San Luis Vacations from $1,080

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The Latest San Luis vacation packages

Price found within the past 48 hours. Click for updated prices.
23 Living

23 Living

El Poblado
Save 100% on your flight
$1,080
per person
Dec 8 - Dec 15
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Medellín (MDE)
9.6/10 Exceptional! (79 reviews)
Excelente ubicación, el personal muy amable y servicial, la habitación súper comoda, equipada y bonita. Lo recomiendo 100%

Reviewed on Oct 20, 2026

Casa Linda Guatapé

Casa Linda Guatapé

$1,292
per person
Dec 30 - Jan 4
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Medellín (MDE)
7.8/10 Good! (19 reviews)
Revellion by EP

Revellion by EP

El Poblado
Save 100% on your flight
$1,852
per person
Dec 27 - Jan 2
found 1 day ago
Roundtrip flight included
Miami (MIA) to Medellín (MDE)
9/10 Wonderful! (7 reviews)
In the heart of all parque Lleras and provenza!

Reviewed on Sep 8, 2026

Atma Villas Hotel Boutique Guatapé

Atma Villas Hotel Boutique Guatapé

$1,604
per person
Dec 30 - Jan 4
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Medellín (MDE)
8.8/10 Excellent! (47 reviews)
Joe's Place

Joe's Place

$103,206
per person
Dec 16 - Dec 22
found 1 day ago
Roundtrip non-stop flight included
San Juan (SJU) to Medellín (MDE)
No reviews
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Stay near popular San Luis attractions

El Balseadero Nature Park

You can take time to visit El Balseadero Nature Park during your travels to San Luis.
See properties

La Planta Waterfall

Commune with nature and explore the great outdoors at La Planta Waterfall during your travels in San Luis.
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What to do in San Luis

Hacienda Naples + Colombian Santorini

Hacienda Naples + Colombian Santorini

$140
per adult
Hacienda Naples + Colombian Santorini
Visit Hacienda Naples Theme Park by Pablo Escobar

Visit Hacienda Naples Theme Park by Pablo Escobar

$118
per adult
Visit Hacienda Naples Theme Park by Pablo Escobar
Scenic River Rafting, Swimming & Waterfall Hike

Private Family rafting adventure tour from Medellín

$280
per adult
Private Family rafting adventure tour from Medellín
See all activities in San Luis

San Luis Hotel Deals

Glamping Río Claro

Glamping Río Claro

Autopista Medellín-Bogotá San Luis Antioquia
Fully refundableReserve now, pay when you stay
$54 nightly
$54 total
Oct 26 - Oct 27
10/10 Exceptional! (1 review)
"Todo fue genial! 100% recomendado"

Reviewed on Apr 10, 2026

Glamping Río Claro
The Brown, Guatape, Autograph Collection

The Brown, Guatape, Autograph Collection

El Peñol - Guatape Paraje Guatapé Antioquia
Fully refundableReserve now, pay when you stay
$271 nightly
$271 total
Oct 28 - Oct 29
9.2/10 Wonderful! (567 reviews)
"Wow. Top 5 hotels I’ve ever stayed at! Would recommend anyone who comes to guatape to at least stay here one night"

Reviewed on Oct 23, 2026

The Brown, Guatape, Autograph Collection
Hotel Los Recuerdos

Hotel Los Recuerdos

Via Peñol Gatapé Km 19 Guatapé Antioquia
Fully refundableReserve now, pay when you stay
$98 nightly
$98 total
Oct 26 - Oct 27
Hotel Los Recuerdos
See all 642 properties in San Luis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best San Luis Vacation Packages

San Luis Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Jose Maria Cordova Intl. Airport (MDE)

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Frequently asked questions

How much does a San Luis vacation package cost?
You can pick up a vacation package to this top destination from $1,080 on Expedia. But how much your vacation to San Luis costs will depend on factors like the length of stay, hotel choice and season.
What are the cheapest months to go to San Luis?
You're likely to find lower rates and greater availability in November, December and January. Explore our cheap San Luis vacation packages and you could get some great off-season deals.
How many days is enough for San Luis?
Typically, a handful of days is enough to go to the major attractions during your San Luis vacation. But if you want to have some time to rest or take day tours, think about extending your itinerary.
How to find the best San Luis package deals?
Finding a cheap San Luis package deal is a cinch with Expedia. Once you've entered your destination and travel dates under our "Packages" tab, set your maximum budget, apply some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most affordable San Luis package deals. Want a simple trick to score the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book a San Luis vacation as a package?
An Expedia vacation package could land you great savings when compared to booking flights and stays individually. Better still, you can personalize your San Luis trip to match your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to San Luis?
If you're planning an impromptu San Luis vacation, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score terrific deals on your flights and hotels by booking ahead.
How to plan a trip to San Luis?
  1. Choose the perfect time to travel: Your schedule, favorite season and the type of weather you like can all influence your decision on when to visit San Luis.
  2. Budget wisely: As well as the price of your accommodations, you'll need to consider other expenses too. These include transportation, food and flights. Also, set aside some extra funds for unexpected expenses that may come up during your trip to San Luis.
  3. Organize your San Luis getaway with Expedia's trip planning tool: Search for and book hotels and activities all in one place. You can also collaborate with friends and family to plan an unforgettable trip to San Luis together.
  4. Decide how long to go for: Now that you're more familiar with San Luis, you can figure out the perfect length of your break. Create a draft plan and allocate enough time to get through everything on your must-do list.
  5. Combine your accommodations and airfare: Once you've settled on your trip dates and duration, book the perfect San Luis vacation package for you.
  6. Book activities and experiences ahead of time: Whether it's entrance to a big attraction or a day trip, you won't have to worry about missing out on the highlights of San Luis. Find all the fun things to do in San Luis with our dedicated travel guide.
Does Expedia offer Book Now, Pay Later San Luis vacation packages?
Your San Luis getaway should be an escape from your busy life, not a source of money worries. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there are no hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.