Santa María

Travel Guide

Gran Melia Iguazú

Gran Melia Iguazú

5 out of 5
Parque Nacional Iguazu Puerto Iguazú Misiones
$743 nightly
The price is $752 total per night from Dec 6 to Dec 7
$752 total
Dec 6 - Dec 7
Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,000 reviews)
"Everything was great. Specially feeling like being in middle of wilderness"

Reviewed on Nov 5, 2026

Gran Melia Iguazú
Hotel Saint George

Hotel Saint George

4 out of 5
Avenida Cordoba 148 Puerto Iguazú Misiones
$121 nightly
The price is $127 total per night from Nov 10 to Nov 11
$127 total
Nov 10 - Nov 11
Book a stay at this spa hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Hotel Saint George
Loi Suites Iguazú Hotel

Loi Suites Iguazú Hotel

5 out of 5
Selva Iriapu Sin Numero Puerto Iguazú Misiones
$337 nightly
The price is $346 total per night from Nov 16 to Nov 17
$346 total
Nov 16 - Nov 17
Book a stay at this luxury resort in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our ...
9.2/10 Wonderful! (1,000 reviews)
"The place is nice enough. Unless you are an infant, you'll probably die of old age waiting for your food or drink orders to be filled. Breakfasts are good. The breakfast food quality is acceptable and it's buffet style, so you don't have to wait on the server to bring you the food. If you want a ..."

Reviewed on Oct 30, 2026

Loi Suites Iguazú Hotel
See all 404 properties in Misiones Province
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Marín Apartments

Marín Apartments

3 out of 5
Av. San Martín 77 Puerto Iguazú Misiones
Stay at this apartment in Puerto Iguazú. Enjoy free WiFi, cable TV channels, and an in-room coffeemaker. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (92 reviews)
"It’s a good value for the money that take care of any problems pretty much right away the very attentive. It’s an a quiet place plenty of room more room than you can imagine. I would recommend it for anybody that wants to get away from the city and have a place that’s close to the Falls."

Reviewed on Nov 1, 2026

Marín Apartments
Reserva Natural Iguazú - Pristine Luxury Camp

Reserva Natural Iguazú - Pristine Luxury Camp

3.5 out of 5
Colectora Calle 17 de Octubre Puerto Libertad Misiones
Book a stay at this business-friendly hotel in Puerto Libertad. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Guarani Mythological Park ...
9/10 Wonderful! (7 reviews)
"When we got to this property, we were very excited. It was beautifully located in the jungle and the rooms are individual huts. Very remote, very beautiful. We were pretty quickly surprised by the staff. Very few were helpful. We believe it’s because we don’t speak much Spanish, but we tried our ..."

Reviewed on Oct 6, 2026

Reserva Natural Iguazú - Pristine Luxury Camp
Departamento para 8 personas

Departamento para 8 personas

Puerto Iguazú Misiones
Stay at this apartment in Puerto Iguazú. Enjoy patios and air conditioning. Popular attractions Three Borders Landmark and Cataratas Avenue are located ...
10/10 Exceptional! (1 review)
"Helpful and great communication!"

Reviewed on Feb 8, 2026

Departamento para 8 personas
See all 404 properties in Misiones Province
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What cuisines can you find in Santa María?
In Santa María, you can find South American cuisine, featuring popular dishes like empanadas, ceviche, and grilled meats. Travelers can also enjoy Latin American, Asian, and North American options, alongside fresh seafood dishes such as grilled fish, and a selection of coffee shops.
Can I book a refundable hotel in Santa María?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Santa María by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Santa María with Expedia?
Expedia makes it easier to plan your Santa María trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Santa María?
The best choice depends on your travel style. Hotels in Santa María can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Santa María trip on Expedia?
Once you've booked your Santa María trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Santa María trip?
Expedia offers customer support before, during, and after your Santa María trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Santa María?
If it's your first trip to Santa María, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Santa María hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Santa María hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.