Title: Santa Maria de Jesus Vacation Rentals from $44: Search Short-Term Rentals | Expedia.com [Santa Maria de Jesus Travel Guide](https://expedia.com/Santa-Maria-De-Jesus.dx3000472642)[Hotels in Santa Maria de Jesus](https://expedia.com/Santa-Maria-De-Jesus-Hotels.d3000472642.Travel-Guide-Hotels)[Flights to Santa Maria de Jesus](https://expedia.com/Cheap-Flights-To-Santa-Maria-De-Jesus.d3000472642.Travel-Guide-Flights)[Things to do in Santa Maria de Jesus](https://expedia.com/Things-To-Do-In-Santa-Maria-De-Jesus.d3000472642.Travel-Guide-Activities)[Car Rentals in Santa Maria de Jesus](https://expedia.com/Car-Rentals-In-Santa-Maria-De-Jesus.d3000472642.Car-Rental-Guide)[Santa Maria de Jesus Vacation Packages](https://expedia.com/Santa-Maria-De-Jesus.d3000472642.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=3000472642&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=3000472642&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=3000472642&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 17 - Jul 19](https://www.expedia.com/Hotel-Search?regionId=3000472642&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Maria de Jesus vacation rentals ![1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113470000/113462400/113462385/9a0da130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/114000000/113470000/113462400/113462385/407f6115.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113470000/113462400/113462385/ea8a8ed6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/114000000/113470000/113462400/113462385/448460e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peaceful Cabin Near Antigua Guatemala with Farm Animals to connect with nature [](https://www.expedia.com/Santiago-Sacatepequez-Hotels-Peaceful-Cabin-Near-Antigua-Guatemala-With-Farm-Animals-To-Connect-With-Nature.h113462385.Hotel-Information) San Lucas Sacatepéquez $74 nightly $74 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Santiago-Sacatepequez-Hotels-Peaceful-Cabin-Near-Antigua-Guatemala-With-Farm-Animals-To-Connect-With-Nature.h113462385.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19490000/19485700/19485634/2ca83340.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/20000000/19490000/19485700/19485634/11b4b067.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/20000000/19490000/19485700/19485634/8a782fda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment Near Guatemala City With Nice View [](https://www.expedia.com/Guatemala-City-Hotels-Apartment-Near-Guatemala-City-With-Nice-View.h19485634.Hotel-Information) mixco $65 nightly $65 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Guatemala-City-Hotels-Apartment-Near-Guatemala-City-With-Nice-View.h19485634.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/119000000/118170000/118165100/118165071/a6e22a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/119000000/118170000/118165100/118165071/1819f19c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/119000000/118170000/118165100/118165071/4eeb09d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118170000/118165100/118165071/9c35cfe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Roosevelt Apartment [](https://www.expedia.com/Guatemala-City-Hotels-Roosevelt-Apartment.h118165071.Hotel-Information) Zona 2 de Mixco 10/10 Exceptional (1 review) "Good" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Alfredo $79 nightly $79 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/Guatemala-City-Hotels-Roosevelt-Apartment.h118165071.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34660000/34657300/34657250/e6463826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34660000/34657300/34657250/9298138e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/35000000/34660000/34657300/34657250/bda5b663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34660000/34657300/34657250/f19b40ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfortable cabin in Guatemala [](https://www.expedia.com/San-Jose-Pinula-Hotels-Comfortable-Cabin-In-Guatemala.h34657250.Hotel-Information) San José Pinula $145 nightly $145 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/San-Jose-Pinula-Hotels-Comfortable-Cabin-In-Guatemala.h34657250.Hotel-Information) ![Basic Apartment, 2 Bedrooms, Balcony, City View | Private kitchen | Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/123000000/122670000/122667600/122667551/39facc09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/123000000/122670000/122667600/122667551/f302d6fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/123000000/122670000/122667600/122667551/w1062h1077x9y3-63fbc3e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/123000000/122670000/122667600/122667551/891bf194.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### L AURORA INN Apart [](https://www.expedia.com/Guatemala-City-Hotels-L-AURORA-INN-Apart.h122667551.Hotel-Information) Zona 13 7.6/10 Good (21 reviews) "Very nice place and amazing service. I will definitely stay there with my family in the future. I love the place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Braulio $81 nightly $100 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Guatemala-City-Hotels-L-AURORA-INN-Apart.h122667551.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/125000000/124900000/124897600/124897551/899eb3fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124900000/124897600/124897551/3cf6dcf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/125000000/124900000/124897600/124897551/cfa0493a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/125000000/124900000/124897600/124897551/74d09509.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carmelo Concept Villas, Villa 1 [](https://www.expedia.com/Antigua-Guatemala-Hotels-Carmelo-Concept-Villas.h124897551.Hotel-Information) Antigua Guatemala $286 nightly $286 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Antigua-Guatemala-Hotels-Carmelo-Concept-Villas.h124897551.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/125000000/124860000/124854800/124854717/b6cc23a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/125000000/124860000/124854800/124854717/ce992daf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124860000/124854800/124854717/15199f45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124860000/124854800/124854717/w1024h647x0y18-bb8120e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### LUXURY HOME - CASA LAVA, PANORAMIC VIEWS OF VOLCAN DE FUEGO [](https://www.expedia.com/Ciudad-Vieja-Hotels-LUXURY-HOME-CASA-LAVA.h124854717.Hotel-Information) Ciudad Vieja 10/10 Exceptional (1 review) "This was a much needed property after returning from our hike in Acatenango. Unique, high end finishes and amenities. The linens and personalized body washes/soaps smell AMAZING. The personal chef is so friendly and the food was great. I love the view of Fuego right outside the master’s bedroom window, you can see the eruptions!! This is a fairly new property with a gated entrance into what I believe is an upcoming community. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Krystal D. $689 nightly $689 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Ciudad-Vieja-Hotels-LUXURY-HOME-CASA-LAVA.h124854717.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/113000000/112590000/112587800/112587752/e13eec14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112590000/112587800/112587752/e0a1bd74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112590000/112587800/112587752/6015c499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/113000000/112590000/112587800/112587752/w1125h847x0y1-c8d0f1a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### High garden alpine cabin, on Santiago Sacatepequez Guatemala [](https://www.expedia.com/Santiago-Sacatepequez-Hotels-High-Garden-Alpine-Cabin.h112587752.Hotel-Information) Santiago Sacatepéquez $84 nightly $84 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Santiago-Sacatepequez-Hotels-High-Garden-Alpine-Cabin.h112587752.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/30000000/29160000/29158700/29158698/b0d7aa78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, 3 Bedrooms, Non Smoking | Private kitchen | Full-size fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/30000000/29160000/29158700/29158698/c867cad3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, 3 Bedrooms, Non Smoking | Dining room](https://images.trvl-media.com/lodging/30000000/29160000/29158700/29158698/d5522962.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29160000/29158700/29158698/3e88b292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa hermosa a 20 minutos del aeropuerto [](https://www.expedia.com/Guatemala-City-Hotels-Casa-Hermosa-A-20-Minutos-Del-Aeropuerto.h29158698.Hotel-Information) Zona 21 9.0/10 Wonderful (2 reviews) "Todo el lugar muy Bonita cómoda , limpia muy hogareña … un lugar recomendado por su comodidad muy amplia … Lo único malo q podría decir que el ruido de la construcción que había en la propiedad no fue muy buena ya que con un bb no fue cómodo … aparte que el último día no se respeto como devia de ser la hora de salida .. tuvimos que salir con prisa por que nos dijeron q a qué horas nos íbamos por que tenían que limpiar la casa …y aún no se llegaba la hora de dejar la propiedad según la... ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Ana [](https://www.expedia.com/Guatemala-City-Hotels-Casa-Hermosa-A-20-Minutos-Del-Aeropuerto.h29158698.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104450000/104443500/104443446/8765a133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds (E) | 1 bedroom, individually decorated, individually furnished, soundproofing](https://images.trvl-media.com/lodging/105000000/104450000/104443500/104443446/1ee191f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft (J5 Sencillo) | Living area | 50-inch LED TV with digital channels, Netflix, streaming services](https://images.trvl-media.com/lodging/105000000/104450000/104443500/104443446/124f22e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (R1 Triple) | Private kitchen | Full-size fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/105000000/104450000/104443500/104443446/766f9e9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cayalá Lofts [](https://www.expedia.com/Guatemala-City-Hotels-Cayala-Lofts.h104443446.Hotel-Information) Zona 16 9.0/10 Wonderful (101 reviews) "The room was small, but very clean and nice. Location was perfect. Check-in was easy and friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ingrid $99 nightly $118 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/Guatemala-City-Hotels-Cayala-Lofts.h104443446.Hotel-Information) ![Comfort Apartment, Patio | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/127000000/126150000/126141600/126141506/da17f381.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/127000000/126150000/126141600/126141506/bb5244ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/127000000/126150000/126141600/126141506/cb13c5c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/127000000/126150000/126141600/126141506/5d1e3b9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy house [](https://www.expedia.com/Antigua-Guatemala-Hotels-Cozy-House.h126141506.Hotel-Information) Barrio de La Concepción 4.0/10 (1 review) "The owner and his family were very kind and friendly. He let us keep our bags there for the day until we had to leave and gave us two separate bedrooms instead of four of us sharing one room. This is all much appreciated. The bedroom entry doors do not lock, whether you are in the room or not. Ours didn’t even latch closed. The sheets were clean for the most part but floors and walls not so much. The shared toilette and shower needs a good scrub. The other shower and bathroom we were told... ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Christine $80 nightly $98 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Antigua-Guatemala-Hotels-Cozy-House.h126141506.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/116000000/115020000/115017500/115017477/w1015h683x4y0-618a35ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/116000000/115020000/115017500/115017477/w1017h683x3y0-acc4294c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/116000000/115020000/115017500/115017477/w1016h683x4y0-4d6c8109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/116000000/115020000/115017500/115017477/w1017h683x4y0-3e9083f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Zone 10 - Central location - close to airport [](https://www.expedia.com/Guatemala-City-Hotels-Zone-10-Central-Location-Close-To-Airport.h115017477.Hotel-Information) Zona 16 10/10 Exceptional (2 reviews) "Property was in excellent condition and pictures match exactly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheily [](https://www.expedia.com/Guatemala-City-Hotels-Zone-10-Central-Location-Close-To-Airport.h115017477.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/128000000/127540000/127533600/127533524/c956b225.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127540000/127533600/127533524/fc0033f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio](https://images.trvl-media.com/lodging/128000000/127540000/127533600/127533524/f79ba714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127540000/127533600/127533524/ee227636.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Habiita13 Studio 101 [](https://www.expedia.com/Guatemala-City-Hotels-Habiita13-Studio-101.h127533524.Hotel-Information) Zona 13 $47 nightly $58 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/Guatemala-City-Hotels-Habiita13-Studio-101.h127533524.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/128000000/127540000/127533500/127533483/ff1ff130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio | Private kitchen](https://images.trvl-media.com/lodging/128000000/127540000/127533500/127533483/e7a6bab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio](https://images.trvl-media.com/lodging/128000000/127540000/127533500/127533483/96287c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127540000/127533500/127533483/28c354b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Habiita13 Studios [](https://www.expedia.com/Guatemala-City-Hotels-Habiita13-Studios.h127533483.Hotel-Information) Zona 13 $50 nightly $61 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/Guatemala-City-Hotels-Habiita13-Studios.h127533483.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/100000000/99850000/99849000/99848968/6f1c871c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/100000000/99850000/99849000/99848968/a013dd31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/100000000/99850000/99849000/99848968/9a4b9dbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/100000000/99850000/99849000/99848968/5ab541c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Big Stylish House W/jacuzzi & Lounge Pool [](https://www.expedia.com/Ciudad-Vieja-Hotels-Big-Stylish-House-Wjacuzzi-Lounge-Pool.h99848968.Hotel-Information) Ciudad Vieja $304 nightly $304 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Ciudad-Vieja-Hotels-Big-Stylish-House-Wjacuzzi-Lounge-Pool.h99848968.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/97000000/96970000/96962800/96962796/fc9e4842.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/97000000/96970000/96962800/96962796/92663f15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/97000000/96970000/96962800/96962796/b85063cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/97000000/96970000/96962800/96962796/feb5f2ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern, Cozy Apartment with Air Conditioning Encanto Cayala, Steps from Cayala [](https://www.expedia.com/Guatemala-City-Hotels-Modern.h96962796.Hotel-Information) Zona 16 10/10 Exceptional (4 reviews) "We loved the location next to Cayala and the place was clean with easy yet very secure access. Great food and shopping was was short 10 minute walk away" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) george d. $167 nightly $182 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Guatemala-City-Hotels-Modern.h96962796.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/84000000/83120000/83118700/83118669/421c845e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/84000000/83120000/83118700/83118669/845b97e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/84000000/83120000/83118700/83118669/585cc27e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83120000/83118700/83118669/122e2d57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Stays Cayala Apartments 407 [](https://www.expedia.com/Guatemala-City-Hotels-Cozy-Stays-Cayala-Apartments-407.h83118669.Hotel-Information) Zona 16 9.4/10 Exceptional (10 reviews) "Personnel were kind and helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos $120 nightly $130 total Apr 20 - Apr 21 Total with taxes and fees [](https://www.expedia.com/Guatemala-City-Hotels-Cozy-Stays-Cayala-Apartments-407.h83118669.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/115000000/114170000/114165100/114165049/5e44cf9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/115000000/114170000/114165100/114165049/2e2c2dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/115000000/114170000/114165100/114165049/ce154786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/115000000/114170000/114165100/114165049/cbd26024.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 bedroom apartment with AC in cayala, close to the US embassy [](https://www.expedia.com/Guatemala-City-Hotels-Vrbo-Property.h114165049.Hotel-Information) Zona 16 10/10 Exceptional (2 reviews) "Súper cómoda Habitaciones limpias y excelentes instalaciones " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Maria $133 nightly $145 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/Guatemala-City-Hotels-Vrbo-Property.h114165049.Hotel-Information) ![Family Apartment](https://images.trvl-media.com/lodging/128000000/127330000/127324500/127324466/94658fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/128000000/127330000/127324500/127324466/1ccc638f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment | Dining](https://images.trvl-media.com/lodging/128000000/127330000/127324500/127324466/910f1dd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment | Living area](https://images.trvl-media.com/lodging/128000000/127330000/127324500/127324466/efd0cae7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Auvé [](https://www.expedia.com/Guatemala-City-Hotels-Auve.h127324466.Hotel-Information) Zona 13 $78 nightly $96 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Guatemala-City-Hotels-Auve.h127324466.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/123000000/122190000/122189100/122189076/f7de6467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/123000000/122190000/122189100/122189076/d3296f30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122190000/122189100/122189076/27f973cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/123000000/122190000/122189100/122189076/3ad71573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful 2-bedroom home in San Pedro Las Huertas Minutes from Antigua Guatemala [](https://www.expedia.com/Antigua-Guatemala-Hotels-Beautiful-2-Bedroom-Home-In-San-Pedro-Las-Huertas-Minutes-From-Antigua-Guatemala.h122189076.Hotel-Information) San Pedro Las Huertas 10/10 Exceptional (1 review) "Great views from the roof. Super clean and nice rooms. Host was super helpful and connected! Amazing stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bayley $173 nightly $173 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Antigua-Guatemala-Hotels-Beautiful-2-Bedroom-Home-In-San-Pedro-Las-Huertas-Minutes-From-Antigua-Guatemala.h122189076.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-10&endDate=2026-04-11®ionId=3000472642&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.com/Hotel-Search?destination=Santa+Maria+de+Jesus%2C+Sacatep%C3%A9quez%2C+Guatemala®ionId=3000472642&latLong=14.492541%2C-90.708328&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=CABIN) Villas [](https://www.expedia.com/Hotel-Search?destination=Santa+Maria+de+Jesus%2C+Sacatep%C3%A9quez%2C+Guatemala®ionId=3000472642&latLong=14.492541%2C-90.708328&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=VILLA) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Santa+Maria+de+Jesus%2C+Sacatep%C3%A9quez%2C+Guatemala®ionId=3000472642&latLong=14.492541%2C-90.708328&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=APART_HOTEL) Cottages [](https://www.expedia.com/Hotel-Search?destination=Santa+Maria+de+Jesus%2C+Sacatep%C3%A9quez%2C+Guatemala®ionId=3000472642&latLong=14.492541%2C-90.708328&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=COTTAGE) Apartments [](https://www.expedia.com/Hotel-Search?destination=Santa+Maria+de+Jesus%2C+Sacatep%C3%A9quez%2C+Guatemala®ionId=3000472642&latLong=14.492541%2C-90.708328&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=APARTMENT) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Santa+Maria+de+Jesus%2C+Sacatep%C3%A9quez%2C+Guatemala®ionId=3000472642&latLong=14.492541%2C-90.708328&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=VACATION_HOME) Condos [](https://www.expedia.com/Hotel-Search?destination=Santa+Maria+de+Jesus%2C+Sacatep%C3%A9quez%2C+Guatemala®ionId=3000472642&latLong=14.492541%2C-90.708328&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=CONDO) Chalets [](https://www.expedia.com/Hotel-Search?destination=Santa+Maria+de+Jesus%2C+Sacatep%C3%A9quez%2C+Guatemala®ionId=3000472642&latLong=14.492541%2C-90.708328&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-De-Jesus-Vacation-Rentals.d3000472642.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-De-Jesus-Vacation-Rentals.d3000472642.Travel-Guide-VacationRentals) ## Top Santa Maria de Jesus Hotel Reviews ![Adriatika Hotel & Residence](https://images.trvl-media.com/lodging/9000000/8340000/8336300/8336251/9c9c2090_y.jpg) ### Adriatika Hotel & Residence 8/10 Good "The breakfast was standard fare but the staff are great!! My only complaint was the lighting in our bathroom was very bad!" [](https://expedia.com/Guatemala-City-Hotels-Adriatika-Hotel-Boutique.h8336251.Hotel-Information) ![Hotel Camino Real Antigua](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/e88ac778_y.jpg) ### Hotel Camino Real Antigua 10/10 Excellent "Amazing stay" [](https://expedia.com/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information) ![Holiday Inn Guatemala City by IHG](https://images.trvl-media.com/lodging/1000000/10000/1300/1234/fc36525d_y.jpg) ### Holiday Inn Guatemala City by IHG 8/10 Good "Breakfast was goo" [](https://expedia.com/Guatemala-City-Hotels-Holiday-Inn-Guatemala-City.h1234.Hotel-Information) ![Barceló Guatemala City](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/321f0a1f_y.jpg) ### Barceló Guatemala City 10/10 Excellent "My favorite place I like the beds View " [](https://expedia.com/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information) ![El Carmen Hotel](https://images.trvl-media.com/lodging/2000000/1220000/1211500/1211421/959d04eb_y.jpg) ### El Carmen Hotel 8/10 Good "Variety of breakfast choices and the restaurant staff was really nice." [](https://expedia.com/Antigua-Guatemala-Hotels-El-Carmen-Hotel.h1211421.Hotel-Information) ![Best Western Plus Hotel Stofella](https://images.trvl-media.com/lodging/1000000/900000/898800/898717/4d4a4357_y.jpg) ### Best Western Plus Hotel Stofella 10/10 Excellent "The breakfast options were changed almost daily, were tasty and plentiful. " [](https://expedia.com/Guatemala-City-Hotels-Best-Western-Plus-Hotel-Stofella.h898717.Hotel-Information) ![Hotel Las Americas](https://images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/861f04e5_y.jpg) ### Hotel Las Americas 10/10 Excellent "Clean rooms, great breakfast. " [](https://expedia.com/Guatemala-City-Hotels-Hotel-Las-Americas.h17403610.Hotel-Information) ![Tikal Futura Hotel & Convention Center](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/26383134_y.jpg) ### Tikal Futura Hotel & Convention Center 10/10 Excellent "Clean" [](https://expedia.com/Guatemala-City-Hotels-Grand-Tikal-Futura-Hotel.h48502.Hotel-Information) ![Hotel Museo Spa Casa Santo Domingo](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/7c0f8307_y.jpg) ### Hotel Museo Spa Casa Santo Domingo 10/10 Excellent "Really nice hotel, it’s a piece of history " [](https://expedia.com/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information) ## Find out more about Santa Maria de Jesus **Everything you need to know about Santa Maria de Jesus vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Maria de Jesus vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Maria de Jesus vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Santa Maria de Jesus vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Santa Maria de Jesus. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Maria de Jesus in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $44 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Santa Maria de Jesus rentals** At Expedia, we put the best Santa Maria de Jesus vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Santa Maria de Jesus rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Maria de Jesus vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Maria de Jesus. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in Santa Maria de Jesus ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals) - [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals) - [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals) - [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals) - [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals) - [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals) - [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals) - [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals) - [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals) - [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals) - [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals) - [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals) - [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals) - [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations) - [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations) - [Apartments in Santa Maria de Jesus ](https://expedia.com/Santa-Maria-De-Jesus-Apartments.d3000472642-aaApartments.Travel-Guide-Accommodation) - [Hostels in Santa Maria de Jesus ](https://expedia.com/Santa-Maria-De-Jesus-Hostels.d3000472642-aaHostels.Travel-Guide-Accommodation) - [Guest Houses in Santa Maria de Jesus ](https://expedia.com/Santa-Maria-De-Jesus-Guest-Houses.d3000472642-aaGuestHouses.Travel-Guide-Accommodation) - [Condo Rentals in Santa Maria de Jesus ](https://expedia.com/Santa-Maria-De-Jesus-Condos.d3000472642-aaCondos.Travel-Guide-Accommodation) - [Cabin Rentals in Santa Maria de Jesus ](https://expedia.com/Santa-Maria-De-Jesus-Cabins.d3000472642-aaCabins.Travel-Guide-Accommodation) ## Frequently asked questions ### Are there vacation rentals in Santa Maria de Jesus? ### What are some of the best vacation rentals that Santa Maria de Jesus has to offer? ### What’s there to see and do in Santa Maria de Jesus? ### What’s a vacation rental in Santa Maria de Jesus like? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app