
Guymon Vacations from $512
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Your Guymon Vacation
From its rural countryside to its rich history and friendly locals, you'll find countless great reasons to spend time in the arid city of Guymon. Experience all this and more when you lock in your vacation package to Guymon. Guymon Community Theater, North Ridge Shopping Center and Thompson Park are just some of the many attractions worth exploring during your trip to Guymon. Your Guymon vacation is just clicks away. Explore airfares, hotels and more on Expedia for a getaway that's tailored to suit your style.
The Latest Guymon vacation packages
Price found within the past 48 hours. Click for updated prices.

The Cactus Cove Inn and Suites
Price was $547, price is now $512 per person
$512
per person
Aug 7 - Aug 9
found 1 day ago
Roundtrip non-stop flight included
Des Moines (DSM) to Amarillo (AMA)
8/10 Very Good! (2,487 reviews)
We didn’t realize this was an event type of hotel. If I had children that I wanted to have run around in an enclosed safe space, maybe I would have liked it better. We were also over the bar and the live music paly d until midnight.
Reviewed on Jun 24, 2026

The Big Texan Motel
Price was $604, price is now $560 per person
$560
per person
Aug 7 - Aug 9
found 1 day ago
Roundtrip non-stop flight included
Des Moines (DSM) to Amarillo (AMA)
9/10 Wonderful! (4,165 reviews)
I liked how close it is to the restaurant and highway. The rooms were clean, but loud at night with vehicles coming and going. Not the hotels fault! We would stay and eat here again.
Reviewed on Jun 26, 2026

La Quinta Inn & Suites by Wyndham Amarillo Airport
Price was $594, price is now $554 per person
$554
per person
Aug 7 - Aug 9
found 1 day ago
Roundtrip non-stop flight included
Des Moines (DSM) to Amarillo (AMA)
9.2/10 Wonderful! (1,006 reviews)
We stayed here for a wedding and enjoyed our stay. Rom was clean, service was great. Lobby well maintained and new looking furniture, high top sitting area with charging plugs. Quick drive to everything, Buc-ees right across the highway, restaurants, etc. Not really walkable to anything, as you're on a very busy access road with a field in between you and everything else. Breakfast was ok, but it's standard hotel breakfast so no surprises there. The only issue was there is no shelf in the shower and not really anywhere to hang a towel but on the shower itself. Big shower that replaced tub like many others have done, but just a small soap dish, so no room for shampoo, razors, etc. We pulled the small chair table into the bathroom, but you shouldn't have to do that. Not a big deal, but every other hotel I've stayed in has that now for the most part.
Reviewed on Jun 8, 2026

The Big Texan - Cabins & Wagons
Price was $739, price is now $693 per person
$693
per person
Aug 7 - Aug 9
found 1 day ago
Roundtrip non-stop flight included
Des Moines (DSM) to Amarillo (AMA)
9/10 Wonderful! (155 reviews)
Great place to stay. Cabins were clean. Front desk staff wasn’t the friendliest but not overly mean. I’m used to friendly people in Texas but maybe they were having a bad day or live in New Mexico. I’d definitely stay again even though they just have van that takes you to the restaurant, not a limo like advertised. Maybe it’s an Amarillo Limo??
Reviewed on Jun 16, 2026

Best Western Santa Fe
Price was $553, price is now $521 per person
$521
per person
Aug 7 - Aug 9
found 1 day ago
Roundtrip non-stop flight included
Des Moines (DSM) to Amarillo (AMA)
9/10 Wonderful! (1,017 reviews)
Decent place to spend night while making an overnight stop over. Rooms all updated. Interior renovation not long ago however the outside is a little crummy. Located in more of an industrial side of town but good restaurants close by and Buc-ees few miles away. Rate was very affordable. Would stay here again if just passing through.
Reviewed on Jun 25, 2026
Stay near popular Guymon attractions
Guymon Hotel Deals

Simple Rewards Inn
1201 E Highway 54 Guymon OK
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $63 total per night from Jul 1 to Jul 2
$63 total
Jul 1 - Jul 2
Total with taxes and fees
9/10 Wonderful! (1,000 reviews)
"Exceptionally courteous staff. Super clean. Breakfast was good and well organized. Stay here without hesitation. Best motel on our five day road trip across country"
Reviewed on Jun 24, 2026

Golden Mesa Casino and Hotel
2469 Mile 28 Rd Guymon OK
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $105 total per night from Jun 28 to Jun 29
$105 total
Jun 28 - Jun 29
Total with taxes and fees
10/10 Exceptional! (22 reviews)
"I had an excellent stay at Golden Mesa Casino & Hotel. My room was modern, spotless, and very comfortable, making it easy to relax after a long day. The entire property was exceptionally well maintained and had a welcoming atmosphere. What stood out the most was the outstanding customer service. ..."
Reviewed on Jun 25, 2026

Best Western Plus Guymon Hotel & Suites
1102 NE 6th Street Guymon OK
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $113 total per night from Jun 27 to Jun 28
$113 total
Jun 27 - Jun 28
Total with taxes and fees
9/10 Wonderful! (799 reviews)
"It’s my half way mark and I like staying the night here."
Reviewed on Jun 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Guymon Vacation Packages
Guymon Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Population | 11,900 |
Max Temp Winter | 50ºF |
Max Temp Summer | 95ºF |
Top Sights | Guymon Community Theater, Thompson Park and Wild Horse Gallery |
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