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Santa Ana can be found around 45 miles to the south of Esquipulas, while San Salvador is 60 miles to the south.
Esquipulas Basilica and Mine Cave Tourist Center are equally worth visiting.
If you're eager to explore more of the area, you'll find Montecristo National Park 13 miles to the south and Metapan 18 miles to the south.
Don't forget to head to Copan Ruinas. It's approximately 20 miles to the northeast of Esquipulas and it features some excellent attractions, such as Aguas Termales, Rastrojon and Las Sepulturas Archaeological Site. Copan Ruins and Túnel Rosalila & Túnel de los Jaguares are some more sites if you have extra time.
Enliven your taste buds in this region's dining venues.
Beans (frijoles) and chicken are a pair of notable ingredients that you'll get to know, if you don't already!
Of course, your trip wouldn't be complete if you don't sample chiles rellenos (bell peppers stuffed with meat and vegetables) and gallo en chicha (chicken stew).
Delicious desserts, such as coconut flan, are definitely worth trying.
Get yourself a pint of Victoria, one of this region's homegrown beers.
If you're in search of an alcohol-free beverage, order a tea.
Celebrate a successful day with a glass of the region's finest wines. Château DeFay White Merlot and Château DeFay Cabernet Sauvignon/Merlot are definitely worth trying out.
Learning the local language is a great way to understand a different culture, so make the effort to learn to say a few handy Spanish words and phrases before you arrive. Buenas noches is Spanish for good evening. ¿Cuánto cuesta? (how much is this?) is also good to know.
A lively national celebration, Independence Day is something you won't want to miss. It takes place on the 15th of September.
We all wish vacations could last forever. However, you'll have to bid "Hasta la vista" to Esquipulas eventually. At least once you get back home you'll have loads of crazy stories to tell!
To get your flight homeward, make your way to the nearest airport. You'll find it 80 miles to the west.