Santa Maria de Jesus Vacations from $811

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Your Santa Maria de Jesus Vacation

Lock in a Santa Maria de Jesus vacation package and get set to experience this captivating city the easy way. Consider staying in the neighborhood of Santa Ana, which is good for culture and history. Make your trip to Santa Maria de Jesus even more exciting by including some sightseeing. Casa Santo Domingo Museum, Central Park and Santa Catalina Arch are among the most popular attractions you'll want to explore. Check out Expedia's extensive range of travel options and begin planning your dream vacation to Santa Maria de Jesus today.

The Latest Santa Maria de Jesus vacation packages

Price found within the past 48 hours. Click for updated prices.
Atitlan Oasis Eco Hotel and Spa Kaalpul

Atitlan Oasis Eco Hotel and Spa Kaalpul

3.5 out of 5
Price was $1,097, price is now $811 per person
$811
per person
Jan 27 - Feb 1
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Guatemala City (GUA)
8.6/10 Excellent! (92 reviews)
Had a fantastic time, super helpful in how to get to the resort. Will definitely be back in the future.

Reviewed on Nov 8, 2026

Hotel Casa Ki'iil San Juan La Laguna

Hotel Casa Ki'iil San Juan La Laguna

2 out of 5
Price was $2,016, price is now $1,270 per person
$1,270
per person
Dec 27 - Jan 3
found 1 hour ago
Roundtrip flight included
Atlanta (ATL) to Guatemala City (GUA)
9.2/10 Wonderful! (46 reviews)
Rosario and the groundskeeper Pancho were Amazingly helpful and the Location was perfect to visit San Marcos and San Pedro!!! The room was cute and the View was Beautiful :)

Reviewed on Sep 24, 2026

Kula Maya Boutique Hotel & Spa

Kula Maya Boutique Hotel & Spa

5 out of 5
Save 100% on your flight
Price was $1,650, price is now $1,147 per person
$1,147
per person
Jan 27 - Feb 1
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Guatemala City (GUA)
9.4/10 Exceptional! (182 reviews)

Villas La Mar

Villas La Mar

4 out of 5
Price was $1,573, price is now $1,119 per person
$1,119
per person
Jan 15 - Jan 18
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Guatemala City (GUA)
8.2/10 Very Good! (151 reviews)
Excellent

Reviewed on Nov 2, 2026

Hotel Paz en la Tormenta Tejar - Hostel

Hotel Paz en la Tormenta Tejar - Hostel

2 out of 5
Price was $6,540, price is now $4,841 per person
$4,841
per person
Dec 27 - Jan 3
found 1 hour ago
Roundtrip flight included
Atlanta (ATL) to Guatemala City (GUA)
No reviews

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Stay near popular Santa Maria de Jesus attractions

Cerro Monterrico

Commune with nature and explore the great outdoors at Cerro Monterrico during your travels in Santa Maria de Jesus.
See properties

What to do in Santa Maria de Jesus

Picture 1 for Activity From Antigua: Pacaya Volcano Trek

From Antigua: Pacaya Volcano Trek

$23
per adult
90% of travellers recommend
From Antigua: Pacaya Volcano Trek
From Antigua: Pacaya Volcano Tour in English/Spanish

From Antigua: Pacaya Volcano Tour in English/Spanish

$23
per adult
78% of travellers recommend
From Antigua: Pacaya Volcano Tour in English/Spanish
Picture 1 for Activity From Antigua: Adventure, 2-Day Hiking to Acatenango Volcano

From Antigua: Adventure, 2-Day Hiking to Acatenango Volcano

$57
per adult
From Antigua: Adventure, 2-Day Hiking to Acatenango Volcano
See all activities in Santa Maria de Jesus

Santa Maria de Jesus Hotel Deals

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $131 total per night from Dec 7 to Dec 8
$131 total
Dec 7 - Dec 8
Total with taxes and fees
Barceló Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
$325 nightly
The price is $404 total per night from Dec 13 to Dec 14
$404 total
Dec 13 - Dec 14
Total with taxes and fees
9.4/10 Exceptional! (1,199 reviews)
"Beautiful property, beautiful spa, amazing food and service!"

Reviewed on Nov 11, 2026

Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $150 total per night from Nov 29 to Nov 30
$150 total
Nov 29 - Nov 30
Total with taxes and fees
Wyndham Garden Guatemala City
See all 1,304 properties in Santa Maria de Jesus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Maria de Jesus Vacation Packages

Santa Maria de Jesus Essential Information

Language
Spanish
Currency
Guatemalan quetzals
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
La Aurora Intl. Airport (GUA)
Population
15,500
Top Sights
Antigua Guatemala Cathedral, Volcan de Fuego and Volcan de Agua

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Frequently asked questions

How much does a Santa Maria de Jesus vacation package cost?
You can pick up a vacation package to this top destination from $811 on Expedia. But how much your vacation to Santa Maria de Jesus costs will depend on your hotel choice, season and length of stay.
What are the cheapest months to go to Santa Maria de Jesus?
December, January and February are the best times to look for cheap Santa Maria de Jesus vacation packages. Opting to travel in quieter months means you can usually find lower prices on flights and hotels.
How many days is enough for Santa Maria de Jesus?
The ideal duration of your Santa Maria de Jesus vacation depends on what you'd like to see and do. Usually, a handful of days to a week will give you plenty of time to tick off all the major sights and explore some hidden spots along the way.
How to find the best Santa Maria de Jesus package deals?
Begin your search for a Santa Maria de Jesus package deal by entering your preferred travel dates and destination under our "Packages" tab. Then select a few filters, like "Popular locations" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santa Maria de Jesus package deal right away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Maria de Jesus adventure off to a flying start.
Is it cheaper to book a Santa Maria de Jesus vacation as a package?
You can enjoy significant savings on your next Santa Maria de Jesus getaway by booking a customized vacation package. Check the "Package" heading, then enter your travel dates and destination to browse the best airfares and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Santa Maria de Jesus?
If you've got your Santa Maria de Jesus vacation dates locked in, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spur-of-the-moment getaways? Our last-minute deals are perfect for impromptu escapes.
How to plan a trip to Santa Maria de Jesus?

  1. Choose your travel dates: What you'd like to do in Santa Maria de Jesus and your favorite season can help you decide when to go.
  2. Set your budget: Consider costs such as transportation, flights and meals when calculating how much to put aside for your trip to Santa Maria de Jesus. Then, select a property that suits your budget, whether that's a wallet-friendly stay or a more upscale getaway.
  3. Use our trip planning tool to discover Santa Maria de Jesus: Research every aspect of your trip to Santa Maria de Jesus with this handy planner. Invite family or friends to collaborate on a group trip, search for hotels or things to do and make bookings.
  4. Decide how many days away: Start by listing all the activities and attractions you'd like to get to in Santa Maria de Jesus. Then, estimate how long you'll need for each, including any travel time.
  5. Combine your flights and hotel: Awesome destination, check. Length of stay, check. All that's left is to pick a Santa Maria de Jesus vacation package that brings all your bookings together.
  6. Book experiences or activities ahead of time: Whether it's entrance to a major attraction or a walking tour, you won't have to worry about missing out on Santa Maria de Jesus's highlights. Find all the fun things to do in Santa Maria de Jesus with our dedicated activity guide.

Does Expedia offer Book Now, Pay Later Santa Maria de Jesus vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your Santa Maria de Jesus vacation across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.