Isle of Palms, FL

Jacksonville

Popular places to visit

Pretty

Mayo Clinic Florida

4.5/5(433 reviews)

Though Mayo Clinic Florida might be what brings you to town, perhaps you'll have a chance to explore more of Jacksonville while you are here.

Mayo Clinic Florida
Jacksonville Naval Air Station

Jacksonville Naval Air Station

4/5(300 reviews)

After visiting Jacksonville Naval Air Station, make a plan to see the other sights and activities in Jacksonville. Experience the lively festivals or attend a sporting event in this family-friendly area.

Jacksonville Naval Air Station
EverBank Field which includes a lake or waterhole

EverBank Stadium

4/5(386 reviews)

Capable of seating over 80,000 fans, this modern football stadium is the exciting home of the Jacksonville Jaguars, international soccer games and music events.

EverBank Stadium
Jacksonville Zoo and Gardens showing zoo animals

Jacksonville Zoo and Gardens

4.5/5(463 reviews)

Admire thousands of animals and plants across entertaining exhibits in this family-friendly zoo that also has a children’s play area and a 4-D experience.

Jacksonville Zoo and Gardens
The Clubhouse at TCP Sawgrass where The Players Golf Tournament was televised.

TPC Sawgrass

4.5/5(293 reviews)

Enjoy a round of golf in Ponte Vedra Beach at TPC Sawgrass. Stroll along the area's seaside or experience its acclaimed theater scene.

TPC Sawgrass
Jacksonville Beach Pier which includes general coastal views, fishing and a sunset

Jacksonville Beach Pier

4.5/5(264 reviews)

Stroll along this charming fishing pier that extends into the Atlantic Ocean. Enjoy the tranquil surroundings in your pursuit of a big catch.

Jacksonville Beach Pier

Things to do

3 Hour Coastal Fun Cruise

3 Hour Coastal Fun Cruise

$150
per adult
3 Hour Coastal Fun Cruise
1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports

1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports

$140
per traveler
90% of travellers recommend
1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports
Jacksonville Jaguars Football Game at EverBank Stadium

Jacksonville Jaguars Football Game at EverBank Stadium

$89
per adult
Jacksonville Jaguars Football Game at EverBank Stadium
Learn what lurks beneath the waves.

Jacksonville Ghosts and Ghouls Tour By US Ghost Adventures

$32
per adult
100% of travellers recommend
Jacksonville Ghosts and Ghouls Tour By US Ghost Adventures
Chocolate Bar Class

Chocolate Bar Class - Hands on class

$20
per adult
Chocolate Bar Class - Hands on class
Jax Urban Core Brewery Tour in Jacksonville

Jax Brewery Tour (Drinks Included)

$135
per adult
Jax Brewery Tour (Drinks Included)
See all activities in Jacksonville

Isle of Palms Hotel Deals

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL
$166 nightly
The price is $188 total per night from Oct 12 to Oct 13
$188 total
Oct 12 - Oct 13
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (424 reviews)
"This property is closed to the Mayo Clinic"

Reviewed on Sep 3, 2025

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N, Jacksonville Beach, FL
$174 nightly
The price is $197 total per night from Sep 21 to Sep 22
$197 total
Sep 21 - Sep 22
Total with taxes and fees
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Our guests praise the pool and the bar in ...
8.8/10 Excellent! (3,193 reviews)
"This hotel was so nice and smelled so yummy"

Reviewed on Sep 16, 2025

Margaritaville Jacksonville Beach
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr, Jacksonville, FL
$164 nightly
The price is $186 total per night from Sep 26 to Sep 27
$186 total
Sep 26 - Sep 27
Total with taxes and fees
Stay at this 4-star eco-certified hotel in Jacksonville. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,294 reviews)
"Everything was Excellent"

Reviewed on Sep 15, 2025

Hyatt Regency Jacksonville
Omni Amelia Island Resort & Spa

Omni Amelia Island Resort & Spa

4 out of 5
39 Beach Lagoon Road, Fernandina Beach, FL
$283 nightly
The price is $318 total per night from Sep 21 to Sep 22
$318 total
Sep 21 - Sep 22
Total with taxes and fees
Stay at this 4-star beach resort in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (1,007 reviews)
"We absolutely loved our stay this weekend at the Omni. The staff were great and the grounds were outstanding. Our only hitch was our shower was broken. The handle was broken and water would not flow. We did not notice until after 10, and it took several minutes for someone to answer the phone; we ..."

Reviewed on Sep 14, 2025

Omni Amelia Island Resort & Spa
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road, I-95 Exit 344 (Butler Boulevard), Jacksonville, FL
$74 nightly
The price is $84 total per night from Sep 21 to Sep 22
$84 total
Sep 21 - Sep 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,743 reviews)
"Seems to me people whonuse this app get old outdated rooms in need of remodeling"

Reviewed on Sep 12, 2025

Wyndham Garden Jacksonville
Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

3 out of 5
14565 Duval Rd, Jacksonville, FL
$89 nightly
The price is $101 total per night from Oct 19 to Oct 20
$101 total
Oct 19 - Oct 20
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (2,068 reviews)
Safe trip
"Good clean and quiet"

Reviewed on Sep 16, 2025

Hyatt Place Jacksonville Airport
See all 3,103 properties in Isle of Palms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Isle of Palms

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Atlantic Shores

Atlantic Shores might not have many top sights, but Pablo Plaza Shopping Center and Oceanfront Park are two attractions nearby that you can check out.

Atlantic Shores
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Old Ponte Vedra Beach

If you're spending some time in Old Ponte Vedra Beach, Ponte Vedra Beach and Mickler Beach are top sights worth seeing.

Old Ponte Vedra Beach
Trio lobster

Deerwood

4.5/5(67 area reviews)

If you're looking for some top things to see and do in Deerwood and surrounding area, you can visit St. Johns Town Center and UNF Arena.

Deerwood
Ponte Vedra Beach.

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

Sawgrass
The Clubhouse at TCP Sawgrass where The Players Golf Tournament was televised.

Palm Valley

While visiting Palm Valley, you might make a stop by sights like TPC Sawgrass and Cornerstone Park.

Palm Valley
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Arlington

Mid-century modern architecture abounds in this area, with notable homes by architects like Robert C. Broward. Explore attractions such as Fort Caroline, Jacksonville Arboretum & Gardens, and Tree Hill Nature Center, while enjoying easy access via JTA bus routes and major highways.

Arlington
See our Where To Stay guide

Isle of Palms, FL

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