Guayaquil Vacations & Trips from $259

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Your Guayaquil Vacation

Make organizing your next big adventure quick and easy with a Guayaquil vacation package. Whether it's the history, cuisine or something else that draws you to this destination, our packages will help you experience the best of it. Putting together an itinerary for your trip to Guayaquil? Begin with top cities like Puerto Santa Ana, Posorja and Pocitos. Expedia is your one-stop shop for planning your Guayaquil vacation. From flights and hotels, to rental cars and more, we're here to help you curate a travel experience like no other.

Top destinations in Guayaquil

A curved pathway lined with palm trees and colorful plants, leading to a hill with colorful buildings.

Guayaquil

Guayaquil

The Latest Guayaquil Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Boutique Santa Lucia

Hotel Boutique Santa Lucia

Downtown Cuenca
$259
per person
Jan 6 - Jan 8
found 14 hours ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
9.2/10 Wonderful! (409 reviews)
Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

Las Peñas
$908
per person
Jan 11 - Jan 13
found 20 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE)
10/10 Exceptional! (5 reviews)
Oro Verde Manta

Oro Verde Manta

Save 100% on your flight
$724
per person
Dec 23 - Dec 30
found 1 day ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
9.2/10 Wonderful! (789 reviews)
La atención fue excelente de principio a fin. El desayuno delicioso, tenían muchas opciones de desayuno. Lo que más me gustó fue el encocado de camarón y mi esposo amó los mini croissants calientitos. Encontramos la habitación súper limpia y todos los días que me nos hospedamos fueron a limpiarla. Estamos seguros que volveremos a hospedarnos en Hotel Oro Verde Manta. Quedamos muy satisfechos!!

Reviewed on Oct 19, 2026

Hotel Perla Spondylus

Hotel Perla Spondylus

Centro de Manta
$408
per person
Dec 23 - Dec 30
found 21 hours ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
9/10 Wonderful! (67 reviews)
Me gusto la piscina. Ademas, tienen parqueadero propio.

Reviewed on Oct 12, 2026

Mantahost Hotel

Mantahost Hotel

Barbasquillo
Save 100% on your flight
$1,079
per person
Dec 23 - Dec 30
found 21 hours ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
8.6/10 Excellent! (323 reviews)

Find the Best Guayaquil Vacation Packages

Guayaquil Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

Guayaquil Hotel Deals

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$100 nightly
$112 total
Nov 8 - Nov 9
Wyndham Guayaquil Puerto Santa Ana
Hilton Colon Guayaquil

Hilton Colon Guayaquil

Av Francisco de Orellana Mz 111 Guayaquil
Fully refundableReserve now, pay when you stay
$100 nightly
$113 total
Nov 1 - Nov 2
8.8/10 Excellent! (1,004 reviews)
"Upon check in, front desk wanted to charge me $65 for the second adult. I told them the reservation was made for two adults. They said it wasn’t. Only when I showed them the reservation email they said it was ok. I was assigned an accessible room. Not what I requested. Closet floor had lots of dust ..."

Reviewed on Oct 20, 2026

Hilton Colon Guayaquil
Oro Verde Guayaquil

Oro Verde Guayaquil

9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$85 nightly
$96 total
Nov 13 - Nov 14
Oro Verde Guayaquil
See all 406 properties in Guayaquil
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Guayaquil attractions

A monitor lizard on a sandy beach with a clear blue ocean in the background.

Varadero Beach

8.8/10 (11 reviews)
Why not spend a carefree afternoon at Varadero Beach during your travels in Posorja?
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A curved pathway lined with palm trees and colorful flowers, leading to a hilltop with colorful buildings.

Malecon 2000

9.2/10 (1,617 reviews)
Malecon 2000 is just one of the places to see in Guayaquil, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.
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Mall del Sol Shopping Center

9.2/10 (1,163 reviews)
During your visit to Guayaquil, you can find the perfect gifts to bring home at Mall del Sol Shopping Center. Visit the area's cathedral, or simply enjoy its seafood restaurants.
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Mall del Sur

8.8/10 (272 reviews)
You can enjoy retail therapy at Mall del Sur during your visit to Guayaquil. While in this walkable area, find time to visit its shops.
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Guayaquil Convention Center

8.8/10 (282 reviews)
Learn about the events happening at Guayaquil Convention Center during your trip to Guayaquil. While you're in the area, find time to visit its shops.
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San Marino Mall

9.0/10 (560 reviews)
During your visit to Guayaquil, you can find the perfect gifts to bring home at San Marino Mall. Visit the area's cathedral, or simply enjoy its seafood restaurants.
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Banco Pichincha Monumental Stadium

8.4/10 (192 reviews)
Catch an event at Banco Pichincha Monumental Stadium during your trip to Guayaquil. While you're in the area, find time to visit its shops.
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Riocentro Los Ceibos

9.4/10 (53 reviews)
During your visit to San Eduardo, you can enjoy retail therapy at Riocentro Los Ceibos. Visit the area's cathedral, or simply enjoy its seafood restaurants.
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What to do in Guayaquil

City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

$65
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

$122
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
Cocoa farm and Chocolate making!

Cocoa farm and Chocolate making!

$155
per adult
Cocoa farm and Chocolate making!
See all activities in Guayaquil
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.