San Luis Vacations from $389

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The Latest San Luis vacation packages

Price found within the past 48 hours. Click for updated prices.
Sonata 44 Hotel Laureles

Sonata 44 Hotel Laureles

3 out of 5
Laureles
Price was $601, price is now $389 per person
$389
per person
Dec 5 - Dec 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
9/10 Wonderful! (54 reviews)
Excellent service and very clean.

Reviewed on Sep 18, 2024

EP Casa Uribe Architecture Art & Nature

EP Casa Uribe Architecture Art & Nature

4 out of 5
El Poblado
Price was $4,512, price is now $2,264 per person
$2,264
per person
Dec 7 - Dec 12
found 20 hours ago
Roundtrip non-stop flight included
San Juan (SJU) to Medellín (MDE)
10/10 Exceptional! (3 reviews)
The house is extremely comfortable and spacious. Luxury amenities that made us feel at home. The pool, jacuzzi and sauna. Graciela the house keeper and Charles our private chef made our stay amazing. It was nice that they had a lunch and dinner menu available for those days we wanted to stay in. Probably one of the best stays in Medellin. The location is just minutes away from Provenza and surroundings. Manuela the host was super attentive, helping us with reservations at restaurants.

Reviewed on Mar 24, 2025

Autenthico Provenza Hotel Medellin

Autenthico Provenza Hotel Medellin

2 out of 5
El Poblado
Save 100% on your flight
Price was $1,295, price is now $713 per person
$713
per person
Jan 22 - Jan 26
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
9/10 Wonderful! (7 reviews)
Tau House

Tau House

4 out of 5
Save 100% on your flight
Price was $1,152, price is now $661 per person
$661
per person
Dec 11 - Dec 16
found 1 day ago
Roundtrip non-stop flight included
San Juan (SJU) to Medellín (MDE)
9.4/10 Exceptional! (107 reviews)
El hotel muy hermoso! Amamos la privacidad que hay aquí. Y la comida 10/10

Reviewed on Oct 26, 2025

MYLOS Hotel Boutique

MYLOS Hotel Boutique

3 out of 5
Save 100% on your flight
Price was $1,102, price is now $699 per person
$699
per person
Nov 28 - Dec 3
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
6.6/10 (4 reviews)
An amazing experience. The whole staff super friendly. First time in Colombia. For sure I’ll be back. Till the next time

Reviewed on Sep 21, 2025

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Discover the most popular places to visit in San Luis

El Balseadero Nature Park

You can take time to visit El Balseadero Nature Park during your travels to San Luis.

El Balseadero Nature Park

La Planta Waterfall

Commune with nature and explore the great outdoors at La Planta Waterfall during your travels in San Luis.

La Planta Waterfall

What to do in San Luis

Hacienda Napoles - Theme park

Hacienda Napoles - Theme park

$103
per adult
Hacienda Napoles - Theme park
Admission to the Hacienda Naples Theme Park

Visit Hacienda Naples Park by Pablo Escobar

$90
per adult
Visit Hacienda Naples Park by Pablo Escobar
Fun Rafting Adventure and Wonderful Landscapes in Medellin

Fun Rafting Adventure and Wonderful Landscapes in Medellin

$300
per adult
Fun Rafting Adventure and Wonderful Landscapes in Medellin
See all activities in San Luis

San Luis Hotel Deals

The Brown, Guatape, Autograph Collection

The Brown, Guatape, Autograph Collection

4 out of 5
El Peñol - Guatape Paraje, Vereda Los Naranjos, Guatapé, Antioquia
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $166 total per night from Nov 4 to Nov 5
$166 total
Nov 4 - Nov 5
9/10 Wonderful! (376 reviews)
I love this place!! Beyond words, is beautiful. Just note you can’t make too much noice and there is not much to do after 9:30pm.

Reviewed on Oct 26, 2025

The Brown, Guatape, Autograph Collection
Hotel Los Recuerdos

Hotel Los Recuerdos

3.5 out of 5
Via Peñol Gatapé Km 19, Guatapé, Antioquia
$85 nightly
The price is $85 total per night from Oct 30 to Oct 31
$85 total
Oct 30 - Oct 31
8/10 Very Good! (572 reviews)
Not scenic balcony area but it was a great stay.

Reviewed on Oct 20, 2025

Hotel Los Recuerdos
BubbleSky Glamping Guatapé

BubbleSky Glamping Guatapé

3 out of 5
Guatape - El Anillo 3 kms, Ingresando por la piedra, Guatapé, Colombian Peso
Fully refundable
$96 nightly
The price is $96 total per night from Nov 5 to Nov 6
$96 total
Nov 5 - Nov 6
8.8/10 Excellent! (84 reviews)
Great place

Reviewed on Sep 30, 2025

BubbleSky Glamping Guatapé
See all 588 properties in San Luis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best San Luis Vacation Packages

San Luis Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Jose Maria Cordova Intl. Airport (MDE)

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Frequently asked questions

How much does a San Luis vacation package cost?
You can pick up a vacation package to this top destination from $389 on Expedia. But how much your vacation to San Luis costs will depend on factors like the length of stay, hotel choice and season.
What are the cheapest months to go to San Luis?
You're likely to find lower rates and greater availability in November, December and January. Explore our cheap San Luis vacation packages and you could get some great off-season deals.
How many days is enough for San Luis?
Typically, a handful of days is enough to go to the major attractions during your San Luis vacation. But if you want to have some time to rest or take day tours, think about extending your itinerary.
How to find the best San Luis package deals?
Finding a cheap San Luis package deal is a cinch with Expedia. Once you've entered your destination and travel dates under our "Packages" tab, set your maximum budget, apply some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most affordable San Luis package deals. Want a simple trick to score the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book a San Luis vacation as a package?
An Expedia vacation package could land you great savings when compared to booking flights and stays individually. Better still, you can personalize your San Luis trip to match your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to San Luis?
If you're planning an impromptu San Luis vacation, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score terrific deals on your flights and hotels by booking ahead.
How to plan a trip to San Luis?

  1. Choose the perfect time to travel: Your schedule, favorite season and the type of weather you like can all influence your decision on when to visit San Luis.
  2. Budget wisely: As well as the price of your accommodations, you'll need to consider other expenses too. These include transportation, food and flights. Also, set aside some extra funds for unexpected expenses that may come up during your trip to San Luis.
  3. Organize your San Luis getaway with Expedia's trip planning tool: Search for and book hotels and activities all in one place. You can also collaborate with friends and family to plan an unforgettable trip to San Luis together.
  4. Decide how long to go for: Now that you're more familiar with San Luis, you can figure out the perfect length of your break. Create a draft plan and allocate enough time to get through everything on your must-do list.
  5. Combine your accommodations and airfare: Once you've settled on your trip dates and duration, book the perfect San Luis vacation package for you.
  6. Book activities and experiences ahead of time: Whether it's entrance to a big attraction or a day trip, you won't have to worry about missing out on the highlights of San Luis. Find all the fun things to do in San Luis with our dedicated travel guide.

Does Expedia offer Book Now, Pay Later San Luis vacation packages?
Your San Luis getaway should be an escape from your busy life, not a source of money worries. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there are no hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.