Santa Maria de Jesus Vacation Rentals

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Our top choices for Santa Maria de Jesus vacation rentals

House in an exclusive safe and nice condo

House in an exclusive safe and nice condo
Barrio de La Concepción
10.0 out of 10, Exceptional, (1)
"We had a wonderful time visiting Guatemala. This house was perfect for our group. The host was very responsive and Dona was amazing as well. She helped clean and helped with the laundry and was so friendly. There is a nice grocery store within walking distance, the house was as described and the view was awesome. Will definitely be back. "
United States
Michelle H.
$278 nightly
The price is $278
Jan 11 - Jan 12, 2026
Total with taxes and fees
House in an exclusive safe and nice condo

Charming 3-bedroom colonial house with WiFi, fitness room in lovely Ciudad Vieja

Charming 3-bedroom colonial house with WiFi, fitness room in lovely Ciudad Vieja
Ciudad Vieja
10.0 out of 10, Exceptional, (1)
$137 nightly
The price is $137
Dec 13 - Dec 14
Total with taxes and fees
Charming 3-bedroom colonial house with WiFi, fitness room in lovely Ciudad Vieja

Casa Bella Vista Antigua guatemala/4 bed/4 blocks central park 10 P./AC,/Wiffi

Casa Bella Vista Antigua guatemala/4 bed/4 blocks central park 10 P./AC,/Wiffi
Antigua Guatemala
10.0 out of 10, Exceptional, (2)
"Beautiful and comfortable condo."
United States
Cristy C.
$546 nightly
The price is $546
Jan 4 - Jan 5, 2026
Total with taxes and fees
Casa Bella Vista Antigua guatemala/4 bed/4 blocks central park 10 P./AC,/Wiffi

Casa Piawi- Center of Antigua 4 blocks Central Park

Casa Piawi- Center of Antigua 4 blocks Central Park
Antigua Guatemala
10.0 out of 10, Exceptional, (7)
"Super clean, spacious and centrally located home. More than enough room, impeccable and well furnished! We had a wonderful stay and would request again!"
United States
Marisa C.
$243 nightly
The price is $243
Dec 16 - Dec 17
Total with taxes and fees
Casa Piawi- Center of Antigua 4 blocks Central Park

Cozy Stays Cayala Apartments 2

Cozy Stays Cayala Apartments 2
Zona 16
9.0 out of 10, Wonderful, (6)
"Great place to stay. Secure area with nice pool, gym area and views. Driving is recomended to get to the main center of town, as once you get out of the property it may not be as safe walking at night and trying to cross the very busy road."
United States
Daniel
$126 nightly
The price is $136
Dec 14 - Dec 15
Total with taxes and fees
Cozy Stays Cayala Apartments 2

Cozy Stays Cayala Apartments 407

Cozy Stays Cayala Apartments 407
Zona 16
9.6 out of 10, Exceptional, (8)
"The only thing that I didn’t like was that the floor was dirt but overall was good place and area was great. "
United States
Luis
$112 nightly
The price is $121
Dec 15 - Dec 16
Total with taxes and fees
Cozy Stays Cayala Apartments 407

Zone 10 - Central location - close to airport

Zone 10 - Central location - close to airport
Zona 16
10.0 out of 10, Exceptional, (2)
"Property was in excellent condition and pictures match exactly "
United States
Sheily
$80 nightly
The price is $80
Dec 15 - Dec 16
Total with taxes and fees
Zone 10 - Central location - close to airport

Hermoso Apartamento Vista Hermosa 2, Zona 15, a 5 Minutos de Cayalá

Hermoso Apartamento Vista Hermosa 2, Zona 15, a 5 Minutos de Cayalá
Zona 15
10.0 out of 10, Exceptional, (1)
"Excelent"
Mexico
Ana
$109 nightly
The price is $109
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hermoso Apartamento Vista Hermosa 2, Zona 15, a 5 Minutos de Cayalá

Airport view, luxury and central location.

Airport view, luxury and central location.
Zona 13
10.0 out of 10, Exceptional, (2)
"It was clean and nice Super close to airport"
United States
Jose G.
$155 nightly
The price is $155
Dec 22 - Dec 23
Total with taxes and fees
Airport view, luxury and central location.

“Casa Amelia” gorgeous Antigua Guatemala, reduced prices due to a cancellation

“Casa Amelia” gorgeous Antigua Guatemala, reduced prices due to a cancellation
Historic Center
9.4 out of 10, Exceptional, (30)
"Very cozy home! We enjoyed our stay "
Canada
Julia d.
$320 nightly
The price is $320
Dec 15 - Dec 16
Total with taxes and fees
“Casa Amelia” gorgeous Antigua Guatemala, reduced prices due to a cancellation

6 bedroom Home in Antigua Guatemala- Next to Iglesia Merced

6 bedroom Home in Antigua Guatemala- Next to Iglesia Merced
Historic Center
8.6 out of 10, Excellent, (4)
"It was a great location, it was clean. 2 showers did not have hot water, the rest did. "
United States
Ana G.
$391 nightly
The price is $391
Dec 14 - Dec 15
Total with taxes and fees
6 bedroom Home in Antigua Guatemala- Next to Iglesia Merced

Family friendly house in gated community

Family friendly house in gated community
Antigua Guatemala
9.4 out of 10, Exceptional, (3)
"Beautiful house in a beautiful gated community. We greatly enjoyed our stay. The house is very well kept and a pleasure to spend time in. The host was very responsive and accommodating. Thank you!"
United States
Andrew B.
$172 nightly
The price is $172
Dec 15 - Dec 16
Total with taxes and fees
Family friendly house in gated community

A jewel of a home ten minutes away from Antigua

A jewel of a home ten minutes away from Antigua
Jocotenango
9.0 out of 10, Wonderful, (2)
"El orden y la limpieza de la casa en general "
Mexico
Reyna
$183 nightly
The price is $189
Dec 15 - Dec 16
Total with taxes and fees
A jewel of a home ten minutes away from Antigua

Pink House 604

Pink House 604
3.0 star property
Zona 16
8.0 out of 10, Very Good, (2)
"Clean "
United States
Rosa
$98 nightly
The price is $119
Dec 15 - Dec 16
Total with taxes and fees
Pink House 604

L AURORA INN Apart

L AURORA INN Apart
4.0 star property
Zona 13
10.0 out of 10, Exceptional, (2)
"El apartamento superó mis expectativas, las habitaciones muy cómodas y limpias, el personal amable y servicial, el desayuno estuvo muy bueno. Quedamos muy satisfechos "
Mexico
Damaris
$92 nightly
The price is $113
Dec 13 - Dec 14
Total with taxes and fees
L AURORA INN Apart

2 bedroom apartment with AC in cayala, close to the US embassy

2 bedroom apartment with AC in cayala, close to the US embassy
Zona 16
10.0 out of 10, Exceptional, (1)
"Súper cómoda Habitaciones limpias y excelentes instalaciones "
Mexico
Maria
$133 nightly
The price is $145
Dec 15 - Dec 16
Total with taxes and fees
2 bedroom apartment with AC in cayala, close to the US embassy

a 5 minutos del aeropuerto, zoologico y museos de antropologia e historia

a 5 minutos del aeropuerto, zoologico y museos de antropologia e historia
Zona 13
10.0 out of 10, Exceptional, (2)
"We stayed for 8 days. The location was excellent. We felt very safe. The security in the building was awesome. Would definitely recommend this oroperty"
Canada
Georgina H.
$113 nightly
The price is $113
Dec 14 - Dec 15
Total with taxes and fees
a 5 minutos del aeropuerto, zoologico y museos de antropologia e historia

Luxurious, modern and central (Z10)

Luxurious, modern and central (Z10)
Zona 10
10.0 out of 10, Exceptional, (4)
"It was a perfect place for me and my friends, very clean and the location is perfect. Close to stores and other places we wanted to visit. San Martin restaurant down the street was awesome! Parking is perfect as well. This is the second time I stay at this place and it’s perfect for what we were looking for. "
United States
Roberto A.
$138 nightly
The price is $138
Dec 24 - Dec 25
Total with taxes and fees
Luxurious, modern and central (Z10)

Luxury Private Coffee Estate in Antigua Guatemala for Large Groups and Families

Luxury Private Coffee Estate in Antigua Guatemala for Large Groups and Families
Antigua Guatemala
10.0 out of 10, Exceptional, (2)
"Had a fabulous birthday celebration with family and friends at Finca San Mateo. Juan Carlos, the owner went above and beyond to help us have a great time during our stay. The house was very clean and my family and friends enjoyed the breakfast and coffee every morning. My only side note if you are a light sleeper this property is near a busy road and the roosters and dogs can be very loud. Other than that I highly recommend Finca San Mateo. "
United States
Susana P.
$606 nightly
The price is $606
Dec 16 - Dec 17
Total with taxes and fees
Luxury Private Coffee Estate in Antigua Guatemala for Large Groups and Families

Cozy Stays Cayala Apartments 5

Cozy Stays Cayala Apartments 5
Zona 16
9.4 out of 10, Exceptional, (8)
"This is the second time we used Mercela’s properties and both time have been excellent, from reservation to check out, we will use it again"
United States
Anonymous traveler
$112 nightly
The price is $121
Dec 15 - Dec 16
Total with taxes and fees
Cozy Stays Cayala Apartments 5
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Maria de Jesus Hotel Reviews

Find out more about Santa Maria de Jesus

Everything you need to know about Santa Maria de Jesus vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Maria de Jesus vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Maria de Jesus vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Maria de Jesus vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Maria de Jesus. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Maria de Jesus in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $29 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Maria de Jesus rentals

At Expedia, we put the best Santa Maria de Jesus vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Maria de Jesus rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Maria de Jesus vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Maria de Jesus. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santa Maria de Jesus?

Yes, there are vacation rentals near popular sights in Santa Maria de Jesus, or you can go with a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals that Santa Maria de Jesus has to offer?

Spacious 4-bedroom townhome in peaceful San Pedro Las Huertas with WiFi: This vacation home rental outside of Santa Maria de Jesus has laundry facilities and WiFi to help you feel perfectly comfortable in your new surroundings.

What’s there to see and do in Santa Maria de Jesus?

Explore the area and family-friendly sights such as Mundo Petapa, or get out into nature at a spot like Volcan de Agua. In the larger area, you’ll find Cortijo de Las Flores and San Jose el Viejo Ruins.

What’s a vacation rental in Santa Maria de Jesus like?

Vacation rentals are privately owned properties you can book for a long or short time in Santa Maria de Jesus. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so you'll have a home away from home. If you're concerned about a clean environment, a vacation rental can offer a sense of seclusion away from shared hotel elevators and busy front desks while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a family getaway.