Title: Visit Isla Santa María: 2026 Travel Guide for Isla Santa María, Galápagos | Expedia.com [Hotels in Isla Santa María](https://expedia.com/Isla-Santa-Maria-Hotels.d739209696364867584.Travel-Guide-Hotels)[Vacation Rentals in Isla Santa María](https://expedia.com/Isla-Santa-Maria-Vacation-Rentals.d739209696364867584.Travel-Guide-VacationRentals)[Car Rentals in Isla Santa María](https://expedia.com/Car-Rentals-In-Isla-Santa-Maria.d739209696364867584.Car-Rental-Guide)[Isla Santa María Vacation Packages](https://expedia.com/Isla-Santa-Maria.d739209696364867584.Destination-Travel-Guides) # Isla Santa María ## Travel Guide ![I've been spotted! A family of marine iguanas auditioning for meerkat manor #LifeAtExpedia ](https://images.trvl-media.com/place/553248621554455077/bde266be-4597-4eee-abb2-e62a70f719e4.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Bedtime in the Galapagos #golden](https://images.trvl-media.com/place/553248621554455077/3a418a9c-4b02-498b-ba03-95c819b8b8f2.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Sea lions soaking in some rays on the island of espanola in the Galapagos. Unfortunately no mai tai's on this beach. #LifeAtExpedia #nature](https://images.trvl-media.com/place/739209696364867584/329f8833-28e7-41c2-a4af-1e9e3462ce94.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Heaven is a place on earth #galapagosislands #galapagos #ecuador #bucketlist #lifeatexpedia #blue](https://images.trvl-media.com/place/739209696364867584/288a46a5-b2f1-4749-983e-16420e663562.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![The red-footed booby. El Barranco, also known as Prince Phillip's steps, on Genovesa Island are carved into the rocks of a steep cliff from the ocean leading up to a huge plateau full of millions of birds. #Galapagos Islands, Equador. #NationalPark](https://images.trvl-media.com/place/739209696364867584/ec198bf5-ccce-422b-bf14-8d892c734338.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Isla Santa María Things to do - Isla Santa María Hotel Deals - Vacation Rentals in Isla Santa María ![Hotel Fiesta](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/19a51296_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Fiesta Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos $155 nightly $155 total Mar 20 - Mar 21 Stay at this hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Las ... [](https://expedia.com/Hotel-Search?startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&selected=9690626&PinnedHotelID=9690626&HadPinnedHotel=true®ionId=739209696364867584) ![Maidith Galapagos Inn](https://images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/96c0ae07_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Maidith Galapagos Inn Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos $115 nightly $115 total Apr 2 - Apr 3 Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful ... 9.8/10 Exceptional! (120 reviews) Very helpful staff. The water in the room was very convenient. Reviewed on Mar 16, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F2%2F2026&endDate=4%2F3%2F2026&selected=88474681&PinnedHotelID=88474681&HadPinnedHotel=true®ionId=739209696364867584) ![Hotel el descanso del Guia](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/48310af4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel el descanso del Guia Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos $95 nightly $95 total Apr 19 - Apr 20 Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our ... 8.8/10 Excellent! (193 reviews) The staff was amazing, so attentive and kind! Reviewed on Feb 25, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F19%2F2026&endDate=4%2F20%2F2026&selected=17525206&PinnedHotelID=17525206&HadPinnedHotel=true®ionId=739209696364867584) [See all 211 properties in Isla Santa María](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F20%2F2026&endDate=3%2F21%2F2026®ionId=739209696364867584) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Torre Mar Galapagos Boutique Suites](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/ffb9bce3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Torre Mar Galapagos Boutique Suites San Cristobal y General Rodriguez Lara Puerto Ayora Stay at this aparthotel in Puerto Ayora. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Fishing Piers and Las Ninfas Lagoon ... 9.2/10 Wonderful! (20 reviews) Place was spotless! Very accommodating and helpful staff. Reviewed on Mar 1, 2026 [](https://expedia.com/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Boutique-Suites.h16786878.Hotel-Information) ![Galapagos and Beyond](https://images.trvl-media.com/lodging/100000000/99530000/99523000/99522986/0516fdcd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Galapagos and Beyond Indefatigable entre Duncan & Juan Puerto Ayora Galapagos Book a stay at this luxury condo in Puerto Ayora. Enjoy free breakfast, free WiFi, and hot springs on site. Popular attractions Fishing Piers and Gus Angermeyer ... 10/10 Exceptional! (13 reviews) Spacious, Convenient, and Accommodating We spent 5 nights in a 3-bedroom condo apartment as a family of 4, including 2 teenagers. The condo was the perfect base from which we explored the Galapagos with a series of day trips. Breakfast was included every morning to get us started for each day of ... Reviewed on Mar 8, 2026 [](https://expedia.com/Puerto-Ayora-Hotels-Galapagos-And-Beyond.h99522986.Hotel-Information) ![Del mar del Galapagos ](https://images.trvl-media.com/lodging/112000000/111130000/111128800/111128727/398af5f3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Del mar del Galapagos calle cucuve Puerto Ayora Islas Galápagos Stay at this apartment in Puerto Ayora. Enjoy free WiFi and climate control. Popular attractions Fishing Piers and Gus Angermeyer Ferry Terminal are located ... [](https://expedia.com/Puerto-Ayora-Hotels-Del-Mar-Del-Galapagos.h111128727.Hotel-Information) [See all properties in Isla Santa María](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=739209696364867584&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Isla Santa María hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=739209696364867584&startDate=2026-03-19&endDate=2026-03-20)[Mar 19 - Mar 20](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=739209696364867584&startDate=2026-03-19&endDate=2026-03-20) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=739209696364867584&startDate=2026-03-20&endDate=2026-03-21)[Mar 20 - Mar 21](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=739209696364867584&startDate=2026-03-20&endDate=2026-03-21) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=739209696364867584&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)[Mar 20 - Mar 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=739209696364867584&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=739209696364867584&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=739209696364867584&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) ### Popular places to visit ![I've been spotted! A family of marine iguanas auditioning for meerkat manor #LifeAtExpedia ](https://images.trvl-media.com/place/553248621554455077/bde266be-4597-4eee-abb2-e62a70f719e4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Punta Suarez Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area. [](https://expedia.com/Punta-Suarez-Isla-Santa-Maria.d553248621554455077.Vacation-Attraction) ![Swimming with sea turtles was one of the many amazing moments of my Galapagos adventure. Like most of the other animals, they went about their business without seeming to even notice the people around. ](https://images.trvl-media.com/place/553248621554455070/325aa0d2-97cf-4c55-9857-ef170ef86bb3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Post Office Bay Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting. [](https://expedia.com/Post-Office-Bay-Isla-Santa-Maria.d553248621554455070.Vacation-Attraction) ### Things to do ![Learn about the history of Floreana](https://mediaim.expedia.com/localexpert/2135051/55a75ae9-35ca-4e2d-b76e-0226916a1374.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Full Day Floreana Tour $220 per adult [](https://expedia.com/things-to-do/full-day-floreana-tour.a2135051.activity-details) ![Galapagos Enchanting 3 Islands](https://mediaim.expedia.com/localexpert/2311367/cc73c8d2-cc66-485b-a99a-e1ebbc553293.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Galapagos Enchanting 3 Islands (5 Days) $1,349 per adult [](https://expedia.com/things-to-do/galapagos-enchanting-3-islands-5-days.a2311367.activity-details) ![Faune seeing at the snorkeling](https://mediaim.expedia.com/localexpert/2135374/574fafeb-77d8-4a24-b445-c1796320d30f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Full Day Santa Fe Playa escondida snorkeling tour $220 per adult [](https://expedia.com/things-to-do/full-day-santa-fe-playa-escondida-snorkeling-tour.a2135374.activity-details) [See all activities in Isla Santa María](https://expedia.com/Things-To-Do-In-Isla-Santa-Maria.d739209696364867584.Travel-Guide-Activities) - Cities near Isla Santa María - Places of interest [Puerto Velasco Ibarra](https://expedia.com/Puerto-Velasco-Ibarra.dx6359210) - [Post Office Bay ](https://expedia.com/Post-Office-Bay-Isla-Santa-Maria.d553248621554455070.Vacation-Attraction) - [Punta Suarez ](https://expedia.com/Punta-Suarez-Isla-Santa-Maria.d553248621554455077.Vacation-Attraction) - [Galápagos National Park ](https://expedia.com/Galapagos-National-Park-Galapagos.d6112453.Vacation-Attraction) - [Tortuga Bay Beach ](https://expedia.com/Tortuga-Bay-Beach-Bella-Vista.d6171324.Vacation-Attraction) - [Charles Darwin Research Station ](https://expedia.com/Charles-Darwin-Research-Station-Galapagos.d6171312.Vacation-Attraction) - [Playa de los Alemanes ](https://expedia.com/Playa-De-Los-Alemanes-Puerto-Ayora.d553248625325955800.Vacation-Attraction) - [Academy Bay ](https://expedia.com/Academy-Bay-Galapagos.d3000006066.Vacation-Attraction) - [Malecon ](https://expedia.com/Malecon-Puerto-Ayora.d553248634304917070.Vacation-Attraction) - [Las Grietas ](https://expedia.com/Las-Grietas-Bella-Vista.d6166619.Vacation-Attraction) - [El Garrapatero Beach ](https://expedia.com/El-Garrapatero-Beach-Bella-Vista.d6222374.Vacation-Attraction) - [Las Ninfas Lagoon ](https://expedia.com/Las-Ninfas-Lagoon-Puerto-Ayora.d794682581167067136.Vacation-Attraction) - [South Plaza Island ](https://expedia.com/South-Plaza-Island-Galapagos.d6336661.Vacation-Attraction) - [Fishing Piers ](https://expedia.com/Fishing-Piers-Puerto-Ayora.d688667559214501888.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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