Guayaquil Vacations & Trips from $353

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Your Guayaquil Vacation

Make organizing your next big adventure quick and easy with a Guayaquil vacation package. Whether it's the history, cuisine or something else that draws you to this destination, our packages will help you experience the best of it. Putting together an itinerary for your trip to Guayaquil? Begin with top cities like Puerto Santa Ana, Posorja and Pocitos. Expedia is your one-stop shop for planning your Guayaquil vacation. From flights and hotels, to rental cars and more, we're here to help you curate a travel experience like no other.

Top destinations in Guayaquil

A curved pathway lined with palm trees and colorful plants, leading to a hill with colorful buildings.

Guayaquil

Guayaquil

The Latest Guayaquil Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Mar Azul

Hotel Mar Azul

$353
per person
Dec 26 - Dec 31
found 1 day ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
9/10 Wonderful! (86 reviews)
Helpful host and cafe in the hotel a plus…

Reviewed on Sep 5, 2026

Oro Verde Manta

Oro Verde Manta

Save 100% on your flight
$632
per person
Dec 26 - Dec 31
found 1 day ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
9.2/10 Wonderful! (789 reviews)
Hotel Cruz del Vado by Art Hotels Ecuador

Hotel Cruz del Vado by Art Hotels Ecuador

$1,771
per person
Dec 15 - Dec 27
found 1 day ago
Roundtrip flight included
New York (JFK) to Guayaquil (GYE)
9.4/10 Exceptional! (45 reviews)
Everything was great. Unfortunately I didn’t check but most of the rooms are windowless. As I’m claustrophobic this was issue. The other thing if you are coming by car is the parking which is about half a block away. These are common themes for hotels in the historic center though. If you are looking for traditional American comfort try hotels on the other side of town

Reviewed on Oct 11, 2026

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

Las Peñas
$1,111
per person
Nov 19 - Nov 22
found 17 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Guayaquil (GYE)
10/10 Exceptional! (5 reviews)
Hospedaje Casa Aida Victoria

Hospedaje Casa Aida Victoria

Downtown Cuenca
Save 100% on your flight
$55,998
per person
Dec 15 - Dec 27
found 1 day ago
Roundtrip flight included
New York (JFK) to Guayaquil (GYE)
No reviews

Find the Best Guayaquil Vacation Packages

Guayaquil Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

Guayaquil Hotel Deals

Hilton Colon Guayaquil

Hilton Colon Guayaquil

Av Francisco de Orellana Mz 111 Guayaquil
Fully refundableReserve now, pay when you stay
$98 nightly
$110 total
Nov 1 - Nov 2
8.8/10 Excellent! (1,001 reviews)
"Most places would offer refills if you bought a cup of coffee at close to 5 USD, however this place, they give you like a 6 oz cup and no refills.. A bit overpriced."

Reviewed on Oct 10, 2026

Hilton Colon Guayaquil
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$105 nightly
$118 total
Nov 8 - Nov 9
9.4/10 Exceptional! (1,001 reviews)
"Estaba perfecto un lugar confortable el desayuno perfecto delicioso"

Reviewed on Oct 11, 2026

Wyndham Guayaquil Puerto Santa Ana
Oro Verde Guayaquil

Oro Verde Guayaquil

9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$94 nightly
$106 total
Oct 18 - Oct 19
9.6/10 Exceptional! (1,005 reviews)
"My #1 choice of staying in Guayaquil."

Reviewed on Oct 12, 2026

Oro Verde Guayaquil
See all 405 properties in Guayaquil
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Guayaquil attractions

A curved pathway lined with palm trees and colorful flowers, leading to a hilltop with colorful buildings.

Malecon 2000

9.2/10 (1,617 reviews)
Malecon 2000 is just one of the places to see in Guayaquil, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.
See properties
A monitor lizard on a sandy beach with a clear blue ocean in the background.

Varadero Beach

8.8/10 (11 reviews)
Why not spend a carefree afternoon at Varadero Beach during your travels in Posorja?
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A tall ship docked at a waterfront promenade with modern buildings and palm trees in the background.

City Mall

9.0/10 (534 reviews)
During your visit to Guayaquil, you can do some window-shopping at City Mall. Visit the area's cathedral, or simply enjoy its seafood restaurants.
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Mall del Sol Shopping Center

9.2/10 (1,163 reviews)
During your visit to Guayaquil, you can find the perfect gifts to bring home at Mall del Sol Shopping Center. Visit the area's cathedral, or simply enjoy its seafood restaurants.
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Mall del Sur

8.8/10 (272 reviews)
You can enjoy retail therapy at Mall del Sur during your visit to Guayaquil. While in this walkable area, find time to visit its shops.
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Guayaquil Convention Center

8.8/10 (282 reviews)
Learn about the events happening at Guayaquil Convention Center during your trip to Guayaquil. While you're in the area, find time to visit its shops.
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San Marino Mall

9.0/10 (560 reviews)
During your visit to Guayaquil, you can find the perfect gifts to bring home at San Marino Mall. Visit the area's cathedral, or simply enjoy its seafood restaurants.
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Banco Pichincha Monumental Stadium

8.4/10 (192 reviews)
Catch an event at Banco Pichincha Monumental Stadium during your trip to Guayaquil. While you're in the area, find time to visit its shops.
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What to do in Guayaquil

City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

$65
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

$122
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
Cocoa farm and Chocolate making!

Cocoa farm and Chocolate making!

$155
per adult
Cocoa farm and Chocolate making!
See all activities in Guayaquil
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