Florida may have travel restrictions in place due to COVID-19.

Photo by Ronald Wilson

Find Spa Resorts & Hotels in Lake City, FL from $58

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Top Lake City Resorts & Hotels with Spas

Comfort Suites Lake City
2.5 out of 5
3690 W Us Highway 90, Lake City, FL
Free CancellationReserve now, pay when you stay
The price is $94 per night from Jan 20 to Jan 21
4.7/5Exceptional! (988 reviews)

"Property is nicely located near I-75. It’s clean and nicely decorated."…"

Reviewed on Jan 4, 2021

Comfort Suites Lake City
Hampton Inn & Suites Lake City, FL
2.5 out of 5
450 SW Florida Gateway Drive, Lake City, FL
Free CancellationReserve now, pay when you stay
The price is $107 per night from Jan 22 to Jan 23
4.6/5Exceptional! (415 reviews)
Clean & Comfortable

"The suite was large and able to accommodate my husband & I plus our 4 grown (high school & college aged) kids. It was very clean which made it very comfortable for us. The breakfast was very nice and the staff were all friendly. Would definitely return!"…"

Reviewed on Jan 7, 2021

Hampton Inn & Suites Lake City, FL
Best Western Plus Lake City
2.5 out of 5
350 SW Florida Gateway Dr, Lake City, FL
Free CancellationReserve now, pay when you stay
The price is $89 per night from Jan 24 to Jan 25
4.4/5Wonderful! (1,000 reviews)

"Clean hotel. Check-In was smooth. Comforting to know there is a clerk at the front desk 24/7."…"

Reviewed on Jan 11, 2021

Best Western Plus Lake City
You could be seeing lower prices

You could be seeing lower prices

With member prices, you could save 10% or more right now on thousands of properties.
Fairfield Inn & Suites Lake City
2.5 out of 5
538 Sw Corporate Dr, Lake City, FL
Free CancellationReserve now, pay when you stay
The price is $84 per night from Jan 24 to Jan 25
4.3/5Excellent! (611 reviews)

"Clean, COVID precautions well observed, convenient and great staff. David at the front desk was super: friendly, helpful, and welcoming."…"

Reviewed on Jan 17, 2021

Fairfield Inn & Suites Lake City
Holiday Inn & Suites Lake City
3 out of 5
213 Sw Commerce Dr, Lake City, FL
Free Cancellation
The price is $92 per night from Jan 23 to Jan 24
4.1/5Very Good! (769 reviews)

"The most comfortable beds. Friendly staff. And good food service onsite. I’d highly recommend!"…"

Reviewed on Jan 4, 2021

Holiday Inn & Suites Lake City
Econo Lodge Live Oak
2 out of 5
6811 N Us 129 & I 10, Live Oak, FL
Free CancellationReserve now, pay when you stay
The price is $75 per night from Jan 18 to Jan 19
3.4/5 (195 reviews)
nice stay

"We were permitted to check in early. The room was already cool and we appreciated that it was non smoking and fit that description."…"

Reviewed on Aug 27, 2020

Econo Lodge Live Oak
Baymont by Wyndham Lake City
2.5 out of 5
3598 W Us Highway 90, Lake City, FL
Free CancellationReserve now, pay when you stay
The price is $58 per night from Jan 31 to Feb 1
3/5 (708 reviews)

"Good room, but AC had one setting only (freezing or hot) and shower knob wouldn’t turn off without constant dripping. Our room was not cleaned one of the days but I told them and they never missed us again. Our room had a little dingy smell to it upon arrival but I sprayed some Lysol around and fabreeze ..."…"

Reviewed on Nov 30, 2020

Baymont by Wyndham Lake City
Don't see what you're looking for?
We've got more Resorts & Hotels with Spas. Find the right one for you.
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lake City Resorts & Spa Travel Guide

Indulge Yourself with a Lake City Spa Vacation

There is no treatment like spa treatment. It's time to take a trip where you can get all your worries massaged away in Lake City. If you are searching for extravagant accommodations or reasonable selections, we can help you find the ideal place to stay. You'll find in having you take it easy. Pack up your luggage and forget your concerns to initiate your pressure-free holiday.

We Have Divine Spa Deals in Lake City

Once you've checked-in to your resort you can unload your tension and your bag. Unwind and unpack your luggage. After that you can book your first appointment to indulge yourself at a nearby spa. After you've spent the afternoon getting a massage, decompressing within the sauna, or sunning by the pool, you can put on your explorer's hat and begin to uncover the hidden gems of Lake City. Discovering new restauraunts, curio shops, or a beautiful park can be one of the many highlights of your holiday. If you're not sure where to begin, ask your hotel's porter to get a sense for what Lake City has to offer. There is no better source than a local to point you to an exciting evening out or to a cafe to enjoy a few cocktails at and have an easy-going time. Regardless of where you end up, just be sure to hang loose. Your spa vacation shouldn't be anything but super relaxing.

With so many ways to wind you down, Lake City consistently ranks as one of the best spots for a spa vacation.

Frequently asked questions

Looking for a spa hotel in Lake City?
Soothe the senses with some time in one of our wonderful spa hotels. Travelers recommend the lakes and gourmet restaurants in Lake City. Be sure to enjoy the shopping during your stay. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Lake City?
Best Western Plus Lake City is a top spa hotel featuring an indoor pool and a fitness center. Other popular spa hotels in Lake City include Holiday Inn & Suites Lake City and Hampton Inn & Suites Lake City, FL.
How many spa hotels will I find in Lake City?
Among Expedia’s 124 accommodation options in Lake City, there are 7 spa hotels.
What's there to see and do in Lake City?
When you’re in Lake City, enjoy exploring the sights and attractions here including Ichetucknee Springs State Park, Florida Department of Transportation, and Lake City Mall. If you have extra time while you’re in the area, you might want to stop by North Florida Speedway and Osceola National Forest.
What is a Lake City spa hotel?
Spa hotels in Lake City provide lodging and have a full on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

Recent reviews of Lake City hotels

More trip options