Hilton Rochester Mayo Clinic Area

Property class: 3.5

Choose dates to view prices

A short walk from Mayo Clinic, Hilton Rochester Mayo Clinic Area provides a terrace, a hair salon, and dry cleaning/laundry services. Treat yourself to a massage, aromatherapy, or a body wrap at Healing Touch, the onsite spa. Be sure to enjoy a meal at the two on-site restaurants. In addition to a fireplace in the lobby and a bar, guests can connect to free in-room WiFi.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Spa
  • Free WiFi
  • Air conditioning

Room options

Available filters for rooms
Showing 30 of 30 rooms

View all photos for Room, 1 King Bed with Sofa bed, Bathtub

A hotel room with a large bed, a desk with a chair, a TV, and a view of the cityscape through the windows.

Room, 1 King Bed with Sofa bed, Bathtub

9.6 out of 10
Exceptional
(42 reviews)
  • City view
  • 384 sq ft
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Room, 1 King Bed, Mobility Accessible, Bathtub (Roll-In Shower)

A hotel room with a bed, a desk, a chair, a TV, and a window with a city view.

Room, 1 King Bed, Mobility Accessible, Bathtub (Roll-In Shower)

10.0 out of 10
Exceptional
(2 reviews)
  • 384 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Hearing Accessible, Bathtub (Hearing)

A hotel room with a large bed, a desk with a chair, a TV, and a view of the cityscape through the windows.

Room, 1 King Bed, Hearing Accessible, Bathtub (Hearing)

8.8 out of 10
Excellent
(5 reviews)
  • 384 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Suite, 1 King Bed, Bathtub, Corner

A modern hotel room with a large window, a sofa set, a dining table, and a lamp.

Luxury Suite, 1 King Bed, Bathtub, Corner

  • 1202 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Suite, 1 King Bed with Sofa bed, Hearing Accessible, Bathtub (Hearing)

A modern hotel room with a large window, a sofa set, a dining table, and a lamp.

Suite, 1 King Bed with Sofa bed, Hearing Accessible, Bathtub (Hearing)

  • 615 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Executive Room, 1 King Bed with Sofa bed, Bathtub

A hotel room with a large bed, a desk with a chair, a TV, and a view of the cityscape through the windows.

Executive Room, 1 King Bed with Sofa bed, Bathtub

  • 384 sq ft
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Executive Room, 1 King Bed, Mobility Accessible, Bathtub (Roll-In Shower, Mobility)

A hotel room with a bed, a desk, a chair, a TV, and a window with a city view.

Executive Room, 1 King Bed, Mobility Accessible, Bathtub (Roll-In Shower, Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • 384 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Executive Suite, 1 King Bed with Sofa bed, Mobility Accessible, Bathtub (Roll-In Shower, Concierge)

A hotel room with a large bed, a desk with a chair, a TV, and a view of the cityscape through the windows.

Executive Suite, 1 King Bed with Sofa bed, Mobility Accessible, Bathtub (Roll-In Shower, Concierge)

  • 615 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Executive Suite, 1 King Bed, Bathtub (Concierge)

A hotel room with a large bed, a desk with a chair, a TV, and a view of the cityscape through the windows.

Executive Suite, 1 King Bed, Bathtub (Concierge)

  • 615 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Presidential Suite, Multiple Beds, Hearing Accessible, Bathtub (Hearing)

A hotel room with a large bed, a desk with a chair, a television, and a view of a cityscape through a large window.

Presidential Suite, Multiple Beds, Hearing Accessible, Bathtub (Hearing)

  • 1698 sq ft
  • Sleeps 5
  • 2 King Beds and 1 Double Sofa Bed

View all photos for Room, 2 Queen Beds, Bathtub

A hotel room with two beds, a desk, a chair, and a view of the outdoors.

Room, 2 Queen Beds, Bathtub

9.4 out of 10
Exceptional
(18 reviews)
  • 384 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Mobility Accessible, Bathtub (Mobility)

A hotel room with two beds, a desk, a chair, and a view of the outdoors.

Room, 2 Queen Beds, Mobility Accessible, Bathtub (Mobility)

8.0 out of 10
Very good
(4 reviews)
  • 384 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Hearing Accessible, Bathtub (Hearing)

A hotel room with two beds, a desk, a chair, and a view of the outdoors.

Room, 2 Queen Beds, Hearing Accessible, Bathtub (Hearing)

  • 384 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Executive Room, 2 Queen Beds, Bathtub

A hotel room with two beds, a desk, a chair, and a view of the outdoors.

Executive Room, 2 Queen Beds, Bathtub

9.8 out of 10
Exceptional
(9 reviews)
  • 384 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Executive Room, 2 Queen Beds, Mobility Accessible, Bathtub (Mobility)

A hotel room with two beds, a desk, a chair, and a view of the outdoors.

Executive Room, 2 Queen Beds, Mobility Accessible, Bathtub (Mobility)

  • 384 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Executive Suite, 2 Queen Beds, Mobility Accessible, Bathtub (Mobility)

A hotel room with a sofa, armchair, and a coffee table.

Executive Suite, 2 Queen Beds, Mobility Accessible, Bathtub (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • 849 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds

View all photos for Executive Suite, 2 Queen Beds, Bathtub

A hotel room with a sofa, armchair, and a coffee table.

Executive Suite, 2 Queen Beds, Bathtub

  • 849 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Presidential Suite, Multiple Beds, Bathtub

A hotel room with a large bed, a desk with a chair, a television, and a view of a cityscape through a large window.

Presidential Suite, Multiple Beds, Bathtub

  • 1000 sq ft
  • Sleeps 5
  • 2 King Beds and 1 Double Sofa Bed

View all photos for Executive Room, 1 King Bed with Sofa bed, Mobility Accessible, Bathtub

A hotel room with a large bed, a desk, a chair, a small table, and a TV.

Executive Room, 1 King Bed with Sofa bed, Mobility Accessible, Bathtub

  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Room, 1 King Bed, Mobility Accessible, Bathtub (Mobility, Roll-In Shower)

A hotel room with a large bed, a desk, a chair, a small table, and a TV.

Room, 1 King Bed, Mobility Accessible, Bathtub (Mobility, Roll-In Shower)

  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed with Sofa bed, Bathtub, Corner

A hotel room with a large bed, a sofa, a desk with a TV, and a view of the city.

Room, 1 King Bed with Sofa bed, Bathtub, Corner

10.0 out of 10
Exceptional
(6 reviews)
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Executive Room, 1 King Bed with Sofa bed, Bathtub, Corner

A hotel room with a large bed, a sofa, a desk with a TV, and a view of the city.

Executive Room, 1 King Bed with Sofa bed, Bathtub, Corner

9.0 out of 10
Wonderful
(2 reviews)
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Room, 1 King Bed with Sofa bed, Hearing Accessible, Bathtub (Hearing)

A hotel room with a large bed, a sofa, a desk with a TV, and a view of the city.

Room, 1 King Bed with Sofa bed, Hearing Accessible, Bathtub (Hearing)

9.4 out of 10
Exceptional
(3 reviews)
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 King Bed, Mobility Accessible, Bathtub (2 Rooms, Roll-In Shower)

A hotel room with a large bed, a desk with a chair, a TV, and a view of the cityscape through the windows.

Suite, 1 King Bed, Mobility Accessible, Bathtub (2 Rooms, Roll-In Shower)

  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Suite, 1 King Bed, Bathtub (2 Rooms)

A hotel room with a large bed, a desk with a chair, a TV, and a view of the cityscape through the windows.

Suite, 1 King Bed, Bathtub (2 Rooms)

9.0 out of 10
Wonderful
(2 reviews)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Suite, 1 King Bed, Hearing Accessible, Bathtub (2 Rooms, Hearing)

A hotel room with a large bed, a desk with a chair, a TV, and a view of the cityscape through the windows.

Suite, 1 King Bed, Hearing Accessible, Bathtub (2 Rooms, Hearing)

  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Suite, 2 Queen Beds, Hearing Accessible, Bathtub (2 Rooms, Hearing)

A hotel room with a sofa, armchair, and a coffee table.

Suite, 2 Queen Beds, Hearing Accessible, Bathtub (2 Rooms, Hearing)

  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds, Mobility Accessible, Bathtub (2 Rooms)

A hotel room with a sofa, armchair, and a coffee table.

Suite, 2 Queen Beds, Mobility Accessible, Bathtub (2 Rooms)

  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds, Bathtub (2 Rooms)

A hotel room with a sofa, armchair, and a coffee table.

Suite, 2 Queen Beds, Bathtub (2 Rooms)

  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Luxury Suite, 1 King Bed, Bathtub (2 Room)

A hotel room with a large bed, a desk with a chair, a television, and a window with a city view.

Luxury Suite, 1 King Bed, Bathtub (2 Room)

  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

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About the neighborhood

Located in Downtown Rochester neighborhood, Hilton Rochester Mayo Clinic Area is connected to the convention center. Soldiers Field Veterans Memorial and Assisi Heights are local landmarks, and the area's natural beauty can be seen at Quarry Hill Nature Center and Mayo Park. Looking to enjoy an event or a game while in town? See what's happening at Mayo Civic Center or Rochester Recreation Center. Visit our Rochester travel guide
Map
10 East Center Street, Rochester, MN, 55904

What's nearby

  • Shops University Square
    1 min walk - 0.1 miles
  • University of Minnesota-Rochester
    2 min walk - 0.1 miles
  • Mayo Civic Center
    3 min walk - 0.2 miles
  • Rochester Civic Theater
    3 min walk - 0.2 miles
  • Rochester Art Center
    7 min walk - 0.4 miles

Getting around

  • Rochester, MN (RST-Rochester Intl.)
    17 min drive

Restaurants

  • Hollandberry Pannekoeken
    3 min walk
  • Lumi Restaurant
    6 min walk
  • Mill Valley Kitchen
    2 min walk
  • Victoria's Ristorante & Wine Bar
    2 min walk
  • Chester's Kitchen & Bar
    3 min walk

About this property

Hilton Rochester Mayo Clinic Area

  • Hotel near Mayo Civic Center
  • A short walk from Mayo Clinic, Hilton Rochester Mayo Clinic Area provides a terrace, a hair salon, and dry cleaning/laundry services. Indulge in a massage, aromatherapy, and a body wrap at Healing Touch, the onsite spa. Be sure to enjoy a meal at the two on-site restaurants. Free in-room WiFi is available to all guests, along with a fireplace in the lobby and a bar.
  • Additional perks include:
    • An indoor pool along with sun loungers
    • Cooked-to-order breakfast (surcharge), valet parking (surcharge), and a TV in the lobby
    • A front-desk safe, a ballroom, and smoke-free premises
    • A banquet hall, wedding services, and a vending machine
    • Guest reviews give top marks for the helpful staff
  • Room features
  • All 264 rooms boast comforts such as laptop-compatible safes and laptop-friendly workspaces, in addition to perks like air conditioning and bathrobes.
  • Extra amenities include:
    • Hypo-allergenic bedding and free cribs/infant beds
    • Tubs or showers, free toiletries, and hair dryers
    • 55-inch LCD TVs with satellite channels
    • Refrigerators, microwaves, and coffee/tea makers

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Frequently asked questions

Does Hilton Rochester Mayo Clinic Area have a pool?

Yes, this property has an indoor pool. Pool access is from 5:00 AM–10:00 PM.

How much does it cost to stay at Hilton Rochester Mayo Clinic Area?

As of Oct 24, 2026, prices found for a 1-night stay for 2 adults at Hilton Rochester Mayo Clinic Area on Nov 7, 2026 start from $205, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Hilton Rochester Mayo Clinic Area pet-friendly?

No, only service animals are welcome at the property.

How much is parking?

Valet parking is available for USD 35 per night.

What time is check-in at Hilton Rochester Mayo Clinic Area?

Check-in start time: 3:00 PM; Check-in end time: midnight. Late check-in is available during limited hours.

What time is check-out at Hilton Rochester Mayo Clinic Area?

Check-out is at noon.

Where is Hilton Rochester Mayo Clinic Area located?

Located in Downtown Rochester, this spa hotel is within a 5-minute walk of Shops University Square and Mayo Civic Center. Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus are also within 1 mi (2 km).

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Hilton Rochester Mayo Clinic Area Reviews

9.6

Exceptional

9.8

Cleanliness

10

Location

9.6

Staff & service

9.8

Property conditions & facilities
Rating 10 - Excellent. 539 out of 654 reviews
Rating 8 - Good. 72 out of 654 reviews
Rating 6 - Okay. 24 out of 654 reviews
Rating 4 - Poor. 9 out of 654 reviews
Rating 2 - Terrible. 10 out of 654 reviews

Reviews

Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean rooms, great staff, convenient location.
Stayed 1 night in Oct 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location
Stayed 1 night in Oct 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The porters were particularly observant, kind, and helpful. Really made the stay effortless and comfortable.
Stayed 2 nights in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Super nice and helpful staff from the moment we arrived. If there for Mayo clinic they provide rides to appointments ( and for people not there for Mayo too) rooms were very clean and comfortable pool and hot tub were awesome close to restaurants and shops. will stay again
Stayed 4 nights in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely stay very helpful staff and enjoyed happy hour specials
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was as amazing as my room. Clean spacious and perfect location.
Stayed 4 nights in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Convenient, short walk to Mayo and two excellent restaurants.
Stayed 2 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Helpful staf,restaurants are close by
Stayed 3 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean with lots of amenities. Very friendly and helpful staff.
Stayed 2 nights in Jun 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good location in downtown Rochester. Lots of good eateries nearby. Art walk tour is interesting.
Stayed 2 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff goes above and beyond to make your stay the best!
Stayed 5 nights in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, property conditions & facilities
Very clean and great restaurant as well.
Stayed 2 nights in Feb 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel was beautiful and spotless! Staff was friendly. Even the option to order Benedicts directly to your room! Will definitely choose to stay here again!
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room was lovely!
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great view. Clean room. Comfortable bed. Refrigerator was very small.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Had a great stay. Room was very clean and staff was very courteous.
Stayed 1 night in Nov 2025
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
The room was spotless and comfortable.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Clean room, amazing staff. We enjoyed our stay!
Stayed 5 nights in Nov 2025
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Pleasant, short walk to Mayo. Excellent and reasonably priced restaurants within the hotel. My go to option for treatment visits.
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Great hotel and location. Will definitely select this property again for my next stay in Rochester.
Stayed 2 nights in Oct 2025
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Very courteous staff, loved the valet guy!
Stayed 1 night in Dec 2025
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It met my expectations. The car service to Mayo appointments is a plus.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Comfortable quiet and clean
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Clean and Confortable room, good and attention service
Stayed 1 night in Dec 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
My stay at the Hilton Mayo Clinic is consistently exceptional. It is the only hotel I rebook and will continue to do so. The room, staff, attention to detail, and overall experience is superb. The access and ease to the Clinic makes the visit stress free. I highly recommend this hotel particularly if you are a frequent patient at the Clinic. This hotel is worth the price. Top rating.
Stayed 3 nights in Mar 2026