Mission Valley Vacations from $219

Book a Hotel + Flight or Car together to unlock savings

Your Mission Valley Vacation

With a vacation package to Mission Valley, you can spend less time planning and more time experiencing this interesting neighborhood. From its shopping to its dining, there's so much to discover here. Can't wait to do some sightseeing during your trip to Mission Valley? Don't miss nearby attractions like San Diego Zoo, Balboa Park and University of San Diego. Stop daydreaming and start doing. When you're ready to book your ideal vacation to Mission Valley, Expedia will help get you there.

The Latest Mission Valley Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hyatt Vacation Club at The Welk, San Diego Area

Hyatt Vacation Club at The Welk, San Diego Area

Lawrence Welk Resort Village
Save 100% on your flight
$219
per person
Oct 20 - Oct 23
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (1,998 reviews)
The Sofia Hotel

The Sofia Hotel

Downtown San Diego
$686
per person
Sep 19 - Sep 25
found 2 days ago
Roundtrip flight included
Dallas (DAL) to San Diego (SAN)
8.6/10 Excellent! (2,462 reviews)
The location is perfect: all was great except the bed comfort. But otherwise a beautiful hotel

Reviewed on Aug 11, 2026

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

Downtown San Diego
Save 100% on your flight
$644
per person
Oct 14 - Oct 18
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9/10 Wonderful! (1,466 reviews)
A+ Great Hotel.. My wife and I will totally come back and stay there again.

Reviewed on Aug 11, 2026

Los Bungalows

Los Bungalows

Save 100% on your flight
$292
per person
Oct 20 - Oct 23
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.2/10 Very Good! (546 reviews)
Urban Boutique Hotel

Urban Boutique Hotel

Downtown San Diego
Save 100% on your flight
$634
per person
Oct 14 - Oct 18
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (1,257 reviews)
This is a property to avoid, unfortunately, and especially at the price. The low quality of the rooms and in particular, the poor mattress quality, made our stay extremely uncomfortable. The beds have so little support that my lower back and hips were punished from side sleeping (stomach sleeping was impossible for me). The bathrooms and sinks weren't in good shape; our bathroom had a smudged mat in it and the finish was coming off of the tub. I understand that wear and tear happens, but the mat could have at least been cleaned or replaced. The desk staff did their best to help with issues. Of course, they are limited in what they can do, but they were nice and attentive. The location of the hotel is right in Little Italy and next to downtown. Walking out of the hotel and around the corner of the building opens onto a vibrant market full of shops and restaurants. My score for this is based on the comfort of the room itself, the price for value, and my experiences in other urban hotels of this type that attempt to be boutique. For example, we stayed at Hotel Lucia in Portland earlier this year, which is the same type of boutique hotel in the city, and it blew this hotel away in terms of comfort, amenities, and cleanliness. You would be better off getting the same quality for cheaper at nearby Motel 6 or just paying a bit extra a night for a superior Little Italy hotel than staying here. Sadly, you should avoid this hotel.

Reviewed on Aug 10, 2026

Where to stay in Mission Valley

Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley
A grand building with a central fountain, palm trees, and a flag.

Downtown San Diego

3 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

A pier extending into calm waters with people on it and a sandy beach with seaweed and a few individuals.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

A sandy beach with a lifeguard tower, ocean waves, and people in the distance.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

A lively street scene with outdoor seating at various bars and restaurants, including 'The Field' and 'Sloppy Joe's'.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

1 out of top 10 points of interest in this area

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Mission Valley Hotel Deals

Handlery Hotel

Handlery Hotel

950 Hotel Cir N San Diego CA
$119 nightly
$137 total
Aug 23 - Aug 24
Total with taxes and fees
Handlery Hotel
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$88 nightly
$102 total
Sep 7 - Sep 8
Total with taxes and fees
Days Inn by Wyndham San Diego Hotel Circle
Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

2270 Hotel Cir N San Diego CA
Fully refundable
$122 nightly
$141 total
Aug 24 - Aug 25
Total with taxes and fees
Crowne Plaza San Diego - Mission Valley by IHG
See all 8,915 properties in Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mission Valley attractions

A bridge at night with its lights reflecting on the water.

Hotel Circle

8.2/10 (6,358 reviews)
Hotel Circle is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Check out the shops and top-notch restaurants in this family-friendly area.
See properties
A large stadium with a parking structure, surrounded by hills and a highway.

Snapdragon Stadium

8.4/10 (243 reviews)
Catch an event at Snapdragon Stadium during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

Fashion Valley Mall

9.0/10 (111 reviews)
You can search for that perfect souvenir at Fashion Valley Mall during your stay in San Diego. Take in the fascinating museums and beautiful sunsets in this walkable area.
See properties

Mission Valley Mall

8.8/10 (53 reviews)
You can do some window-shopping at Mission Valley Mall during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

Town and Country San Diego

Learn about the events happening at Town and Country San Diego during your trip to San Diego. Wander the beautiful beaches and seaside in this family-friendly area.
See properties

Legacy International Center

Enjoy an outing to Legacy International Center during your stay in San Diego. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants.
See properties

SDSU Mission Valley

Explore the campus of SDSU Mission Valley as part of your travels around San Diego. Check out the shops and top-notch restaurants in this family-friendly area.
See properties

Things to do

San Diego Padres Baseball Game at Petco Park

San Diego Padres Baseball Game at Petco Park

$44
per adult
San Diego Padres Baseball Game at Petco Park
San Diego Afternoon Sail

Spectacular Afternoon Sail on San Diego Bay

$96
per adult
Spectacular Afternoon Sail on San Diego Bay
See all activities in San Diego

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.