Large rocks and a sandy beach with sparse vegetation.

Isla Santa María Vacation Rentals

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Our top choices for Isla Santa María vacation rentals

1. Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (24 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
$153 nightly
The price is $153
Sep 3 - Sep 4
Modern apartment with 18 feet ceilings and private terrace with view to a park

2. Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (27 reviews)
"The host was so nice, kind, and friendly."
United States
Maho
$131 nightly
The price is $131
Sep 8 - Sep 9
Torre Mar Galapagos Boutique Suites

3. Suites

Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (24 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
$71 nightly
The price is $71
Sep 3 - Sep 4
Suites

4. Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
$96 nightly
The price is $96
Sep 3 - Sep 4
Villa Galapagos

5. Colmena Apartment in downtown Puerto Ayora, Santa Cruz

Colmena Apartment in downtown Puerto Ayora, Santa Cruz
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We had an excellent experience at Five minutes from the malecon Santa Cruz - Puerto Ayora. The property is brand new, very secure, and perfectly located. What truly made our stay special was our host, Gaby. She was always available, attentive, and ready to help us with anything we needed. Had we known about this place earlier, we would have booked it for our entire stay in Santa Cruz. We highly recommend this accommodation to anyone visiting the island — it’s a gem!"
United States
jacques
$157 nightly
The price is $178
Sep 5 - Sep 6
Colmena Apartment in downtown Puerto Ayora, Santa Cruz

6. Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
2.0 out of 10, (1 review)
"Beware of this scam, the owner did not receive our reservstion nor the money!"
United States
Maya
$169 nightly
The price is $169
Sep 3 - Sep 4
Galapagos Coliving Ecuador Casa Tuna

7. Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
$220 nightly
The price is $220
Sep 3 - Sep 4
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

8. TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
$89 nightly
The price is $99
Sep 3 - Sep 4
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

9. Suite with spectacular ocean view, you will wake up to the sound of the sea.

Suite with spectacular ocean view, you will wake up to the sound of the sea.
Puerto Ayora
8.0 out of 10, Very Good, (1 review)
$140 nightly
The price is $154
Sep 8 - Sep 9
Suite with spectacular ocean view, you will wake up to the sound of the sea.

10. Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
$120 nightly
The price is $135
Sep 3 - Sep 4
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

11. 2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
$88 nightly
The price is $88
Sep 5 - Sep 6
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

12. Near Tortuga Bay Beach

Near Tortuga Bay Beach
Puerto Ayora
$70 nightly
The price is $78
Sep 3 - Sep 4
Near Tortuga Bay Beach

13. TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
$89 nightly
The price is $99
Sep 3 - Sep 4
TWO Bedrooms Apartment ON THE First Floor Forest View

14. Downtown Apartment

Downtown Apartment
Puerto Ayora
$76 nightly
The price is $76
Sep 3 - Sep 4
Downtown Apartment

15. Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Puerto Ayora
$102 nightly
The price is $102
Sep 4 - Sep 5
Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

16. ¡Bienvenido a tu hogar isleño en Galápagos!

¡Bienvenido a tu hogar isleño en Galápagos!
Puerto Ayora
$102 nightly
The price is $102
Sep 5 - Sep 6
¡Bienvenido a tu hogar isleño en Galápagos!

17. A centrally located suite in Santa Cruz within easy reach of everything

A centrally located suite in Santa Cruz within easy reach of everything
Puerto Ayora
$75 nightly
The price is $75
Sep 3 - Sep 4
A centrally located suite in Santa Cruz within easy reach of everything

18. Galapagos Family Vacation 3 BR. Centrally located and Ocean View

Galapagos Family Vacation 3 BR. Centrally located and Ocean View
Puerto Ayora
10.0 out of 10, Exceptional, (28 reviews)
"Great communication with host, gave us information ahead of time for laundry services and taxi. Clean and wonderful property close to everything and great views."
United States
Amanda
$435 nightly
The price is $467
Sep 14 - Sep 15
Galapagos Family Vacation 3 BR. Centrally located and Ocean View

19. Dominga Terrace

Dominga Terrace
Unknown
$98 nightly
The price is $98
Sep 6 - Sep 7
Dominga Terrace

20. Galapagos Apartment-Darwin

Galapagos Apartment-Darwin
Puerto Ayora
$80 nightly
The price is $89
Sep 8 - Sep 9
Galapagos Apartment-Darwin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isla Santa María Hotel Reviews

Find out more about Isla Santa María

Everything you need to know about Isla Santa María vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Isla Santa María vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Isla Santa María vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Isla Santa María vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Isla Santa María. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Isla Santa María in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $71 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Isla Santa María rentals

At Expedia, we put the best Isla Santa María vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Isla Santa María rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Isla Santa María vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Isla Santa María. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Isla Santa María?

Yes, we have vacation rentals in Isla Santa María near Galápagos National Park, or you can go with a more secluded option if you're looking for extra privacy while you relax.

What are some of the best vacation rentals that Isla Santa María has to offer?

Villa Galapagos: Visitors like this Isla Santa María vacation home rental. It is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What’s there to see and do in Isla Santa María?

Family-friendly attractions include Galápagos National Park, whereas Post Office Bay is a spot to enjoy the outdoors. Other places in town to visit include Punta Suarez.

What’s a vacation rental in Isla Santa María like?

Vacation rentals are private accommodations you can stay in for several days or longer in Isla Santa María. Vacation rentals provide amenities such as WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from public hotel elevators and busy reception areas while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a family trip.