Portageville, MO

Travel Guide

New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61 Portageville MO
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (798 reviews)
"Plain outside, nice room, inside of microwave had rust, smoke detector missing, very low price was nice."

Reviewed on Sep 15, 2026

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New Orleans Inn Portageville
Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

3 out of 5
1317 E Highway 84 Hayti MO
$102 nightly
The price is $116 total per night from Oct 11 to Oct 12
$116 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Hayti. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,004 reviews)
"Great stay, clean rooms, excellent breakfast! Will stay again if we are in the area."

Reviewed on Sep 21, 2026

Drury Inn & Suites Hayti Caruthersville
The Farmstead Hotel

The Farmstead Hotel

2.5 out of 5
778 E 3rd St Caruthersville MO
$86 nightly
The price is $97 total per night from Sep 23 to Sep 24
$97 total
Sep 23 - Sep 24
Total with taxes and fees
Stay at this hotel in Caruthersville. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.6/10 Excellent! (610 reviews)
"Clean, comfortable and convenient to the casino. Caruthersville is in a rural part of Missouri. We travelled there for a funeral. There are zero amenities at this hotel, but we weren't there to get a resort experience. With that said , it's right on the Mississippi River, so that was cool."

Reviewed on Sep 20, 2026

The Farmstead Hotel
See all 69 properties in Portageville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Duck Hunting, Fishing or Relaxing Family Vacation

Duck Hunting, Fishing or Relaxing Family Vacation

Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (246 reviews)
"The house and property were very clean and a great location. We will definitely be back."

Reviewed on Sep 20, 2026

Duck Hunting, Fishing or Relaxing Family Vacation
Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!

Hornbeak TN
Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.4/10 Exceptional! (37 reviews)
"The place was nice, however the air-conditioning was out and the refrigerator did not work. It's early September in the south, no a/c means a miserable experience. After some time and several calls/messages I was able to reach the host. He said there was nothing he could do about it other than a ..."

Reviewed on Sep 7, 2026

Come and relax at the Refuge at beautiful Reelfoot Lake!
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (11 reviews)
"Great place to stay"

Reviewed on Jul 27, 2026

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
See all properties in Portageville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

When is the best time to visit Portageville?
The best time to visit Portageville is from March through June, when the climate is most pleasant for exploring. For fewer crowds and better value, the quieter months of November through February are a good bet, offering a cooler experience. These months can be ideal for travelers seeking a more relaxed visit.
Can I book a refundable hotel in Portageville?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Portageville by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Portageville with Expedia?
Expedia makes it easier to plan your Portageville trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Portageville?
The best choice depends on your travel style. Hotels in Portageville can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Portageville trip on Expedia?
Once you've booked your Portageville trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Portageville trip?
Expedia offers customer support before, during, and after your Portageville trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Portageville?
If it's your first trip to Portageville, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Portageville hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Portageville hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Cities near Portageville

A flock of birds flying over a field with bare trees in the background.

Tiptonville

A swampy area with water lilies and tall trees.

Hayti

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