San Diego Vacations from $538

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Your San Diego Vacation

Reserve a San Diego vacation package and prepare to experience the best of this city. Consider staying in the neighborhood of Cartagena Centro, which is great for dining, shopping and cafes. Fill your days with tours of San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium, some of the attractions you just have to see during a trip to San Diego. Stop dreaming and start traveling. Browse the range of options on Expedia today and put your San Diego vacation plans into motion!

The Latest San Diego Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Osh Hotel Cartagena
Casa Fernandez by Soho
Hotel Isla del Encanto
Casa Catalina de Mokana By SoHo
Hotel Casona del Colegio

Where to stay in San Diego

Find the best San Diego areas and neighborhoods for the activities you enjoy most. Learn more about San Diego

San Diego Hotel Deals

Sofitel Legend Santa Clara Cartagena

Sofitel Legend Santa Clara Cartagena

5 out of 5
Calle Del Torno, 39 - 29 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$506 nightly
The price is $506 total per night from Jan 6 to Jan 7
$506 total
Jan 6 - Jan 7
9.4/10 Exceptional! (1,005 reviews)
Nous avons séjourné deux nuits au Sofitel Legend et avons été agréablement surpris par la qualité de l’établissement. Jusqu’à ce séjour, nous n’avions jamais été pleinement satisfaits dans les hôtels Sofitel. Nous occupions une suite junior dans l’aile coloniale (historique). Compte tenu des contraintes ...

Reviewed on Dec 25, 2025

Sofitel Legend Santa Clara Cartagena
Bastión Luxury Hotel

Bastión Luxury Hotel

4.5 out of 5
Calle del Sargento No. 6-87 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$282 nightly
The price is $282 total per night from Jan 22 to Jan 23
$282 total
Jan 22 - Jan 23
9.4/10 Exceptional! (1,007 reviews)
A place to go back, everything was perfect

Reviewed on Jan 3, 2026

Bastión Luxury Hotel
Nacar Hotel Cartagena, Curio Collection by Hilton

Nacar Hotel Cartagena, Curio Collection by Hilton

4 out of 5
Calle del Curato No. 38 - 99 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$216 nightly
The price is $216 total per night from Jan 24 to Jan 25
$216 total
Jan 24 - Jan 25
9/10 Wonderful! (474 reviews)
Courteous staff and beautiful facilities in a beautiful location

Reviewed on Dec 29, 2025

Nacar Hotel Cartagena, Curio Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.