Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Mission Valley Evolution Hospitality Hotels

See all 1,431 Hotels in Mission Valley
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

207 5th Ave, San Diego
4.5 out of 5.0
4.3 out of 5 (3,146 reviews)
Great hotel and great location. I would definetly come back and stay at this hotel again. - 

$187

$187
Map

Recently booked Mission Valley hotels

The Atwood
3.5 out of 5.0
Last booking: 1 minute ago
Comfort Inn & Suites San Diego - Zoo SeaWorld Area
3.0 out of 5.0
Last booking: 3 minutes ago
Days Inn San Diego Hotel Circle Near SeaWorld
3.0 out of 5.0
Last booking: 12 minutes ago
Homewood Suites by Hilton San Diego Mission Valley/Zoo
3.5 out of 5.0
Last booking: 30 minutes ago
La Quinta Inn & Suites San Diego SeaWorld/Zoo Area
3.0 out of 5.0
Last booking: 41 minutes ago
Homewood Suites by Hilton San Diego Hotel Circle/Sea World
0.0 out of 5.0
Last booking: 42 minutes ago
Super 8 San Diego Hotel Circle
2.5 out of 5.0
Last booking: 1 hour ago
Extended Stay America San Diego - Hotel Circle
3.0 out of 5.0
Last booking: 1 hour ago
Days Inn Mission Valley - Qualcomm - SDSU
2.5 out of 5.0
Last booking: 1 hour ago

Pocket Guide: Evolution Hospitality Hotels in Mission Valley

Search for hotels in Mission Valley on Expedia. You can easily find your hotels in Mission Valley using one of the methods below:

  • View our selection of featured hotels in Mission Valley
  • Use the map to find hotels in the Mission Valley neighborhood you prefer
  • Use the filters to see hotels in a specific area of Mission Valley, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Mission Valley
  • Enter your travel dates to view the best deals on hotels in Mission Valley - while they last