It's no coincidence that the word "muse" is in "museum!" Guillermo Spratling Museum aims to inspire and educate its visitors, so find a place for it on your itinerary.
It won't take you very long to find out why this museum is a hit with travelers to Centro. Pay the admission fee and then take your time to explore it. If you're eager for more sightseeing, Teleferico de Montetaxco, Santa Prisca Cathedral and Guerrero Park aren't very far from Guillermo Spratling Museum.