Guayaquil Vacations & Trips from $252

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Your Guayaquil Vacation

Make organizing your next big adventure quick and easy with a Guayaquil vacation package. Whether it's the history, cuisine or something else that draws you to this destination, our packages will help you experience the best of it. Putting together an itinerary for your trip to Guayaquil? Begin with top cities like Puerto Santa Ana, Posorja and Pocitos. Expedia is your one-stop shop for planning your Guayaquil vacation. From flights and hotels, to rental cars and more, we're here to help you curate a travel experience like no other.

Top destinations in Guayaquil

A curved pathway lined with palm trees and colorful plants, leading to a hill with colorful buildings.

Guayaquil

Guayaquil

The Latest Guayaquil Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Mansión Alcázar Boutique Hotel

Mansión Alcázar Boutique Hotel

Downtown Cuenca
$252
per person
Nov 14 - Nov 16
found 21 hours ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
9.6/10 Exceptional! (390 reviews)
Beautiful hotel in a great location. Excellent breakfast included.

Reviewed on Oct 10, 2026

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

Las Peñas
Save 100% on your flight
$2,433
per person
Nov 20 - Nov 30
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Guayaquil (GYE)
10/10 Exceptional! (5 reviews)
Hotel Ramada

Hotel Ramada

Downtown Guayaquil
$893
per person
Nov 20 - Nov 30
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Guayaquil (GYE)
8/10 Very Good! (414 reviews)
Como siempre me atienden super bien

Reviewed on Oct 9, 2026

Hotel del Parque

Hotel del Parque

Save 100% on your flight
$1,945
per person
Nov 21 - Nov 30
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Guayaquil (GYE)
9.8/10 Exceptional! (138 reviews)
La propiedad es increible la seguridad el staff del hotel 10/10 las instalaciones de primera recomendado 100%

Reviewed on Oct 8, 2026

Hotel Boutique Santa Lucia

Hotel Boutique Santa Lucia

Downtown Cuenca
$827
per person
Dec 3 - Dec 7
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE)
9.2/10 Wonderful! (409 reviews)

Find the Best Guayaquil Vacation Packages

Guayaquil Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

Guayaquil Hotel Deals

Hilton Colon Guayaquil

Hilton Colon Guayaquil

Av Francisco de Orellana Mz 111 Guayaquil
Fully refundableReserve now, pay when you stay
$98 nightly
$110 total
Nov 15 - Nov 16
8.8/10 Excellent! (1,002 reviews)
"I made the reservation 30 minutes before my arrival through a 3rd party and everything went smoothly. Room was clean and The staff was very professional."

Reviewed on Oct 14, 2026

Hilton Colon Guayaquil
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$100 nightly
$112 total
Oct 30 - Oct 31
9.4/10 Exceptional! (1,004 reviews)
"Love staying at this hotel!"

Reviewed on Oct 15, 2026

Wyndham Guayaquil Puerto Santa Ana
Oro Verde Guayaquil

Oro Verde Guayaquil

9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$85 nightly
$96 total
Nov 13 - Nov 14
Oro Verde Guayaquil
See all 405 properties in Guayaquil
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Guayaquil attractions

A curved pathway lined with palm trees and colorful flowers, leading to a hilltop with colorful buildings.

Malecon 2000

9.2/10 (1,617 reviews)
Malecon 2000 is just one of the places to see in Guayaquil, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.
See properties
A monitor lizard on a sandy beach with a clear blue ocean in the background.

Varadero Beach

8.8/10 (11 reviews)
Why not spend a carefree afternoon at Varadero Beach during your travels in Posorja?
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A tall ship docked at a waterfront promenade with modern buildings and palm trees in the background.

City Mall

9.0/10 (534 reviews)
During your visit to Guayaquil, you can do some window-shopping at City Mall. Visit the area's cathedral, or simply enjoy its seafood restaurants.
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Mall del Sol Shopping Center

9.2/10 (1,163 reviews)
During your visit to Guayaquil, you can find the perfect gifts to bring home at Mall del Sol Shopping Center. Visit the area's cathedral, or simply enjoy its seafood restaurants.
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Mall del Sur

8.8/10 (272 reviews)
You can enjoy retail therapy at Mall del Sur during your visit to Guayaquil. While in this walkable area, find time to visit its shops.
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Guayaquil Convention Center

8.8/10 (282 reviews)
Learn about the events happening at Guayaquil Convention Center during your trip to Guayaquil. While you're in the area, find time to visit its shops.
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San Marino Mall

9.0/10 (560 reviews)
During your visit to Guayaquil, you can find the perfect gifts to bring home at San Marino Mall. Visit the area's cathedral, or simply enjoy its seafood restaurants.
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Banco Pichincha Monumental Stadium

8.4/10 (192 reviews)
Catch an event at Banco Pichincha Monumental Stadium during your trip to Guayaquil. While you're in the area, find time to visit its shops.
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What to do in Guayaquil

City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

$65
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

$122
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
Cocoa farm and Chocolate making!

Cocoa farm and Chocolate making!

$155
per adult
Cocoa farm and Chocolate making!
See all activities in Guayaquil
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