Florence County Vacations & Trips from $462
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Your Florence County Vacation
Leave the planning up to us with a Florence County vacation package. With everything arranged before you leave home, the only thing left to do is sit back, chill out and enjoy this destination's countless delights. A trip to Florence County wouldn't be complete without getting to some of its best cities, starting with Florence. Two of the most popular attractions here include Magnolia Mall and Mcleod Regional Medical Center. Lake City is another favorite city with Florence County travelers. Visitors to this exciting destination enjoy The Country Club at Lake City and Moore Farms Botanical Garden. Expedia is a one-stop shop for planning your Florence County vacation. From flights and accommodations, to rental cars and activities, we know how to create a travel experience like no other.
Top destinations in Florence County
Lake City
The Latest Florence County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Willow Lodge
$758
per person
Dec 9 - Dec 13
found 19 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Myrtle Beach (MYR)
9.6/10 Exceptional! (853 reviews)
It's great place to stay for fishing or golfing especially. Plenty of parking and spots for smaller boats. Close to restaurants and a boat ramp.
Reviewed on Oct 12, 2026
Marina Inn At Grande Dunes
$811
per person
Dec 23 - Dec 27
found 5 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Myrtle Beach (MYR)
9.4/10 Exceptional! (1,853 reviews)
Great resort, exceeded my expectations, staff was great, room was wonderful, will definitely be back
Reviewed on Oct 12, 2026
Find the Best Florence County Vacation Packages
Florence County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Florence Regional Airport (FLO) |
Top Sights | Palmetto Shores Lake, Columns Plantation and Florence Veterans Park |
Florence County Hotel Deals
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
$100 total
Oct 18 - Oct 19
Total with taxes and fees
Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$65 nightly
$72 total
Oct 14 - Oct 15
Total with taxes and fees
8.6/10 Excellent! (2,737 reviews)
"Excellent hotel! Will stay again."
Reviewed on Oct 11, 2026
Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundable
$101 nightly
$113 total
Nov 3 - Nov 4
Total with taxes and fees
9/10 Wonderful! (1,371 reviews)
"The Comfort Inn in Florence SC was well a kept place to stay with professional service and a very nice breakfast set up. We were happy with the choice we made by staying at Comfort Inn in Florence SC."
Reviewed on Oct 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Florence County attractions
Florence Civic Center
8.0/10 (599 reviews)
After visiting Florence Civic Center, make a plan to see the other sights and activities in Florence. While in this family-friendly area, you can savor the top-notch restaurants.
Magnolia Mall
8.2/10 (745 reviews)
You can enjoy retail therapy at Magnolia Mall during your visit to Florence. While in this trendy area, you can savor the top-notch restaurants.
Florence County Museum
7.8/10 (236 reviews)
You can spend time browsing the exhibits at Florence County Museum in Florence. While in this trendy area, you can savor the top-notch restaurants.
The Traces Golf Club
7.6/10 (42 reviews)
Enjoy a round of golf in Florence at The Traces Golf Club. While in this trendy area, you can savor the top-notch restaurants.
Eastern Carolina Agricultural Fairgrounds
7.4/10 (162 reviews)
Take the family on an outing to Eastern Carolina Agricultural Fairgrounds during your trip to Florence. While in this trendy area, you can savor the top-notch restaurants.
Florence Motor Speedway
7.2/10 (26 reviews)
Catch an event at Florence Motor Speedway during your trip to Timmonsville. While in this relaxing area, you can savor the top-notch restaurants.
Dr. Eddie Floyd Tennis Center
Catch an event at Dr. Eddie Floyd Tennis Center during your trip to Florence. Check out the shops and top-notch restaurants in this family-friendly area.
Lions Park
7.6/10 (19 reviews)
Explore the great outdoors at Lions Park, a lovely green space in Lake City. Stroll along the area's lakeside or simply enjoy its restaurants.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
