Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Owensboro Resorts & Hotels with Spas

See all 68 Hotels in Owensboro
Comfort Inn & Suites

Comfort Inn & Suites

1355 N Plaza Dr, Rockport
3.0 out of 5.0
4.3 out of 5 (111 reviews)
Pleasant experience All good, nothing fancy bbbbbbbbbbbbbbbbbbbbbbvvvvvvvvvvvvvvvvg
  Sep 7, 2017

$83

$83
Comfort Suites

Comfort Suites

230 Salem Dr, Owensboro
3.0 out of 5.0
4.4 out of 5 (130 reviews)
We were town for a tournament & needed a place to stay. Room was clean. Pool & spa were clean as well. Great room for a good price. Will be using this hotel chain in the future.
  Nov 19, 2017

$84

$84
Courtyard by Marriott Owensboro

Courtyard by Marriott Owensboro

3120 Highland Pointe Dr, Owensboro
3.5 out of 5.0
4.6 out of 5 (227 reviews)
Nice hotelThe room was beautiful and very comfortable. Everything was clean and the bed was nice.
  Nov 24, 2017

$109

$109
Fairfield Inn by Marriott Owensboro

Fairfield Inn by Marriott Owensboro

800 Salem Dr, Owensboro
3.0 out of 5.0
4.0 out of 5 (162 reviews)
Central location, free breakfastThis is my 2nd stay and it was peaceful and convenient. I would definitely be back but next time I'll request a room on the 1st floor as the 2nd floor room I had this time had a really bad mildew odor. My room last time was perfect. I appreciate the firm mattress and clean bathroom. Staff was very ...
  Jul 4, 2017

$84

$84
Hampton Inn and Suites Owensboro/Downtown-Waterfront

Hampton Inn and Suites Owensboro/Downtown-Waterfront

401 West 2nd Street, Owensboro
3.0 out of 5.0
4.7 out of 5 (224 reviews)
Great view of the waterfrontSpent the weekend for our son's college scholarship competition. Room was wonderful, breakfast was yummy and the park was adorable. They had a special tree lighting ceremony and everyone was so welcoming. We will be back to stay at the Hampton in April as well as the rest of our trips to Owensboro ...
  Dec 4, 2017

$110

$110
Quality Inn Lewisport

Quality Inn Lewisport

9040 Us Highway 60 W, Lewisport
3.0 out of 5.0
3.4 out of 5 (39 reviews)
It'll Do...The hotel management was very polite and accommodating. Unfortunately, the rooms smelled very musty and were quite humid, even with the AC running. The breakfast was minimal, but gets the job done. We didn't get to eat in the breakfast area, as it only had 4 tables. It is about a 30 minute drive ...
  Jul 27, 2015

$90

$90
Sleep Inn

Sleep Inn

51 Bon Harbor Hls, Owensboro
3.0 out of 5.0
4.3 out of 5 (185 reviews)
Great hotel near the airportOur flight was delayed a day so we had to find a hotel in the snowstorm. We chose this one as I had a 5 year old that really wanted to swim. It was a great choice! Indoor pool & hot tub, free WiFi, free parking, free breakfast, comfortable room! Would highly recommend!
  Jan 15, 2018

$80

$80
Map

Recently booked Resorts & Hotels with Spas in Owensboro

Days Inn Owensboro
2.5 out of 5.0
Last booking: 6 hours ago
Holiday Inn Owensboro Dwtn - Ohio River
3.5 out of 5.0
Last booking: 7 hours ago
Hampton Inn and Suites Owensboro/Downtown-Waterfront
3.0 out of 5.0
Last booking: 8 hours ago
Super 8 Owensboro
2.5 out of 5.0
Last booking: 22 hours ago
Sleep Inn Henderson-Evansville South
3.0 out of 5.0
Last booking: 23 hours ago
Ramada Owensboro
2.5 out of 5.0
Last booking: 27 hours ago
Hampton Inn Owensboro South
3.0 out of 5.0
Last booking: 27 hours ago
Sleep Inn
3.0 out of 5.0
Last booking: 37 hours ago

Owensboro Resorts & Spa Travel Guide

Indulge Yourself with a Owensboro Spa Vacation

Pack up your luggage and forget your concerns to jumpstart your stress-free time-off. Searching for an extravagant spa hotel that nestles you in the lap of luxury? We got you covered. Would you prefer to rest in a soothing remote spa resort? No worries. In fact, this area is so popular that it saw a huge increase of visitors that are making it their perfect spot to unwind. If your ideal spa vacation is to get a rest from the daily grind for a little rest and relaxation, then you'll find more visitors are finding out that this city is the ideal retreat to do little and love every moment.

Book a Owensboro Spa Vacation that Won't Break the Bank

Finding your ideal hotel to relax in won't be an issue as Owensboro has plenty of great choices to choose from. Unwind and stretch out for a bit. After that you can book your first appointment to indulge yourself at a nearby spa. After you've indulged yourself by enjoying a massage, rejuvenating in the steam room, or soaking in the whirlpool, spend your evening getting relaxed as you enjoy the small-town atmosphere of this quaint city. Further, you can enjoy your time knowing it's easy to get around town or to grab a table at a popular restaurant. If you decide to take a walk around the area, you can spend a relaxed evening taking in this charming city's casual vibe. Regardless of where you wind up, just be sure to take it easy. Your spa trip shouldn't be anything but exceptionally relaxing.

Providing plenty of relaxing retreats and and tranquil locations, it's easily apparent why more and more people are choosing Owensboro as their stress-free spa vacation sanctuary.