Title: Top 10 Hotels in Isla Santa María from $40 - Competitive Prices | Expedia.com [Vacation Rentals in Isla Santa María](https://expedia.com/Isla-Santa-Maria-Vacation-Rentals.d739209696364867584.Travel-Guide-VacationRentals)[Car Rentals in Isla Santa María](https://expedia.com/Car-Rentals-In-Isla-Santa-Maria.d739209696364867584.Car-Rental-Guide)[Isla Santa María Vacation Packages](https://expedia.com/Isla-Santa-Maria.d739209696364867584.Destination-Travel-Guides) ![Sea lions soaking in some rays on the island of espanola in the Galapagos. Unfortunately no mai tai's on this beach. #LifeAtExpedia #nature](https://images.trvl-media.com/place/739209696364867584/329f8833-28e7-41c2-a4af-1e9e3462ce94.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Delen Wong ![](https://images.trvl-media.com/place/739209696364867584/329f8833-28e7-41c2-a4af-1e9e3462ce94.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Isla Santa María Ocean view [](https://www.expedia.com/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=OCEAN_VIEW) Pool [](https://www.expedia.com/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=POOL) Family friendly [](https://www.expedia.com/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&travelerType=family_friendly) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=HOT_TUB) Spa [](https://www.expedia.com/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=SPA_ON_SITE) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=PETS) Apart hotel [](https://www.expedia.com/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&lodging=APART_HOTEL) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&lodging=APARTMENT) ## Check prices for these dates Tonight [Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=739209696364867584&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 7 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=739209696364867584&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=739209696364867584&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=739209696364867584&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Isla Santa María hotels ![Interior](https://images.trvl-media.com/lodging/123000000/122700000/122698200/122698173/37ab94a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/123000000/122700000/122698200/122698173/002f622f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Double or Twin Room | Down comforters, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/123000000/122700000/122698200/122698173/c7251e4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/123000000/122700000/122698200/122698173/e38fa236_edited_95c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### PENGUIN HOSTEL [](https://www.expedia.com/Puerto-Ayora-Hotels-Penguin.h122698173.Hotel-Information) Puerto Ayora 10/10 Exceptional (2 reviews) "Love the stay, very welcoming atmosphere, wonderful owners, I recommend this to everyone" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LEO $49 nightly $49 total Feb 7 - Feb 8 [](https://www.expedia.com/Puerto-Ayora-Hotels-Penguin.h122698173.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119080000/119077900/119077847/1d8b2799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Single Room | Laptop workspace, free WiFi](https://images.trvl-media.com/lodging/120000000/119080000/119077900/119077847/480813f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast](https://images.trvl-media.com/lodging/120000000/119080000/119077900/119077847/8c5ad5bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119080000/119077900/119077847/33a00204.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ECO HOSTAL ISLA AZUL [](https://www.expedia.com/Puerto-Ayora-Hotels-ECO-HOSTAL-ISLA-AZUL.h119077847.Hotel-Information) Puerto Ayora 10/10 Exceptional (2 reviews) "Loved that they had purified water to refill your water bottle instead of buying plastic! Staff were incredibly kind. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jaclyn $178 nightly $178 total Feb 7 - Feb 8 [](https://www.expedia.com/Puerto-Ayora-Hotels-ECO-HOSTAL-ISLA-AZUL.h119077847.Hotel-Information) ![Breakfast, dinner served; local and international cuisine, ocean views ](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/f2307f3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Duplex | View from room](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/5dea777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double or Twin Room | View from room](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/f92aa86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/a685ce77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ikala Galapagos Hotel [](https://www.expedia.com/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) Puerto Ayora 9.6/10 Exceptional (131 reviews) "Gorgeous property and wonderful staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robyn $221 nightly $243 total Feb 9 - Feb 10 [](https://www.expedia.com/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/0a441130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food court](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/3a29c8f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/467dc8d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, Terrace | View from room](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/62a98993.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cucuve [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information) Puerto Ayora 9.8/10 Exceptional (274 reviews) "Wonderful staff, beautiful room, delicious breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley $191 nightly $211 total Feb 7 - Feb 8 [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/92acdc7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/a854801f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/f83773fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine, ocean views ](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/1d2d0c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blu Galapagos Sustainable Waterfront Lodge [](https://www.expedia.com/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) Puerto Ayora 8.8/10 Excellent (125 reviews) "Beautiful property " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) David $250 nightly $275 total Feb 12 - Feb 13 [](https://www.expedia.com/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4890000/4884900/4884897/2f892016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/5000000/4890000/4884900/4884897/102ca9ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 1 Queen Bed, Ocean View | Premium bedding, in-room safe, individually decorated, desk](https://images.trvl-media.com/lodging/5000000/4890000/4884900/4884897/4c34b960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine, beach views ](https://images.trvl-media.com/lodging/5000000/4890000/4884900/4884897/6183fbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Angermeyer Waterfront Inn [](https://www.expedia.com/Puerto-Ayora-Hotels-Angermeyer-Waterfront-Inn.h4884897.Hotel-Information) Puerto Ayora 9.4/10 Exceptional (129 reviews) "Very clean room, great staff and excellent location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tomasz $244 nightly $268 total Feb 15 - Feb 16 [](https://www.expedia.com/Puerto-Ayora-Hotels-Angermeyer-Waterfront-Inn.h4884897.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/15000000/14660000/14658100/14658017/9110f771.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/15000000/14660000/14658100/14658017/6bab7837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/15000000/14660000/14658100/14658017/f181106b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/15000000/14660000/14658100/14658017/4e8a4e60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel La Casa de Judy [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-La-Casa-De-Judy.h14658017.Hotel-Information) Puerto Ayora 9.0/10 Wonderful (165 reviews) "We received an upgrade on the room with an ocean view. The room was clean, the staff friendly, breakfast was good, and the place is convenient to a laundry place and the downtown as well as the Darwin research center. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heidi $110 nightly $110 total Mar 7 - Mar 8 [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-La-Casa-De-Judy.h14658017.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/62b50762.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Double Room | Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/w2236h1687x0y0-81876455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/926c680e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/9ffdbf3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Finch Bay Galapagos Hotel [](https://www.expedia.com/Puerto-Ayora-Hotels-Finch-Bay-Galapagos-Hotel.h1862515.Hotel-Information) Puerto Ayora 9.2/10 Wonderful (92 reviews) "Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan $508 nightly $568 total Feb 25 - Feb 26 [](https://www.expedia.com/Puerto-Ayora-Hotels-Finch-Bay-Galapagos-Hotel.h1862515.Hotel-Information) ![Standard Triple Room | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/2ca19af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/64e7ee10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/d088e7ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | Bathroom | Shower, free toiletries, hair dryer, slippers](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/e94fe441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capitan Max B&B [](https://www.expedia.com/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) Puerto Ayora 9.8/10 Exceptional (210 reviews) "Clean , friendly staff, accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna $77 nightly $77 total Mar 6 - Mar 7 [](https://www.expedia.com/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/9ff6c70e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, Bay View | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/50b125ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/b352825f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, Bay View | Exterior](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/3d626fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Barranco Galapagos [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-Barranco-Galapagos.h111508035.Hotel-Information) Puerto Ayora 9.6/10 Exceptional (39 reviews) "Very comfortable hotel with good service and nice staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jairo $186 nightly $186 total Feb 24 - Feb 25 [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-Barranco-Galapagos.h111508035.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/39000000/38820000/38819900/38819899/f1f7ec0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/39000000/38820000/38819900/38819899/ee8ad519.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38820000/38819900/38819899/9c613ed1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38820000/38819900/38819899/4dcb74cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mainao [](https://www.expedia.com/Puerto-Ayora-Hotels-Mainao.h38819899.Hotel-Information) Puerto Ayora 9.6/10 Exceptional (34 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pavel $138 nightly $152 total Mar 7 - Mar 8 [](https://www.expedia.com/Puerto-Ayora-Hotels-Mainao.h38819899.Hotel-Information) ![Water view](https://images.trvl-media.com/lodging/15000000/14850000/14842500/14842408/e0f99a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/15000000/14850000/14842500/14842408/fa27162b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/15000000/14850000/14842500/14842408/9f35d995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/15000000/14850000/14842500/14842408/9e8c486e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Twin Hotel Galapagos [](https://www.expedia.com/Puerto-Ayora-Hotels-Twin-Hotel-Galapagos-By-Rotamundos.h14842408.Hotel-Information) Bella Vista 8.4/10 Very Good (45 reviews) "This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Chelsea $92 nightly $92 total Mar 7 - Mar 8 [](https://www.expedia.com/Puerto-Ayora-Hotels-Twin-Hotel-Galapagos-By-Rotamundos.h14842408.Hotel-Information) ![Jetted tub](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/19a51296.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/c4595842.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/d6476f6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/bb93ee14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Fiesta [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information) Puerto Ayora 9.0/10 Wonderful (389 reviews) "Perfect place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol $155 nightly $155 total Feb 9 - Feb 10 [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/96c0ae07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/f0b03fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/7136b5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pingüinos | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/f685f5c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Maidith Galapagos Inn [](https://www.expedia.com/Puerto-Ayora-Hotels-Maidith-Galapagos-Inn.h88474681.Hotel-Information) Puerto Ayora 10/10 Exceptional (110 reviews) "Overall excellent choice for a family stay in Puerto Ayora. Rooms are very clean and spacious and short walk to main ferry pier and lots of restaurants and shopping. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron $126 nightly $126 total Feb 16 - Feb 17 [](https://www.expedia.com/Puerto-Ayora-Hotels-Maidith-Galapagos-Inn.h88474681.Hotel-Information) ![Family Suite | Balcony view](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/e7fb3ff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/da8f2af7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/6302d135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/70b1e5e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Posada del Mar [](https://www.expedia.com/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information) Puerto Ayora 9.8/10 Exceptional (217 reviews) "This place is amazing, I only came across the lounge and kitchen on the higher floor on my second day but by far the best room during my trip" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharath $70 nightly $70 total Feb 8 - Feb 9 [](https://www.expedia.com/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information) ![Beach nearby, white sand](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/bf30a401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 2 Double Beds | Premium bedding, minibar, individually furnished, bed sheets](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/21a46bf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/a4592fb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/08740a7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Ninfa [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information) Puerto Ayora 8.4/10 Very Good (223 reviews) "Great, clean, and convenient place. Good location close to docks. Walkable to the Main Street. Hotel rooms clean with good service and breakfast. We stayed here two seperate times during Galapagos and would stay again. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Aly $158 nightly $158 total Feb 7 - Feb 8 [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90030000/90029600/90029511/27a5429e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Double Room | In-room safe, blackout drapes, bed sheets](https://images.trvl-media.com/lodging/91000000/90030000/90029600/90029511/ba2b8217.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90030000/90029600/90029511/6de76ce4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/91000000/90030000/90029600/90029511/c8e59971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fernandina Hotel & Spa Galápagos [](https://www.expedia.com/Puerto-Ayora-Hotels-HOTEL-FERNANDINA.h90029511.Hotel-Information) Puerto Ayora 9.4/10 Exceptional (32 reviews) "Great staff! Cute room and pool/hot tub" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew $113 nightly $113 total Feb 7 - Feb 8 [](https://www.expedia.com/Puerto-Ayora-Hotels-HOTEL-FERNANDINA.h90029511.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/55000000/54130000/54122700/54122610/6b409832.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/55000000/54130000/54122700/54122610/0a225066.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, bed sheets](https://images.trvl-media.com/lodging/55000000/54130000/54122700/54122610/7ca801a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/55000000/54130000/54122700/54122610/9e20aa1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Leon Marino Galapagos [](https://www.expedia.com/Puerto-Ayora-Hotels-Grand-Hotel-Lobo-Marino-Galapagos.h54122610.Hotel-Information) Puerto Ayora 8.8/10 Excellent (15 reviews) "Staff was very friendly and location convenient. Modern interior." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Marc $92 nightly $92 total Feb 7 - Feb 8 [](https://www.expedia.com/Puerto-Ayora-Hotels-Grand-Hotel-Lobo-Marino-Galapagos.h54122610.Hotel-Information) ![Standard Double or Twin Room, 1 Bedroom | Free minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/10000000/9800000/9794800/9794727/faf80253.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/10000000/9800000/9794800/9794727/f4f162b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/10000000/9800000/9794800/9794727/f34c4f73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Free minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/10000000/9800000/9794800/9794727/a21927f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Santa Fe [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-Santa-Fe.h9794727.Hotel-Information) Puerto Ayora 9.6/10 Exceptional (14 reviews) "Beautiful hotel, with amazing staff, and great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven $194 nightly $213 total Feb 7 - Feb 8 [](https://www.expedia.com/Puerto-Ayora-Hotels-Hotel-Santa-Fe.h9794727.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/92000000/91760000/91753200/91753116/b9fd0c52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91760000/91753200/91753116/8c7674f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/92000000/91760000/91753200/91753116/0e46886e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living room](https://images.trvl-media.com/lodging/92000000/91760000/91753200/91753116/3e5d5308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Acacia Galapagos Boutique Hotel [](https://www.expedia.com/Puerto-Ayora-Hotels-Acacia-Galapagos-Boutique-Hotel.h91753116.Hotel-Information) Puerto Ayora 9.8/10 Exceptional (27 reviews) "Beautiful boutique hotel with wonderful staff who attended to our every need. Breakfast was made fresh to order every morning- yogurt, fruit, granola, and then the main dish which was always eggs, a breakfast meat and some side dishes which changed daily. The entire hotel was spotless. Daily housekeeping kept our room spotless as well. Mini split air conditioning in our room kept us cool and comfortable. Many thanks for a wonderful stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael $243 nightly $243 total Feb 14 - Feb 15 [](https://www.expedia.com/Puerto-Ayora-Hotels-Acacia-Galapagos-Boutique-Hotel.h91753116.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21®ionId=739209696364867584&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FIsla-Santa-Maria-Hotels.d739209696364867584.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FIsla-Santa-Maria-Hotels.d739209696364867584.Travel-Guide-Hotels) ## Stay near popular Isla Santa María attractions ![Swimming with sea turtles was one of the many amazing moments of my Galapagos adventure. Like most of the other animals, they went about their business without seeming to even notice the people around. ](https://images.trvl-media.com/place/553248621554455070/325aa0d2-97cf-4c55-9857-ef170ef86bb3.jpg) Photo by Tove Martin ### Post Office Bay Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621554455070) ![Bedtime in the Galapagos #golden](https://images.trvl-media.com/place/553248621554455077/3a418a9c-4b02-498b-ba03-95c819b8b8f2.jpg) Photo by Delen Wong ### Punta Suarez Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621554455077) ## Learn more about Isla Santa María Head to sights like Galápagos National Park and Post Office Bay as you discover Isla Santa María. [See all hotels in Isla Santa María](https://www.expedia.com/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21&adults=2®ionId=739209696364867584) ![Sea lions soaking in some rays on the island of espanola in the Galapagos. Unfortunately no mai tai's on this beach. #LifeAtExpedia #nature](https://images.trvl-media.com/place/739209696364867584/329f8833-28e7-41c2-a4af-1e9e3462ce94.jpg?impolicy=fcrop&w=900&h=437&p=1&q=high) Photo by Delen Wong ## Top Isla Santa María Hotel Reviews ![Hotel el descanso del Guia](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/b6171efd_y.jpg) ### Hotel el descanso del Guia 10/10 Excellent "Beautiful room. Comfortable balcony. Wonderful staff. Fresh breakfast. Very clean hotel. " [](https://expedia.com/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information) ![Hotel Ninfa](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/08eca00e_y.jpg) ### Hotel Ninfa 10/10 Excellent "Clean room, great staff. Would be nice if there was an airport shuttle instead of putting us all on separate $30 taxis. Myself and five other guests all had separate taxis to get to the same ferry. " [](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information) ![Fernandina Hotel & Spa Galápagos](https://images.trvl-media.com/lodging/91000000/90030000/90029600/90029511/27a5429e_y.jpg) ### Fernandina Hotel & Spa Galápagos 10/10 Excellent "Great staff! Cute room and pool/hot tub" [](https://expedia.com/Puerto-Ayora-Hotels-HOTEL-FERNANDINA.h90029511.Hotel-Information) ![Blu Galapagos Sustainable Waterfront Lodge](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/92acdc7e_y.jpg) ### Blu Galapagos Sustainable Waterfront Lodge 10/10 Excellent "Great room with amazing view. Incredible service " [](https://expedia.com/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) ![Hotel Cucuve](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/733c9cb5_y.jpg) ### Hotel Cucuve 10/10 Excellent "Very, very clean. The staff was exceptional. Great amenities- left water bottles for guests, one free drink per day, had a patio for guests to use by the water. Breakfast was a lot of variety. Would give a 10 pot of 10!!" [](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information) ![Capitan Max B&B](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48_y.jpg) ### Capitan Max B&B 10/10 Excellent "Max and his staff were amazing! So very polite and helpful with everything. The room was super clean, everyday! The food was simple for breakfast but also tasted amazing. Can’t say enough nice things about this place. I would highly recommend it to anyone look for a place to stay in Santa Cruz. " [](https://expedia.com/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) ![Galapagos Dreams](https://images.trvl-media.com/lodging/12000000/11700000/11698100/11698055/6897639d_y.jpg) ### Galapagos Dreams 10/10 Excellent "The entire staff was very friendly and helpful. Breakfast was good with hot coffee always on. The location was walking distance to tourist spots in town from the pier to Darwin’s research center. I booked my tours through Galapagos Dreams and Joatan worked up a personalized tour for me. This made my stay easier as the staff kept me informed of pick up times and activities. Overall it really made my stay very enjoyable. " [](https://expedia.com/Puerto-Ayora-Hotels-GALAPAGOS-DREAMS.h11698055.Hotel-Information) ![Ikala Galapagos Hotel](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/ecbf00ed_y.jpg) ### Ikala Galapagos Hotel 10/10 Excellent "Gorgeous property and wonderful staff!" [](https://expedia.com/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) ![Posada del Mar](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/e7fb3ff1_y.jpg) ### Posada del Mar 10/10 Excellent "Fantastic room - spacious and all the amenities. Amazing staff, very friendly and helped with bags. Great location, very close to main shops, and quiet at night. Would definitely stay here again." [](https://expedia.com/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information) ## More cheap stays in Isla Santa María ![White House Galapagos](https://images.trvl-media.com/lodging/16000000/15570000/15568900/15568830/c16ecd66_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### White House Galapagos Calle Roberto Schiess e Isla Duncan Puerto Ayora Santa Cruz $40 nightly $40 total Mar 4 - Mar 5 8.8/10 Excellent! (99 reviews) [](https://expedia.com/Puerto-Ayora-Hotels-WHITE-HOUSE-GALAPAGOS.h15568830.Hotel-Information) ![Hostal Casa Cascada](https://images.trvl-media.com/lodging/117000000/116770000/116762700/116762676/fccb146c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hostal Casa Cascada Pje. 1 Puerto Ayora Galápagos Islands $47 nightly $47 total Feb 22 - Feb 23 9.6/10 Exceptional! (4 reviews) [](https://expedia.com/Puerto-Ayora-Hotels-Hostal-Casa-Cascada.h116762676.Hotel-Information) ![Hostal Sir Francis Drake](https://images.trvl-media.com/lodging/17000000/16170000/16164100/16164081/b9484033_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hostal Sir Francis Drake Av. Baltra y Charles Binford Puerto Ayora Galapagos $70 nightly $70 total Feb 19 - Feb 20 7.4/10 Good! (74 reviews) [](https://expedia.com/Puerto-Ayora-Hotels-Hostal-Sir-Francis-Drake.h16164081.Hotel-Information) ![El Barranco Galapagos](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/910f927d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### El Barranco Galapagos Los colonos Puerto Ayora Galapagos $186 nightly $186 total Feb 24 - Feb 25 9.6/10 Exceptional! (39 reviews) [](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Barranco-Galapagos.h111508035.Hotel-Information) ![Acacia Galapagos Boutique Hotel](https://images.trvl-media.com/lodging/92000000/91760000/91753200/91753116/8c7674f6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Acacia Galapagos Boutique Hotel C/ Floreana Y Matazarnos Puerto Ayora Islas Galápagos $243 nightly $243 total Feb 14 - Feb 15 9.8/10 Exceptional! (27 reviews) [](https://expedia.com/Puerto-Ayora-Hotels-Acacia-Galapagos-Boutique-Hotel.h91753116.Hotel-Information) ![Hotel Brisas Del Pacifico](https://images.trvl-media.com/lodging/17000000/16390000/16387800/16387791/f2a55546_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Brisas Del Pacifico General Rodriguez Puerto Ayora [Get rates](https://expedia.com/Hotel-Search?startDate=2%2F20%2F2026&endDate=2%2F21%2F2026&selected=16387791&PinnedHotelID=16387791&HadPinnedHotel=true®ionId=739209696364867584) 7.4/10 Good! (80 reviews) [](https://expedia.com/Puerto-Ayora-Hotels-HOTEL-BRISAS-DEL-PACIFICO.h16387791.Hotel-Information) ## Frequently asked questions ### Where is the best place for a stay in Isla Santa María? ### What are some of the best vacation rentals that Isla Santa María has to offer? ### If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund? ### Where can I learn more about changing or cancelling my trip to Isla Santa María? ### What is staying in Isla Santa María like? ### What should I see while I'm in Isla Santa María? ### What's the weather like in Isla Santa María? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app