana vacation package. Find somewhere to stay in Downtown Guayaquil, which is good for views, culture and history. Malecon 2000, Banco Pichincha Monumental Stadium and Mall del Sol Commercial Center are just a few of the many attractions you'll want to see during your trip to Puerto Santa Ana. Whoever you're taking time off with and whatever you plan to spend, your ultimate Puerto Santa Ana vacation is just a few clicks away with Expedia.
The Latest Puerto Santa Ana Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Air Suites
Simón Bolívar
per person
Oct 1 - Oct 8
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
6.6/10 (199 reviews)
When you get to the Equator you will be greeted by cockroaches at some point. Sadly there was a small one on one of the beds. Otherwise, the place was clean and the breakfast was fantastic. For the price, I was happy.
Reviewed on May 27, 2023
Hotel Rio Guayas
Las Peñas
per person
Oct 1 - Oct 8
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
No reviews
I absolutely loved my stay at Hotel Rio Guayas! The staff was incredibly kind, attentive, and made me feel truly welcome. One of the highlights was the stunning river view from the restaurant absolutely unforgettable. The hotel feels luxurious, with beautiful artwork and elegant decor throughout. Everything was spotless and comfortable. I highly recommend this place and would love to stay again! For Sureeee
Reviewed on Jul 30, 2025
Luxury Suites Riverfront GYE
Puerto Santa Ana
per person
Oct 1 - Oct 8
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
9.4/10 Exceptional! (91 reviews)
The property is close to the Malecon and airport. The shades and windows were dirty. It looked a bit drab inside.
Reviewed on May 15, 2025
Oro Verde Guayaquil
Downtown Guayaquil
per person
Oct 1 - Oct 8
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
9.4/10 Exceptional! (1,000 reviews)
I love that they are changing walls and fixtures also that the smelling in the entrance is better and now looks more organized in general
Reviewed on Jul 29, 2025
Where to stay in Puerto Santa Ana
Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Puerto Santa Ana
Downtown Guayaquil
Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.
Puerto Santa Ana Hotel Deals
Wyndham Guayaquil Puerto Santa Ana
Calle Numa Pompilio Llona S N, Ciudad del Rio - Puerto Santa Ana, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $124 total per night from Aug 11 to Aug 12
$124 total
Aug 11 - Aug 12
9.2/10 Wonderful! (1,007 reviews)
"The best hotel in guyaquil"
Reviewed on Jul 28, 2025
Luxury Suites Riverfront GYE
Puerto Santa Ana, Guayaquil, Guayas
$90 nightly
The price is $91 total per night from Jul 31 to Aug 1
$91 total
Jul 31 - Aug 1
9.2/10 Wonderful! (91 reviews)
"The property is close to the Malecon and airport. The shades and windows were dirty. It looked a bit drab inside."
Reviewed on May 15, 2025
River View suites Puerto Santa Ana gye
Puerto Santa Ana, Edificios Riverfront, Bellini, junto al hotel Wyndham., Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $81 total per night from Aug 2 to Aug 3
$81 total
Aug 2 - Aug 3
8.2/10 Very Good! (34 reviews)
"Agradable experiencia! Buena comunicación"
Reviewed on Mar 24, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Puerto Santa Ana
Malecon 2000
4.5/5(180 reviews)
Malecon 2000 is just one of the places to see in Guayaquil, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.
Santa Ana Hill
4.5/5(14 reviews)
Explore the great outdoors at Santa Ana Hill, a lovely green space in Guayaquil. While you're in the area, find time to visit its shops.
U.S. Consulate General
4/5(22 reviews)
U.S. Consulate General is just one of the places to see in San Eduardo, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.
Things to do
Small Group Guayaquil and Cocoa Farm Full-Day Tour
$180
per adult
Guayaquil: Cloud Forest, Hiking & Canyoning Full Day Tour
$309
per adult
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- Hotels near Santa Ana Hill
- Hotels near Las Peñas
- Historic Hotels in Las Peñas
- Hotels near Numa Pompilio Llona Street
- Hotels near Roberto Gilbert Hospital
- Hotels near La Perla
- Gay friendly Hotels in Downtown Guayaquil
- Hotel Wedding Venues Hotels in Downtown Guayaquil
- Resorts & Hotels with Spas in Downtown Guayaquil
- Hotels with Free Parking in Downtown Guayaquil
- Hotels with Restaurants in Downtown Guayaquil
- Hotels with Childcare in Downtown Guayaquil
- Historic Hotels in Downtown Guayaquil
- Luxury Hotels in Downtown Guayaquil
- Pet-friendly Hotels in Downtown Guayaquil
- Hotels with a Pool in Downtown Guayaquil
- Hotels with Laundry Facilities in Downtown Guayaquil
- Hotels near Downtown Guayaquil
- Hotels near Malecon 2000
- Hotels near La Rotonda
- Hotels near Centennial Park
- Hotels near Seminario Park
- Hotels near Guayaquil Metropolitan Cathedral
- Hotels near Municipal Museum of Guayaquil
- Hotels near Sports Federation of Guayas
- Hotels near Kennedy
- Hotels with Restaurants in Kennedy
- Hotels with Room Service in Kennedy
- 5 Star Hotels in Kennedy
- 3 Star Hotels in Kennedy
- Hotels with Free Breakfast in Kennedy
- Hotels with Free Airport Shuttle in Kennedy
- Hotels near Guayaquil Convention Center
- Hotels near Malecon del Salado
- Hotels near Hospital Clinic Kennedy
- Hotels near Policentro
- Hotels near San Marino Mall
- Hotels near Enrique Sotomayor Maternity Hospital
- Hotels near La Puntilla
- Hotels near Simón Bolívar
- Hotels near World Trade Center
- Hotels near Plaza del Sol
- Hotels near Malecon Mall
- Hotels near Santiago de Guayaquil Catholic University
- Hotels near Jose Joaquin de Olmedo Intl.
- Flights from New York (JFK) to Guayaquil (GYE)
- Flights from Jose Joaquin de Olmedo Intl.
- Flights from Miami (MIA) to Guayaquil (GYE)
- Flights from Los Angeles (LAX) to Guayaquil (GYE)
- Flights from Orlando (MCO) to Guayaquil (GYE)
- Flights from Cuenca (CUE) to Guayaquil (GYE)
- Flights from Fort Lauderdale (FLL) to Guayaquil (GYE)
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- Flights from Chicago (ORD) to Guayaquil (GYE)
- Flights from Tampa (TPA) to Guayaquil (GYE)
- Flights from Raleigh (RDU) to Guayaquil (GYE)
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- Flights from Charlotte (CLT) to Guayaquil (GYE)
- Flights from New York (NYC) to Guayaquil (GYE)
- Flights from Panama City (PTY) to Guayaquil (GYE)
- Las Peñas Vacations
- Visit Las Peñas
- El Carmen Hill
- Artisan Market
- La Perla
- Museum of Anthropology and Contemporary Art
- Downtown Guayaquil Vacations
- La Rotonda
- Church of San Francisco
- Visit Downtown Guayaquil
- Centennial Park
- Clock Tower
- Municipal Palace
- Seminario Park
- Simon Bolivar Statue
- Guayaquil Metropolitan Cathedral
- Moorish Clock Tower
- Municipal Museum of Guayaquil
- Sports Federation of Guayas
- Central Market
- Guayaquil Convention Center
- Malecon del Salado
- Visit Kennedy
- Hospital Clinic Kennedy
- Policentro
- San Marino Mall
- Simón Bolívar Vacations
- World Trade Center
- Antonio Neumane Park
- Plaza del Sol
- Mercado Sur
- Santiago de Guayaquil Catholic University
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.