Florence County Vacations & Trips from $419

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Your Florence County Vacation

Leave the planning up to us with a Florence County vacation package. With everything arranged before you leave home, the only thing left to do is sit back, chill out and enjoy this destination's countless delights. A trip to Florence County wouldn't be complete without getting to some of its best cities, starting with Florence. Two of the most popular attractions here include Magnolia Mall and Mcleod Regional Medical Center. Lake City is another favorite city with Florence County travelers. Visitors to this exciting destination enjoy The Country Club at Lake City and Moore Farms Botanical Garden. Expedia is a one-stop shop for planning your Florence County vacation. From flights and accommodations, to rental cars and activities, we know how to create a travel experience like no other.

Top destinations in Florence County

A sunset over a forested landscape with a river and a parking lot.

Lake City

Lake City

The Latest Florence County Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Westgate Myrtle Beach Oceanfront Resort

Westgate Myrtle Beach Oceanfront Resort

Save 100% on your flight
$419
per person
Nov 7 - Nov 11
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Myrtle Beach (MYR)
8.6/10 Excellent! (1,337 reviews)
Marina Inn Grande Dunes Condos & Suites

Marina Inn Grande Dunes Condos & Suites

Save 100% on your flight
$1,292
per person
Oct 9 - Oct 17
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Myrtle Beach (MYR)
9.4/10 Exceptional! (192 reviews)
Marina Inn At Grande Dunes

Marina Inn At Grande Dunes

Save 100% on your flight
$1,255
per person
Oct 9 - Oct 17
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Myrtle Beach (MYR)
9.4/10 Exceptional! (1,812 reviews)
Best place to stay in Myrtle Beach!! Fantastic!

Reviewed on Aug 28, 2026

North Beach Resort & Villas

North Beach Resort & Villas

Windy Hill
Save 100% on your flight
$1,309
per person
Oct 9 - Oct 17
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Myrtle Beach (MYR)
8.8/10 Excellent! (1,083 reviews)
Compass Cove Resort

Compass Cove Resort

$987
per person
Oct 9 - Oct 17
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Myrtle Beach (MYR)
8/10 Very Good! (803 reviews)
Very good , clean ,, friendly

Reviewed on Aug 29, 2026

Find the Best Florence County Vacation Packages

Florence County Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Florence Regional Airport (FLO)
Top Sights
Palmetto Shores Lake, Columns Plantation and Florence Veterans Park

Florence County Hotel Deals

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC
Fully refundable
$80 nightly
$89 total
Sep 7 - Sep 8
Total with taxes and fees
9/10 Wonderful! (2,406 reviews)
"Clean, updated room. Comfortable bed. Free breakfast. Conveniently off interstate. Food options close/delivered."

Reviewed on Aug 29, 2026

Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$64 nightly
$71 total
Aug 30 - Aug 31
Total with taxes and fees
8.6/10 Excellent! (2,711 reviews)
"Everything was great"

Reviewed on Aug 28, 2026

Howard Johnson by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$88 nightly
$98 total
Sep 28 - Sep 29
Total with taxes and fees
Quality Inn & Suites Florence Civic Center
See all 353 properties in Florence County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Florence County attractions

A Florence Center building with a parking lot and a clear sky.

Florence Civic Center

8.0/10 (599 reviews)
After visiting Florence Civic Center, make a plan to see the other sights and activities in Florence. While in this family-friendly area, you can savor the top-notch restaurants.
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A shopping mall with a Magnolia Mall sign and a Burlington store across the street.

Magnolia Mall

8.2/10 (745 reviews)
You can enjoy retail therapy at Magnolia Mall during your visit to Florence. While in this trendy area, you can savor the top-notch restaurants.
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A modern building with large windows and a crosswalk at an intersection.

Florence County Museum

7.8/10 (236 reviews)
You can spend time browsing the exhibits at Florence County Museum in Florence. While in this relaxing area, you can savor the top-notch restaurants.
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A golf course with a clear sky, green grass, sand bunkers, and distant mountains.

The Traces Golf Club

7.6/10 (42 reviews)
Enjoy a round of golf in Florence at The Traces Golf Club. While in this family-friendly area, you can savor the top-notch restaurants.
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Eastern Carolina Agricultural Fairgrounds

7.4/10 (162 reviews)
Take the family on an outing to Eastern Carolina Agricultural Fairgrounds during your trip to Florence. While in this relaxing area, you can savor the top-notch restaurants.
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Florence Motor Speedway

7.2/10 (26 reviews)
Catch an event at Florence Motor Speedway during your trip to Timmonsville. While in this trendy area, you can savor the top-notch restaurants.
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Florence Veterans Park

8.0/10 (58 reviews)
Explore the great outdoors at Florence Veterans Park, a lovely green space in Florence. Check out the shops and top-notch restaurants in this family-friendly area.
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Dr. Eddie Floyd Tennis Center

Catch an event at Dr. Eddie Floyd Tennis Center during your trip to Florence. Check out the shops and top-notch restaurants in this family-friendly area.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.