Top 10 Hotels in Pocahontas, MO (from $67) 2026 - Competitive Prices

Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Learn about One Key
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Pocahontas

Pet friendly

Apartment

Condo

Pool

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Pocahontas hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Crystal

$100 nightly

$113 total

Oct 8 - Oct 9

Total with taxes and fees

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

2. The Riverview

Cape Girardeau

Brian

$99 nightly

$112 total

Oct 5 - Oct 6

Total with taxes and fees

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

A hotel room with two beds, a brick wall, and a wooden headboard.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

3. Drury Inn & Suites Jackson MO

Jackson

Thomas

$80 nightly

$85 total

Oct 8 - Oct 9

Total with taxes and fees

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

4. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Rex

$92 nightly

$104 total

Oct 11 - Oct 12

Total with taxes and fees

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

5. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Katrinia

$85 nightly

$101 total

Oct 11 - Oct 12

Total with taxes and fees

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

6. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Teresa

$81 nightly

$87 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

7. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Sharon

$72 nightly

$81 total

Oct 11 - Oct 12

Total with taxes and fees

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

8. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

Michael

$101 nightly

$115 total

Oct 11 - Oct 12

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a projector screen.

An indoor swimming pool with four lounge chairs and a metal ladder.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

A reception area with two reception desks, a wall-mounted sign, and a refrigerator.

9. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

Shirley

$101 nightly

$112 total

Nov 1 - Nov 2

Total with taxes and fees

An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.

A hotel with a covered entrance, outdoor seating, and a flag.

A spacious lobby with a central seating area, a large window, and a reception desk.

A modern kitchen with a stainless steel refrigerator, microwave, and dishwasher. There is a window providing natural light and a view of the outdoors.

10. Home2 Suites by Hilton Carbondale

Carbondale

Robert

$105 nightly

$121 total

Nov 1 - Nov 2

Total with taxes and fees

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A lobby with seating areas, a reception desk, and a bar.

A spacious living room with a sofa set, a coffee table, and a dining area.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

11. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

$125 nightly

$142 total

Oct 18 - Oct 19

Total with taxes and fees

A room with a brown sofa, a brown armchair, a patterned carpet, a lamp, and a window with curtains.

A hotel with a Super 8 sign, multiple parking spaces, and a brick facade.

A hotel lobby with a reception desk, several tables and chairs, framed pictures on the walls, and a clock.

A hotel room with a large bed, a desk, a chair, a window with curtains, a wall-mounted TV, and a large painting.

12. Super 8 by Wyndham Carbondale

Carbondale

Georgiana

$65 nightly

$75 total

Oct 4 - Oct 5

Total with taxes and fees

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

13. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Kelley

$101 nightly

$114 total

Oct 8 - Oct 9

Total with taxes and fees

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A kitchen counter with a coffee machine, a kettle, and storage boxes.

A swimming pool with a diving board, pool rules signs, and lounge chairs.

A buffet with various food items, including omelets and other dishes, served in metal containers with glass lids.

14. Holiday Inn Express & Suites Perryville by IHG

Perryville

Zenaida

$95 nightly

$109 total

Nov 1 - Nov 2

Total with taxes and fees

A modern retail area with a display of local items and snacks.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

15. Tru By Hilton Cape Girardeau

Cape Girardeau

Kaitlynn

$89 nightly

$102 total

Oct 11 - Oct 12

Total with taxes and fees

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

16. Quality Inn Cape Girardeau North

Cape Girardeau

Jim

$59 nightly

$67 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

17. Super 8 by Wyndham Perryville

Perryville

Joseph

$69 nightly

$79 total

Oct 11 - Oct 12

Total with taxes and fees

A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.

A rustic building with a thatched roof, surrounded by dense greenery and a gravel path leading to it.

A stone building with a patio area, string lights, and outdoor seating.

A cozy log cabin interior with a wooden staircase, a cushioned sofa, a small table, and a lamp.

18. Makanda Inn

Makanda

Ann

$249 nightly

$275 total

Oct 5 - Oct 6

Total with taxes and fees

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

19. Town House Inn

Jackson

Julie

$66 nightly

$71 total

Oct 25 - Oct 26

Total with taxes and fees

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

An outdoor patio with stone walls, wicker furniture, and large windows.

20. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Valarie

$106 nightly

$119 total

Oct 11 - Oct 12

Total with taxes and fees

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Pocahontas Hotel Reviews

Candlewood Suites Cape Girardeau by IHG

8/10 Good

"I usually stay here if I need to because I travel back and forth from northern IL and I usually have a lot of food to take home to southern MS. The full size fridge and freezer is very nice to have available and you don’t have to book a super fancy room to get one. Housekeeping can be hard work, but missing a rather large blood stain on the wall behind the door is disturbing. Thankfully I always travel with Lysol wipes and cleaned it up."

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"EVERYONE was EXTREMELY FRIENDLY even maintenance all FRIENDLY"

* On the Wine Trail * Hot Tub * Wi-Fi *

10/10 Excellent

"I really could not say a bad thing about this place. I felt comfortable and welcomed immediately when I walked in. They have a cabin log journal that everyone writes down the experiences they had and it was such a lovely touch to see how others had a great time, and to learn other spots to check out. Snack basket was a great perk too! If in the area again, I would choose the wine loft a thousand times."

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Clean rooms. Nice breakfast. Very nice staff."

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

10/10 Excellent

"My husband and I enjoyed our stay here very much. The cabin was cozy, relaxing and extremely clean. We loved sitting in the dock fishing and hanging out in the screened in porch. Tanya was very easy to reach and responded to our needs quickly. Looking for ward to coming back again!!"

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

Beautiful location in the secluded woods

8/10 Good

"It was good, except the A/C was in the living room and you need to keep the bedroom doors open to get the air."

Town House Inn Cape Giradreau

8/10 Good

"The outside needed cleaning, but the room was very clean and well maintained."

More cheap stays in Pocahontas

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

$59 nightly

$67 total

Nov 1 - Nov 2

Total with taxes and fees

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

$72 nightly

$81 total

Oct 11 - Oct 12

Total with taxes and fees

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

$85 nightly

$101 total

Oct 11 - Oct 12

Total with taxes and fees

8/10 Very Good! (1,001 reviews)

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

$89 nightly

$102 total

Oct 11 - Oct 12

Total with taxes and fees

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

$101 nightly

$115 total

Oct 11 - Oct 12

Total with taxes and fees

Hampton Inn Cape Girardeau I 55 East

207 S Mt Auburn Rd Cape Girardeau MO

$106 nightly

$119 total

Oct 11 - Oct 12

Total with taxes and fees

9.6/10 Exceptional! (849 reviews)

Hotels in Pocahontas with star-rating

Frequently asked questions

What is the best area to stay in Pocahontas?

The best area to stay in Pocahontas is near the historic downtown square, which offers convenient access to local amenities and attractions.This central area is the heart of Pocahontas, featuring well-preserved historic buildings and local businesses. You'll find a few local eateries and shops clustered around the Randolph County Courthouse, which is a prominent landmark. The general layout is walkable, making it easy to explore on foot.For couples or solo travelers looking for a relaxed experience, staying near the downtown square is ideal. It provides an opportunity to easily visit local museums, the public library, and enjoy the small-town atmosphere. The convenience of having dining options and points of interest within walking distance contributes to a stress-free stay.Travelers prioritizing access to outdoor activities will find accommodations on the outskirts of town convenient for reaching nearby natural areas like the Black River.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Pocahontas.

How much is the nightly rate at a Pocahontas hotel?

Prices for hotels in Pocahontas often vary, but you can find a great deal from $67 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Find hotels in Pocahontas, MO from $67

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Pocahontas

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Pocahontas hotels

1. Drury Plaza Hotel Cape Girardeau Conference Center

2. The Riverview

3. Drury Inn & Suites Jackson MO

4. Drury Inn & Suites Cape Girardeau

5. Candlewood Suites Cape Girardeau by IHG

6. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

7. Pear Tree Inn Cape Girardeau West

8. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

9. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

10. Home2 Suites by Hilton Carbondale

11. Courtyard by Marriott Cape Girardeau Downtown

12. Super 8 by Wyndham Carbondale

13. Fairfield Inn & Suites by Marriott Cape Girardeau

14. Holiday Inn Express & Suites Perryville by IHG

15. Tru By Hilton Cape Girardeau

16. Quality Inn Cape Girardeau North

17. Super 8 by Wyndham Perryville

18. Makanda Inn

19. Town House Inn

20. Hampton Inn Cape Girardeau I 55 East

Top Pocahontas Hotel Reviews

Candlewood Suites Cape Girardeau by IHG

Drury Inn & Suites Cape Girardeau

* On the Wine Trail * Hot Tub * Wi-Fi *

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Courtyard by Marriott Cape Girardeau Downtown

Beautiful location in the secluded woods

Town House Inn Cape Giradreau

More cheap stays in Pocahontas

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

Tru By Hilton Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hampton Inn Cape Girardeau I 55 East

Hotels in Pocahontas with star-rating

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app