Title: Top Florence County Hotels: 2026 Best Hotels in Florence County - Expedia.com [Vacation Rentals in Florence County](https://expedia.com/Destinations-In-Florence-County.d553248635976432658.Vacation-Rental-Destinations)[Florence County Flights](https://expedia.com/Destinations-In-Florence-County.d553248635976432658.Flight-Destinations)[Car Rentals in Florence County](https://expedia.com/Destinations-In-Florence-County.d553248635976432658.Car-Rental-Destinations)[Florence County Vacations](https://expedia.com/Florence-County.d553248635976432658.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Florence County ![Wyche Pavilion Greenville South Carolina ](https://images.trvl-media.com/place/1221/22638cec-95e4-4f53-af15-3963f8a47f19.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Florence [](https://expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels) ![a stunning aerial panoramic shot of the blue waters of Lake Hartwell surrounded by vast miles of lush green trees and grass with powerful clouds at sunset in Fair Play South Carolina USA](https://images.trvl-media.com/place/8506/47c9f422-933e-4135-8743-774b754f1db4.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Lake City [](https://expedia.com/Lake-City-Hotels.d8506.Travel-Guide-Hotels) ![The tree canopy walk is cool. If you don't like high places might not be for you and the bridges do bounce when you walk across to the next platform. It is beautiful with the river under you.](https://images.trvl-media.com/place/3000353109/1ba541e6-959a-412b-af08-d95ad3aaedb8.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Coward [](https://expedia.com/Coward-Hotels.d3000353109.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Feb 27 - Feb 28](https://www.expedia.com/Hotel-Search?regionId=553248635976432658&startDate=2026-02-27&endDate=2026-02-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 28 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=553248635976432658&startDate=2026-02-28&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=553248635976432658&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248635976432658&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Florence County hotels ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fefdad76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fad493a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a63ff680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) Florence 9.2/10 Wonderful (1,225 reviews) "The staff was friendly and the room was clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Camila $97 nightly $108 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0b9239a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC [](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) Florence 9.0/10 Wonderful (2,236 reviews) "Room was clean, staff friendly, and the includes breakfast was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha $86 nightly $96 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking (1st Floor) | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/f9691b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/e7174d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) Florence 8.6/10 Excellent (2,571 reviews) "I nice place to stay, very quiet, good breakfast, nice staff, spotless room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy $70 nightly $79 total Mar 4 - Mar 5 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/e08b1bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/de3f1188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/c76a36a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/7c55894f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Marriott Florence [](https://www.expedia.com/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) Florence 8.8/10 Excellent (518 reviews) "Clean room, great location, easy check-in & check-out, friendly service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shaun $107 nightly $120 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/e2ea309a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/0e00b7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown [](https://www.expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) Florence 9.0/10 Wonderful (1,000 reviews) "Great location and well maintained property. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $111 nightly $124 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/7f29240e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/f732d5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking (Deluxe Family Room) | Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/9ce36c42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/3c3cf86e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) Florence 7.8/10 Good (1,670 reviews) "Clean rooms, friendly staff, great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna $104 nightly $117 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Studio, Multiple Beds | Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/cd925f1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/ca4e1745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/63709e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Florence [](https://www.expedia.com/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) Florence 9.0/10 Wonderful (763 reviews) "Checking in was a breeze and the staff was excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany $105 nightly $118 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/5b7b6acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/20f68e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/8339db76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 [](https://www.expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) Florence 8.4/10 Very Good (1,001 reviews) "We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marita $101 nightly $113 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/852cfc33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dc8d999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/f82666ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center [](https://www.expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) Florence 7.8/10 Good (1,271 reviews) "Quiet clean and many options local for food etc Good for a night or two stay Bed was comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Louis $83 nightly $93 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/ddbd2495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/68010423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/f19c2d4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/825507c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Florence [](https://www.expedia.com/Florence-Hotels-Hilton-Garden-Inn-Florence.h1367205.Hotel-Information) Florence 8.6/10 Excellent (283 reviews) "The hotel is very pet friendly. Close to stores and restaurants. Clean, friendly, for is great in the restaurant in the hotel as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle $114 nightly $128 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hilton-Garden-Inn-Florence.h1367205.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/89338f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/042032ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/b2e2f539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/1aa3f791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Florence - Civic Center by IHG [](https://www.expedia.com/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) Florence 9.4/10 Exceptional (960 reviews) "Room clean, bed good, breakfast good choices, front desk excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mona $135 nightly $151 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/a3469465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed | Desk, iron/ironing board, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/w4000h2663x0y0-4c6e3b9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/a86309c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/44d17659.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Florence [](https://www.expedia.com/Florence-Hotels-Courtyard-By-Marriott-Florence.h84519.Hotel-Information) Florence 7.8/10 Good (713 reviews) "Very nice hotel. Clean, pleasant staff, and very well done room with comfortable bed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly $97 nightly $109 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Courtyard-By-Marriott-Florence.h84519.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/995e3ecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/59604fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/a2c60bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/3e9ccd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) Florence 9.0/10 Wonderful (871 reviews) "The employees were so nice!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ron $118 nightly $132 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/9c0353ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/fb5956cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/07b3e89f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/6c72c859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) Florence 9.2/10 Wonderful (1,001 reviews) "Clean rooms and nice breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adam $118 nightly $132 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/88f4ba4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/1e0c4eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/f287bfc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence Center [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) Florence 9.0/10 Wonderful (857 reviews) "Staff was very kind and conscious of our needs" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert $111 nightly $124 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Room, 1 Queen Bed, Accessible, Non Smoking | In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/73965d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/93db4fd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/2d26ec35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) Florence 6.8/10 (1,000 reviews) "Friendly staff, clean room, very comfortable bed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Willie $63 nightly $71 total Mar 2 - Mar 3 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Suite, 2 Double Beds | Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/bad3cc5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/ad99b77d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/5961e0c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/0d9737a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Florence [](https://www.expedia.com/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) Florence 8.6/10 Excellent (1,012 reviews) "Krystal was great!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James $97 nightly $109 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/25ce2409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/0dc87414.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/23e97d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | Living area | 42-inch LCD TV with cable channels, TV, MP3 dock](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/fc5c34c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Florence, SC [](https://www.expedia.com/Florence-Hotels-Home2-Suites-By-Hilton-Florence.h7271220.Hotel-Information) Florence 8.2/10 Very Good (1,000 reviews) "Everything was excellent!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara M $106 nightly $119 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Home2-Suites-By-Hilton-Florence.h7271220.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/86912dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/6cda2c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5a5d3612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Florence I-20 [](https://www.expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) Florence 9.2/10 Wonderful (589 reviews) "Friendly staff, clean and comfortable room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) craig $114 nightly $128 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/3ba2ede7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/1a4a47d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/d6de6ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence/I-95 North [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) Florence 6.8/10 (1,002 reviews) "Great room and reasonable price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hattab $63 nightly $71 total Feb 28 - Mar 1 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-13&endDate=2026-03-14®ionId=553248635976432658&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_553248635976432658) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Florence-County.d553248635976432658.Hotel-Destinations)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Florence-County.d553248635976432658.Hotel-Destinations) ## Top Florence County Hotel Reviews ![Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31_y.jpg) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG 10/10 Excellent "Great experience. Front desk was extremely nice when checking in. Breakfast was great and the rooms were very good size and very clean. " [](https://expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Clean new facility staff all friendly and room really as in the pics ;)" [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Residence Inn Marriott Florence](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb_y.jpg) ### Residence Inn Marriott Florence 10/10 Excellent "Room was clean and Ms. Angel at the front desk got me checked in quickly. The true queen on staff was MS. Cynthia she made breakfast feel like you were eating at your Aunties house. Will definitely be back next year!!!" [](https://expedia.com/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321_y.jpg) ### Hyatt Place Florence Downtown 10/10 Excellent "All was very good" [](https://expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc_y.jpg) ### Quality Inn & Suites Florence Civic Center 10/10 Excellent "Room was clean, staff very accommodating, breakfast was good. " [](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/17df73d5_y.jpg) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG 10/10 Excellent "Yes" [](https://expedia.com/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![Best Western Inn](https://images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf_y.jpg) ### Best Western Inn 10/10 Excellent "Clean well maintained Friendly Staff" [](https://expedia.com/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Hampton Inn & Suites Florence Center](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003_y.jpg) ### Hampton Inn & Suites Florence Center 10/10 Excellent "Staff was amazing, and rooms where so nice!" [](https://expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg) ### Hampton Inn & Suites Florence-North-I-95 10/10 Excellent "Everything was wonderful " [](https://expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ## Price trends for hotels in Florence County | Less expensive | More expensive | Next month | | -------------- | -------------- | ---------- | | November | January | $107 | | Month | Price | | --------- | ----- | | January | $111 | | February | $108 | | March | $107 | | April | $110 | | May | $108 | | June | $104 | | July | $103 | | August | $105 | | September | $110 | | October | $105 | | November | $102 | | December | $108 | Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Florence County. Select dates and complete search for nightly totals inclusive of taxes and fees. ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Florence County - [Florence Hotels ](https://expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels) - [Timmonsville Hotels ](https://expedia.com/Timmonsville-Hotels.d180880.Travel-Guide-Hotels) - [Effingham Hotels ](https://expedia.com/Effingham-Hotels.d553248635975849973.Travel-Guide-Hotels) - [Johnsonville Hotels ](https://expedia.com/Johnsonville-Hotels.d3000455987.Travel-Guide-Hotels) - [Scranton Hotels ](https://expedia.com/Scranton-Hotels.d3000456074.Travel-Guide-Hotels) - [Pamplico Hotels ](https://expedia.com/Pamplico-Hotels.d3000353197.Travel-Guide-Hotels) - [Coward Hotels ](https://expedia.com/Coward-Hotels.d3000353109.Travel-Guide-Hotels) - [Cartersville Hotels ](https://expedia.com/Cartersville-Hotels.d553248635975876193.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Florence Civic Center ](https://expedia.com/Florence-Civic-Center-Hotels.0-l6165605-0.Travel-Guide-Filter-Hotels) - [Hotels near Magnolia Mall ](https://expedia.com/Magnolia-Mall-Hotels.0-l6165602-0.Travel-Guide-Filter-Hotels) - [Hotels near Francis Marion University ](https://expedia.com/Francis-Marion-University-Hotels.0-l6162133-0.Travel-Guide-Filter-Hotels) - [Hotels near Mcleod Regional Medical Center ](https://expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Hotels near Eastern Carolina Agricultural Fairgrounds ](https://expedia.com/Eastern-Carolina-Agricultural-Fairgrounds-Hotels.0-l6162140-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Motor Speedway ](https://expedia.com/Florence-Motor-Speedway-Hotels.0-l6215468-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Museum ](https://expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence National Cemetery ](https://expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Oakdale Country Club ](https://expedia.com/Oakdale-Country-Club-Hotels.0-l553248621532657334-0.Travel-Guide-Filter-Hotels) - [Hotels near The Country Club at Lake City ](https://expedia.com/The-Country-Club-At-Lake-City-Hotels.0-l553248621560871593-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Florence County - [Vacation Homes in Florence County ](https://expedia.com/Florence-County-Private-Vacation-Homes.d553248635976432658-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Condo Rentals in Florence County ](https://expedia.com/Florence-County-Condos.d553248635976432658-aaCondos.Travel-Guide-Accommodation) - [Apartments in Florence County ](https://expedia.com/Florence-County-Apartments.d553248635976432658-aaApartments.Travel-Guide-Accommodation) - [Motels in Florence County ](https://expedia.com/Florence-County-Motels.d553248635976432658-aaMotels.Travel-Guide-Accommodation) - [Cottages in Florence County ](https://expedia.com/Florence-County-Cottages.d553248635976432658-aaCottages.Travel-Guide-Accommodation) - [Cabin Rentals in Florence County ](https://expedia.com/Florence-County-Cabins.d553248635976432658-aaCabins.Travel-Guide-Accommodation) - [B&B in Florence County ](https://expedia.com/Florence-County-Bed-And-Breakfast.d553248635976432658-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Farmstay in Florence County ](https://expedia.com/Florence-County-Agritourism.d553248635976432658-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Florence County ](https://expedia.com/Florence-County-Apart-Hotels.d553248635976432658-aaApartHotels.Travel-Guide-Accommodation) - [RV Parks in Florence County ](https://expedia.com/Florence-County-RV-Parks.d553248635976432658-aaRVParks.Travel-Guide-Accommodation) - [Guest Houses in Florence County ](https://expedia.com/Florence-County-Guest-Houses.d553248635976432658-aaGuestHouses.Travel-Guide-Accommodation) ### Hotels near Florence County Airports - [Myrtle Beach Intl. Airport Hotels ](https://expedia.com/Myrtle-Beach-Intl-Airport-Hotels.0-aMYR-0.Travel-Guide-Filter-Hotels) - [Florence Regional Airport Hotels ](https://expedia.com/Florence-Regional-Airport-Hotels.0-aFLO-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Comfort Inn & Suites Florence Center Area ](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) - [Park Inn by Radisson Florence, SC ](https://expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) - [Howard Johnson by Wyndham Florence ](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) - [Hyatt Place Florence Downtown ](https://expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) - [TownePlace Suites by Marriott Florence ](https://expedia.com/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) - [La Quinta Inn & Suites by Wyndham Florence ](https://expedia.com/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) - [Residence Inn Marriott Florence ](https://expedia.com/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) - [Microtel Inn & Suites by Wyndham Florence ](https://expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) - [Hampton Inn & Suites Florence Center ](https://expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) - [Quality Inn & Suites Florence Civic Center ](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) [See a list of all hotels in Florence County](https://expedia.com/All-Florence-County-Hotels.d553248635976432658.Travel-Guide-City-All-Hotels) ### Expedia's Latest Trends Hotels - [Charleston Historic District Luxury Hotels](https://expedia.com/Charleston-Historic-District-Charleston-Hotels-Luxury-Hotel.0-n6057948-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Hotels in Downtown Charleston](https://expedia.com/Downtown-Charleston-Charleston-Hotels.0-n553248633938969537-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Spartanburg County](https://expedia.com/Destinations-In-Spartanburg-County-Luxury-Hotel.0-0-d553248635976433422-tLuxuryHotel.Hotel-Filter-Destinations) - [Fort Jackson hotels](https://expedia.com/Fort-Jackson-Hotels.0-l6145263-0.Travel-Guide-Filter-Hotels) - [Hotels in Greenville County](https://expedia.com/Destinations-In-Greenville-County.d553248635976432805.Hotel-Destinations) - [Hotels in Downtown Columbia](https://expedia.com/Downtown-Columbia-Columbia-Hotels.0-n553248634698384142-0.Travel-Guide-Filter-Hotels) - [Hotels in French Quarter](https://expedia.com/French-Quarter-Charleston-Hotels.0-n3000663061-0.Travel-Guide-Filter-Hotels) - [Broadway at the Beach hotels](https://expedia.com/Broadway-At-The-Beach-Hotels.0-l6079959-0.Travel-Guide-Filter-Hotels) - [Hotels in Greenville Downtown](https://expedia.com/Greenville-Downtown-Greenville-Hotels.0-n6348006-0.Travel-Guide-Filter-Hotels) - [Clemson University hotels](https://expedia.com/Clemson-University-Hotels.0-l6127431-0.Travel-Guide-Filter-Hotels) - [Hotels in Charleston Historic District](https://expedia.com/Charleston-Historic-District-Charleston-Hotels.0-n6057948-0.Travel-Guide-Filter-Hotels) - [Cherry Grove Beach Oceanfront Hotels](https://expedia.com/Cherry-Grove-Beach-North-Myrtle-Beach-Hotels-Oceanfront-Hotels.0-n553248621561867974-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-friendly Hotels in Charleston County](https://expedia.com/Destinations-In-Charleston-County-Pet-Friendly-Hotel.0-0-d553248635083907096-tPetfriendlyHotel.Hotel-Filter-Destinations) - [Hotels in Colleton County](https://expedia.com/Destinations-In-Colleton-County.d553248635976433901.Hotel-Destinations) Flights - [Flights from Union County](https://expedia.com/lp/flights/553248635976432651/flights-from-union-county) Cars - [compact Car Rentals in Charleston County](https://expedia.com/Compact-Car-Rentals-In-Charleston-County.d553248635083907096-tCompact.Car-Rental-Destination-Class) - [Car rental North Charleston Airport (CHS)](https://expedia.com/Car-Rentals-In-Charleston-Intl.d5457987.Car-Rental-Guide) - [Car rental West Columbia Airport (CAE)](https://expedia.com/Car-Rentals-In-Columbia-Metropolitan.d4538691.Car-Rental-Guide) - [Car rental Myrtle Beach Airport (MYR)](https://expedia.com/Car-Rentals-In-Myrtle-Beach-Intl.d5396813.Car-Rental-Guide) - [Car rental Greer Airport (GSP)](https://expedia.com/Car-Rentals-In-Greenville-Spartanburg-Intl.d5264199.Car-Rental-Guide) Activities - [Things to do in Anderson County](https://expedia.com/Things-To-Do-In-Anderson-County.d553248635996998401.Travel-Guide-Activities) Packages - [Charleston Historic District Vacation Packages](https://expedia.com/Charleston-Historic-District.d6057948.Destination-Travel-Guides) - [Fred W. Symmes Chapel](https://expedia.com/Fred-W-Symmes-Chapel-Cleveland.d553248621532656718.Vacation-Attraction) - [Family Kingdom Amusement Park](https://expedia.com/Family-Kingdom-Amusement-Park-Myrtle-Beach.d6079999.Vacation-Attraction) - [Ripley's Aquarium](https://expedia.com/Ripleys-Aquarium-Myrtle-Beach.d6079963.Vacation-Attraction) General - [Visit Charleston Historic District](https://expedia.com/Charleston-Charleston-Historic-District.dx6057948) - [Visit French Quarter](https://expedia.com/Charleston-French-Quarter.dx3000663061) - [Visit Horry County](https://expedia.com/Horry-County.dx553248635083907335) - [Visit South of the Border](https://expedia.com/Hamer-South-Of-The-Border.dx3000456123) - [Visit Downtown Myrtle Beach](https://expedia.com/Myrtle-Beach-Downtown-Myrtle-Beach.dx553248633938969374) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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