Top 10 Hotels in Fruitland, MO (from $67) 2026 - Competitive Prices

Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Learn about One Key
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Fruitland

Pet friendly

Apartment

Condo

Pool

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Fruitland hotels

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

A hotel room with two beds, a brick wall, and a wooden headboard.

1. Drury Inn & Suites Jackson MO

Jackson

Debra S

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

2. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Curtis

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

3. The Riverview

Cape Girardeau

Alyssa

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

An outdoor patio with tables and chairs, a stone wall, and large windows.

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

5. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Teresa

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

A hotel room with a bed, a TV, a desk, and a chair.

6. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

7. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Troy

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

8. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

Rebecca

A hotel room with two beds, a desk, a chair, a TV, and a projector screen.

A reception area with two reception desks, a wall-mounted sign, and a refrigerator.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

A buffet with various food items, including omelets and other dishes, with clear signage indicating the type of food.

9. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

Lauren

A modern retail area with a display of local items and snacks.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

10. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

11. Quality Inn Cape Girardeau North

Cape Girardeau

Dayanita

An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.

A spacious lobby with a central seating area, a large window, and a reception desk.

A hotel reception area with a wooden reception desk, a digital kiosk, and a refrigerated display case with beverages.

A modern kitchen with a stainless steel refrigerator, microwave, and dishwasher. There is a window providing natural light and a view of the outdoors.

12. Home2 Suites by Hilton Carbondale

Carbondale

Alyssa

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A lobby with seating areas, a reception desk, and a bar.

A spacious living room with a sofa set, a coffee table, and a dining area.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

13. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

14. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A hotel lobby with a seating area, a reception desk, and a bar.

A kitchen counter with a coffee machine, a kettle, and storage boxes.

A swimming pool with a diving board, pool rules signs, and lounge chairs.

15. Holiday Inn Express & Suites Perryville by IHG

Perryville

Lisa

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

16. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

17. Super 8 by Wyndham Perryville

Perryville

Matthew

A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.

A rustic building with a thatched roof, surrounded by dense greenery and a gravel path leading to it.

A cozy log cabin interior with a wooden staircase, a cushioned sofa, a small table, and a lamp.

A stone building with a patio area, string lights, and outdoor seating.

18. Makanda Inn

Makanda

Michele

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

19. Town House Inn

Jackson

Taylor

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

An outdoor patio with stone walls, wicker furniture, and large windows.

20. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Fruitland Hotel Reviews

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Room was clean and staff was very friendly"

Quality Inn Cape Girardeau North

10/10 Excellent

"All in all, wasn't too bad. Is time for some renovation."

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

10/10 Excellent

"The property is beautiful as well as the house. The property has enough trees for shade, it's i.e, not so heavily wooded that it's isolating. The owners and another family are close by and really helpful when we texted with a question. The hot tub is completely private and lit in the evening with soft lighting :). The grill is in the same area. The fire pit is on the other side by the dock. We woke early our last day to sit on the dock and watch the sunrise. The house … is oh so uniquely charming with a front and a side deck!!!!!! Each room is tastefully decorated and curated for a happy, fun, and welcome experience. Everything is stocked, easy to find, with house directions and suggestions for outings printed in a welcome binder, The town of Anna is 5 minutes away where we went to the Farmstead for hot/cold sandwiches with lots of delicious homemade amish selections/option for takeaway. We went to the newly opened HubBarn, a repurposed grocery store, that had 60 booths of new and thrift items - a real treasure. We will certainly be coming back to hike the beautiful sacred land of the Shawnee National Forest."

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"Nice property"

Drury Inn & Suites Jackson MO

10/10 Excellent

"We were only there for one night, but we SO grateful for a clean, safe and lovely stay! Would recommend it highly!"

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

10/10 Excellent

"Everything was perfect for a relaxing, romantic weekend away!"

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

Beautiful location in the secluded woods

8/10 Good

"It was good, except the A/C was in the living room and you need to keep the bedroom doors open to get the air."