Los Anastacios Vacations from $774

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Your Los Anastacios Vacation

When you choose a Los Anastacios vacation package, you can kick back and enjoy your escape to the fullest. Uncover the highlights of this lively city knowing that all your travel needs have been organized before you go. Every good trip to Los Anastacios has to include a bit of sightseeing. Where to go first? Balneario La Nueva Barranca and Los Pozos de Caldera are main attractions. Expedia is here to help you escape your routine. Tailor your vacation to Los Anastacios to suit your travel style, whatever that may be.

The Latest Los Anastacios vacation packages

Price found within the past 48 hours. Click for updated prices.

Yoo by Wynwood House

Calidonia

$774

per person

Oct 19 - Oct 23

found 1 day ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

9.4/10 Exceptional! (6 reviews)

Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.

Reviewed on Jul 26, 2025

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,090

per person

Oct 14 - Oct 21

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9.2/10 Wonderful! (1,001 reviews)

Beautiful historic hotel we stayed there for 5 nights with a group of 33 people celebrating my brother’s 50 th birthday. very central, you can walk to go shopping or eating and dining at the roof top restaurants in the hotel or around Casco. The cocktails at the bar delicious and the breakfast was great variety, food was fresh. I’d rate the hotel Uber from there quick and cheap…….,10/10 great experience. The staff was also nice and very accommodating.

Reviewed on Sep 2, 2026

Megapolis Hotel Panamá

San Francisco

$914

per person

Nov 5 - Nov 10

found 2 days ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.4/10 Very Good! (1,692 reviews)

Nice

Reviewed on Sep 3, 2026

Casa Mallet by Wynwood House

Casco Viejo

Save 100% on your flight

$1,485

per person

Nov 12 - Nov 18

found 1 day ago

Roundtrip flight included

Georgetown (GEO) to Panama City (PTY)

9.8/10 Exceptional! (29 reviews)

Nice apartment ! Clean and great location

Reviewed on Aug 13, 2026

Hotel Casa Panamá

Casco Viejo

$839

per person

Oct 14 - Oct 21

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

7.6/10 Good! (745 reviews)

The only reason I’m giving the hotel a 3 star is because we weren’t able to sleep all weekend. It’s not the hotels fault but we were unable to rest at all. The location is right on the main road so all the cars are beeping at all hours and they have a rooftop which blast music all night long. If the room would be sound proof it would have been great but unfortunately for us it wasn’t and we were dead tired and unable to rest.

Reviewed on Sep 2, 2026

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Los Anastacios Hotel Deals

Hotel Ciudad De David

Calle D Norte, Avenida 2da Este David Chiriqui

Fully refundableReserve now, pay when you stay

$79 nightly

$88 total

Oct 4 - Oct 5

Total with taxes and fees

ONDA Boquete

Ave. Fundadores Boquete Provincia de Chiriquí

$34 nightly

$37 total

Sep 6 - Sep 7

Total with taxes and fees

Hotel Panamonte

April 11 Ave Jaramillo Chiriqui

$160 nightly

$176 total

Sep 17 - Sep 18

Total with taxes and fees

9.4/10 Exceptional! (177 reviews)

"Great food and history!"

Reviewed on Aug 29, 2026

See all 238 properties in Los Anastacios

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Los Anastacios Vacation Packages

Los Anastacios Essential Information

Language	Spanish
Currency	Panamanian balboas
Local Welcome	¡Hola!
Local Goodbye	Adiós
Closest Airport	Enrique Malek Intl. Airport (DAV)
Population	1,100
Top Sights	Los Pozos de Caldera and Balneario La Nueva Barranca

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Frequently asked questions

How much does a Los Anastacios vacation package cost?

You'll find cheap prices from $774 on Expedia for your Los Anastacios getaway. However, a range of factors like the length of stay, hotel choice and season will influence how much your vacation to Los Anastacios costs.

What are the cheapest months to go to Los Anastacios?

You can generally find lower rates and greater availability in January, July and December. Explore our cheap Los Anastacios vacation packages and you could land some great off-season deals.

How many days is enough for Los Anastacios?

Usually, a handful of days is enough to tick off the major sights during your Los Anastacios vacation. However, if you'd like to have some time to rest or go on day trips, think about extending your trip.

How to find the best Los Anastacios package deals?

Start your search for a Los Anastacios package deal by entering your destination and preferred travel dates under our "Packages" tab. Then select a few filters, like "Property type" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the perfect Los Anastacios package deal straight away, just play around with your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Los Anastacios escape underway.

Is it cheaper to book a Los Anastacios vacation as a package?

You can enjoy significant savings on your Los Anastacios break by booking a tailored vacation package. Check the "Package" heading, then select your travel dates and destination to browse the best airfares and hotel prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.

When to book a vacation package to Los Anastacios?

If you've got your Los Anastacios vacation dates locked in, book as early as you can to snap up some fantastic deals. With Expedia, you can generally reserve some flights up to one year in advance. Prefer spontaneous getaways? Our last-minute deals are ideal for impromptu escapes.

How to plan a trip to Los Anastacios?

Choose when to travel: Check your schedule and pack your bags. Your favorite season and the activities available will also help you decide when to vacation in Los Anastacios.
Figure out your budget: Make sure you have enough money to pay for everything from meals and transportation to airfares and activities. Your hotel will probably be the largest expense during your trip to Los Anastacios.
Use our trip planning tool to discover Los Anastacios: Research every aspect of your trip to Los Anastacios with this comprehensive planner. Invite friends or family to collaborate on a group getaway, search for stays or things to do and make bookings.
Decide your trip length: Consider how long you want to spend discovering Los Anastacios. Plan your days so you can get to all the attractions and activities you're interested in at a leisurely pace.
Bundle your bookings: With your travel dates in order, you can combine your flights, car rental, hotels and more into a personalized Los Anastacios vacation package.
Book experiences or activities ahead of time: Whether it's entrance to a big attraction or a day trip in nature, you won't have to worry about missing out on Los Anastacios's highlights. Find all the fun things to do in Los Anastacios with our dedicated activity guide.

Does Expedia offer Book Now, Pay Later Los Anastacios vacation packages?

If you're like us, you love exploring new places but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Los Anastacios break across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can snap up great vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.