Top 10 Hotels in Fruitland, MO (from $69) 2026 - Competitive Prices

Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Learn about One Key
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Fruitland

Pet friendly

Apartment

Condo

Pool

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Fruitland hotels

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

A hotel room with two beds, a brick wall, and a wooden headboard.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

1. Drury Inn & Suites Jackson MO

Jackson

Victor K

$82 nightly

$87 total

Sep 21 - Sep 22

Total with taxes and fees

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

2. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

$100 nightly

$113 total

Sep 13 - Sep 14

Total with taxes and fees

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern outdoor seating area with a glass-top table and a fire feature, overlooking a sunset view.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

3. The Riverview

Cape Girardeau

Alyssa

$104 nightly

$117 total

Oct 5 - Oct 6

Total with taxes and fees

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A hotel room with two beds, a nightstand, a lamp, and a chair.

An outdoor patio with tables and chairs, a stone wall, and large windows.

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

crystal

$93 nightly

$100 total

Sep 6 - Sep 7

Total with taxes and fees

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

5. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Cheryl

$90 nightly

$102 total

Sep 13 - Sep 14

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a projector screen.

A Holiday Inn Express & Suites hotel with a modern building facade, a covered entrance, and a landscaped lawn.

An indoor swimming pool with four lounge chairs and a metal ladder.

A reception area with two reception desks, a wall-mounted sign, and a refrigerator.

6. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

justin

$118 nightly

$131 total

Sep 9 - Sep 10

Total with taxes and fees

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

A multi-story hotel with a mix of brick and red facade, featuring a Holiday Inn Express sign.

7. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

$101 nightly

$115 total

Sep 7 - Sep 8

Total with taxes and fees

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

8. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Raidas

$72 nightly

$81 total

Sep 13 - Sep 14

Total with taxes and fees

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

9. Quality Inn Cape Girardeau North

Cape Girardeau

Stephen

$61 nightly

$69 total

Oct 4 - Oct 5

Total with taxes and fees

A modern retail area with a display of local items and snacks.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

10. Tru By Hilton Cape Girardeau

Cape Girardeau

Darlene

$89 nightly

$102 total

Sep 20 - Sep 21

Total with taxes and fees

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

An indoor swimming pool with clear water, tiled walls, and a metal ladder.

11. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

$82 nightly

$98 total

Oct 4 - Oct 5

Total with taxes and fees

An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.

A modern kitchen with a stainless steel refrigerator, microwave, and dishwasher. There is a window providing natural light and a view of the outdoors.

A spacious lobby with a central seating area, a large window, and a reception desk.

A hotel reception area with a wooden reception desk, a digital kiosk, and a refrigerated display case with beverages.

12. Home2 Suites by Hilton Carbondale

Carbondale

Alyssa

$121 nightly

$140 total

Sep 28 - Sep 29

Total with taxes and fees

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

13. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Chevonne

$101 nightly

$114 total

Sep 13 - Sep 14

Total with taxes and fees

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A lobby with seating areas, a reception desk, and a bar.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

14. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

$125 nightly

$142 total

Sep 20 - Sep 21

Total with taxes and fees

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

15. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

$80 nightly

$86 total

Oct 4 - Oct 5

Total with taxes and fees

A Holiday Inn Express & Suites building with a covered entrance and multiple windows.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a ceiling with recessed lighting.

A modern dining area with high tables and chairs, a television screen, and a view of the outdoors through large windows.

A hotel room with a large bed, a desk with a computer, a TV, and a seating area with a chair and a sofa.

16. Holiday Inn Express & Suites Perryville by IHG

Perryville

David

$91 nightly

$104 total

Oct 4 - Oct 5

Total with taxes and fees

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

17. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

$106 nightly

$119 total

Sep 13 - Sep 14

Total with taxes and fees

A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.

A cozy living room with a brown leather sofa, a wooden coffee table, and a window with a view of trees.

A rustic building with a thatched roof, surrounded by dense greenery and a gravel path leading to it.

A cozy log cabin interior with a wooden staircase, a cushioned sofa, a small table, and a lamp.

18. Makanda Inn

Makanda

Michele

$246 nightly

$272 total

Sep 6 - Sep 7

Total with taxes and fees

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

19. Super 8 by Wyndham Perryville

Perryville

Elizabeth

$71 nightly

$81 total

Sep 13 - Sep 14

Total with taxes and fees

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

20. Town House Inn

Jackson

Taylor

$88 nightly

$95 total

Sep 6 - Sep 7

Total with taxes and fees

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Fruitland Hotel Reviews

Drury Inn & Suites Jackson MO

10/10 Excellent

"Great space. The property is well kept. Breakfast was very good. Staff was pleasant. Very pleased"

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Clean room friendly staff"

Tru By Hilton Cape Girardeau

10/10 Excellent

"Clean, quiet - and EV chargers both on and adjacent (Tesla Supercharger) to hotel property."

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Room was clean. Bed was a very comfortable best pillows We’ve had the whole trip . close to several different places to eat."

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"This location is a must stay any time I am traveling in the area. The staff are helpful. There are lots of dinning options near by. I can always count on a peaceful night sleep at this location."

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

10/10 Excellent

"This place was an instant favorite! I absolutely LOVED the decor!! Everything was very clean and maintained, and you can tell by the attention to detail that this lodge is very well cared for. All of the furniture and beds were very comfortable! I love that there was plenty of space on each level so that if you have extra guests, everyone has plenty of room (just be sure to stick the tall folks downstairs, the clearance is a bit short when coming down the stairs from the upper level). The basement area was super spacious and had the cutest decorations (I LOVE the retro carpet in the kitchen!) The hosts even had a booklet with the history of the lodge and pictures from when it belonged to their beloved Grandma. This lodge is pretty close to alot of amenities and things to do, but still far out enough to give that rural, private feel. I can't wait until we come back, and we'll stay a couple of extra nights next time!!"

Beautiful location in the secluded woods

10/10 Excellent

"Stayed two years in a row - excellent."

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"Beautiful nice clean place. Beds are so comfortable too! Just wished they offered breakfast"

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

10/10 Excellent

"This is a beautiful and serene property! Tanya and John have made every effort to make this cabin as relaxing as any 5 star resort-except no crowds or screaming kids! lolWe booked early and communication was great throughout the whole process. The cabin is lovely-all the perfect amenities to make a comfy stay. We ate breakfast on the screened porch, spent time by the water, saw a host of beautiful birds and even heard the donkey from across the pond! The canine is air conditioned, and although we didn’t have time to use the hot tub, we hope to book again for exactly that reason! Check-in and check out were super easy. We wanted for nothing during our stay, and left relaxed and happy! Thank you so much!"

More cheap stays in Fruitland