Greenville Downtown Vacations from $401

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Your Greenville Downtown Vacation

A favorite residential neighborhood, Greenville Downtown lures visitors with its festivals, culture and dining. Lock in a vacation package to Greenville Downtown and discover all of that and more. Not sure what to do and see during your trip to Greenville Downtown? Nearby attractions such as Falls Park on the Reedy, Bon Secours Wellness Arena and The Peace Center are good places to begin. Whatever your dream Greenville Downtown vacation may look like, you can make it a reality with Expedia.

The Latest Greenville Downtown Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Landing Apartments - Lyman
Liberty Hall Bed and Breakfast
Hotel Hartness
Zoka - Modern Mountain Retreat
Grand Bohemian Lodge Greenville, Autograph Collection

Where to stay in Greenville Downtown

Find the best Greenville Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Greenville Downtown

Greenville Downtown Hotel Deals

Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $172 total per night from Aug 9 to Aug 10
$172 total
Aug 9 - Aug 10
Total with taxes and fees
8.8/10 Excellent! (1,003 reviews)
"Nice location within walking distance to many restaurants and shopping. Clean room. Some construction in the lobby area."

Reviewed on Jul 26, 2026

Hyatt Regency Greenville
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$361 nightly
The price is $396 total per night from Aug 18 to Aug 19
$396 total
Aug 18 - Aug 19
Total with taxes and fees
9.6/10 Exceptional! (535 reviews)
"This is the very best hotel in South Carolina. Extremely kind and helpful staff, thanks especially to the valets, beautiful art and surroundings, comfortable rooms with great light and linens."

Reviewed on Jul 28, 2026

Grand Bohemian Lodge Greenville, Autograph Collection
Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown

3 out of 5
128 East Broad Street Greenville SC
$139 nightly
The price is $153 total per night from Aug 9 to Aug 10
$153 total
Aug 9 - Aug 10
Total with taxes and fees
9.2/10 Wonderful! (1,006 reviews)
"Spacious room, good location. Elevators were slow and once not working for a day. But overall the stay was nice."

Reviewed on Jul 28, 2026

Hyatt Place Greenville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Greenville Downtown attractions

Things to do

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.