Midtown, MO

St. Louis

St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.
St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.
Midtown
Midtown
Midtown

Popular places to visit

Things to do


Midtown Hotel Deals

Element St. Louis Midtown

Element St. Louis Midtown

3 out of 5
3763 Forest Park Avenue St. Louis MO
$135 nightly
The price is $158 total per night from Mar 8 to Mar 9
$158 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (678 reviews)
Well run hotel. 1st class service from front desk to valet to bar service to breakfast to cleaning. Everyone worked as a team without any pretense. The 7th floor roof top is a perfect setting to cap off a night! Thank you!

Reviewed on Feb 26, 2026

Element St. Louis Midtown
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave St. Louis MO
$114 nightly
The price is $136 total per night from Mar 29 to Mar 30
$136 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the breakfast ...
7.8/10 Good! (1,005 reviews)
Mean black girl with cheap wig at front desk watch out!! Maintenance men were so sweet and helpful

Reviewed on Feb 24, 2026

Residence Inn by Marriott St Louis Downtown
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$94 nightly
The price is $110 total per night from Mar 4 to Mar 5
$110 total
Mar 4 - Mar 5
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,853 reviews)
Very friendly and helpfull staff. I did find a ball of hair in the bed under the top cover. That was kinda gross and the hot tub was lacking.

Reviewed on Feb 27, 2026

Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $146 total per night from Mar 9 to Mar 10
$146 total
Mar 9 - Mar 10
Total with taxes and fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,628 reviews)
Great place to stay. I recommend it and will stay again.

Reviewed on Feb 27, 2026

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
$105 nightly
The price is $122 total per night from Mar 29 to Mar 30
$122 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,088 reviews)
Staff Checking in was quick and easy.

Reviewed on Feb 27, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from Mar 4 to Mar 5
$106 total
Mar 4 - Mar 5
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,835 reviews)
Staff were great

Reviewed on Feb 27, 2026

Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Vacation Sale

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Other neighborhoods around Midtown

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The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Busch Stadium.

The Gate
Love this hotel.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Downtown West
Lafayette Square which includes a house and a garden

Lafayette Square

The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Busch Stadium, a few notable attractions nearby.

Lafayette Square
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.

The Grove
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Shaw

4.5/5(3 area reviews)

While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Shaw
Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End


Midtown, MO

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