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Check prices for these dates

Next weekend
Nov 20 - Nov 22
In two weeks
Nov 27 - Nov 29
In one month
Dec 11 - Dec 13
In two months
Jan 8 - Jan 10
No exact matches found, but these alternatives could be just right

Recommended hotels in Santa Cruz

A hotel entrance with a modern design, glass doors, and a sign reading 'ibis HOTEL'.

1. Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Equipetrol
9.4 out of 10, Exceptional, (159 reviews)
"Good location and value for money."
United States
Hui Hua
$42 nightly
The price is $42
Dec 4 - Dec 5
Ibis Santa Cruz DE LA Sierra
A multi-story hotel with a modern architectural design, featuring a prominent entrance with a red carpet and potted plants.

2. Lido Hotel

Lido Hotel
3.0 star property
Centro Histórico
9.2 out of 10, Wonderful, (58 reviews)
"Lovely stay for a night. Great location within easy walking distance to the center."
United States
Gabrielle
$23 nightly
The price is $23
Nov 20 - Nov 21
Lido Hotel
A modern hotel with a tall, rectangular structure and a glass facade.

3. Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (261 reviews)
"Amazing hotel"
United States
Deivis
$115 nightly
The price is $115
Nov 28 - Nov 29
Marriott Santa Cruz de la Sierra Hotel
The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

4. Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (81 reviews)
"clean close to restaurants friendly staff shop nearby overall excellent place to stay"
United States
Luis
$47 nightly
The price is $47
Nov 14 - Nov 15
Chairú Eco Hotel
A building with a modern architectural design featuring a series of arches and columns.

5. Gran Hotel Santa Cruz

Gran Hotel Santa Cruz
4.5 star property
Centro Histórico
$50 nightly
The price is $50
Nov 20 - Nov 21
Gran Hotel Santa Cruz
A hotel with a prominent 'Hampton' sign, large windows, and a modern facade.

6. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (294 reviews)
"The room was very clean and the breakfast was fantastic. Overall it was a great experience."
United States
Scott
$74 nightly
The price is $74
Nov 14 - Nov 15
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
A building with a sign that reads "COSMOPOLITANO."

7. Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Centro Histórico
9.2 out of 10, Wonderful, (140 reviews)
"Small but beautiful and very much in the center"
United States
Rajendra
$53 nightly
The price is $53
Dec 10 - Dec 11
Cosmopolitano Hotel Boutique
A modern building with a central entrance, flanked by palm trees and a paved pathway leading to the entrance.

8. Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (419 reviews)
"The room and the bed, towels were very clean.The breakfast was very complete and very good."
Canada
Andre Leo
$105 nightly
The price is $105
Nov 20 - Nov 21
Sun Hotel
A multi-story building with a large glass facade, a visible storefront at the ground level, and a clear sky in the background.

9. 518 RENT

518 RENT
3.0 star property
Centro Histórico
$16 nightly
The price is $16
Nov 16 - Nov 17
518 RENT
A modern hotel building with a glass facade, a prominent sign for 'OSHO HOTEL', and a logo with a stylized building and tree.

10. HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (61 reviews)
"Clean room, good staff,"
United States
Neftali
$44 nightly
The price is $44
Nov 13 - Nov 14
HOTEL OSHO
A modern hotel entrance with a curved canopy, large columns, and a well-lit facade.

11. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Equipetrol
9.0 out of 10, Wonderful, (427 reviews)
"I love how nice and helpful staff was."
United States
Lizzie
$161 nightly
The price is $161
Nov 17 - Nov 18
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
A hotel with a unique wavy facade, multiple parking spaces, and a clear blue sky.

12. Hotel Las Américas

Hotel Las Américas
3.0 star property
Centro Histórico
7.8 out of 10, Good, (36 reviews)
"Very clean room and great staff"
Canada
Stanley
$21 nightly
The price is $21
Nov 14 - Nov 15
Hotel Las Américas
A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

13. TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Equipetrol
9.2 out of 10, Wonderful, (186 reviews)
"Beautiful hotel. Spacious room. House cleaning came every day. We got new towels every day and toiletries in the bathroom were refilled every day. Staff were friendly. View from the breakfast room was beautiful. Location of the hotel is good."
Canada
Kristina
$69 nightly
The price is $69
Nov 13 - Nov 14
TRYP by Wyndham Santa Cruz
A hotel entrance with a glass door, a large logo, and a well-maintained garden.

14. Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (112 reviews)
"Excelente Hotel "
Mexico
JACOB
$21 nightly
The price is $21
Dec 12 - Dec 13
Hotel G
A multi-story hotel with balconies, air conditioning units, and a storefront with signage.

15. Gran Hotel Mediterráneo

Gran Hotel Mediterráneo
3.5 star property
Centro Histórico
10.0 out of 10, Exceptional, (1 review)
"Desde a recepção, a equipe da limpeza e o pessoal do café da manhã, foram sempre muito prestativos e disponíveis para ajudar no que foi necessário, voltaremos. A localização é bem próxima a praça central."
Brazil
Emerson
$55 nightly
The price is $55
Nov 13 - Nov 14
Gran Hotel Mediterráneo
A historic building with two prominent towers and a plaza with outdoor seating.

16. Hotel Pascana centro

Hotel Pascana centro
3.5 star property
Centro Histórico
9.4 out of 10, Exceptional, (3 reviews)
"El hotel se encuentra en el Centro histórico de la ciudad, es una estructura dentro del marco historico de la ciudad, pero se encuentra en buenas condiciones. Con facil acceso al transporte. Camina el centro de la ciudad histórica con tranquilidad."
United States
Miguel
$63 nightly
The price is $63
Nov 18 - Nov 19
Hotel Pascana centro
A modern two-story building with large windows, a flat roof, and a minimalist design.

17. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (121 reviews)
"great place to stay!"
United States
Luisa
$46 nightly
The price is $46
Nov 13 - Nov 14
Premium Suites Deluxe Aparthotel Equipetrol
A multi-story hotel with balconies and a prominent sign for 'Premio Suites Apart Hotel'.

18. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (107 reviews)
"Great location."
United States
Ruben
$22 nightly
The price is $22
Nov 15 - Nov 16
Apart Hotel Premium Suites Santa Cruz
A building with large windows, a brick facade, and a covered entrance area.

19. Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (457 reviews)
"The food is excellent quality and delicious! Friendly staff"
United States
Wendy
$122 nightly
The price is $122
Dec 6 - Dec 7
Camino Real Hotel
A modern building with a stone facade and large windows. The name 'DEFINES COLLECTION' is prominently displayed on the building.

20. Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Equipetrol
9.0 out of 10, Wonderful, (103 reviews)
"Great location, nice and quiet neighborhood."
United States
ALEJANDRO
$48 nightly
The price is $48
Nov 26 - Nov 27
Delfines Collection Hotel By Mercure
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.

Top reviews in Santa Cruz

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.
Chairú Eco Hotel

Chairú Eco Hotel

Chairú Eco Hotel
Santa Cruz

10/10 Excellent

Nice and clean
United States
Brian
Reviewed October 28, 2026
Chairú Eco Hotel

Frequently Asked Questions

What are the best cabins near Santa Cruz?

Settle into one of our 2 cabins in Santa Cruz and you'll be rewarded with beautiful scenery, outdoor adventure and memories you'll never forget. Cabin - Quinta Piray promises a slower pace of life. Quinta Villa Rosario is another great choice if you're eager to relax in Mother Nature.

Are there cheap cabins in Santa Cruz?

For an unforgettable getaway in the great outdoors, you can't top our cheap cabins in Santa Cruz. Wake up to the sound of birdsong from one of our cozy cabins priced from $16 to $160 per night.

These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best cabin prices in Santa Cruz?

With prices starting from just $16 a night for a cabin rental in Santa Cruz, there's no reason to wrestle with that hard-to-pitch tent.

What are the top things to see and do in Santa Cruz?

We get how tempting it is to put your feet up and relax, but there's an incredible world to explore outside your wonderfully cozy cabin. For instance, Plaza 24 de Septiembre, Ventura Mall and Santa Cruz Zoo. They're some major highlights around Santa Cruz. If you'd like some more sightseeing ideas, Guembe Biocenter, Lomas de Arena Regional Park and Municipal Botanical Garden of Santa Cruz await a little farther out.

Why should I book a cabin in Santa Cruz?

Affordability, rustic charm, nature-filled surroundings — there are plenty of good reasons to stay in a Santa Cruz cabin. Get away from the noise of the concrete jungle and rise with the sound of songbirds and wildlife. There's so much adventure on your doorstep too. Whether you're taking a break with family, friends or your sweetie, you'll locate the perfect cabin on Expedia.