
Esquilino Vacations from $833
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Your Esquilino Vacation
Avoid the hassle of travel planning with an Esquilino vacation package. With everything organized before you take off, all that's left to do is enjoy this commercial neighborhood's history, dining and culture. Not sure what to do and see during your trip to Esquilino? Nearby attractions like St. Peters Basilica, Roman Forum and Pantheon are great places to start. Don't just imagine it — turn it into reality! Book your ideal Esquilino vacation with Expedia and travel your way.
The Latest Esquilino Vacation Packages



Hotel Delle Civette
Reviewed on Dec 28, 2025
Where to stay in Esquilino

Rome City Centre
Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.
Esquilino Hotel Deals

Napoleon Hotel
Staff was welcoming and kind. Room was big and the location was great! Highly recommend trying the restaurants around the hotel as well.
Reviewed on Jan 4, 2026

Hotel Terminal
It had the necessary things for a tourist, plus it was a quiet place to stay at. It had quick access to aajor Basilica and transportation. We would stay here again.
Reviewed on Jan 7, 2026

Hotel Contilia
After a last seconf cancelation by a different host, I ended up at this property and have a very good expperience. The staff were kind in helping me get my reservation changed over. The room was spotless and cleaned daily. Overall, a great experience!
Reviewed on Nov 10, 2025
Discover the most popular places to visit in Esquilino

Piazza Santa Maria Maggiore
Find out about the history of Rome when you take a trip to Piazza Santa Maria Maggiore. Experience the acclaimed art scene and fascinating museums in this vibrant area.

Piazza Vittorio Emanuele II
Explore the great outdoors at Piazza Vittorio Emanuele II, a lovely green space in Rome. Experience the acclaimed art scene and fascinating museums in this vibrant area.
Basilica di Santa Croce in Gerusalemme
Find out about the history of Rome when you take a trip to Basilica di Santa Croce in Gerusalemme. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
Things to do

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica























