Top 10 Hotels in Seneca

See all 46 Hotels in Seneca
Best Western Executive Inn
Best Western Executive Inn

511 Bypass Highway 123, Seneca 29678

2.5 out of 5.0

Situated in Seneca, this hotel is within 9 mi (15 km) of Little John Coliseum, Clemson University, and Larry W. Abernathy …

$79
avg/night
Days Inn Seneca Clemson SC
Days Inn Seneca Clemson SC

11015 N Radio Station Rd, Seneca 29678-1142

2.0 out of 5.0

Situated in Seneca, this motel is within 9 mi (15 km) of Art Circle Gallery, Little John Coliseum, and Larry W. Abernathy …

$55
avg/night
Hotel Tillman
Hotel Tillman

1303 Tiger Blvd, Clemson 29631-1118

2.5 out of 5.0

Located in the heart of Clemson, this hotel is 0.7 mi (1.1 km) from Larry W. Abernathy Waterfront Park and 1.4 mi (2.2 km) …

Get Rates
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area

1011 East North 1st Street, Seneca 29679

2.5 out of 5.0

Situated in Seneca, this hotel is within 9 mi (15 km) of Little John Coliseum, Clemson University, and Larry W. Abernathy …

$101
avg/night
Country Inn & Suites By Carlson Anderson
Country Inn & Suites By Carlson Anderson

116 Interstate Blvd, Anderson 29621-2319

2.5 out of 5.0

Situated in Anderson, this hotel is within 9 mi (15 km) of Anderson Mall, Anderson County Museum, and Agricultural Museum. …

$61
avg/night
Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn

240 Madren Center Drive, Clemson 29634

Situated in Clemson, this hotel is 0.1 mi (0.2 km) from Walker Golf Course and 1.3 mi (2.1 km) from Clemson University. Brook …

$99
avg/night
Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/Clemson

102 Electric City Blvd, Anderson 29621-2306

2.0 out of 5.0

Situated in Anderson, this hotel is within 9 mi (15 km) of Anderson Mall, Agricultural Museum, and Tri-County Technical …

$64
avg/night
Days Inn Clemson
Days Inn Clemson

1387 Tiger Blvd, Clemson 29631-1113

2.0 out of 5.0

Situated in Clemson, this hotel is 0.8 mi (1.3 km) from Larry W. Abernathy Waterfront Park and 1.5 mi (2.4 km) from Clemson …

$75
avg/night
Holiday Inn Express & Suites Clemson
Holiday Inn Express & Suites Clemson

1381 Tiger Blvd, Clemson 29631-1119

2.5 out of 5.0

Situated in Clemson, this hotel is 1.2 mi (2 km) from Larry W. Abernathy Waterfront Park and 1.7 mi (2.8 km) from Clemson …

$94
avg/night
Hampton Inn Clemson
Hampton Inn Clemson

851 Tiger Blvd, Clemson 29631-1480

2.5 out of 5.0

Located in the heart of Clemson, this hotel is 0.7 mi (1.1 km) from Larry W. Abernathy Waterfront Park and 1.7 mi (2.7 km) …

Get Rates

Recent Reviews in Seneca

Hide content

Where to stay in Seneca

Seneca Hotel Guide

Are you planning to spend some nights in Anderson? Hoping to find accommodation in Seneca? Central Seneca has 4 accommodations within easy driving distance.

If you are looking for a hotel that is only easy walking distance of the center of Seneca, Hampton Inn & Suites Seneca-Clemson Area and Best Western Executive Inn will fit the bill.

One of the relatively small number of cheaper hotel options in Seneca is the Quality Inn Seneca / Clemson.

The Hampton Inn Clemson can be found 6 miles from the main part of Seneca. Alternatively, the Liberty Hall Inn & Brandinis Cusine is located 10 miles away. Two more Expedia-registered hotels include the Holiday Inn Express Hotel & Suites Anderson-I-85 and the Holiday Inn Express & Suites Clemson.

If you are keen to see some more of the rolling hills and foothills that are a big feature in this part of the world, you might also spend a few days in other destinations in Upstate South Carolina. No matter if you enjoy popular activities, for example mountain biking, hiking and horse riding, or simply travel around to see the sights you will be able to find suitable places to stay in the region.

The nearest accommodations in Anderson are Clemson and Clemson. Clemson is 8 miles to the east of Seneca, while Clemson is 8 miles to the east. Accommodations in Clemson include the Courtyard Marriott Clemson and University Inn & Conference Center at Clemson. While Clemson hotels include the Hotel Tillman and Days Inn Clemson.

If you love sports and enjoy watching games you might like to visit Bon Secours Wellness Arena, which is 35 miles to the east of Seneca. Book accommodation close to the action at the Courtyard by Marriott Greenville Downtown or the Hampton Inn & Suites Greenville Downtown RiverPlace.

Situated 45 miles away from Seneca is Greenville-Spartanburg International Airport. Stay nearby at Greenville Marriott or Courtyard Greenville-Spartanburg by Marriott.