Esquilino Vacations from $868

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Your Esquilino Vacation

Avoid the hassle of travel planning with an Esquilino vacation package. With everything organized before you take off, all that's left to do is enjoy this commercial neighborhood's history, dining and culture. Not sure what to do and see during your trip to Esquilino? Nearby attractions like St. Peters Basilica, Roman Forum and Pantheon are great places to start. Don't just imagine it — turn it into reality! Book your ideal Esquilino vacation with Expedia and travel your way.

The Latest Esquilino Vacation Packages

Price found within the past 48 hours. Click for updated prices.
CC Palace Hotel Roma

CC Palace Hotel Roma

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,368, price is now $868 per person
$868
per person
Dec 7 - Dec 12
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.8/10 Exceptional! (351 reviews)
I loved the service from the minute we arrived to the minute we checked out. The staff are friendly and jovial. The facility was topnotch.

Reviewed on Sep 22, 2025

Apollo Boutique Hotel

Apollo Boutique Hotel

4 out of 5
Vatican
Save 100% on your flight
Price was $1,744, price is now $1,121 per person
$1,121
per person
Nov 4 - Nov 10
found 6 hours ago
Roundtrip flight included
New York (NYC) to Rome (FCO)
9.2/10 Wonderful! (116 reviews)
GREAT PLACE TO STAY! BED WAS REALLY COMFORTABLE AND STAFF WAS EXTREMELY NICE....

Reviewed on Jul 28, 2025

Vibe Nazionale

Vibe Nazionale

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,514, price is now $977 per person
$977
per person
Nov 15 - Nov 22
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
8/10 Very Good! (63 reviews)
Very small room no toiletries,poor breakfast

Reviewed on Sep 21, 2025

TB Place Roma

TB Place Roma

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,817, price is now $1,207 per person
$1,207
per person
Dec 7 - Dec 12
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.2/10 Wonderful! (43 reviews)
We pretty much likes everything about the property. My wife and I travel a lot and normally go to very good hotels which are bigger, but we wanted to try a boutique hotel this time and it did not disappoint. We stayed for 6 nights. For starters, their people are wonderful, with a special shout out to Martina at the front desk and the young lady that runs the breakfast (we should know her name). The location is great, the hotel is in great condition. We stayed in a junior suite and it was a really good size. We tend to be on the picky side, and honestly we can’t find anything bad to say. Keep it up!

Reviewed on Jun 1, 2025

Piazza di Spagna Suite de Charme

Piazza di Spagna Suite de Charme

1 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,325, price is now $886 per person
$886
per person
Dec 4 - Dec 9
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.2/10 Wonderful! (221 reviews)
The location, the room was very nice - and staff amazing. The bed sheets were super soft and u can’t beat the location. I would definitely stay there again when I return to Rome.

Reviewed on Aug 30, 2025

Where to stay in Esquilino

Find the best Esquilino areas and neighborhoods for the activities you enjoy most. Learn more about Esquilino
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Esquilino Hotel Deals

Napoleon Hotel

Napoleon Hotel

4 out of 5
Piazza Vittorio Emanuele II 105, Rome, RM
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $205 total per night from Nov 2 to Nov 3
$205 total
Nov 2 - Nov 3
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
"The hotel itself is quite nice. The rooms very comfortable. Everything was quite clean. The restaurant in the hotel was nice. The rooftop bar was fun. The hotel is conveniently located near enough to the train station to walk, but far enough to not be bothered by it. Naples, unfortunately is not ..."

Reviewed on Sep 29, 2025

Napoleon Hotel
Hotel Morgana

Hotel Morgana

4 out of 5
Via Filippo Turati 31 33 35, Rome, RM
$158 nightly
The price is $192 total per night from Nov 4 to Nov 5
$192 total
Nov 4 - Nov 5
Total with taxes and fees
8.2/10 Very Good! (998 reviews)
"I would highly recommend others to try this hidden gem in Rome. Not only are the staff to be commended for their wonderful help and guidance, but the overall stay was for me, just superb. It’s a place I would return too without hesitation."

Reviewed on Sep 24, 2025

Hotel Morgana
NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

5 out of 5
Piazza Dei Cinquecento, 90, Rome, RM
Fully refundableReserve now, pay when you stay
$366 nightly
The price is $426 total per night from Nov 1 to Nov 2
$426 total
Nov 1 - Nov 2
Total with taxes and fees
9/10 Wonderful! (1,000 reviews)
"Good location and much more peaceful than the historic centres. Excellent breakfast buffet. Helpful staff."

Reviewed on Sep 12, 2025

NH Collection Roma Palazzo Cinquecento
See all 691 properties in Esquilino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Esquilino

Piazza Santa Maria Maggiore

Piazza Santa Maria Maggiore

3.5/5(3 reviews)

Find out about the history of Rome when you take a trip to Piazza Santa Maria Maggiore. Experience the acclaimed theater scene and fascinating museums in this vibrant area.

Piazza Santa Maria Maggiore
Palm Trees in the Evening Light

Piazza Vittorio Emanuele II

5/5(1 review)

Explore the great outdoors at Piazza Vittorio Emanuele II, a lovely green space in Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Piazza Vittorio Emanuele II

Basilica di Santa Croce in Gerusalemme

5/5(1 review)

Find out about the history of Rome when you take a trip to Basilica di Santa Croce in Gerusalemme. Discover the acclaimed theater scene and notable monuments in this vibrant area.

Basilica di Santa Croce in Gerusalemme

Things to do

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$40
per adult
88% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$34
per adult
82% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$35
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.