Puerto Santa Ana Vacations from $288
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Your Puerto Santa Ana Vacation
With plenty of highlights as well as some hidden gems, this city is best experienced with a Puerto Santa Ana vacation package. Find somewhere to stay in Downtown Guayaquil, which is good for views, culture and history. Malecon 2000, Banco Pichincha Monumental Stadium and Mall del Sol Commercial Center are just a few of the many attractions you'll want to see during your trip to Puerto Santa Ana. Whoever you're taking time off with and whatever you plan to spend, your ultimate Puerto Santa Ana vacation is just a few clicks away with Expedia.
The Latest Puerto Santa Ana Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Boutique Santa Lucia
Downtown Cuenca
$288
per person
Dec 4 - Dec 6
found 1 day ago
Roundtrip non-stop flight included
Guayaquil (GYE) to Guayaquil (GYE)
9.2/10 Wonderful! (407 reviews)
Our experience was very good. However, the only issue we encountered was the strong kerosene smell on the third floor. The heating lamps located in the interior patio-which at night also operates as a restaurant, where the food is excellent, by the way- emit a very intense kerosene or gasoline odor, and because the patio has a covered roof, the smell ends up accumulating on the third floor.
Reviewed on Sep 19, 2026
Mansión Alcázar Boutique Hotel
Downtown Cuenca
$309
per person
Dec 4 - Dec 6
found 1 day ago
Roundtrip non-stop flight included
Guayaquil (GYE) to Guayaquil (GYE)
9.6/10 Exceptional! (380 reviews)
Nos encanto la propiedad y decoracion,el personal la atencion exelente,definitivamente regresaria,gracias por la atencion y la buena voluntad siempre de atudar
Reviewed on Sep 15, 2026
Where to stay in Puerto Santa Ana
Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Puerto Santa Ana
Ecuador
Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.
Downtown Guayaquil
Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Moorish Clock Tower while you're in town.
Kennedy
1 out of top 10 points of interest in this area
Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.
Urdesa
Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Alban Borja Commercial Center.
Garzota
The restaurants and shopping are a few reasons travelers visit Garzota. Though there aren't many top sights in the neighborhood, you can visit Mall del Sol Shopping Center and City Mall, a few notable attractions nearby.
Puerto Santa Ana Hotel Deals
Wyndham Guayaquil Puerto Santa Ana
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$104 nightly
$116 total
Sep 25 - Sep 26
9.4/10 Exceptional! (1,003 reviews)
"Staff is kind and great"
Reviewed on Sep 21, 2026
River View suites Puerto Santa Ana gye
Puerto Santa Ana, Edificios Riverfront Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$107 nightly
$108 total
Sep 23 - Sep 24
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Puerto Santa Ana attractions
Emporium by The Point
After visiting Emporium by The Point, make a plan to see the other sights and activities in Guayaquil. Attend a sporting event in this walkable area, or simply enjoy its restaurants.
Things to do
Guayaquil: City Highlights Tour with Cable Car Ride
$122
per adult
Wine Tasting Experience with Tasting Menu
$65
per adult
100% of travellers recommend
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- San Francisco Square
- Barco Morgan
- Visit Puerto Santa Ana
- La Perla
- Hospital Clinic Kennedy
- Moorish Clock Tower
- Numa Pompilio Llona Street
- Visit Downtown Guayaquil
- Simon Bolivar Statue
- Sports Federation of Guayas
- Olmedo Monument
- Simón Bolívar Vacations
- Antonio Neumane Park
- Santa Ana Hill
- Malecon 2000
- San Marino Mall
- Enrique Sotomayor Maternity Hospital
- Visit Las Peñas
- Centennial Park
- Guayaquil Metropolitan Cathedral
- Municipal Museum of Guayaquil
- Municipal Palace
- La Rotonda
- Mall del Sol Shopping Center
- Las Peñas Vacations
- Guayaquil Convention Center
- Presley Norton Museum
- Artisan Market
- Downtown Guayaquil Vacations
- Chocolate Museum
- Central Market
- Malecon del Salado
- Museum of Anthropology and Contemporary Art
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.