Title: Visit Essex: 2026 Travel Guide for Essex, Missouri | Expedia.com [Hotels in Essex](https://expedia.com/Essex-Hotels.d553248634983169000.Travel-Guide-Hotels)[Vacation Rentals in Essex](https://expedia.com/Essex-Vacation-Rentals.d553248634983169000.Travel-Guide-VacationRentals)[Car Rentals in Essex](https://expedia.com/Car-Rentals-In-Essex.d553248634983169000.Car-Rental-Guide)[Essex Vacation Packages](https://expedia.com/Essex.d553248634983169000.Destination-Travel-Guides) # Essex, MO ## Travel Guide ## Visit Essex - Essex Hotel Deals - Vacation Rentals in Essex ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Sikeston, MO 2608 East Malone Ave, Miner Sikeston MO $90 nightly $103 total Feb 12 - Feb 13 Total with taxes and fees Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ... 9.4/10 Exceptional! (1,001 reviews) Great Reviewed on Feb 4, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F12%2F2026&endDate=2%2F13%2F2026&selected=24210&PinnedHotelID=24210&HadPinnedHotel=true®ionId=553248634983169000) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO Fully refundableReserve now, pay when you stay $96 nightly $109 total Feb 28 - Mar 1 Total with taxes and fees Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ... 8.8/10 Excellent! (474 reviews) Great place for an overnight stay. I will be back! Reviewed on Jan 26, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F28%2F2026&endDate=3%2F1%2F2026&selected=25178175&PinnedHotelID=25178175&HadPinnedHotel=true®ionId=553248634983169000) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Plus Sikeston 120 S Interstate Drive Sikeston MO $85 nightly $97 total Feb 22 - Feb 23 Total with taxes and fees Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ... 8.2/10 Very Good! (1,001 reviews) Great breakfast. Clean room Quiet Reviewed on Jan 31, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F22%2F2026&endDate=2%2F23%2F2026&selected=8420572&PinnedHotelID=8420572&HadPinnedHotel=true®ionId=553248634983169000) [See all 32 properties in Essex](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=2%2F9%2F2026&endDate=2%2F10%2F2026®ionId=553248634983169000) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Charming 3-bedroom house in delightful Advance with AC, WiFi](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/a162857d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Charming 3-bedroom house in delightful Advance with AC, WiFi Advance MO Book a stay at this family-friendly vacation home in Advance. Enjoy laundry facilities, an in-room coffeemaker, and air conditioning. 10/10 Exceptional! (4 reviews) Everything was in great condition. Great stay Reviewed on Nov 24, 2025 [](https://expedia.com/Advance-Hotels-Charming-3-Bedroom-House-In-Delightful-Advance-With-AC.h103362449.Hotel-Information) ![Shop House located 8 miles from Otter Slough Conservation Area](https://images.trvl-media.com/lodging/101000000/100180000/100176800/100176703/eb6bb38f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Shop House located 8 miles from Otter Slough Conservation Area Dexter MO Stay at this vacation home in Dexter. Enjoy a garden, laundry facilities, and patios. Popular attractions The Heritage House and Keller Veteran Memorial are ... 10/10 Exceptional! (1 review) Close to town, clean, friendly owner. Reviewed on Jan 12, 2026 [](https://expedia.com/Dexter-Hotels-Shop-House-Located-8-Miles-From-Otter-Slough-Conservation-Area.h100176703.Hotel-Information) ![Dexter Homestead. Very Cozy & NEW Remodel !](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/65f4c520_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Dexter Homestead. Very Cozy & NEW Remodel ! Dexter MO Book a stay at this family-friendly vacation home in Dexter. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Keller Veteran Memorial and ... 7.8/10 Good! (30 reviews) Stayed many times. Nice and comfortable Reviewed on Dec 21, 2025 [](https://expedia.com/Dexter-Hotels-Dexter-Homestead-Very-Cozy-NEW-Remodel.h63162828.Hotel-Information) [See all properties in Essex](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248634983169000&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Essex hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983169000&startDate=2026-02-08&endDate=2026-02-09)[Feb 8 - Feb 9](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983169000&startDate=2026-02-08&endDate=2026-02-09) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983169000&startDate=2026-02-09&endDate=2026-02-10)[Feb 9 - Feb 10](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983169000&startDate=2026-02-09&endDate=2026-02-10) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983169000&startDate=2%2F13%2F2026&endDate=2%2F15%2F2026)[Feb 13 - Feb 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983169000&startDate=2%2F13%2F2026&endDate=2%2F15%2F2026) ## Cities near Essex ![The Monopoly Marsh at sunrise at Mingo National Wildlife Refuge near Puxico, Missouri. ..Photo by Kyle Spradley | © Kyle Spradley Photography | www.kspradleyphoto.com](https://images.trvl-media.com/place/55097/ec3c1c0a-7e88-4719-80b1-ea01eb0550e4.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Dexter ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Sikeston - Cities near Essex - Places of interest [Dexter](https://expedia.com/Dexter.dx55097)[Sikeston](https://expedia.com/Sikeston.dx6058766)[Bernie](https://expedia.com/Bernie.dx3000349284)[Canalou](https://expedia.com/Canalou.dx3000349311)[Catron](https://expedia.com/Catron.dx3000349317) - [Mississippi River ](https://expedia.com/Mississippi-River-United-States-of-America.d6209928.Vacation-Attraction) - [New Madrid Historical Museum ](https://expedia.com/New-Madrid-Historical-Museum-New-Madrid.d553248621532655748.Vacation-Attraction) - [Marston Community Center ](https://expedia.com/Marston-Community-Center-Marston.d553248622945532712.Vacation-Attraction) - [The Heritage House ](https://expedia.com/The-Heritage-House-Dexter.d553248621592342444.Vacation-Attraction) - [Sikeston Depot Museum ](https://expedia.com/Sikeston-Depot-Museum-Sikeston.d6305602.Vacation-Attraction) - [Central Park ](https://expedia.com/Central-Park-Sikeston.d6305608.Vacation-Attraction) - [Dexter Welcome Center Depot and Museum ](https://expedia.com/Dexter-Welcome-Center-Depot-And-Museum-Dexter.d553248621592342445.Vacation-Attraction) - [Stoddard County Civil War Memorial Cemetery ](https://expedia.com/Stoddard-County-Civil-War-Memorial-Cemetery-Dexter.d553248621532655747.Vacation-Attraction) - [Hunter-Dawson State Historic Site ](https://expedia.com/Hunter-Dawson-State-Historic-Site-New-Madrid.d553248621532655794.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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