Hotels near Central San Diego

See all 99 Hotels in Central San Diego
California Suites Hotel
California Suites Hotel

5415 Clairemont Mesa Blvd, San Diego 92117

2.0 out of 5.0
3.5 out of 5 (2,924 reviews)

This 2-story hotel is centrally located less than 13 miles from the Gaslamp Quarter and several local beaches.

$64
Courtyard by Marriott San Diego Central
Courtyard by Marriott San Diego Central

8651 Spectrum Center Blvd, San Diego 92123

3.0 out of 5.0
4.3 out of 5 (614 reviews)

Situated in the business district, this hotel is within 6 mi (10 km) of Qualcomm Stadium, University of San Diego, and Fashio …

$134
Extended Stay America San Diego - Sorrento Mesa
Extended Stay America San Diego - Sorrento Mesa

9880 Pacific Heights Blvd, San Diego 92121

2.5 out of 5.0
3.1 out of 5 (397 reviews)

Extended Stay America San Diego - Sorrento Mesa is 15 minutes from Torrey Pines Golf Course, Marine Corps Air Station Miramar …

$103
Motel 6 San Diego North
Motel 6 San Diego North

5592 Clairemont Mesa Blvd, San Diego 92117

2.0 out of 5.0
3.3 out of 5 (183 reviews)

Situated near the airport, this motel is within 9 mi (15 km) of Fashion Valley Mall, La Jolla Cove, and University of San …

$66
Mission Valley Resort
Mission Valley Resort

875 Hotel Cir South, San Diego 92108

2.5 out of 5.0
2.4 out of 5 (3,804 reviews)

Comprising 8 buildings in a tropical setting near the foothills of Mission Valley, and convenient to I-8, this resort is 2 …

$57
Wyndham San Diego Bayside
Wyndham San Diego Bayside

1355 N Harbor Drive, San Diego 92101

3.5 out of 5.0
3.9 out of 5 (4,973 reviews)

Just west of the downtown core, this San Diego hotel is across the street from the cruise ship terminal, Coronado ferry, an …

$135
Urban Boutique Hotel
Urban Boutique Hotel

1654 Columbia Street, San Diego 92101

3.0 out of 5.0
3.9 out of 5 (2,013 reviews)

Situated in San Diego, this hotel is within a 15-minute walk of Firehouse Museum and Maritime Museum of San Diego. USS Midway …

$99
Humphreys Half Moon Inn
Humphreys Half Moon Inn

2303 Shelter Island Dr, San Diego 92106

3.5 out of 5.0
4.2 out of 5 (4,195 reviews)

Humphreys Half Moon Inn sits on 14 acres adjacent to a yacht-filled marina overlooking San Diego Bay.

$138
Hilton San Diego Mission Valley
Hilton San Diego Mission Valley

901 Camino Del Rio S, San Diego 92108

4.0 out of 5.0
3.9 out of 5 (2,410 reviews)

This 14-story hotel is just off I-8, within a few minutes from Mission Valley malls, Balboa Park and Old Town San Diego; …

$136
Ramada San Diego North Hotel and Conference Center
Ramada San Diego North Hotel and Conference Center

5550 Kearny Mesa Rd, San Diego 92111

3.0 out of 5.0
3.7 out of 5 (2,825 reviews)

Surrounded by palm trees, this hotel is situated on 5 acres of land, 9 miles from La Jolla beaches, 8 miles from the San Dieg …

Get Rates
Hide content

Where To Stay In Central San Diego

Central San Diego, San Diego Hotel Information

Expedia.com offers a selection of 99 hotels in Central San Diego. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs.

Expedia.com will not only save you time, but also money when booking your stay at a hotel in Central San Diego. Making reservations so you can stay within your budget is easy with us.

Expedia.com even provides you with a map so you may find hotels in the Central San Diego neighborhood you prefer.

Go ahead. Enter your travel dates to view the best offers on hotel rooms in Central San Diego, California now!

Looking for local hotels nearby? Check out the new hotels near me page.

These areas in SoCal will welcome you like a local. Feast on fresh homemade pasta in Little Italy, check out the Padres Petco Park stadium in East Village, or stroll along the harbor and check out the Star of India within easy access of your hotel. No matter what part of Central San Diego you wish to explore, Expedia has the right accommodations for you. From family-friendly suites with pool access for the kiddos to romantic hotels to spend a getaway with your sweetheart, you’ll find it all here.

Score the lowest rates on hotels in Central San Diego when you browse our selection. You’ll also find the hottest discounts on Downtown San Diego hotels, so you can put your leftover money toward spending a day at the San Diego Zoo or seeing a show at the Civic Theater. Whether you’re traveling alone, with your partner, or with the whole family in tow, Expedia has the perfect hotel for you. Don’t settle for lackluster lodgings, and instead choose the hotel that fits you and your getaway right here on Expedia.