Puerto Santa Ana Vacations from $560
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Your Puerto Santa Ana Vacation
With plenty of highlights as well as some hidden gems, this city is best experienced with a Puerto Santa Ana vacation package. Find somewhere to stay in Downtown Guayaquil, which is good for views, culture and history. Malecon 2000, Banco Pichincha Monumental Stadium and Mall del Sol Commercial Center are just a few of the many attractions you'll want to see during your trip to Puerto Santa Ana. Whoever you're taking time off with and whatever you plan to spend, your ultimate Puerto Santa Ana vacation is just a few clicks away with Expedia.
The Latest Puerto Santa Ana Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Río Guayas by Art Hotels Ecuador
Las Peñas
Save 100% on your flight
Price was $1,749, price is now $1,171 per person
$1,171
per person
Sep 3 - Sep 7
found 15 hours ago
Roundtrip flight included
Miami (MIA) to Guayaquil (GYE)
10/10 Exceptional! (3 reviews)
The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work.
Reviewed on Oct 25, 2025
Mantahost Hotel
Barbasquillo
Price was $987, price is now $730 per person
$730
per person
Aug 20 - Aug 24
found 12 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Guayaquil (GYE)
8.6/10 Excellent! (317 reviews)
Hotel was very clean, A/C worked great, quiet area, staff very accommodating, only problem was food at restaurant took really long time to come out
Reviewed on Mar 6, 2026
Where to stay in Puerto Santa Ana
Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Puerto Santa Ana
Ecuador
Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.
Puerto Santa Ana Hotel Deals
Wyndham Guayaquil Puerto Santa Ana
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Jun 28 to Jun 29
$102 total
Jun 28 - Jun 29
9.2/10 Wonderful! (1,001 reviews)
"The hotel staff was perfect, top notch. The facility was amazing, breakfast was unbelievable, rooms comfortable, view of the water breathtaking."
Reviewed on Jun 19, 2026
River View suites Puerto Santa Ana gye
Puerto Santa Ana, Edificios Riverfront Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $73 total per night from Jul 1 to Jul 2
$73 total
Jul 1 - Jul 2
8.8/10 Excellent! (55 reviews)
"Una vista Hermosa .traquilo ..Todo en su lugar acogedor lo recomiendo ."
Reviewed on Jun 8, 2026
Luxury Suites Riverfront GYE
Puerto Santa Ana Guayaquil Guayas
$80 nightly
The price is $81 total per night from Jul 1 to Jul 2
$81 total
Jul 1 - Jul 2
9.4/10 Exceptional! (107 reviews)
"Amazing stay. The apartment is beautiful, comfortable, and feels truly luxurious. .The location made everything even better. There’s a great market, pharmacy, and excellent restaurants just steps away. It made the whole stay very convenient, and I didn’t need to go anywhere else. Highly ..."
Reviewed on Apr 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Puerto Santa Ana
Malecon 2000
Malecon 2000 is just one of the places to see in Guayaquil, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.
City Mall
During your visit to Guayaquil, you can do some window-shopping at City Mall. Visit the area's cathedral, or simply enjoy its seafood restaurants.
Santa Ana Hill
Explore the great outdoors at Santa Ana Hill, a lovely green space in Guayaquil. While you're in the area, find time to visit its shops.
Things to do
Guayaquil: City Highlights Tour with Cable Car Ride
$118
per adult
Wine Tasting Experience with Tasting Menu
$65
per adult
100% of travellers recommend
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- Hotels near Enrique Sotomayor Maternity Hospital
- Hotels near La Puntilla
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- Hotels near Santiago de Guayaquil Catholic University
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- Flights from New York (JFK) to Guayaquil (GYE)
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- Las Peñas Vacations
- Visit Las Peñas
- El Carmen Hill
- Artisan Market
- La Perla
- Museum of Anthropology and Contemporary Art
- Downtown Guayaquil Vacations
- La Rotonda
- Church of San Francisco
- Visit Downtown Guayaquil
- Centennial Park
- Clock Tower
- Municipal Palace
- Seminario Park
- Simon Bolivar Statue
- Guayaquil Metropolitan Cathedral
- Moorish Clock Tower
- Municipal Museum of Guayaquil
- Sports Federation of Guayas
- Central Market
- Guayaquil Convention Center
- Malecon del Salado
- Visit Kennedy
- Hospital Clinic Kennedy
- Policentro
- San Marino Mall
- Simón Bolívar Vacations
- World Trade Center
- Antonio Neumane Park
- Plaza del Sol
- Mercado Sur
- Santiago de Guayaquil Catholic University
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.