Title: The Best Non-Smoking Hotels in Santa Rosa, NM from $78 in 2026 | Expedia.com [Santa Rosa Travel Guide](https://expedia.com/Santa-Rosa.dx7957)[Hotels in Santa Rosa](https://expedia.com/Santa-Rosa-Hotels.d7957.Travel-Guide-Hotels)[Vacation Rentals in Santa Rosa](https://expedia.com/Santa-Rosa-Vacation-Rentals.d7957.Travel-Guide-VacationRentals)[Flights to Santa Rosa](https://expedia.com/Cheap-Flights-To-Santa-Rosa.d7957.Travel-Guide-Flights)[Car Rentals in Santa Rosa](https://expedia.com/Car-Rentals-In-Santa-Rosa.d7957.Car-Rental-Guide)[Santa Rosa Vacation Packages](https://expedia.com/Santa-Rosa.d7957.Destination-Travel-Guides) ![Adobe](https://images.trvl-media.com/place/7957/e965856e-3bf4-4e4d-9d01-a3fe3c3727d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/7957/e965856e-3bf4-4e4d-9d01-a3fe3c3727d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check availability on Santa Rosa Non-Smoking Hotels Tonight [Apr 6 - Apr 7](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-04-06&endDate=2026-04-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 7 - Apr 8](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-04-07&endDate=2026-04-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Rosa non-smoking hotels ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/b37d4531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/2f33cca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking (Limited View) | Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/5f184cea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 2 Queen Beds, Non Smoking (Limited View) | Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/22ae7aed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Santa Rosa [](https://www.expedia.com/Santa-Rosa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Rosa.h63219.Hotel-Information) Santa Rosa 9.2/10 Wonderful (1,473 reviews) "Courteous staff, clean rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) PATRICK $130 nightly $147 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Rosa.h63219.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/b1fd168f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible, Non Smoking (Pet Friendly) | Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/19202927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/8f3f0364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/c85e1c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Blue 66, BW Signature Collection [](https://www.expedia.com/Santa-Rosa-Hotels-Hotel-Blue-66.h43173.Hotel-Information) Santa Rosa 8.6/10 Excellent (260 reviews) "Would stay again.." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sherrie $85 nightly $96 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Hotel-Blue-66.h43173.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/c11e5c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/f3d0564e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/96e5b26a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/0e59560e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santa Rosa [](https://www.expedia.com/Santa-Rosa-Hotels-Super-8-By-Wyndham-Santa-Rosa.h42144.Hotel-Information) Santa Rosa 7.8/10 Good (1,004 reviews) "Clean pet friendly convenient online last min off the road stay for traveling " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lakiesha $71 nightly $80 total Apr 21 - Apr 22 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Super-8-By-Wyndham-Santa-Rosa.h42144.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/1cd3aecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/3e320fd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/daeff167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/827a2643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Santa Rosa on Route 66 [](https://www.expedia.com/Santa-Rosa-Hotels-Comfort-Inn-City-Of-Natural-Lakes.h3029935.Hotel-Information) Santa Rosa 8.4/10 Very Good (1,005 reviews) "Stayed here during spring break and i have to say this is the best hotel we stayed at. Breakfast was delicious and staff was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carla $101 nightly $115 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Comfort-Inn-City-Of-Natural-Lakes.h3029935.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/232e579e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/6710dd6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/f81361a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/4de52e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express SANTA ROSA by IHG [](https://www.expedia.com/Santa-Rosa-Hotels-Holiday-Inn-Express-SANTA-ROSA.h61515.Hotel-Information) Santa Rosa 8.4/10 Very Good (1,000 reviews) "Room was clean and very roomy!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Francisco $127 nightly $144 total May 7 - May 8 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Holiday-Inn-Express-SANTA-ROSA.h61515.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/0b60c804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/24876991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/aaec3894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/a14416cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Inn & Suites Santa Rosa [](https://www.expedia.com/Santa-Rosa-Hotels-Econo-Lodge.h79553.Hotel-Information) Santa Rosa 8.6/10 Excellent (1,004 reviews) "Clean, affordable and good for a quick stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory $85 nightly $96 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Econo-Lodge.h79553.Hotel-Information) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3840x5y0-80c91fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3840x5y0-7f714321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3835x5y5-5c0a3c1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3840x5y0-0cf331bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Santa Rosa Inn [](https://www.expedia.com/Santa-Rosa-Hotels-Best-Western-Santa-Rosa-Inn.h740.Hotel-Information) Santa Rosa 9.2/10 Wonderful (1,002 reviews) "Nice place for a small town. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matt $128 nightly $145 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Best-Western-Santa-Rosa-Inn.h740.Hotel-Information) ![Free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/29ab67ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/20dfdf75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/b734ef2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/31f98f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Santa Rosa, NM [](https://www.expedia.com/Santa-Rosa-Hotels-Motel-6-Santa-Rosa.h996304.Hotel-Information) Santa Rosa 6.6/10 (1,001 reviews) "Easy parking " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Esther $69 nightly $78 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Motel-6-Santa-Rosa.h996304.Hotel-Information) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/8e633060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/0065afd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/489109af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/087bfcf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Vaughn [](https://www.expedia.com/Vaughn-Hotels-Travelodge-By-Wyndham-Vaughn.h216446.Hotel-Information) Vaughn 6.2/10 (227 reviews) "The room was clean and comfortable. Loved the Penny’s Diner. The waiter was very friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $93 nightly $106 total Apr 25 - Apr 26 Total with taxes and fees [](https://www.expedia.com/Vaughn-Hotels-Travelodge-By-Wyndham-Vaughn.h216446.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-21&endDate=2026-04-22®ionId=7957&adults=2&property_amenities_group_explore=smokefree_property&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Rosa Hotel Reviews ![Hampton Inn Santa Rosa](https://images.trvl-media.com/lodging/2000000/1810000/1802500/1802485/28421f88_y.jpg) ### Hampton Inn Santa Rosa 4/10 Poor "Had dogs behind hotel barking all night Not good for sleeping " [](https://expedia.com/Santa-Rosa-Hotels-Hampton-Inn-Santa-Rosa.h1802485.Hotel-Information) ![Days Inn & Suites by Wyndham Santa Rosa](https://images.trvl-media.com/lodging/1000000/30000/26300/26232/2fbf722e_y.jpg) ### Days Inn & Suites by Wyndham Santa Rosa 8/10 Good "Breakfast was really good, the location was convenient, and the room was fine, though it did have a slightly musty odor at first. We opened the windows and that seemed to help. This particular hotel has rooms that open to the outside, but other than that, this was a good place to stay." [](https://expedia.com/Santa-Rosa-Hotels-Days-Inn-Suites-By-Wyndham-Santa-Rosa.h26232.Hotel-Information) ![Americas Best Value Inn Santa Rosa, NM](https://images.trvl-media.com/lodging/6000000/5410000/5406600/5406552/0881e626_y.jpg) ### Americas Best Value Inn Santa Rosa, NM 4/10 Poor "Overall I would rate this hotel as poor to okay The rooms were not very clean and the beds not really very comfortable. The bathroom was not clean, especially in the corners. And it appeared that they put in a new toilet. However, the seat was loose. no carts for luggage. No counter space in the bathroom. The breakfast consisted of cold cereal and a denish ., milk juice and coffee." [](https://expedia.com/Santa-Rosa-Hotels-Americas-Best-Value-Inn-Santa-Rosa.h5406552.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Santa Rosa](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/b37d4531_y.jpg) ### La Quinta Inn & Suites by Wyndham Santa Rosa 10/10 Excellent "Very clean and comfortable. Staff was great. Nicest Laquinta in a long time. " [](https://expedia.com/Santa-Rosa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Rosa.h63219.Hotel-Information) ![Holiday Inn Express SANTA ROSA by IHG](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/232e579e_y.jpg) ### Holiday Inn Express SANTA ROSA by IHG 8/10 Good "Breakfast was good" [](https://expedia.com/Santa-Rosa-Hotels-Holiday-Inn-Express-SANTA-ROSA.h61515.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near St. Rose of Lima Catholic Church ](https://www.expedia.com/St-Rose-Of-Lima-Catholic-Church-Hotels.0-l6239810-0.Travel-Guide-Filter-Hotels) - [Hotels near Blue Hole ](https://www.expedia.com/Blue-Hole-Hotels.0-l6239808-0.Travel-Guide-Filter-Hotels) - [Hotels near Route 66 Auto Museum ](https://www.expedia.com/Route-66-Auto-Museum-Hotels.0-l6239813-0.Travel-Guide-Filter-Hotels) - [Cuervo Hotels ](https://www.expedia.com/Cuervo-Hotels.d553248635974903048.Travel-Guide-Hotels) - [Newkirk Hotels ](https://www.expedia.com/Newkirk-Hotels.d553248635974902968.Travel-Guide-Hotels) - 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