Los Anastacios Vacation Rentals

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Check prices for these dates

In two weeks
Jan 30 - Feb 1
In two months
Mar 13 - Mar 15
In three months
Apr 10 - Apr 12
In four months
May 8 - May 10

Our top choices for Los Anastacios vacation rentals

Tree House, Mountain View | View from room

Treehouse in Jaramillo

Lucero - Luxury Treehouses
3.5 star property
8.8 out of 10, Excellent, (5 reviews)
"Print or save your map beforehand. Do not exit onto a gravel road! The property is located inside a golf community. The map on the listing is incorrect! As of October 2025 all maps including Google, Waze and Apple maps all have the wrong and remote location. The correct location is Lucero. We had a beautiful experience! Everyone was so pleasant and welcoming. We had an amazing stay!"
United States
John
$336 nightly
The price is $370
Jan 19 - Jan 20
Total with taxes and fees
Lucero - Luxury Treehouses
Superior Suite, 1 King Bed, Valley View, Mountainside | Private spa tub

Apartment in Boquete

Casa Reina by Villa Alejandro
3.5 star property
8.4 out of 10, Very Good, (17 reviews)
"Road coming to the property is terrible. If you have a car it may not make it. Definitely need a suv or truck. Most taxis will not come to this location. Room was nice and clean. Great mountains view. Queen bed was only a double. When asked about it they never answered me. "
Canada
David
$100 nightly
The price is $110
Jan 19 - Jan 20
Total with taxes and fees
Casa Reina by Villa Alejandro
Honeymoon Cabin, 1 King Bed, Valley View, Mountainside | Living area | 100-cm flat-screen TV with digital channels, TV, Netflix

Villa in Boquete

Villa Alejandro
3.5 star property
8.6 out of 10, Excellent, (134 reviews)
"DOOR DOESN’T LOCK. I was able to open my room door while it was locked. Felt very unsafe. Tiny room in a VERY public space. Had to walk through a kitchen full of strangers to arrive at my room, there is no other entrance. Very noisy neighbors all night, got no sleep. Room is clean and area is nice looking but that’s it. Very expensive for what they offer. DO NOT RECOMMEND! Terrible experience."
United States
Jacob
$79 nightly
The price is $87
Jan 20 - Jan 21
Total with taxes and fees
Villa Alejandro
Front of property

Condo resort in Alto Boquete

Aires frescos de Boquete
2.0 star property
9.0 out of 10, Wonderful, (4 reviews)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
$82 nightly
The price is $90
Jan 19 - Jan 20
Total with taxes and fees
Aires frescos de Boquete
Premier Suite, 1 King Bed, Garden View | Premium bedding, down comforters, individually decorated

Apartment in Boquete

El Cielo by Villa Alejandro
3.5 star property
9.4 out of 10, Exceptional, (95 reviews)
"Really beautiful property "
United States
Jason
$116 nightly
The price is $128
Jan 20 - Jan 21
Total with taxes and fees
El Cielo by Villa Alejandro
Condo, 2 Bedrooms | 2 bedrooms, iron/ironing board, free WiFi

Condo in El Tropezón

Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
3.0 star property
$214 nightly
The price is $236
Jan 21 - Jan 22
Total with taxes and fees
Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
Exterior

Cabin in Alto Boquete

Linda Vista Cabins
3.0 star property
9.2 out of 10, Wonderful, (17 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
$50 nightly
The price is $55
Feb 1 - Feb 2
Total with taxes and fees
Linda Vista Cabins
Garden

Apartment in Boquete

Aparthotel Los Pinos
2.5 star property
8.4 out of 10, Very Good, (16 reviews)
"The place was spacious, clean and comfortable. Great location and easy parking."
United States
Rebecca
$119 nightly
The price is $131
Jan 19 - Jan 20
Total with taxes and fees
Aparthotel Los Pinos
1 bedroom, Egyptian cotton sheets, pillowtop beds, free WiFi

Aparthotel in El Tropezón

Downtown Suites
3.0 star property
9.0 out of 10, Wonderful, (101 reviews)
"Good location, nice rooms, great value."
United States
Robert
$98 nightly
The price is $109
Feb 3 - Feb 4
Total with taxes and fees
Downtown Suites
Family Apartment, 2 Bedrooms | Living area | 50-inch Smart TV with digital channels

Apartment in David

Peace N' Green
3.0 star property
$47 nightly
The price is $52
Jan 20 - Jan 21
Total with taxes and fees
Peace N' Green
Family House, 2 Bedrooms, Garden View | 3 bedrooms, minibar, desk, free WiFi

Vacation Home in Tijeras

Casa Little Italy
3.0 star property
6.0 out of 10, (1 review)
"Didn't accept credit card payment "
Mexico
ANGELO
$80 nightly
The price is $88
Jan 19 - Jan 20
Total with taxes and fees
Casa Little Italy
Deluxe Studio Suite, 1 King Bed, Non Smoking, Mountain View | Premium bedding, down comforters, individually decorated

Villa in Los Naranjos

Casa Mate by Villa Alejandro
3.5 star property
2.0 out of 10, (1 review)
$104 nightly
The price is $114
Jan 20 - Jan 21
Total with taxes and fees
Casa Mate by Villa Alejandro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Los Anastacios Hotel Reviews

Hampton by Hilton David

Hampton by Hilton David

10/10 Excellent
"Lindo hotel, ubicado en el centro con muchas opciones de restaurantes y cosas cerca, area segura, personal amable, buen desayuno. "
Isabel 2-night trip
Posted 1 day ago
Hampton by Hilton David

Find out more about Los Anastacios

Everything you need to know about Los Anastacios vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Los Anastacios vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Los Anastacios vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Los Anastacios vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Los Anastacios. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Los Anastacios in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $52 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Los Anastacios rentals

At Expedia, we put the best Los Anastacios vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Los Anastacios rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Los Anastacios vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Los Anastacios. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in Los Anastacios?

Yes, we offer vacation rentals close to popular points of interest in Los Anastacios, or you can go with a more remote option if you're looking for relaxation.

What are some of the best vacation rentals in Los Anastacios?

House in Boquete with king beds and hot tub: Visitors like this Los Anastacios vacation home rental. It is located in the mountains and has a balcony, a garden, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the hot tub in this rental home to help you unwind.

What’s there to see and do in Los Anastacios?

While you're exploring the area, Parque de las Madres and Miguel de Cervantes Saavedra Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Boquete Library and Boquete Community Players Theater and Events Center.

What are vacation rentals like in Los Anastacios?

Vacation rentals are privately owned properties you can book for a few days or a quick weekend in Los Anastacios. Vacation rentals feature amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, vacation rentals can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family gatherings.