A short walk from Mayo Clinic, Residence Inn by Marriott Rochester Mayo Clinic Area provides free full breakfast, a free grocery shopping service, and a free manager's reception. Free in-room WiFi is available to all guests, along with a rooftop terrace and shopping on site.
Located in Downtown Rochester, a neighborhood in Rochester, Residence Inn by Marriott Rochester Mayo Clinic Area is in the entertainment district. Rochester Civic Theater and History Center of Olmsted County are cultural highlights, and some of the area's activities can be experienced at Soldiers Field Golf Course and Kutzky Park Tennis Center. Looking to enjoy an event or a game while in town? See what's happening at Mayo Civic Center or Rochester Recreation Center. Break out the clubs and hit the links with a golf course nearby, or seek out an adventure with hiking/biking trails. Visit our Rochester travel guide
441 W Center St Nw, Rochester, MN, 55901
What's nearby
American Cancer Society Hope Lodge
3 min walk - 0.2 miles
Shops University Square
5 min walk - 0.3 miles
University of Minnesota-Rochester
7 min walk - 0.4 miles
Mayo Civic Center
8 min walk - 0.5 miles
Rochester Civic Theater
8 min walk - 0.5 miles
Getting around
Minneapolis - St. Paul Intl. Airport (MSP)
83 min drive
Restaurants
Caribou Coffee
2 min walk
Victoria's Ristorante & Wine Bar
5 min walk
Spyhouse Coffee Roasters
4 min walk
Chester's Kitchen & Bar
6 min walk
Patient Cafeteria - Subway Level
5 min walk
About this property
Residence Inn by Marriott Rochester Mayo Clinic Area
Hotel remodeled in 2025 and located near Mayo Civic Center
A short walk from Mayo Clinic, Residence Inn by Marriott Rochester Mayo Clinic Area provides free full breakfast, a free grocery shopping service, and a free manager's reception. Stay connected with free in-room WiFi, and guests can find other amenities such as a rooftop terrace and shopping on site.
You'll also find perks like:
Limo/town car service, self parking (surcharge), and express check-out
1 meeting room, smoke-free premises, and multilingual staff
Barbecue grills, a TV in the lobby, and a banquet hall
Guest reviews give top marks for the helpful staff
Room features
All 89 rooms have comforts such as premium bedding and air conditioning, as well as perks like separate sitting areas and separate dining areas.
Extra conveniences in all rooms include:
Free infant beds and free extra beds
Bathrooms with shower/tub combinations and free toiletries
Separate sitting areas, separate dining areas, and recycling
Is Residence Inn by Marriott Rochester Mayo Clinic Area pet-friendly?
Yes, this property allows cats and dogs (limit 2 total). There's a fee of USD 150 per accommodation, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.
How much does it cost to stay at Residence Inn by Marriott Rochester Mayo Clinic Area?
As of Oct 23, 2026, prices found for a 1-night stay for 2 adults at Residence Inn by Marriott Rochester Mayo Clinic Area on Nov 13, 2026 start from $183, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking?
Self parking is available for USD 20 per day. Limited spots are available.
What time is check-in at Residence Inn by Marriott Rochester Mayo Clinic Area?
Check-in start time: 4:00 PM; Check-in end time: midnight. Late check-in is available during limited hours.
What time is check-out at Residence Inn by Marriott Rochester Mayo Clinic Area?
Check-out is at noon. Late check-out is available for a fee (subject to availability).
Where is Residence Inn by Marriott Rochester Mayo Clinic Area located?
Located in Downtown Rochester, this hotel is within a 5-minute walk of American Cancer Society Hope Lodge and Mayo Clinic. Mayo Civic Center and Mayo Clinic Hospital - Saint Marys Campus are also within 1 mi (2 km).
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Residence Inn by Marriott Rochester Mayo Clinic Area Reviews
8.6
Excellent
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
We were there for 3 nights while visiting Doctors at Mayo. The location is very good and is connected to the Mayo Subway. The hotel was clean and staff friendly.
Mayo Clinic in Rochester Minnesota is impressive. We were able to walk from our hotel through a pedestrian tunnel system to get to the hospital with access to other clinic buildings, restaurants and shopping. Very convenient for patients and families during the harsh Minnesota winters.I’m
The property was a little dated however the room was well appointed and neat. Awesome water pressure. Breakfast was good.
Stayed 5 nights in Oct 2024
Verified review
8/10 Good
David
Mar 12, 2024
Liked: Cleanliness, staff & service
Conveniently located to Mayo Clinic
We've stayed here numerous times over the last 3 years. I was glad to see that renovations are going to take place, as the rooms are starting to show wear/tear. The sofa was horribly uncomfortable, but the bed was decent. The convenience to the Mayo Clinic is unbeatable, so we will continue to stay here on future trips.
Stayed 2 nights in Mar 2024
Verified review
10/10 Excellent
Gregory
Dec 22, 2025
Liked: Cleanliness, staff & service, amenities
Really outstanding. Friendly and accommodating staff allowed me to check in early (post-surgery). So, that was a relief. Check-in otherwise was really quick and efficient. Treated me like a guest. Room was spotless and well furnished, good internet and video/TV service, large screen TV, very comfortable bed, breakfast had great variety and quality ingredients with pleasant breakfast room, and spotless bath and vanity. Everything was perfect. Direct access to Mayo Clinic Subway level was a great help.
Stayed 2 nights in Dec 2025
Verified review
10/10 Excellent
Laura
Sep 2, 2024
Liked: Cleanliness, staff & service
Disliked: Property conditions & facilities
I've never been to a more friendly and welcoming hotel. The staff was extremely helpful when there was a room mix up. They were exceptionally kind and accommodating. The hotel needs some updates, chairs were worn, furniture was in need of repair and the water took some time to get hot but i cannot speak highly enough of the wonderful staff.
Despite being under renovation, the room and common areas are clean and well maintained. Very light and pleasant breakfast room and lobby area. Excellent breakfast choices. One huge bonus is the direct connection to the Mayo Clinic via the pedestrian subway, connecting beyond to the Rochester skyway systems. This is a godsend in the winter when temperatures frequently plunge to single digits. I would definitely come back here if using the Mayo facilities. Great find.
Stayed 8 nights in Feb 2025
Verified review
4/10 Poor
Verified traveler
Apr 24, 2024
Liked: Cleanliness, staff & service, room comfort
Disliked: Property conditions & facilities
Our room was next to the elevators, so we had to listen to them rumble at all hours. The furniture was worn and shabby, and we could find no USB ports to charge our devices until the last day when we found some hiding in the alarm clock. The bed was comfortable. The complimentary breakfast was in general mediocre, although the egg dishes were both excellent.
Stayed 2 nights in Apr 2024
Verified review
8/10 Good
Verified traveler
Oct 1, 2023
Liked: Cleanliness, staff & service, room comfort
Close to Mayo Clinic
The facility is getting aged and room had an odor to it. Informed front desk of odor and they said it would be addressed, but they also noted that a facility update is planned for the near future.
The kitchen was a nice amenity for our stay. Breakfast was great and staff was super friendly and helpful. The subway connection to the Mayo Clinic is awesome and convenient.
Everything was very clean and all the staff was very nice, the only bummer is they are building a parking garage behind the hotel that blocks the view from the patio area but they still advertise with a view that doesn’t exist anymore