Santa Maria de Jesus Vacations from $1,185

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Santa Maria de Jesus Vacation

Lock in a Santa Maria de Jesus vacation package and get set to experience this captivating city the easy way. Consider staying in the neighborhood of Santa Ana, which is good for culture and history. Make your trip to Santa Maria de Jesus even more exciting by including some sightseeing. Casa Santo Domingo Museum, Central Park and Santa Catalina Arch are among the most popular attractions you'll want to explore. Check out Expedia's extensive range of travel options and begin planning your dream vacation to Santa Maria de Jesus today.

The Latest Santa Maria de Jesus vacation packages

Price found within the past 48 hours. Click for updated prices.
Royal Decameron Salinitas - All Inclusive

Royal Decameron Salinitas - All Inclusive

$1,185
per person
Nov 5 - Nov 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Guatemala City (GUA)
7/10 Good! (1,105 reviews)
.

Reviewed on Sep 28, 2026

Hotel Soleil La Antigua

Hotel Soleil La Antigua

$1,549
per person
Nov 28 - Dec 5
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Guatemala City (GUA)
8.8/10 Excellent! (1,000 reviews)
The property is spacious and well maintained. The view of the Volcano de Agua is a plus. Staff was very helpful. More attention to some details could make the difference for some travelers but overall, good for the price. They recently upgraded the lobby’s furniture; colorful and lovely. I wish they could offer night entertainment other than karaoke, maybe invite marimba groups, dancers, authentic arts and crafts nights, etc.

Reviewed on Sep 26, 2026

Villas La Mar

Villas La Mar

$1,259
per person
Nov 4 - Nov 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Guatemala City (GUA)
8.2/10 Very Good! (150 reviews)
Hotel Casa Palopó - Relais & Chateaux

Hotel Casa Palopó - Relais & Chateaux

Save 100% on your flight
$2,478
per person
Dec 11 - Dec 15
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guatemala City (GUA)
9.2/10 Wonderful! (275 reviews)
Good Hotel Antigua Guatemala, a Member of Design Hotels

Good Hotel Antigua Guatemala, a Member of Design Hotels

$1,375
per person
Nov 21 - Nov 26
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Guatemala City (GUA)
9.2/10 Wonderful! (568 reviews)
Don't see what you're looking for?
See all available trips from Columbus to Santa Maria de Jesus
View all trips

Stay near popular Santa Maria de Jesus attractions

Cerro Monterrico

Commune with nature and explore the great outdoors at Cerro Monterrico during your travels in Santa Maria de Jesus.
See properties

What to do in Santa Maria de Jesus

From Antigua: Pacaya Volcano Tour in English/Spanish

From Antigua: Pacaya Volcano Tour in English/Spanish

$23
per adult
88% of travellers recommend
From Antigua: Pacaya Volcano Tour in English/Spanish
From Antigua: 2-Day Acatenango Volcano Hiking Tour with Food

From Antigua: 2-Day Acatenango Volcano Hiking with Guide

$57
per adult
From Antigua: 2-Day Acatenango Volcano Hiking with Guide
Picture 1 for Activity From Antigua: Adventure, 2-Day Hiking to Acatenango Volcano

From Antigua: Adventure, 2-Day Hiking to Acatenango Volcano

$57
per adult
From Antigua: Adventure, 2-Day Hiking to Acatenango Volcano
See all activities in Santa Maria de Jesus

Santa Maria de Jesus Hotel Deals

Barceló Guatemala City

Barceló Guatemala City

7 Avenida 15-45, Zona 9 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
$99 nightly
$121 total
Oct 4 - Oct 5
Total with taxes and fees
9.2/10 Wonderful! (3,309 reviews)
"This hotel was perfect for our stay. The staff were very helpful and attentive as needed. Definitely would recommend to stay here."

Reviewed on Sep 28, 2026

Barceló Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
Fully refundableReserve now, pay when you stay
$248 nightly
$303 total
Sep 29 - Sep 30
Total with taxes and fees
Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

1a Avenida 12-46 Zona 10 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
$105 nightly
$129 total
Oct 24 - Oct 25
Total with taxes and fees
Wyndham Garden Guatemala City
See all 1,298 properties in Santa Maria de Jesus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Maria de Jesus Vacation Packages

Santa Maria de Jesus Essential Information

Language
Spanish
Currency
Guatemalan quetzals
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
La Aurora Intl. Airport (GUA)
Population
15,500
Top Sights
Antigua Guatemala Cathedral, Volcan de Fuego and Volcan de Agua

More vacations you might like

Frequently asked questions

How much does a Santa Maria de Jesus vacation package cost?
You can pick up a vacation package to this top destination from $1,185 on Expedia. But how much your vacation to Santa Maria de Jesus costs will depend on your hotel choice, season and length of stay.
What are the cheapest months to go to Santa Maria de Jesus?
December, January and February are the best times to look for cheap Santa Maria de Jesus vacation packages. Opting to travel in quieter months means you can usually find lower prices on flights and hotels.
How many days is enough for Santa Maria de Jesus?
The ideal duration of your Santa Maria de Jesus vacation depends on what you'd like to see and do. Usually, a handful of days to a week will give you plenty of time to tick off all the major sights and explore some hidden spots along the way.
How to find the best Santa Maria de Jesus package deals?
Begin your search for a Santa Maria de Jesus package deal by entering your preferred travel dates and destination under our "Packages" tab. Then select a few filters, like "Popular locations" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santa Maria de Jesus package deal right away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Maria de Jesus adventure off to a flying start.
Is it cheaper to book a Santa Maria de Jesus vacation as a package?
You can enjoy significant savings on your next Santa Maria de Jesus getaway by booking a customized vacation package. Check the "Package" heading, then enter your travel dates and destination to browse the best airfares and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Santa Maria de Jesus?
If you've got your Santa Maria de Jesus vacation dates locked in, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spur-of-the-moment getaways? Our last-minute deals are perfect for impromptu escapes.
How to plan a trip to Santa Maria de Jesus?
  1. Choose your travel dates: What you'd like to do in Santa Maria de Jesus and your favorite season can help you decide when to go.
  2. Set your budget: Consider costs such as transportation, flights and meals when calculating how much to put aside for your trip to Santa Maria de Jesus. Then, select a property that suits your budget, whether that's a wallet-friendly stay or a more upscale getaway.
  3. Use our trip planning tool to discover Santa Maria de Jesus: Research every aspect of your trip to Santa Maria de Jesus with this handy planner. Invite family or friends to collaborate on a group trip, search for hotels or things to do and make bookings.
  4. Decide how many days away: Start by listing all the activities and attractions you'd like to get to in Santa Maria de Jesus. Then, estimate how long you'll need for each, including any travel time.
  5. Combine your flights and hotel: Awesome destination, check. Length of stay, check. All that's left is to pick a Santa Maria de Jesus vacation package that brings all your bookings together.
  6. Book experiences or activities ahead of time: Whether it's entrance to a major attraction or a walking tour, you won't have to worry about missing out on Santa Maria de Jesus's highlights. Find all the fun things to do in Santa Maria de Jesus with our dedicated activity guide.
Does Expedia offer Book Now, Pay Later Santa Maria de Jesus vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your Santa Maria de Jesus vacation across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.