Hotels near Central San Diego

See all 98 Hotels in Central San Diego
Ramada San Diego North Hotel and Conference Center
Ramada San Diego North Hotel and Conference Center

5550 Kearny Mesa Rd, San Diego 92111

3.0 out of 5.0
3.7 out of 5 (2,779 reviews)

Surrounded by palm trees, this hotel is situated on 5 acres of land, 9 miles from La Jolla beaches, 8 miles from the San Dieg …

$82
Courtyard by Marriott San Diego Central
Courtyard by Marriott San Diego Central

8651 Spectrum Center Blvd, San Diego 92123

3.0 out of 5.0
4.3 out of 5 (604 reviews)

Situated in the business district, this hotel is within 6 mi (10 km) of Qualcomm Stadium, University of San Diego, and Fashio …

$125
Hampton Inn San Diego-Kearny Mesa
Hampton Inn San Diego-Kearny Mesa

5434 Kearny Mesa Rd, San Diego 92111

2.5 out of 5.0
4.5 out of 5 (442 reviews)

Located in the heart of San Diego, this hotel is within 6 mi (10 km) of Fashion Valley Mall, University of San Diego, and …

$107
Holiday Inn San Diego North Miramar
Holiday Inn San Diego North Miramar

9335 Kearny Mesa Rd, San Diego 92126

3.0 out of 5.0
4.2 out of 5 (356 reviews)

Situated in San Diego, this hotel is within 9 mi (15 km) of Marine Corps Air Station Miramar, University of California-San …

$117
Hilton Garden Inn San Diego Mission Valley Stadium
Hilton Garden Inn San Diego Mission Valley Stadium

3805 Murphy Canyon Rd, San Diego 92123

3.0 out of 5.0
3.2 out of 5 (161 reviews)

Situated in San Diego, this hotel is 2.3 mi (3.8 km) from Qualcomm Stadium and 2.7 mi (4.4 km) from Mission Basilica San Dieg …

$103
The Sofia Hotel
The Sofia Hotel

150 W Broadway, San Diego 92101

3.5 out of 5.0
4.3 out of 5 (5,854 reviews)

In the heart of downtown San Diego, this historic boutique hotel is 2 blocks from Horton Plaza, 4 blocks from the Gaslamp …

$120
Paradise Point Resort & Spa
Paradise Point Resort & Spa

1404 Vacation Rd, San Diego 92109

4.0 out of 5.0
3.8 out of 5 (2,002 reviews)

Paradise Point Resort & Spa is on a private tropical island in San Diego’s Mission Bay. SeaWorld® is a 4-minute drive away …

$151
Hotel del Coronado
Hotel del Coronado

1500 Orange Ave, Coronado 92118

4.0 out of 5.0
4.2 out of 5 (1,379 reviews)

One of the largest and oldest resorts on the Pacific Coast, Hotel del Coronado occupies 28 acres of oceanfront property at …

$289
Loews Coronado Bay Resort
Loews Coronado Bay Resort

4000 Coronado Bay Rd, Coronado 92118

4.0 out of 5.0
4.3 out of 5 (3,705 reviews)

With San Diego Bay on one side and the Pacific Ocean on the other, this resort sits on a 15-acre peninsula 4 miles from …

$209
The Westin San Diego
The Westin San Diego

400 W Broadway, San Diego 92101

4.0 out of 5.0
4.2 out of 5 (2,808 reviews)

The striking, 26-story Westin San Diego is 1 block from the trolley station, 3 blocks from Horton Plaza shopping, and 5 block …

$135
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Where To Stay In Central San Diego

Central San Diego, San Diego Hotel Information

Expedia.com offers a selection of 98 hotels in Central San Diego. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs.

Expedia.com will not only save you time, but also money when booking your stay at a hotel in Central San Diego. Making reservations so you can stay within your budget is easy with us.

Expedia.com even provides you with a map so you may find hotels in the Central San Diego neighborhood you prefer.

Go ahead. Enter your travel dates to view the best offers on hotel rooms in Central San Diego, California now!

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These areas in SoCal will welcome you like a local. Feast on fresh homemade pasta in Little Italy, check out the Padres Petco Park stadium in East Village, or stroll along the harbor and check out the Star of India within easy access of your hotel. No matter what part of Central San Diego you wish to explore, Expedia has the right accommodations for you. From family-friendly suites with pool access for the kiddos to romantic hotels to spend a getaway with your sweetheart, you’ll find it all here.

Score the lowest rates on hotels in Central San Diego when you browse our selection. You’ll also find the hottest discounts on Downtown San Diego hotels, so you can put your leftover money toward spending a day at the San Diego Zoo or seeing a show at the Civic Theater. Whether you’re traveling alone, with your partner, or with the whole family in tow, Expedia has the perfect hotel for you. Don’t settle for lackluster lodgings, and instead choose the hotel that fits you and your getaway right here on Expedia.