Esquilino Vacations from $1,003
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Esquilino Vacation
Avoid the hassle of travel planning with an Esquilino vacation package. With everything organized before you take off, all that's left to do is enjoy this commercial neighborhood's history, dining and culture. Not sure what to do and see during your trip to Esquilino? Nearby attractions like St. Peters Basilica, Roman Forum and Pantheon are great places to start. Don't just imagine it — turn it into reality! Book your ideal Esquilino vacation with Expedia and travel your way.
The Latest Esquilino Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Relais de la Poste
Rome City Centre
$1,003
per person
Nov 30 - Dec 5
found 4 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.2/10 Wonderful! (734 reviews)
The only downside of our stay was the room temperature. The room was quite warm, especially at night, which made it uncomfortable to sleep. Other than that, we had a very pleasant stay, and this was our only complaint.
Reviewed on Oct 15, 2026
Hotel Delle Civette
Nomentano
$1,140
per person
Jan 1 - Jan 6
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (323 reviews)
A beautiful building. Scrupulously clean. Staff top to bottom were lovely.
Room very spacious with high ceilings and lovely windows with shutters and blackout curtains. Bathroom was great and had a powerful shower. Beds and pillows were very comfortable for us…firm but not hard. 2 wardrobes with drawers and bedside tables also had drawers. Safe in the wardrobe. There’s a heating radiator and air con in the room.
Convenient location. 10 mins walk to Bologna metro. In total 30 mins to most landmarks (some less). We also used the buses frequently. Excellent bus service in Rome. Breakfast…lovely staff…but quite basic.
A lovely location and quiet.
Wouldn’t hesitate to recommend.
Thank-you for a lovely stay.
Reviewed on Oct 13, 2026
Il Campo Marzio
Rome City Centre
$1,287
per person
Nov 19 - Nov 26
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Rome (FCO)
8.6/10 Excellent! (199 reviews)
Unfortunately, our stay was a very disappointing experience from beginning to end. The property did not meet the standards we expected, and the overall experience was nothing like what was advertised.
Upon arrival, we immediately noticed several issues with the property and felt uncomfortable staying there. The condition of the accommodation was disappointing, and there were concerns regarding cleanliness, maintenance, and the overall quality of the room. The property did not feel properly prepared for guests.
Communication and customer service were also frustrating. We expected the staff/management to be responsive and helpful when concerns were brought to their attention, but the situation was not handled in a way that made us feel valued as guests.
Ultimately, we decided that the best option was to leave and find alternative accommodations rather than continue our stay. For the price we paid, the experience was completely unacceptable.
I would strongly recommend that future guests carefully consider other options before booking. Based on our experience, I would not stay here again or recommend this property to others.
Reviewed on Oct 8, 2026
U-Visionary Roma Hotel
Rome City Centre
$1,706
per person
Nov 19 - Nov 24
found 5 hours ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (511 reviews)
Highly recommend this hotel! Great location (very close to the Trevi fountain). Room was always spotless thanks to housekeeping!
Reviewed on Oct 15, 2026
Where to stay in Esquilino
Find the best Esquilino areas and neighborhoods for the activities you enjoy most. Learn more about Esquilino
Rome City Centre
9 out of top 10 points of interest in this area
Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.
Rome Historic Centre
Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.
Trastevere
Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.
Monti
Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.
Trevi
Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.
Esquilino Hotel Deals
Napoleon Hotel
Piazza Vittorio Emanuele II 105 Rome RM
Fully refundableReserve now, pay when you stay
$118 nightly
$129 total
Nov 13 - Nov 14
Total with taxes and fees
8.6/10 Excellent! (1,057 reviews)
"Great location near the Metro. Well maintained with helpful friendly staff. Excellent breakfast to start off your day!"
Reviewed on Oct 15, 2026
Hotel Palladium Palace
Via Gioberti 36 Rome RM
Fully refundableReserve now, pay when you stay
$145 nightly
$176 total
Nov 15 - Nov 16
Total with taxes and fees
The Cross Hotel
Via S.Croce in Gerusalemme, 40 Rome RM
Fully refundableReserve now, pay when you stay
$83 nightly
$104 total
Nov 8 - Nov 9
Total with taxes and fees
8.8/10 Excellent! (706 reviews)
"Staff was attentive and helpful. Not enough towels, Two guest and only 4 hangers, had to ask for 2 more. First time I didn’t pack my own shampoo and they didn’t have any (just body soap combines hair-wash). I walked out to see the front desk and couldn’t get back into my unit (locked out) due to ..."
Reviewed on Oct 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Esquilino attractions
Piazza Santa Maria Maggiore
8.0/10 (7 reviews)
Find out about the history of Rome when you take a trip to Piazza Santa Maria Maggiore. Experience the acclaimed art scene and fascinating museums in this vibrant area.
Piazza Vittorio Emanuele II
8.6/10 (4 reviews)
Explore the great outdoors at Piazza Vittorio Emanuele II, a lovely green space in Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.
Basilica di Santa Croce in Gerusalemme
9.4/10 (3 reviews)
Find out about the history of Rome when you take a trip to Basilica di Santa Croce in Gerusalemme. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
Historic Museum of the Liberation
You can browse the exhibits at Historic Museum of the Liberation, a museum with a storied past, during your travels to Rome. Experience the acclaimed art scene and fascinating museums in this vibrant area.
Museo degli Strumenti Musicali
You can browse the exhibits at Museo degli Strumenti Musicali, a museum with a storied past, during your travels to Rome. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
Teatro Ambra Jovinelli
Enjoy a performance at Teatro Ambra Jovinelli, a storied theater in Rome. Discover the fascinating museums and churches in this vibrant area.
Republican Tombs
Find out about the history of Rome with a stop at Republican Tombs. Make time for the stunning cathedral and local tours in this vibrant area.
Palace of the Holy Steps
You can learn about the history of Rome when you stop by Palace of the Holy Steps (Santuario della Scala Santa). Visit the stunning cathedral and notable monuments in this vibrant area.
Things to do
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
$30
per adult
84% of travellers recommend
Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group
$130
per adult
94% of travellers recommend
Pasta-Making Class: Cook, Dine & Drink With A Local Chef
$54
per adult
100% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.