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Our top choices for Santa Fe Depot vacation homes

Capitol House - Historic 5bed/3bath house near OUHSC,State Capitol and Downtown

Capitol House - Historic 5bed/3bath house near OUHSC,State Capitol and Downtown
Central Oklahoma City
10.0 out of 10, Exceptional, (118)
"We needed a place to stay while our home went through some repairs and while our oldest son receives treatment at Oklahoma City Children's Hospital for a rare cancer. This place was close, clean and affordable for our entire family!"
United States
Christina P.
Capitol House - Historic 5bed/3bath house near OUHSC,State Capitol and Downtown

Casa Mahogany - East Bricktown's Contemporary Gem. HOT TUB!

Casa Mahogany - East Bricktown's Contemporary Gem. HOT TUB!
Central Oklahoma City
9.8 out of 10, Exceptional, (39)
"Great place, location, and communication! Would definitely recommend to others and would book again. "
United States
Amanda S.
Casa Mahogany - East Bricktown's Contemporary Gem. HOT TUB!

Newly Renovated Villa|🚶1min from Plaza District|Hot Tub|🎱Pool Table|🐶Friendly

Newly Renovated Villa|🚶1min from Plaza District|Hot Tub|🎱Pool Table|🐶Friendly
Central Oklahoma City
9.2 out of 10, Wonderful, (19)
"The kitchen was well equipped, property was clean, and just what we need for our two small dogs."
United States
Casey H.
$452 nightly
The price is $523
Dec 18 - Dec 19
Total with taxes and fees
Newly Renovated Villa|🚶1min from Plaza District|Hot Tub|🎱Pool Table|🐶Friendly

Cozy 2-bedroom, 2-bath house in charming Oklahoma City

Cozy 2-bedroom, 2-bath house in charming Oklahoma City
Central Oklahoma City
10.0 out of 10, Exceptional, (1)
"We thoroughly enjoyed our stay in this very clean and nicely done bungalow. It was centrally located to all we had planned. It was quiet and comfortable, with good AC, ceiling fans and comfortable furnishings. The listing was missing a few things I found on another site but I have seen that with VRBO before and do not fault the owner. The owner was extremely responsive to all queries, even late at night. Overall, it was a very good stay and we will definitely stay again when we return for...
United States
Eileen K.
Cozy 2-bedroom, 2-bath house in charming Oklahoma City

Beautiful 4 Bed House With King Bed & HOA Park

Beautiful 4 Bed House With King Bed & HOA Park
Central Oklahoma City
9.2 out of 10, Wonderful, (12)
"Very convenient to the OUHSC. Close access to midtown and downtown as well. Good communication with the hosts and having a garage was a nice bonus. "
United States
Kendra H.
Beautiful 4 Bed House With King Bed & HOA Park

Spacious 4 Bed House With King Bed & Playground

Spacious 4 Bed House With King Bed & Playground
Central Oklahoma City
9.6 out of 10, Exceptional, (11)
"Great property, clean, comfy beds...everything we needed...and the communication was excellent!"
United States
Katrina P.
$312 nightly
The price is $312
Dec 15 - Dec 16
Total with taxes and fees
Spacious 4 Bed House With King Bed & Playground

Midtown Historic Bungalow

Midtown Historic Bungalow
2.0 star property
Central Oklahoma City
10.0 out of 10, Exceptional, (4)
"We loved our weekend stay at this cute little house!"
United States
Meghan K.
Midtown Historic Bungalow

Beautifully Remodeled 3B1.5B W/ King Bed By OU Med

Beautifully Remodeled 3B1.5B W/ King Bed By OU Med
Central Oklahoma City
9.4 out of 10, Exceptional, (11)
"Great stay! Very very good communication with host!"
United States
Mike S.
Beautifully Remodeled 3B1.5B W/ King Bed By OU Med

Cozy Craftsman Bungalow in the heart of downtown OKC with AC, Workspace, Parking

Cozy Craftsman Bungalow in the heart of downtown OKC with AC, Workspace, Parking
Central Oklahoma City
10.0 out of 10, Exceptional, (7)
"It was a good overall experience for a family with kids to stay in this property. Thanks Colten!!!"
United States
sugumar r.
Cozy Craftsman Bungalow in the heart of downtown OKC with AC, Workspace, Parking

"The Ivyson" on 10th Urban Core Midtown OKC

"The Ivyson" on 10th Urban Core Midtown OKC
Central Oklahoma City
6.0 out of 10, (1)
"The place looked just like the pictures. Nicely decorated and very clean. The downstairs bed is bigger than it looks in the picture. My two teen girls slept in it just fine. My only complaint is it smelled like someone had smoked weed in the house. It gave two of us really bad headaches and one of my kids got sick to her stomach from it. Overall we loved the place…except the weed smell! "
United States
Julie N.
$297 nightly
The price is $343
Dec 14 - Dec 15
Total with taxes and fees
"The Ivyson" on 10th Urban Core Midtown OKC

Quiet 4 Bed Home With HOA Park

Quiet 4 Bed Home With HOA Park
Central Oklahoma City
8.8 out of 10, Excellent, (5)
"This VRBO was clean and quiet. Cute space "
United States
Kristen M.
Quiet 4 Bed Home With HOA Park

Modern OKC Retreat: Half-Mile to Plaza District!

Modern OKC Retreat: Half-Mile to Plaza District!
Central Oklahoma City
10.0 out of 10, Exceptional, (4)
"We had great communication from our host. We found the house stocked with everything we needed."
United States
Nancy W.
Modern OKC Retreat: Half-Mile to Plaza District!

Velvet studio apartment located in Deep Duece.

Velvet studio apartment located in Deep Duece.
2.0 star property
Downtown Oklahoma City
9.6 out of 10, Exceptional, (10)
"Great location and very cute apartment"
United States
DUSTYN ROSE
Velvet studio apartment located in Deep Duece.

Howes Capitol–3 in 1-near OU Med, Bricktown, Arena

Howes Capitol–3 in 1-near OU Med, Bricktown, Arena
Central Oklahoma City
9.2 out of 10, Wonderful, (7)
"Recommend this listing for families who would like the 3 seperate duplexes / apartments all next to each other (would not recommend for an individual family that does not want to sleep separately from kids, etc). All 3 were extremely comfortable and spacious, next to each other and right in the heart of Oklahoma City."
Australia
Gabbi L.
$594 nightly
The price is $627
Dec 14 - Dec 15
Total with taxes and fees
Howes Capitol–3 in 1-near OU Med, Bricktown, Arena

Blue Bungalow near OU Med/Downtown 0 cleaning fee

Blue Bungalow near OU Med/Downtown 0 cleaning fee
Central Oklahoma City
8.8 out of 10, Excellent, (9)
"I would recommend this stay to whomever has business or visiting family. House was just as described as in the site. It close to Oklahoma University. If you up for a bit of nostalgia, they have an old Airsteam you can sleep in. I was extremely impressed with this home. Would recommend. "
United States
Kenneth V.
Blue Bungalow near OU Med/Downtown 0 cleaning fee

Entire Lincoln Lodge by OU Medical

Entire Lincoln Lodge by OU Medical
Central Oklahoma City
9.6 out of 10, Exceptional, (14)
"Love the property! Very clean, nicely decorated, quiet neighborhood. All the basics were supplied and everything was very very comfortable, but don’t look for luxury bedding if that’s your thing. Tons of space for everyone. Huge bonus: you don’t have to spend the morning of checkout stripping beds, mopping floors, cleaning bathrooms, etc. They do all that!!! Amazing and made things stress free. Would definitely stay again! "
United States
J L.
Entire Lincoln Lodge by OU Medical

Casa Rivera Uptown with 2 king beds

Casa Rivera Uptown with 2 king beds
Central Oklahoma City
$320 nightly
The price is $370
Dec 14 - Dec 15
Total with taxes and fees
Casa Rivera Uptown with 2 king beds

Upscale living in Downtown OKC. Unbeatable location and pet friendly!

Upscale living in Downtown OKC. Unbeatable location and pet friendly!
Downtown Oklahoma City
2.0 out of 10, (1)
"Got confirmation at booking and 48 hours prior to check in. Then no door code, 3 hours before anyone could get ahold of owner who had no knowledge of booking. I had to get another room. "
United States
Dan D.
Upscale living in Downtown OKC. Unbeatable location and pet friendly!

Chic 50s Time Capsule Downtown/OU Med/OK Capitol

Chic 50s Time Capsule Downtown/OU Med/OK Capitol
Central Oklahoma City
9.8 out of 10, Exceptional, (11)
"Fun place to stay!"
United States
Christina F.
$163 nightly
The price is $189
Dec 15 - Dec 16
Total with taxes and fees
Chic 50s Time Capsule Downtown/OU Med/OK Capitol

Brick View Studio in downtown Oklahoma City

Brick View Studio in downtown Oklahoma City
2.0 star property
Downtown Oklahoma City
Brick View Studio in downtown Oklahoma City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Fe Depot Hotel Reviews

Find out more about Santa Fe Depot

What types of Vacation Homes can I find in Santa Fe Depot?

At Expedia, you’ll find great Santa Fe Depot Vacation Homes for your family vacation, business trip, romantic weekend break, and more. If you’re planning a vacation with kids, try using the traveler experience filter to select “Family-friendly” Santa Fe Depot Vacation Homes. Or, if you’re traveling for work, you can check the “Business-friendly” box to find business-oriented places to stay in Santa Fe Depot. While you’re making your decision, you can use our map facility to view your shortlisted properties and their distance from Santa Fe Depot, or nearby places of interest. There are great places to stay for every budget, so if you need cheap Vacation Homes in Santa Fe Depot, use our simple search function to help you secure a great deal.

How much do Vacation Homes cost in Santa Fe Depot?

The price per night for Santa Fe Depot Vacation Homes in 2026 can start from as low as *. The cost of Vacation Homes varies depending on a number of factors: the dates of your stay, the exact location of the accommodation, and whether there are any special events taking place near Santa Fe Depot, to name just three. When there’s a high demand for rooms in Santa Fe Depot, this can cause prices to increase, whereas traveling during a quieter time of the year can mean lower prices. Booking through Expedia can help you find some of the best deals for cheap Vacation Homes in Santa Fe Depot, so you can sleep easy without going over your budget.

How to find the best deals on Santa Fe Depot Vacation Homes?

Expedia’s search function can help you find some of the best deals on Santa Fe Depot Vacation Homes. You can select a minimum and maximum price per night according to your budget, and filter by guest ratings and star ratings to ensure you find the right Vacation Homes for your needs. Changing the sort order according to price can also help you to view cheap Vacation Homes in Santa Fe Depot at a glance, and you can combine this with our own picks to highlight some of the best available offers. Don’t forget, if you’re an Expedia Rewards member, you can use the “Member Prices” filter to make extra savings on your booking.

Why should I choose Expedia to book Santa Fe Depot Vacation Homes?

Booking with Expedia allows you to browse a wide selection of places to stay in Santa Fe Depot, complete with search filters that make it easy to locate Vacation Homes that best meet your specific requirements. Our clear and easy-to-use search function makes it effortless to compare amenities, prices, property types, neighborhoods, and much more. At Expedia, you can also find flights, car rental, and activities, and you can combine your bookings for greater savings. Plus, Expedia Rewards members accrue points on all eligible purchases. Build your points total to gain discounts on subsequent bookings in the future. Membership is free, so go ahead and join.

What is the cancellation policy on booking Santa Fe Depot Vacation Homes?

At Expedia, we understand that plans change, and the good news is you can cancel many bookings for Santa Fe Depot Vacation Homes with a full refund, depending on the rules and restrictions. For example, some Vacation Homes may not give refunds if you cancel your booking within 24 or 48 hours of your arrival date, and some bookings are non-refundable. Be sure to view the policies provided by the Santa Fe Depot Vacation Homes, and confirm the exact cancellation window on your selected location’s details page. If free cancellation is important to you, you can filter for the “Fully refundable” payment type when you search for your Vacation Homes.

*Prices and availability are subject to change. Additional terms may apply 

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