Find hotels in Downtown, Seneca
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Discover Downtown hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
Quality Inn Seneca Clemson Area US-123
Downtown
8.0 out of 10, Very Good, (664)
"Friendly check in, clean room."
connie
$79 nightly
The price is $87
Dec 14 - Dec 15
Total with taxes and fees
Super 8 by Wyndham Anderson/Clemson Area
18.6 mi from Downtown
6.4 out of 10, (260)
"Service was great and our rooms were clean"
Mary Frances
$60 nightly
The price is $66
Jan 1 - Jan 2, 2026
Total with taxes and fees
Quality Inn Clemson near University
18.4 mi from Downtown
7.0 out of 10, Good, (888)
"Bueno was "
Alejandro
$44 nightly
The price is $48
Dec 25 - Dec 26
Total with taxes and fees
Holiday Inn Anderson by IHG
18.3 mi from Downtown
8.8 out of 10, Excellent, (695)
"Holiday Inn IHG Review (short & guest-friendly): “My stay at the Holiday Inn IHG Hotel was clean, comfortable, and relaxing. The front desk staff were polite and welcoming, and the buffet breakfast was both delicious and well-managed thanks to the helpful service. Overall, a pleasant and enjoyable experience.”
"
Peggy
$109 nightly
The price is $121
Dec 14 - Dec 15
Total with taxes and fees
Americas Best Value Inn Anderson, SC
17.4 mi from Downtown
5.8 out of 10, (151)
"Nice little motel with friendly owners. Beds were a little too firm and breakfast a bit lacking, but for the price, it was fine. We enjoyed our stay. "
Heather
$69 nightly
The price is $77
Dec 6 - Dec 7
Total with taxes and fees
Hilton Garden Inn Anderson
15.9 mi from Downtown
9.0 out of 10, Wonderful, (672)
"Clean Room "
Cynthia
$103 nightly
The price is $115
Dec 11 - Dec 12
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Downtown
Find the best Downtown areas and neighborhoods for the activities you enjoy most.
Serenity Bay
Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
Pine Ridge Point
While Pine Ridge Point isn't home to many top sights, Lake Keowee and World of Energy are some notable places to visit nearby.
Indian Oaks
While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like The Gauntlet and Seneca Historic District.
Keowee Plantation
When in Keowee Plantation, you can plan a visit to Seneca Historic District and Keowee Reservoir, some noteworthy sights in the nearby area.
