A large suspension bridge, industrial cranes, and a calm river.

Panama Canal Zone Vacations from $938

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The Latest Panama Canal Zone Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 15 - Jan 18

    Megapolis Hotel Panamá + Flight

    San Francisco
    3 nights
    4.5 star property
    8.6/10 - Excellent (1,879 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,438
    $938
    per traveler
    found 1 day ago
    Megapolis Hotel Panamá
  • Feb 5 - Feb 11

    Casa Lefevre By Wynwood House + Flight

    Casco Viejo
    6 nights
    3.0 star property
    9.6/10 - Exceptional (16 reviews)
    Roundtrip • Trinidad (POS) - Panama City (PTY)
    POS - PTY • Nonstop PTY - POS • Nonstop
    Save 100% on your flight
    $2,169
    $1,296
    per traveler
    found 19 hours ago
    Casa Lefevre By Wynwood House
  • Jan 15 - Jan 18

    Casa Mallet by Wynwood House + Flight

    Casco Viejo
    3 nights
    3.5 star property
    9.8/10 - Exceptional (31 reviews)
    "I would highly recommend, the service I received was impeccable and just a wonderful experience! I was a bit hesitant regarding the location but once I got there, it turned out to be perfect. The concierge staff was such a pleasure to work with especially ‘Jerry’, who provided recommendations and information. This was such a blessing to us. I would stay here again in a heart beat. It’s a must stay!"
    Reviewed September 16, 2026
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $2,135
    $1,375
    per traveler
    found 1 day ago
    Casa Mallet by Wynwood House
  • Jan 19 - Jan 23

    Central Hotel Panama Casco Viejo + Flight

    Casco Viejo
    4 nights
    4.0 star property
    9.0/10 - Wonderful (1,004 reviews)
    "Excellent location. Breakfast buffet was good. Air conditioning excellent. Staff was excellent. Shower leaked badly. Mold on bathroom grout. Would stay there again."
    Reviewed November 12, 2026
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $2,133
    $1,432
    per traveler
    found 1 day ago
    Central Hotel Panama Casco Viejo
  • Feb 5 - Feb 11

    Casa Love by Wynwood House + Flight

    Casco Viejo
    6 nights
    3.0 star property
    8.6/10 - Excellent (32 reviews)
    "The unit we stayed in was large and fully equipped, with a balcony and a full kitchen. The building was secure and conveniently located within walking distance to everything in casco viejo. There are lots of shops and restaurants nearby and we felt mostly safe walking around. The only issue we had was that the code to our lockbox didn’t work when we arrived. However, we texted the property staff and they were able to give us another code that worked right away. The internet in the unit worked..."
    Reviewed August 19, 2026
    Roundtrip • Trinidad (POS) - Panama City (PTY)
    POS - PTY • Nonstop PTY - POS • Nonstop
    $1,434
    $996
    per traveler
    found 19 hours ago
    Casa Love by Wynwood House

Discover the most popular places to visit in Panama Canal Zone

Panama Canal Zone Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How do vacation package prices compare across popular destinations in the Panama Canal Zone?

For a week-long trip, Panama Canal Zone vacation package deals are typically a little cheaper in Panama City than in Colon, though both destinations offer a wide range of prices. Expect to pay around $1,000 per adult for a package in Panama City, and around $1,050 per adult in Colon.


*Package prices shown are the average total cost per adult across Expedia bookings over the past year and may change depending on availability, dates, and demand.

How can I save money on a Panama Canal Zone vacation package?

When you bundle, you can save up to 30%*. To save money on a Panama Canal Zone package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.

What's included in a Panama Canal Zone vacation package?

A Panama Canal Zone vacation package lets you combine flights, hotel stays, and rental cars, based in one of the region's top destinations like Panama City or Colon. In Panama City, most hotels offer airport shuttle service to and from Tocumen Intl. Airport (PTY) or Marcos A. Gelabert Intl. Airport (PAC), and most also include free breakfast. In Colon, most hotels provide airport shuttle service to and from Enrique Adolfo Jimenez Airport (ONX), and most also include free breakfast.


Exactly what's included will vary by hotel and package, so it's worth reviewing the details before you confirm your booking.

Which destinations in the Panama Canal Zone offer the best-value vacation package deals?

Colon and Panama City are some of the top destinations for cheap Panama Canal Zone vacation package deals. For an affordable weekend getaway, Colon is often among the most budget-friendly options, with package prices starting around $400 per adult. For notable bundle savings, Panama City is often among the best options, with flight-and-hotel bundles saving around $105 per adult for week-long trips.


Browse cheap vacation packages in the Panama Canal Zone on Expedia to compare current deals.


*Package prices shown are the average total cost per adult across Expedia bookings over the past year and may change depending on availability, dates, and demand.

When is the best time to visit the top destinations in the Panama Canal Zone?

The best time for a Panama Canal Zone vacation package depends on which destination you choose.


Panama City sees its highest demand in December and July, when average temperatures are around 79°F with highs around 85°F. If you prefer fewer crowds, October, January, and May are quieter months, with May seeing average temperatures around 80°F and highs around 86°F.


Colon is busiest in May and July, with average temperatures around 80°F and highs around 83-84°F. For a quieter visit, from January to February is less crowded, with average temperatures around 79°F and highs around 83°F.

What package types are available across the top destinations in the Panama Canal Zone?

The Panama Canal Zone offers a variety of vacation package types across its popular destinations like Panama City and Colon:

  • Budget: In Panama City, Hostal Familiar Carmencita - Hostel, rated 8.8 out of 10 by travelers, provides free WiFi and air conditioning for a comfortable stay.
  • Couples: Megapolis Hotel Panamá in Panama City, rated 8.5 out of 10 by travelers, features an outdoor pool and a hot tub, making it a relaxing choice for two.
  • Family: In Colon, the 3.5-star Gamboa Rainforest Reserve, rated 8.3 out of 10 by travelers, offers family rooms and a playground, set amidst a beautiful location.
  • Breakfast: Hotel Ojos del Rio in Panama City, a 3.5-star property rated 7.6 out of 10 by travelers, includes free breakfast and a restaurant.
  • Pet-friendly: Cabañas Colindas in Panama City, rated 8.3 out of 10 by travelers, welcomes pets and offers family rooms and free breakfast.

Which destinations should I consider for a Panama Canal Zone vacation?

For your Panama Canal Zone vacation, consider these destinations based on your travel style:

  • Panama City: This is a popular package base with extensive lodging options, ideal for families and travelers seeking city and urban attractions, entertainment, and business amenities.
  • Colon: A smaller package base, Colon is well-suited for those interested in the Canal's operations, outdoor activities, and city attractions.
  • Ancon: For travelers prioritizing proximity to the iconic Miraflores Locks and other Canal-related sights, Ancon offers a good lodging base with family-friendly attractions.

Is Panama Canal Zone better suited for a beach vacation or a cultural trip?

A Panama Canal Zone vacation package offers a rich blend of cultural and urban experiences, making it well-suited for travelers interested in history, engineering, and city life, and also provides opportunities for coastal relaxation.


Cities like Panama City and Colon are central urban hubs with numerous attractions. In Panama City, you can explore historic sites like Panama Viejo or enjoy the waterfront along Amador Causeway. Colon offers insights into the Canal's operations at the Canal Expansion Observation Center. The iconic Miraflores Locks in Ancon are a must-see for understanding the Canal's engineering marvel.


For those seeking some sun and sand, Panama City has Veracruz Beach, and areas near Colon feature beaches like Coronado Beach.

Which airports serve the main destinations in the Panama Canal Zone?

For a Panama Canal Zone vacation, several airports provide convenient access to the region's main destinations. Panama City is served by Panama City (PTY-Tocumen Intl.) and Panama City (PAC-Marcos A. Gelabert Intl.). For travelers heading to Colon, Colon (ONX-Enrique Adolfo Jimenez) is the primary airport.

What are the top things to do across the destinations in the Panama Canal Zone?

The Panama Canal Zone offers a variety of attractions across its constituent cities, making a Panama Canal Zone vacation rich in experiences:


Browse and book things to do in the Panama Canal Zone on Expedia.

Which destinations in the Panama Canal Zone have all-inclusive resorts?

Panama City is the primary destination in the Panama Canal Zone with all-inclusive resorts, which you can book as part of a Panama Canal Zone vacation package:


Browse all-inclusive resorts in the Panama Canal Zone on Expedia.

Are there family vacation packages in the Panama Canal Zone with kid-friendly amenities?

Yes, family vacation packages in the Panama Canal Zone can include hotels with kid-friendly amenities across destinations like Panama City and Colon:

  • La Concordia Boutique Hotel: In Panama City, this 4-star property, rated 9.3 out of 10 by travelers, offers family rooms and a kitchen, with travelers frequently praising its great location and spacious rooms.
  • Gamboa Rainforest Reserve: In Colon, the 3.5-star Gamboa Rainforest Reserve, rated 8.3 out of 10 by travelers, features family rooms and a playground, and travelers often highlight the spacious rooms and helpful staff.
  • Waldorf Astoria Panama: This 5-star hotel in Panama City, rated 8.6 out of 10 by travelers, provides family rooms and an outdoor pool, with travelers frequently praising the friendly and helpful staff and spacious rooms.
  • Marina Hotel at Shelter Bay: Located in Colon, this hotel, rated 7.9 out of 10 by travelers, includes family rooms and a hot tub, and travelers note the amazing facilities and great food.

What luxury vacation packages are available in the Panama Canal Zone?

Luxury Panama Canal Zone vacation packages are primarily available in Panama City, offering high-end stays:


Browse luxury vacation packages in the Panama Canal Zone on Expedia to compare options.

When should I book vacation packages for the top destinations in the Panama Canal Zone?

For cheap Panama Canal Zone vacation package deals, booking around 1 to 9 weeks ahead is a useful window, though the timing varies slightly across its main destinations.


Travelers tend to book trips to these destinations most often in March, May, from July to August, and in December. If you're planning a spontaneous getaway, Expedia also offers last-minute Panama Canal Zone vacation packages.

How many days do you need for a Panama Canal Zone vacation?

Most Panama Canal Zone vacation packages last around 5 days, but the ideal trip length depends on where you're going and what you'd like to experience.


Panama City, a vibrant urban center known for its city attractions, is often enjoyed with a trip of around 5 days. While some travelers opt for weekend trips, most choose week-long stays to explore sights like the Miraflores Locks.


Colon, a city known for its urban attractions and outdoor activities, also sees typical trips of around 5 days. Many travelers choose week-long stays here, with some opting for weekend trips to visit places like the Colon Free Zone.

Can I change or cancel my Panama Canal Zone vacation package if my plans change?

Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.

Do One Key members get extra savings when booking Panama Canal Zone vacation packages?

Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.

Does Expedia offer Book Now, Pay Later Panama Canal Zone vacation packages?

Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Panama Canal Zone vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.

How do I find last-minute vacation packages to Panama Canal Zone?

To find last-minute vacation packages to Panama Canal Zone, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.

How does free cancellation work on Panama Canal Zone vacation packages?

Free cancellation on a Panama Canal Zone vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.

Is it cheaper to book a Panama Canal Zone vacation as a package or separately?

An Expedia vacation package could land you great savings when compared to arranging flights and hotels separately. Better still, you can tailor your Panama Canal Zone getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.

Why should I book my Panama Canal Zone vacation package with Expedia?

Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.