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Find Hotels in Seneca, SC

Lakefront! Dock Available. 4 Bedroom 4 Bath Condo 1.5 Miles From Clemson Stadium
4.8/5Exceptional! (6 reviews)
Great location!

"Everything was as advertised and perfect for what we were looking for! Sam was very accommodating and very responsive when we had questions. Highly recommend!"…"

Reviewed on Jul 7, 2020

Lakefront! Dock Available. 4 Bedroom 4 Bath Condo 1.5 Miles From Clemson Stadium
Lake Hartwell Lakefront Home Near Clemson University Baseball and Other Events
4.8/5Exceptional! (12 reviews)
Great place on the Lake!

"Tucked in a deep cove in a pretty setting. Great dock and back yard. We tied up our pontoon and really enjoyed it. House is well equipped."…"

Reviewed on Jul 3, 2020

Lake Hartwell Lakefront Home Near Clemson University Baseball and Other Events
Fall fun at the Cabin! Convenient to Lake Keowee and Clemson
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4.01 mi from city center
4.7/5Exceptional! (56 reviews)
Nice Cabin, close to different attactions

"The cabin is in good shape. It looks better in photo but very comfortable. The bonfire is a plus. There is not much to do walking distance but 25-45 min away of different waterfalls. Would be nice to have at least shampoo in the bathrooms."…"

Reviewed on Jan 17, 2020

Fall fun at the Cabin! Convenient to Lake Keowee and Clemson
Lake House Near Clemson, Priv. Dock, Wifi, 60" TV, Grill, Pedal Boat, Deep Water
4.8/5Exceptional! (72 reviews)
Anniversary Get Away

"The property is situated in a beautiful, wooded area. We watched deer cross the property while enjoying breakfast on the screened porch. The dock is a great place to relax and enjoy water activities, away from the high-traffic area of the lake. We will definitely return!"…"

Reviewed on Jun 18, 2020

Lake House Near Clemson, Priv. Dock, Wifi, 60" TV, Grill, Pedal Boat, Deep Water
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
Free CancellationReserve now, pay when you stay
The price is $104 per night
5.17 mi from city center
4.4/5Wonderful! (85 reviews)

"The rooms were very clean and the staff was friendly."…"

Reviewed on Jun 29, 2020

Tru by Hilton Seneca Clemson
Hampton Inn & Suites Seneca-Clemson Area, SC
2.5 out of 5
1011 East North 1st Street, Seneca, SC
Free CancellationReserve now, pay when you stay
The price is $98 per night
1.21 mi from city center
4.7/5Exceptional! (286 reviews)

"It was clean and friendly. Convenient location and easy to find."…"

Reviewed on Jun 9, 2020

Hampton Inn & Suites Seneca-Clemson Area, SC
Beautiful Waterfront Retreat on Lake Keowee W/ Clemson Game day Parking Pass
5/5Exceptional! (3 reviews)
Great place on the lake

"Great place on the lake"…"

Reviewed on Jul 8, 2020

Beautiful Waterfront Retreat on Lake Keowee W/ Clemson Game day Parking Pass
Lake Hartwell Home w/ Dock, 9.5mi to Clemson!
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6.03 mi from city center
5/5Exceptional! (4 reviews)
Relaxing

"Enjoyed our stay and the much needed R&R. The house was clean and comfortable. Would recommend to friends and would stay again."…"

Reviewed on Jul 6, 2020

Lake Hartwell Home w/ Dock, 9.5mi to Clemson!
Beautiful Lake Keowee Home Sleeps 15 GET Away AND Relax!!
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5.91 mi from city center
4.9/5Exceptional! (21 reviews)
Overall great stay

"We had a wonderful time during our stay at this home. There was a very large inconvenience at check in but Jeff is very responsive and made it right as quickly as possible. The home has everything you need for a wonderful stay on the lake and attention is paid to detail."…"

Reviewed on Jul 8, 2020

Beautiful Lake Keowee Home Sleeps 15 GET Away AND Relax!!
Deepwater Cove on Beautiful Lake Keowee Complete With Dock and Kayaks
4.9/5Exceptional! (35 reviews)
July 4th Adult Vacation

"A group of 10 family and friends stayed for a long weekend. There was plenty of room for everyone to sleep and have their own space. The interior of the house is bigger than it appears in the pictures and is very clean and updated. The kitchen is stocked with most anything you should need. There ..."…"

Reviewed on Jul 6, 2020

Deepwater Cove on Beautiful Lake Keowee Complete With Dock and Kayaks
? Spacious Lake Hartwell Home With Cozy Cabin Appeal, 15 Mins to Clemson? Wifi
5/5Exceptional! (60 reviews)
Best spacious and relaxing getaway!

"We stayed 10 days at this Seneca lake house. The five of us had plenty of space within the house. There are three bedrooms, a large kitchen/ dinning area, three full bathrooms, a gorgeous living room fireplace and a game room with a pool table and games galore. The basketball hoop by the garage was ..."…"

Reviewed on Jul 4, 2020

? Spacious Lake Hartwell Home With Cozy Cabin Appeal, 15 Mins to Clemson? Wifi
7mi to Clemson New Custom Luxury Lakehome Game Room+ Shuffleboard + Fire Pit
4.9/5Exceptional! (52 reviews)
All was outstanding. Only complaint was the water depth off dock was not sufficient for diving.

"It was a pleasing week in a lovely home on the Lake Keowee cove."…"

Reviewed on Jul 8, 2020

7mi to Clemson New Custom Luxury Lakehome Game Room+ Shuffleboard + Fire Pit
Perfect Lake Keowee Waterfront Vacation Home With Boat and Jet Ski Rentals
4.9/5Exceptional! (146 reviews)
Peaceful getaway

"The house is spacious, well equipped and very comfortable. It’s located on a very quiet, peaceful area of the lake. I loved sitting on the comfortable screen porch, we ate most meals out there looking at the lake. Mike and Tyler we’re always available to answer any questions. Attention was paid to ..."…"

Reviewed on Jun 30, 2020

Perfect Lake Keowee Waterfront Vacation Home With Boat and Jet Ski Rentals
Fishing Cabin - Keowee 2 Bedrooms, 2 Bathrooms - Fishing - Kayaking - Porch
5/5Exceptional! (9 reviews)
Sweet cabin

"Great place to get away and unplug! It was a great idea to have a couple kayaks there to get out on the lake. Location was private."…"

Reviewed on Jul 1, 2020

Fishing Cabin - Keowee 2 Bedrooms, 2 Bathrooms - Fishing - Kayaking - Porch
Lakefront Keowee Cabin 14 Miles to Clemson w/ Hot Tub
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3.97 mi from city center
5/5Exceptional! (7 reviews)
Ladies Weekend

"This was a fabulous house for our yearly ladies retreat. The kitchen is large and accommodating, the decks are amazing. The house was very clean and Amanda was super prompt to answer questions. Check-in/Check-out was super easy as well. The only negative on this property is parking. You can really ..."…"

Reviewed on Mar 12, 2020

Lakefront Keowee Cabin 14 Miles to Clemson w/ Hot Tub
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Visiting Seneca

Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses.

  • You'll find 90 Expedia hotels and other accommodations in the larger area of Anderson
  • The closest major airport is in Greenville, SC (GSP-Greenville-Spartanburg Intl.), 44.2 mi (71.1 km) from the city center

Sightseeing and Staying in Seneca

Places to visit in the larger region include Little John Coliseum, Memorial Stadium, and Walker Golf Course. Additionally, you'll find Clemson University and Brooks Center for the Performing Arts in the area.

As you plan your holiday getaway, you'll find 32 hotels and other lodging options to pick from in Seneca. Here you'll find highly ranked ones based on Expedia user reviews:

  • Hampton Inn & Suites Seneca-Clemson Area, SC - With a stay at this 2.5-star hotel, guests can enjoy access to free breakfast and an outdoor pool, along with free WiFi. It's a favorite with Expedia travelers for its breakfast and pool.
  • Best Western Executive Inn - Our customers like the breakfast and overall value at this hotel. With a stay at this 2.5-star hotel, guests can enjoy access to free breakfast and an outdoor pool, along with free WiFi.
  • Days Inn by Wyndham Seneca - This 2-star motel features free breakfast, an outdoor pool, and free WiFi. Expedia customers like its pool and proximity to shopping.

Dressing for Seneca

  • Between January and March, you can expect average temperatures of 68°F during the day and 30°F at night
  • From April to June, the average during the day is 89°F, while the average at night is 43°F
  • July through September has daytime averages of 90°F with nighttime averages of 55°F
  • In October-December, you can expect daytime averages of 77°F and nighttime averages of 30°F
  • About 50.16 inches of rain falls on Seneca each year
  • Usually July and August are the hottest months with an average of 89°F, whereas January and December are often coldest, averaging 32°F

Frequently asked questions

Where is the best place for a stay in Seneca?
Hampton Inn & Suites Seneca-Clemson Area, SC is ranked highly by Expedia customers. This hotel offers free breakfast and free WiFi. Traveler reviews also recommend Tru by Hilton Seneca Clemson and Best Western Seneca-Clemson as top choices for your visit.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation’s cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on “Search”, then use the filter option “free cancellation” to view top deals in Seneca.
Where can I learn more about changing or cancelling my trip to Seneca?
To find more details about updating your trip to Seneca or cancelling it, click here.
What's the best budget-friendly accommodation in Seneca?
Based on reviews, Days Inn by Wyndham Seneca / Clemson Area is a popular 2-star property for our travelers looking for an economical choice, and features free breakfast and free WiFi. Other good options for your budget-friendly stay include Best Western Seneca-Clemson and Quality Inn Seneca US-123.
What's the best place to stay for a family vacation to Seneca?
Best Western Seneca-Clemson is a hotel with an outdoor pool and free parking, and it’s a top choice on Expedia for families. Hampton Inn & Suites Seneca-Clemson Area, SC is another good choice for your stay with the kids.
What's the best pet-friendly accommodation in Seneca?
Days Inn by Wyndham Seneca / Clemson Area is a top property for people traveling with their pets, and offers a seasonal outdoor pool and laundry facilities for its human guests. Quality Inn Seneca US-123 is another good choice if you’re bringing your pet along.
What are some hotels with pools in Seneca?
Hampton Inn & Suites Seneca-Clemson Area, SC is a top hotel with a seasonal outdoor pool, free breakfast, and free WiFi. Other choices that feature an onsite pool include Best Western Seneca-Clemson and Days Inn by Wyndham Seneca / Clemson Area.

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