Title: TOP 10 Hotels in St Mary, MO from $64 - Competitive Prices | Expedia.com [St Mary Travel Guide](https://expedia.com/St-Mary.dx3000445480)[Vacation Rentals in St Mary](https://expedia.com/St-Mary-Vacation-Rentals.d3000445480.Travel-Guide-VacationRentals)[Flights to St Mary](https://expedia.com/Cheap-Flights-To-St-Mary.d3000445480.Travel-Guide-Flights)[Car Rentals in St Mary](https://expedia.com/Car-Rentals-In-St-Mary.d3000445480.Car-Rental-Guide)[St Mary Vacation Packages](https://expedia.com/St-Mary.d3000445480.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in St Mary Family friendly [](https://www.expedia.com/Hotel-Search?destination=St+Mary%2C+Missouri%2C+United+States+of+America®ionId=3000445480&latLong=37.878941%2C-89.94928&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&travelerType=family_friendly) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=St+Mary%2C+Missouri%2C+United+States+of+America®ionId=3000445480&latLong=37.878941%2C-89.94928&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&amenities=PETS) Pool [](https://www.expedia.com/Hotel-Search?destination=St+Mary%2C+Missouri%2C+United+States+of+America®ionId=3000445480&latLong=37.878941%2C-89.94928&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&amenities=POOL) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=St+Mary%2C+Missouri%2C+United+States+of+America®ionId=3000445480&latLong=37.878941%2C-89.94928&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&lodging=APARTMENT) ## Check prices for these dates Tonight [Mar 26 - Mar 27](https://www.expedia.com/Hotel-Search?regionId=3000445480&startDate=2026-03-26&endDate=2026-03-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 27 - Mar 28](https://www.expedia.com/Hotel-Search?regionId=3000445480&startDate=2026-03-27&endDate=2026-03-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=3000445480&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=3000445480&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for St Mary hotels ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/2b5bb07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/ab22ad5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG [](https://www.expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) Perryville 9.2/10 Wonderful (571 reviews) "The hotel and room were very clean. It was in a quiet area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alice $95 nightly $109 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/ef8850d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/badbf4c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) Perryville 8.4/10 Very Good (969 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doug $65 nightly $75 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted tub](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/19091438.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/ddade665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/f64e14c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/333ae023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Chester IL [](https://www.expedia.com/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information) Chester 8.6/10 Excellent (371 reviews) "The room was spotless, very nice. Only problem i had was the microwave in the room did not work. Front desk lady was super nice, highly recommend" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) D'anna $74 nightly $82 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1430000/1429500/1429479/d4bc56bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1430000/1429500/1429479/c44a2fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/2000000/1430000/1429500/1429479/474450fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1430000/1429500/1429479/83886d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crown Pointe Lodge, BW Signature Collection [](https://www.expedia.com/Farmington-Hotels-Crown-Pointe-Lodge.h1429479.Hotel-Information) Farmington 9.0/10 Wonderful (600 reviews) "Excellent staff and location was nice and quiet " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen $110 nightly $125 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Crown-Pointe-Lodge.h1429479.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/105000000/104320000/104319800/104319742/d891a6b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Room | Private kitchen | Fridge, microwave, paper towels, dining tables](https://images.trvl-media.com/lodging/105000000/104320000/104319800/104319742/3eb49477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Room | Bathroom | Rainfall showerhead, hair dryer, towels, soap](https://images.trvl-media.com/lodging/105000000/104320000/104319800/104319742/6a6daf4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104320000/104319800/104319742/b26d249a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Bud Country Inn [](https://www.expedia.com/Red-Bud-Hotels-Red-Bud-Country-Inn.h104319742.Hotel-Information) Red Bud 9.0/10 Wonderful (59 reviews) "Plenty of free parking and very clean. Extremely nice hosts. Was listed under St. Louis but is really 50 minutes south. Free breakfast but minimal." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karissa $85 nightly $95 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/Red-Bud-Hotels-Red-Bud-Country-Inn.h104319742.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/db122c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/5f391186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/bca42102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/622c9d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madison Inn Lodge [](https://www.expedia.com/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) Fredericktown 7.6/10 Good (298 reviews) "Friendly staff, and pricing, accommodating to our pets" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlotte $88 nightly $96 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/8cca20e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/63c45b75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/e2a51dca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont Inn and Suites by Wyndham Farmington, MO [](https://www.expedia.com/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) Farmington 8.0/10 Very Good (1,009 reviews) "Great staff and nice accommodations " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa $58 nightly $66 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Classic Room, 1 King Bed | Down comforters, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/700000/692700/692668/d1c4344d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/700000/692700/692668/372ece1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/700000/692700/692668/d669a1ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room, 1 King Bed | Bathroom | Free toiletries, hair dryer, towels, soap](https://images.trvl-media.com/lodging/1000000/700000/692700/692668/20209c7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Briarwood Inn of Sparta [](https://www.expedia.com/Chester-Hotels-Briarwood-Inn-Of-Sparta.h692668.Hotel-Information) Sparta 7.6/10 Good (128 reviews) "Amazingly convenient for visiting pilots. A 5-minute walk across the highway. Clean, comfortable room with good fast-food options nearby. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel $69 nightly $77 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Chester-Hotels-Briarwood-Inn-Of-Sparta.h692668.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/4000000/3600000/3594600/3594547/000af9b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, laptop workspace](https://images.trvl-media.com/lodging/4000000/3600000/3594600/3594547/0029d3d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, laptop workspace](https://images.trvl-media.com/lodging/4000000/3600000/3594600/3594547/w3839h2584x0y3-9df926a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3600000/3594600/3594547/3db90f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Farmington [](https://www.expedia.com/Farmington-Hotels-Hampton-Inn-Farmington.h3594547.Hotel-Information) Farmington 8.8/10 Excellent (538 reviews) "Room was nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristina $114 nightly $130 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Hampton-Inn-Farmington.h3594547.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/d4a93b47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/ebca14b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/b6c1f98e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/61c8f623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy [](https://www.expedia.com/French-Village-Hotels-Postcard-Cabins-St-Francois.h110550817.Hotel-Information) French Village 9.8/10 Exceptional (57 reviews) "Beautiful , comfortable!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Taniyah $124 nightly $134 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/French-Village-Hotels-Postcard-Cabins-St-Francois.h110550817.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/331aa35f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/2635c5bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/93f13efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/456e3083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Sparta by IHG [](https://www.expedia.com/Chester-Hotels-Holiday-Inn-Express-Hotel-Suites-Sparta.h1691121.Hotel-Information) Sparta 9.2/10 Wonderful (384 reviews) "Great place! And excellent stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Casey $107 nightly $119 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Chester-Hotels-Holiday-Inn-Express-Hotel-Suites-Sparta.h1691121.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/e565804d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/32ba7ac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/e188e0c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/d7244881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Farmington [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information) Farmington 8.0/10 Very Good (630 reviews) "Friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Faith $60 nightly $68 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/430000/426000/425932/96e79bac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/426000/425932/46991f0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/430000/426000/425932/475e9554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/430000/426000/425932/d63c0a0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Sainte Genevieve [](https://www.expedia.com/Ste-Genevieve-Hotels-Microtel-Inn-Suites-By-Wyndham-Sainte-Genevieve.h425932.Hotel-Information) Ste Genevieve 8.8/10 Excellent (627 reviews) "Great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenneth $81 nightly $90 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Ste-Genevieve-Hotels-Microtel-Inn-Suites-By-Wyndham-Sainte-Genevieve.h425932.Hotel-Information) ![Room, 1 King Bed | Jetted tub](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/6caf4858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/e7849830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/19d8e2e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Perryville [](https://www.expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) Perryville 6.8/10 (428 reviews) "Parking was easy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Binggang $71 nightly $82 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/a262c28f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/354a7163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/2880668c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mississippi Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/b9242bc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Conner House B&B [](https://www.expedia.com/Chester-Hotels-The-Conner-House-Bed-And-Breakfast.h34893294.Hotel-Information) Prairie du Rocher 10/10 Exceptional (19 reviews) "Wonderful folks that work there. Nice b&b in a quiet , scenic area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bradley $136 nightly $151 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Chester-Hotels-The-Conner-House-Bed-And-Breakfast.h34893294.Hotel-Information) ![Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/18500/18482/f915a7d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18500/18482/7fa09058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18500/18482/21afb20e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/20000/18500/18482/493a31ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Farmington [](https://www.expedia.com/Farmington-Hotels-Quality-Inn-Farmington.h18482.Hotel-Information) Farmington 7.6/10 Good (878 reviews) "Clean room no smells of smoke very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erica $56 nightly $64 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Quality-Inn-Farmington.h18482.Hotel-Information) ![Standard room, 2 double beds. | Blackout drapes, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/30000000/29380000/29373400/29373308/416a5c39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/30000000/29380000/29373400/29373308/41fbb4bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard room , 1 King bed. | Blackout drapes, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/30000000/29380000/29373400/29373308/3b572bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard room , 1 King bed. | Blackout drapes, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/30000000/29380000/29373400/29373308/72d26ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Triangle Inn Motel [](https://www.expedia.com/Perryville-Hotels-Triangle-Inn-Motel.h29373308.Hotel-Information) Ste Genevieve 8.0/10 Very Good (47 reviews) "The staff was very warm and welcoming. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom $76 nightly $85 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Triangle-Inn-Motel.h29373308.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/6b56391d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/0d3bba3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/26f852d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Perryville I-55 [](https://www.expedia.com/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) Perryville 6.6/10 (128 reviews) "satisfactory" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $80 nightly $92 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/804f0425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/2cb1c224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/9e44784b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed with Sofa bed, Pets Allowed | Interior](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/d395df9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Atrium - A Boutique Hotel [](https://www.expedia.com/Perryville-Hotels-The-Atrium-A-Boutique-Hotel.h126617355.Hotel-Information) Perryville $133 nightly $152 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-The-Atrium-A-Boutique-Hotel.h126617355.Hotel-Information) ![Free self parking](https://images.trvl-media.com/lodging/12000000/11250000/11249000/11249000/e56d8669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11250000/11249000/11249000/3b9145b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Double Bed | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11250000/11249000/11249000/0bdd5e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/12000000/11250000/11249000/11249000/1d46161a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capital O Sparta Motel Near Carbondale [](https://www.expedia.com/Chester-Hotels-Sparta-Motel.h11249000.Hotel-Information) Sparta 4.4/10 (67 reviews) "Nice hotel, clean, huge pool" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacey $77 nightly $85 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/Chester-Hotels-Sparta-Motel.h11249000.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-09&endDate=2026-04-10®ionId=3000445480&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSt-Mary-Hotels.d3000445480.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSt-Mary-Hotels.d3000445480.Travel-Guide-Hotels) ## Top St Mary Hotel Reviews ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08_y.jpg) ### Super 8 by Wyndham Perryville 8/10 Good "When we first checked in they put us in 117 which had a puddle of water in the floor by the front door and bathroom. After checking with staff we found out there was a leak coming from the roof and wall in the bathroom they later told us there was an issue with something on the top level. I wasn't really happy with this because they allowed us to check into that room and had to move us to another room across the hall and had to wait around 10 minutes." [](https://expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Crown Pointe Lodge, BW Signature Collection](https://images.trvl-media.com/lodging/2000000/1430000/1429500/1429479/d4bc56bb_y.jpg) ### Crown Pointe Lodge, BW Signature Collection 6/10 Okay "Overall it was okay, we’ve stayed here for years but it has changed owners and with that different management. Staff takes all the upfront parking including the manager. Parking in the handicap striped space that’s suppose to allow cars with handicap tags the ability to open their doors fully or use a wheelchair ramp. When I confronted her with it she saw no problem with her continuing to park there. She was very rude during most of our interactions while we stayed there. Not sure we will ever go back. Very disappointing. " [](https://expedia.com/Farmington-Hotels-Crown-Pointe-Lodge.h1429479.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6_y.jpg) ### Holiday Inn Express & Suites Perryville by IHG 10/10 Excellent "The young man who was at the check in desk has the best manners, super polite, kind and efficient. It was very nice to be welcomed by him!!! " [](https://expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Days Inn by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/6caf4858_y.jpg) ### Days Inn by Wyndham Perryville 4/10 Poor "When we got to our room, it was open and not cleaned...at 9pm! Got another room....while it appeared to have been cleaned, ready for customers...the floor was carpet and chunks of debri on it, headboard had footprints and handprints on it, shower curtain was torn and dirty, the tv remote did not work and breakfast was a joke. Staff was ok, not rude just not very customer service type and looked about 12\. " [](https://expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Briarwood Inn of Sparta](https://images.trvl-media.com/lodging/1000000/700000/692700/692668/d1c4344d_y.jpg) ### Briarwood Inn of Sparta 6/10 Okay "Nobody on staff late night, had to ring bell. Smell of Thau food constantly, not much of a breakfast. No spoons, knives, forks, three cups, no coffee throughout the day, and no napkins. " [](https://expedia.com/Chester-Hotels-Briarwood-Inn-Of-Sparta.h692668.Hotel-Information) ![Baymont Inn and Suites by Wyndham Farmington, MO](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/8cca20e5_y.jpg) ### Baymont Inn and Suites by Wyndham Farmington, MO 10/10 Excellent "As Good As It Gets Folks. Great Value For Your Money. Clean Comfortable Room. Friendly Staff." [](https://expedia.com/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Holiday Inn Express Hotel & Suites Sparta by IHG](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/331aa35f_y.jpg) ### Holiday Inn Express Hotel & Suites Sparta by IHG 6/10 Okay "Yes" [](https://expedia.com/Chester-Hotels-Holiday-Inn-Express-Hotel-Suites-Sparta.h1691121.Hotel-Information) ![Baymont by Wyndham Chester IL](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/19091438_y.jpg) ### Baymont by Wyndham Chester IL 6/10 Okay " When I arrived no one was at front desk and receptionist didn't arrive until 10 min later from running an errand and noone seemed to be around to say she was out nor was there a sign to indicate will return soon. Room had bugs crawling in window seal, I was offered a new room further away. " [](https://expedia.com/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information) ![Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops.](https://images.trvl-media.com/lodging/97000000/96360000/96356100/96356094/cdbfd164_y.jpg) ### Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops. 10/10 Excellent "The house was very clean. It's located in a quiet and safe neighborhood. It was well stocked with cooking utensils. It was pet friendly with a secure fenced backyard. The host was responsive and accommodating. We stayed here while we were in town for work and would stay here again." [](https://expedia.com/St-Mary-Hotels-Ste-Genevieve-Co-House-W-HOT-TUB.h96356094.Hotel-Information) ## More cheap stays in St Mary ![Baymont Inn and Suites by Wyndham Farmington, MO](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/8cca20e5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont Inn and Suites by Wyndham Farmington, MO 1625 W Columbia St Farmington MO $58 nightly $66 total Apr 5 - Apr 6 Total with taxes and fees 8/10 Very Good! (1,009 reviews) [](https://expedia.com/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Baymont by Wyndham Chester IL](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/19091438_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Chester IL 2150 State Street Chester IL $74 nightly $82 total Apr 5 - Apr 6 Total with taxes and fees 8.6/10 Excellent! (371 reviews) [](https://expedia.com/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information) ![Microtel Inn & Suites by Wyndham Sainte Genevieve](https://images.trvl-media.com/lodging/1000000/430000/426000/425932/96e79bac_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Microtel Inn & Suites by Wyndham Sainte Genevieve 21958 Hwy 32 Ste Genevieve MO $81 nightly $90 total Mar 29 - Mar 30 Total with taxes and fees 8.8/10 Excellent! (627 reviews) [](https://expedia.com/Ste-Genevieve-Hotels-Microtel-Inn-Suites-By-Wyndham-Sainte-Genevieve.h425932.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Perryville by IHG 2020 Jefferson St Perryville MO $95 nightly $109 total Mar 29 - Mar 30 Total with taxes and fees 9.2/10 Wonderful! (571 reviews) [](https://expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Holiday Inn Express Hotel & Suites Sparta by IHG](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/331aa35f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Sparta by IHG 1301 N Market St Sparta IL $107 nightly $119 total Apr 5 - Apr 6 Total with taxes and fees 9.2/10 Wonderful! (384 reviews) [](https://expedia.com/Chester-Hotels-Holiday-Inn-Express-Hotel-Suites-Sparta.h1691121.Hotel-Information) ![Crown Pointe Lodge, BW Signature Collection](https://images.trvl-media.com/lodging/2000000/1430000/1429500/1429479/d4bc56bb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Crown Pointe Lodge, BW Signature Collection 4245 Hunt Rd Farmington MO $110 nightly $125 total Apr 1 - Apr 2 Total with taxes and fees 9/10 Wonderful! (600 reviews) [](https://expedia.com/Farmington-Hotels-Crown-Pointe-Lodge.h1429479.Hotel-Information) ## Hotels in St Mary with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.com/4Star-St-Mary-Hotels.s40-0-d3000445480.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 9 properties [](https://expedia.com/3Star-St-Mary-Hotels.s30-0-d3000445480.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 37 properties [](https://expedia.com/2Star-St-Mary-Hotels.s20-0-d3000445480.Travel-Guide-Filter-Hotels) ## Find out more about St Mary ### Top reasons to visit St Mary - **Outdoor Adventures:** St. Mary offers a range of outdoor activities, perfect for nature lovers and adventure seekers. - **Charming Neighborhoods:** Explore friendly local communities that provide a warm welcome and unique experiences. - **Historic Sites:** Discover the area's rich culture through its museums and historic landmarks. - **Scenic St Marys River:** Enjoy the picturesque views and recreational opportunities along the river. - **Variety of Accommodations:** Choose from cozy motels to welcoming hotels, catering to all types of travelers. ### Find great hotels near St Mary Discover a variety of lodging options in St. Mary, Missouri, perfect for every traveler. Whether you're seeking a cozy motel or a welcoming hotel, you'll find pet-friendly accommodations and amenities tailored for business and adventure seekers alike. With convenient locations near St. Mary, you can easily explore the charming surroundings while enjoying a comfortable stay. Experience the best of St. Mary's hospitality and make your vacation unforgettable. - **[Super 8 by Wyndham Perryville: ](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information)** This budget-friendly motel offers a convenient stay with a guest rating of 8.4, making it an appealing option for both business and leisure travelers. Located 12 miles from St Mary, Super 8 by Wyndham Perryville is known for its pet-friendly policies, allowing you to bring your furry friends along for the trip. With amenities like free Wi-Fi, complimentary breakfast, and a business center, it caters to all your travel needs while ensuring comfort and convenience. - **[Holiday Inn Express & Suites Perryville by IHG: ](https://www.expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information)** Rated 9.2, this hotel combines modern amenities with a welcoming atmosphere, ideal for business travelers. Situated 12 miles from St Mary, it features spacious rooms equipped with flat-screen TVs, a fitness center, and a complimentary breakfast bar to kickstart your day. The Holiday Inn Express & Suites is designed for convenience, making it a top choice for those seeking a reliable and comfortable stay in the area. - **[Baymont by Wyndham Chester IL: ](https://www.expedia.com/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information)** Located 8 miles from St Mary, Baymont by Wyndham Chester IL is another excellent budget option with a guest rating of 8.6\. This hotel is also pet-friendly, allowing dogs to join in on your travels. Guests enjoy amenities such as free Wi-Fi, an indoor pool, and a complimentary breakfast. Its warm atmosphere and accommodating staff make it a perfect choice for both business and leisure travelers looking for a comfortable stay. ### Where to stay near St Mary St. Mary, Missouri, offers a delightful blend of outdoor adventures and romantic getaways. Explore the charming neighborhoods where friendly locals welcome you with warmth. Just minutes from campus, enjoy family-friendly activities and excursions that highlight the area's natural beauty. Venture out to nearby attractions for a perfect coastal getaway or simply unwind in the serene atmosphere that St. Mary provides. Whether you seek adventure or relaxation, this destination has something for everyone. - **[Ste Genevieve: ](https://www.expedia.com/Ste-Genevieve-Hotels.d183502.Travel-Guide-Hotels)** Located 9 miles from St. Mary, Ste Genevieve is known for its charming blend of outdoor and romantic experiences. The city welcomes travelers year-round, with peak visits occurring from July to September. Visitors can enjoy the local recreational areas and campgrounds, perfect for a weekend getaway. Notable attractions nearby include a national state park and a picturesque lake, ideal for hiking, fishing, and enjoying nature. Events and conferences are also hosted here, making Ste Genevieve a great destination for both leisure and business travelers. - **[Perryville: ](https://www.expedia.com/Perryville-Hotels.d6134448.Travel-Guide-Hotels)** Situated 11 miles away from St. Mary, Perryville is a delightful city that attracts visitors seeking outdoor adventures and scenic views. The travel season peaks from June to August, drawing those looking for summer fun. Popular venues include an amusement park and an arcade adventure zone, making it a family-friendly destination. Nearby, visitors can explore the natural beauty of a national state park and relax at a serene lake. Perryville’s combination of outdoor activities and romantic spots makes it a great choice for all types of travelers. - **[Chester: ](https://www.expedia.com/Chester-Hotels.d6139861.Travel-Guide-Hotels)** Just 7 miles from St. Mary, Chester is a vibrant city that offers outdoor enthusiasts a perfect blend of adventure and stunning scenery. The city experiences consistent visitor numbers throughout the year, with a peak in the summer months from June to August. Chester features recreational areas and campgrounds, allowing for a variety of outdoor pursuits. Local landmarks include a national state park and lush forests, ideal for hiking and wildlife observation. Chester’s natural beauty and adventure-filled atmosphere make it a must-visit destination. ### Things to do near St Mary St. Mary, Missouri, is an ideal destination for outdoor and romantic adventures, offering a variety of activities such as golfing and exploring recreational areas. Visitors can enjoy shopping experiences, discover local tourist attractions, and participate in city events, making it a perfect spot for relaxation and fun. Whether you're seeking leisure or excitement, St. Mary has something for everyone to enjoy. **Shopping** In St. Mary, you can enjoy local shops offering unique gifts and souvenirs. If you're up for a drive, visit the nearby Cape Girardeau Mall, which features a variety of retail stores, or explore the charming boutiques in downtown Cape Girardeau for more eclectic finds. **Recreation** [Sparta Country Club](https://www.expedia.com/Sparta-Country-Club-Hotels.0-l6187185-0.Travel-Guide-Filter-Hotels) offers a luxurious retreat 21 miles from St Mary, featuring pristine golf courses and elegant amenities. Enjoy a round of golf, unwind by the pool, or indulge in gourmet dining, all while soaking in the tranquil surroundings and upscale atmosphere for a rejuvenating experience. **Adventure** Explore the scenic trails at the nearby Mark Twain National Forest, perfect for hiking and mountain biking. Experience thrilling water activities on the Mississippi River, from kayaking to fishing, and soak in the charming local history at the nearby historic sites for a well-rounded adventure. **Nightlife** Experience the lively atmosphere at The Corner Pub, where you can enjoy local brews and friendly conversation. For a dance night, visit The Blue Moon Lounge, featuring live DJs and a vibrant crowd. Don't miss the outdoor movie nights at the City Park for a unique experience. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for St Mary - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in St Mary are January to February and November, where the prices are slightly lower. This is in comparison to April to May and July, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in St Mary is Wednesday. The most expensive day to stay in St Mary is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia's search tool to narrow down your options based on your budget, preferred location, and the type of hotel you desire. To find the best prices and deals, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your hotel stay in St. Mary with your flights and activities through an Expedia package deal. ### Find the best attractions near St Mary St Mary, Missouri, is perfect for outdoor enthusiasts and couples seeking adventure and romance. Explore the historic sites, urban parks, and local museums that showcase the area's rich culture. Don't miss the scenic St Marys River and the charming St Mary Village. Nearby attractions and the historic St Marys Museum provide additional family-friendly experiences, ensuring a memorable visit for all travelers. - **[Popeye Museum: ](https://www.expedia.com/Popeye-Museum-Hotels.0-l553248621532655787-0.Travel-Guide-Filter-Hotels)** Located only 7 miles from St. Mary, this charming museum celebrates the beloved cartoon character Popeye. Immerse yourself in the nostalgia of classic cartoons while exploring unique memorabilia, artwork, and exhibits that capture the spirit of this iconic sailor. - **[Fort Kaskaskia: ](https://www.expedia.com/Fort-Kaskaskia-Hotels.0-l6183800-0.Travel-Guide-Filter-Hotels)** Just 6 miles away, this historic site offers a glimpse into the past with its well-preserved structures and rich history. Explore the fort's grounds and learn about its role in early American history while enjoying scenic views of the Mississippi River. - **[Elzie C. Segar Memorial Park: ](https://www.expedia.com/Elzie-C-Segar-Memorial-Park-Hotels.0-l6183802-0.Travel-Guide-Filter-Hotels)** Situated 7 miles from St. Mary, this urban park is perfect for families and outdoor enthusiasts. Enjoy walking trails, picnic areas, and playgrounds, all while celebrating the legacy of Elzie C. Segar, the creator of Popeye. ### Best time to go to St Mary The best time to visit St Mary is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 32.9°F (0.5°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | | February | 36.0°F (2.2°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | | March | 46.9°F (8.3°C) | Light Rain | Mostly Sunny | Average | Average | | April | 56.1°F (13.4°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 66.0°F (18.9°C) | Light Rain | Mostly Sunny | Average | Slightly High | | June | 75.4°F (24.1°C) | Light Rain | Mostly Sunny | Slightly High | Average | | July | 78.1°F (25.6°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | August | 76.1°F (24.5°C) | Light Rain | Mostly Sunny | Slightly High | Average | | September | 70.2°F (21.2°C) | Light Rain | Mostly Sunny | Average | Average | | October | 58.5°F (14.7°C) | Light Rain | Mostly Sunny | Average | Average | | November | 46.0°F (7.8°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 38.1°F (3.4°C) | Light Rain | Mostly Sunny | Slightly Low | Average | ### The nearest major airports for your trip to St Mary Traveling to St. Mary, Missouri, is convenient with three major airports nearby. St. Louis Lambert International Airport ([STL](https://www.expedia.com/Lambert-St-Louis-Intl-Airport-Hotels.0-aSTL-0.Travel-Guide-Filter-Hotels)) is 64 miles away, with hotels like [The Ritz-Carlton](https://www.expedia.com/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information), St. Louis and [Ameristar Casino Resort and Spa](https://www.expedia.com/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information), both 7 miles from the airport. Cape Girardeau Municipal Airport ([CGI](https://www.expedia.com/Cape-Girardeau-Municipal-Airport-Hotels.0-aCGI-0.Travel-Guide-Filter-Hotels)) is 50 miles from St. Mary, offering options like Drury Plaza Hotel, just 6 miles away. Lastly, Williamson County Regional Airport ([MWA](https://www.expedia.com/Veterans-Airport-Of-Southern-Illinois-Airport-Hotels.0-aMWA-0.Travel-Guide-Filter-Hotels)) is 52 miles from St. Mary, with [Drury Inn & Suites Marion](https://www.expedia.com/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) located 2 miles from the airport. Each airport provides accessible transportation to nearby accommodations, making your visit seamless. ## Frequently asked questions ### What is the best area to stay in St Mary? > This area is the heart of St. Mary, characterized by its well-preserved 19th-century architecture and proximity to the Mississippi River. The main street, Market Street, features several local businesses and historic buildings, making it a pleasant area for a leisurely stroll. > > > Couples looking for a quiet getaway will appreciate this area. It offers a relaxed pace, with opportunities for scenic walks along the riverfront and visits to local historical markers. The downtown district provides a sense of stepping back in time, away from the hustle and bustle. > > > For those interested in local history and a peaceful environment, staying near the downtown historic district is ideal. ### When is the best time to go to St Mary? > Spring brings mild temperatures and blooming wildflowers, making it ideal for exploring the natural beauty of the area, particularly for those interested in hiking or birdwatching in the nearby state parks. The comfortable weather allows for enjoyable scenic drives along the Mississippi River. > > > Fall offers cooler temperatures and the vibrant colors of changing leaves, creating a picturesque setting for visitors. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a St Mary hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a St Mary hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Ozora Hotels ](https://www.expedia.com/Ozora-Hotels.d553248635975852499.Travel-Guide-Hotels) - [Ste Genevieve Hotels ](https://www.expedia.com/Ste-Genevieve-Hotels.d183502.Travel-Guide-Hotels) - [Hotels near Felix Valle House State Historic Site ](https://www.expedia.com/Felix-Valle-House-State-Historic-Site-Hotels.0-l553248621532648573-0.Travel-Guide-Filter-Hotels) - [Hotels near Sainte Genevieve Winery ](https://www.expedia.com/Sainte-Genevieve-Winery-Hotels.0-l553248621532648574-0.Travel-Guide-Filter-Hotels) - [B&B in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Bed-And-Breakfast.d183502-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Cabins.d183502-aaCabins.Travel-Guide-Accommodation) - 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