Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Grand Cayman Independent Hotels

See all 350 Hotels in Grand Cayman
Margaritaville Beach Resort Grand Cayman

Margaritaville Beach Resort Grand Cayman

269 West Bay Road, Sunset Cove, Seven Mile Beach
    3.5 out of 5.0
     
     
    3.7 out of 5 (164 reviews)
    Comfortable,clean, energetic, relaxing environment Great accomodations for extended stay at good price point.....clean rooms, fun energetic lobby and … - 

    Margaritaville Beach Resort Grand Cayman$262

    Margaritaville Beach Resort Grand Cayman$262
    Grand Caymanian Resort

    Grand Caymanian Resort

    278 Crighton Drive, Crystal Harbour
      3.5 out of 5.0
       
       
      4.1 out of 5 (91 reviews)
      Nice pool, great rooms and excellent food in the restaurant. Best price to stay on the island. A li … - 

      Grand Caymanian Resort$122

      Grand Caymanian Resort$122
      Morritts Tortuga Club

      Morritts Tortuga Club

      2289 Queens Highway, Grand Cayman, East End
        3.5 out of 5.0
         
         
        4.0 out of 5 (44 reviews)
        GREAT PLACE FOR A SCUBA DIVER AS WELL Dive shop is right in the hotel. We booked here because we have a time share the next day that we h … - 

        Morritts Tortuga Club$189

        Morritts Tortuga Club$189
        Regal Beach Club

        Regal Beach Club

        431 West Bay Road, Seven Mile Beach
          4.0 out of 5.0
           
           
          4.8 out of 5 (20 reviews)
          We thoroughly enjoyed our stay! The Regal Beach Club condos are excellent. Large, great grounds, and every balcony has a view of th … - 
          Villas of the Galleon

          Villas of the Galleon

          West Bay Road, Seven Mile Beach
            3.0 out of 5.0
             
             
            4.8 out of 5 (21 reviews)
            Beautiful and peaceful. Well situated and the beach was absolutely amazing. - 

            Villas of the Galleon$340

            Villas of the Galleon$340
            Compass Point Dive Resort

            Compass Point Dive Resort

            346 Austin Conolly Drive, East End
              3.5 out of 5.0
               
               
              4.8 out of 5 (139 reviews)
              VACATION DELIGHT Excellent Location on East End of Grand Cayman. Stayed at this Resort last year so my husband could … - 
              Eldemire's Tropical Island Inn

              Eldemire's Tropical Island Inn

              18 Pebbles Way, George Town
                3.0 out of 5.0
                 
                 
                4.0 out of 5 (65 reviews)
                Very quiet, and to relax around the pool with a drink after playing hard in the water and on island … - 
                Shangri-La Boutique Bed & Breakfast

                Shangri-La Boutique Bed & Breakfast

                29 Sticky Toffee Lane, West Bay
                  4.0 out of 5.0
                   
                   
                  5.0 out of 5 (61 reviews)
                  Lovely B&B with easy access to Cemetery Beach We stayed for 3 nights and enjoyed meeting international guests for breakfast on the patio, lovely … - 

                  Shangri-La Boutique Bed & Breakfast$140

                  Shangri-La Boutique Bed & Breakfast$140
                  Seven Mile Beach Resort & Club

                  Seven Mile Beach Resort & Club

                  19 D Piper Way, West Bay Road, Seven Mile Beach
                    3.0 out of 5.0
                     
                     
                    4.3 out of 5 (90 reviews)
                    Home away from home This place has it all kitchen living space two bedrooms with two baths. Pool jacuzzi and only two m … - 

                    Seven Mile Beach Resort & Club$225

                    Seven Mile Beach Resort & Club$225
                    Wyndham Reef Resort All - Inclusive

                    Wyndham Reef Resort All - Inclusive

                    2221 Queens Highway Colliers Bay, East End
                      3.5 out of 5.0
                       
                       
                      4.0 out of 5 (7 reviews)
                      Beautiful, quiet location with amazing staff There are so many places to choose from when booking on the Cayman Islands, and we wanted something … - 
                      Seven Mile Beach Condo - Sunset Cove - 1st Floor

                      Seven Mile Beach Condo - Sunset Cove - 1st Floor

                      , George Town
                         
                         
                        Silver Sands Condominiums

                        Silver Sands Condominiums

                        2131 West Bay Road, Seven Mile Beach
                          4.0 out of 5.0
                           
                           
                          5.0 out of 5 (2 reviews)
                          Beautiful and relaxing The setting for these condos is so picturesque, my photos looks like post cards! The beach is absol … - 
                          Grand Cayman Oceanfront Condo, Serenity Kai, Kaibo Yacht Club

                          Grand Cayman Oceanfront Condo, Serenity Kai, Kaibo Yacht Club

                          , Cayman Kai
                             
                             
                            4.8 out of 5 (8 reviews)
                            White Sands # 9- A Romantic Condo on a Flawless Beach

                            White Sands # 9- A Romantic Condo on a Flawless Beach

                            , Seven Mile Beach
                               
                               
                              5.0 out of 5 (1 reviews)
                              Calypso Cove #1 "diver's Cave"

                              Calypso Cove #1 "diver's Cave"

                              , west bay
                                 
                                 
                                5.0 out of 5 (3 reviews)
                                Calypso Cove #4 "texas Gate"

                                Calypso Cove #4 "texas Gate"

                                , West Bay
                                   
                                   
                                  5.0 out of 5 (2 reviews)
                                  World Famous Seven Mile Beach "location, Cayman Islands" Welcome to Paradise

                                  World Famous Seven Mile Beach "location, Cayman Islands" Welcome to Paradise

                                  , George Town
                                     
                                     
                                    4.9 out of 5 (27 reviews)
                                    Regal Beach Club #631- At the Centre of Everything on Seven Mile Beach

                                    Regal Beach Club #631- At the Centre of Everything on Seven Mile Beach

                                    , Seven Mile Beach
                                       
                                       
                                      'three Little Birds' 2+br Spectacular Views, Private Beach

                                      'three Little Birds' 2+br Spectacular Views, Private Beach

                                      , Grand Cayman
                                         
                                         
                                        5.0 out of 5 (16 reviews)
                                        Royal Heighta Villa - 3 Bd/ 2 Bath

                                        Royal Heighta Villa - 3 Bd/ 2 Bath

                                        , Bodden Town
                                           
                                           
                                          5.0 out of 5 (4 reviews)

                                          Recently booked Grand Cayman hotels

                                          Sunshine Suites Resort
                                          3.5 out of 5.0
                                          Last booking: 3 hours ago
                                          Holiday Inn Resort Grand Cayman
                                          3.5 out of 5.0
                                          Last booking: 14 hours ago
                                          Wyndham Reef Resort
                                          3.5 out of 5.0
                                          Last booking: 14 hours ago
                                          Comfort Suites Seven Mile Beach
                                          3.5 out of 5.0
                                          Last booking: 33 hours ago

                                          Independent Grand Cayman Hotel Guide

                                          Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Grand Cayman, Cayman Islands. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Grand Cayman hotels guarantees an unparalleled level of comfort and quality.

                                          You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Grand Cayman Independent locations may even offer extra little benefits and discounts for frequent travelers.