Esquilino Vacations from $833

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Your Esquilino Vacation

Avoid the hassle of travel planning with an Esquilino vacation package. With everything organized before you take off, all that's left to do is enjoy this commercial neighborhood's history, dining and culture. Not sure what to do and see during your trip to Esquilino? Nearby attractions like St. Peters Basilica, Roman Forum and Pantheon are great places to start. Don't just imagine it — turn it into reality! Book your ideal Esquilino vacation with Expedia and travel your way.

The Latest Esquilino Vacation Packages

Price found within the past 48 hours. Click for updated prices.
JC Hotel

JC Hotel

4 out of 5
Fonte Ostiense
Save 100% on your flight
Price was $1,401, price is now $833 per person
$833
per person
Mar 24 - Mar 29
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
8/10 Very Good! (133 reviews)
Relais de la Poste

Relais de la Poste

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,031, price is now $1,133 per person
$1,133
per person
Feb 28 - Mar 6
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.2/10 Wonderful! (612 reviews)
Heating is not good enough

Reviewed on Jan 8, 2026

Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
Price was $1,389, price is now $840 per person
$840
per person
Apr 4 - Apr 7
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (267 reviews)
Breakfast was fresh and healthy each morning. All of the staff were extremely nice and helpful. Loved my stay here, would stay here again and will recommend to friends.

Reviewed on Dec 28, 2025

Where to stay in Esquilino

Find the best Esquilino areas and neighborhoods for the activities you enjoy most. Learn more about Esquilino
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Esquilino Hotel Deals

Napoleon Hotel

Napoleon Hotel

4 out of 5
Piazza Vittorio Emanuele II 105 Rome RM
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $124 total per night from Jan 10 to Jan 11
$124 total
Jan 10 - Jan 11
Total with taxes and fees
8.4/10 Very Good! (1,014 reviews)
Staff was welcoming and kind. Room was big and the location was great! Highly recommend trying the restaurants around the hotel as well.

Reviewed on Jan 4, 2026

Napoleon Hotel
Hotel Terminal

Hotel Terminal

3 out of 5
Via Principe Amedeo 103 Rome RM
Fully refundableReserve now, pay when you stay
$47 nightly
The price is $66 total per night from Jan 11 to Jan 12
$66 total
Jan 11 - Jan 12
Total with taxes and fees
7.4/10 Good! (349 reviews)
It had the necessary things for a tourist, plus it was a quiet place to stay at. It had quick access to aajor Basilica and transportation. We would stay here again.

Reviewed on Jan 7, 2026

Hotel Terminal
Hotel Contilia

Hotel Contilia

3 out of 5
Via Principe Amedeo 81 Rome RM
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $120 total per night from Jan 12 to Jan 13
$120 total
Jan 12 - Jan 13
Total with taxes and fees
7.2/10 Good! (997 reviews)
After a last seconf cancelation by a different host, I ended up at this property and have a very good expperience. The staff were kind in helping me get my reservation changed over. The room was spotless and cleaned daily. Overall, a great experience!

Reviewed on Nov 10, 2025

Hotel Contilia
See all 702 properties in Esquilino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Esquilino

Piazza Santa Maria Maggiore

Piazza Santa Maria Maggiore

Find out about the history of Rome when you take a trip to Piazza Santa Maria Maggiore. Experience the acclaimed art scene and fascinating museums in this vibrant area.

Piazza Santa Maria Maggiore
Palm Trees in the Evening Light

Piazza Vittorio Emanuele II

Explore the great outdoors at Piazza Vittorio Emanuele II, a lovely green space in Rome. Experience the acclaimed art scene and fascinating museums in this vibrant area.

Piazza Vittorio Emanuele II

Basilica di Santa Croce in Gerusalemme

Find out about the history of Rome when you take a trip to Basilica di Santa Croce in Gerusalemme. Discover the acclaimed art scene and stunning cathedral in this vibrant area.

Basilica di Santa Croce in Gerusalemme

Things to do

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$35
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$77
per adult
90% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$27
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.