Find spa resorts & hotels in MoJo, San Luis Obispo from $144

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Our top choices for MoJo hotels with a spa

Madonna Inn

Madonna Inn
3.5 star property
San Luis Obispo
9.2 out of 10, Wonderful, (1327)
"We love this place!"
United States
Jennifer
$164 nightly
The price is $187
Jan 4 - Jan 5, 2026
Total with taxes and fees
Madonna Inn

Avila Village Inn

Avila Village Inn
3.5 star property
Avila Beach
9.2 out of 10, Wonderful, (1001)
"The property and rooms were beautiful! We really enjoyed our weekend here and are planning to stay again!"
United States
Cathy
$153 nightly
The price is $173
Dec 16 - Dec 17
Total with taxes and fees
Avila Village Inn

The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection
2.5 star property
Arroyo Grande
9.6 out of 10, Exceptional, (1004)
"This is a wonderful place to stay. Beautiful interior, cozy common area, nice people, ideal location. "
United States
Michael
$127 nightly
The price is $144
Dec 19 - Dec 20
Total with taxes and fees
The Agrarian Hotel, BW Signature Collection

HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection
4.0 star property
Downtown San Luis Obispo
9.2 out of 10, Wonderful, (468)
"We had a great stay"
United States
ADALBERT
$214 nightly
The price is $243
Dec 18 - Dec 19
Total with taxes and fees
HOTEL CERRO, Autograph Collection

Cayucos Sunset Inn B&B

Cayucos Sunset Inn B&B
3.5 star property
Cayucos
9.8 out of 10, Exceptional, (195)
"Great place to stay"
United States
Jason
$156 nightly
The price is $176
Dec 15 - Dec 16
Total with taxes and fees
Cayucos Sunset Inn B&B

Inn at Rose's Landing

Inn at Rose's Landing
2.0 star property
Downtown Morro Bay
10.0 out of 10, Exceptional, (1)
"This little hotel is such a gem right on the bay! From the moment we arrived, it felt like we were staying in the shadow of Morro Rock. One of the best surprises was the wellness area — a sauna with therapy light and a cold plunge. Totally unexpected and such a cool touch. Our room wasn’t directly on the water, but it hardly mattered. There’s a spacious patio with ocean and bay views, complete with tables where we brought our dinner (partly covered by the free gift certificate we were handed at...
United States
Steven
$189 nightly
The price is $216
Dec 15 - Dec 16
Total with taxes and fees
Inn at Rose's Landing

Sea Pines Resort

Sea Pines Resort
3.0 star property
Los Osos
8.2 out of 10, Very Good, (410)
"Nice staff."
United States
Ann
$151 nightly
The price is $170
Dec 17 - Dec 18
Total with taxes and fees
Sea Pines Resort

Avila La Fonda Hotel

Avila La Fonda Hotel
4.0 star property
Avila Beach
9.6 out of 10, Exceptional, (1000)
"Very nice hotel. Great for and rest and relaxation kind of vacation"
United States
Princess
$185 nightly
The price is $209
Dec 15 - Dec 16
Total with taxes and fees
Avila La Fonda Hotel

Hotel San Luis Obispo

Hotel San Luis Obispo
4.5 star property
Downtown San Luis Obispo
9.4 out of 10, Exceptional, (548)
"Beautiful room and nice rooftop bar!"
United States
Chizuru
$296 nightly
The price is $336
Dec 15 - Dec 16
Total with taxes and fees
Hotel San Luis Obispo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about MoJo

Top MoJo attractions for a relaxing vacation

In the vibrant MoJo neighborhood, travelers seeking relaxation and indulgence will find a host of activities that perfectly complement a stay at spa hotels. Begin your day with a refreshing yoga session at the local Zen Garden, where the morning sun filters through lush greenery, setting a tranquil tone for your getaway. Afterward, treat yourself to a rejuvenating massage at one of MoJo's top-rated wellness centers, known for their expert therapists and serene ambiance. For a touch of culture, explore the nearby MoJo Art District, filled with captivating galleries showcasing local artists. If you're in the mood for some retail therapy, the boutique shops along Main Street offer unique finds that make perfect souvenirs. Finally, wrap up your evening with a gourmet dinner at a farm-to-table restaurant, where you can savor exquisite dishes made from locally sourced ingredients. Staying in one of MoJo's spa hotels means you can enjoy luxurious amenities such as rooftop pools and rejuvenating spa treatments just steps from your room, allowing you to unwind and recharge in style after a day of exploration.

Top MoJo Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in MoJo?
Treat yourself to some pampering and book a hotel with a spa. Spa hotels are the perfect way to break away from your routine and add a layer of luxury to your vacation.
What's there to see and do in MoJo?
Enjoy all that MoJo has to offer when you visit Fremont Theater, Mission San Luis Obispo de Tolosa, and Downtown SLO Farmers' Market. If you have extra time while you're in the area, you might want to stop by Performing Arts Center and Madonna Plaza Shopping Center.
What is a MoJo spa hotel?
Spa hotels in MoJo provide lodging and have an on-site spa offering services like massages and body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

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