Mission Valley Vacations from $456
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Your Mission Valley Vacation
With a vacation package to Mission Valley, you can spend less time planning and more time experiencing this interesting neighborhood. From its shopping to its dining, there's so much to discover here. Can't wait to do some sightseeing during your trip to Mission Valley? Don't miss nearby attractions like San Diego Zoo, Balboa Park and University of San Diego. Stop daydreaming and start doing. When you're ready to book your ideal vacation to Mission Valley, Expedia will help get you there.
The Latest Mission Valley Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel
Downtown San Diego
Price was $1,108, price is now $505 per person
$505
per person
Jan 24 - Jan 31
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to San Diego (SAN)
8.4/10 Very Good! (1,619 reviews)
Great hotel . Convenient location.. close to restaurants and very walkable. Very friendly staff
Reviewed on Nov 9, 2025
Margaritaville Hotel San Diego Gaslamp Quarter
Downtown San Diego
Save 100% on your flight
Price was $1,463, price is now $731 per person
$731
per person
Jan 24 - Jan 31
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to San Diego (SAN)
9/10 Wonderful! (1,082 reviews)
Great location. Very nice property
Reviewed on Nov 11, 2025
La Jolla Cove Suites
Village of La Jolla
Price was $1,416, price is now $795 per person
$795
per person
Jan 21 - Jan 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
7/10 Good! (1,052 reviews)
Great beach hotel. Many site seeing spots, shops, and restaurants in walking distance. Did not drive while there.
Reviewed on Nov 6, 2025
Sentral Gaslamp Quarter
Downtown San Diego
Save 100% on your flight
Price was $1,388, price is now $793 per person
$793
per person
Jan 24 - Jan 31
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to San Diego (SAN)
9.2/10 Wonderful! (462 reviews)
Room was clean and nicely decorated. The staff were very friendly and helpful. Great location with numerous restaurants in easy walking distance.
Reviewed on Nov 9, 2025
Where to stay in Mission Valley
Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley
Downtown San Diego
3 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Mission Valley Hotel Deals
Hilton San Diego Mission Valley
901 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Nov 18 to Nov 19
$131 total
Nov 18 - Nov 19
Total with taxes and fees
8/10 Very Good! (2,160 reviews)
Great hotel overall
Reviewed on Nov 11, 2025
Legacy Resort Hotel & Spa
875 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $194 total per night from Nov 18 to Nov 19
$194 total
Nov 18 - Nov 19
Total with taxes and fees
9/10 Wonderful! (2,922 reviews)
Very nice hotel. Clean, friendly Front Desk Staff, food.
Reviewed on Nov 8, 2025
Handlery Hotel
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $112 total per night from Dec 1 to Dec 2
$112 total
Dec 1 - Dec 2
Total with taxes and fees
8.2/10 Very Good! (2,209 reviews)
Room was very nice and spacious
Reviewed on Nov 6, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Mission Valley
Hotel Circle
4/5(1,397 reviews)
Hotel Circle is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Check out the shops and charming cafes in this family-friendly area.
Snapdragon Stadium
4/5(183 reviews)
Catch an event at Snapdragon Stadium during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
Fashion Valley Mall
4.5/5(84 reviews)
You can search for that perfect souvenir at Fashion Valley Mall during your stay in San Diego. Take in the fascinating museums and beautiful sunsets in this walkable area.
Things to do
San Diego Whale Watching & Dolphin Cruise
$57
per adult
86% of travellers recommend
San Diego Old Town Trolley Hop-On Hop-Off Tour
$95
per adult
94% of travellers recommend
San Diego Sunset Cruise from Mission Bay
$40
per adult
78% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.