San Luis Vacations from $437

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The Latest San Luis vacation packages

Price found within the past 48 hours. Click for updated prices.
Casa Linda Guatapé

Casa Linda Guatapé

$437
per person
Dec 14 - Dec 18
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
7.8/10 Good! (19 reviews)
Makondo House in Provenza by Nowa

Makondo House in Provenza by Nowa

El Poblado
$1,275
per person
Nov 19 - Nov 26
found 1 day ago
Roundtrip non-stop flight included
Santo Domingo (SDQ) to Medellín (MDE)
No reviews
Provenza 5BR Jacuzzi 1 Block from Lleras

Provenza 5BR Jacuzzi 1 Block from Lleras

El Poblado
Save 100% on your flight
$1,027
per person
Nov 19 - Nov 26
found 1 day ago
Roundtrip non-stop flight included
Santo Domingo (SDQ) to Medellín (MDE)
No reviews
Provenza Luxury Residence by HOUSY HOST

Provenza Luxury Residence by HOUSY HOST

El Poblado
Save 100% on your flight
$1,477
per person
Nov 19 - Nov 26
found 1 day ago
Roundtrip non-stop flight included
Santo Domingo (SDQ) to Medellín (MDE)
2/10 (1 review)
The host at the property was staying here as well we put our belongs in the safe and everyday there was 100-150 short so we set a trap for him and left 2k.and the next day there was 50 short,we know contacted the police and we would like some compensation for what has happened.even one time we left a glass half of water and we came back it was full of water

Reviewed on Jan 20, 2025

Luxé Cabañas

Luxé Cabañas

Save 100% on your flight
$740
per person
Dec 14 - Dec 18
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
8.6/10 Excellent! (423 reviews)
Me encantó la vista la propiedad muy limpia

Reviewed on May 28, 2026

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Stay near popular San Luis attractions

El Balseadero Nature Park

You can take time to visit El Balseadero Nature Park during your travels to San Luis.
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La Planta Waterfall

Commune with nature and explore the great outdoors at La Planta Waterfall during your travels in San Luis.
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What to do in San Luis

Hacienda Naples + Colombian Santorini

Hacienda Naples + Colombian Santorini

$140
per adult
Hacienda Naples + Colombian Santorini
Visit Hacienda Naples Theme Park by Pablo Escobar

Visit Hacienda Naples Theme Park by Pablo Escobar

$118
per adult
Visit Hacienda Naples Theme Park by Pablo Escobar
Scenic River Rafting, Swimming & Waterfall Hike

Scenic River Rafting, Swimming & Waterfall Hike

$280
per adult
Scenic River Rafting, Swimming & Waterfall Hike
See all activities in San Luis

San Luis Hotel Deals

Glamping Río Claro

Glamping Río Claro

Autopista Medellín-Bogotá San Luis Antioquia
Fully refundableReserve now, pay when you stay
$53 nightly
$53 total
Oct 27 - Oct 28
10/10 Exceptional! (1 review)
"Todo fue genial! 100% recomendado"

Reviewed on Apr 10, 2026

Glamping Río Claro
The Brown, Guatape, Autograph Collection

The Brown, Guatape, Autograph Collection

El Peñol - Guatape Paraje Guatapé Antioquia
Fully refundableReserve now, pay when you stay
$271 nightly
$271 total
Oct 20 - Oct 21
9.2/10 Wonderful! (563 reviews)
"The Brown Hotel una experiencia que conecta con la naturaleza. Un lugar donde la tranquilidad, la limpieza impecable y la excelente atención se combinan para ofrecerte una estadía inolvidable. Cada detalle invita a desconectarse de la rutina, respirar aire puro y disfrutar de la belleza natural que ..."

Reviewed on Oct 10, 2026

The Brown, Guatape, Autograph Collection
Hotel Los Recuerdos

Hotel Los Recuerdos

Via Peñol Gatapé Km 19 Guatapé Antioquia
Fully refundableReserve now, pay when you stay
$92 nightly
$92 total
Nov 10 - Nov 11
Hotel Los Recuerdos
See all 640 properties in San Luis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best San Luis Vacation Packages

San Luis Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Jose Maria Cordova Intl. Airport (MDE)

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Frequently asked questions

How much does a San Luis vacation package cost?
You can pick up a vacation package to this top destination from $437 on Expedia. But how much your vacation to San Luis costs will depend on factors like the length of stay, hotel choice and season.
What are the cheapest months to go to San Luis?
You're likely to find lower rates and greater availability in November, December and January. Explore our cheap San Luis vacation packages and you could get some great off-season deals.
How many days is enough for San Luis?
Typically, a handful of days is enough to go to the major attractions during your San Luis vacation. But if you want to have some time to rest or take day tours, think about extending your itinerary.
How to find the best San Luis package deals?
Finding a cheap San Luis package deal is a cinch with Expedia. Once you've entered your destination and travel dates under our "Packages" tab, set your maximum budget, apply some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most affordable San Luis package deals. Want a simple trick to score the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book a San Luis vacation as a package?
An Expedia vacation package could land you great savings when compared to booking flights and stays individually. Better still, you can personalize your San Luis trip to match your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to San Luis?
If you're planning an impromptu San Luis vacation, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score terrific deals on your flights and hotels by booking ahead.
How to plan a trip to San Luis?
  1. Choose the perfect time to travel: Your schedule, favorite season and the type of weather you like can all influence your decision on when to visit San Luis.
  2. Budget wisely: As well as the price of your accommodations, you'll need to consider other expenses too. These include transportation, food and flights. Also, set aside some extra funds for unexpected expenses that may come up during your trip to San Luis.
  3. Organize your San Luis getaway with Expedia's trip planning tool: Search for and book hotels and activities all in one place. You can also collaborate with friends and family to plan an unforgettable trip to San Luis together.
  4. Decide how long to go for: Now that you're more familiar with San Luis, you can figure out the perfect length of your break. Create a draft plan and allocate enough time to get through everything on your must-do list.
  5. Combine your accommodations and airfare: Once you've settled on your trip dates and duration, book the perfect San Luis vacation package for you.
  6. Book activities and experiences ahead of time: Whether it's entrance to a big attraction or a day trip, you won't have to worry about missing out on the highlights of San Luis. Find all the fun things to do in San Luis with our dedicated travel guide.
Does Expedia offer Book Now, Pay Later San Luis vacation packages?
Your San Luis getaway should be an escape from your busy life, not a source of money worries. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there are no hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.