Title: The Best Non-Smoking Hotels in Santa Rosa, NM from $78 in 2026 | Expedia.com [Santa Rosa Travel Guide](https://expedia.com/Santa-Rosa.dx7957)[Hotels in Santa Rosa](https://expedia.com/Santa-Rosa-Hotels.d7957.Travel-Guide-Hotels)[Vacation Rentals in Santa Rosa](https://expedia.com/Santa-Rosa-Vacation-Rentals.d7957.Travel-Guide-VacationRentals)[Flights to Santa Rosa](https://expedia.com/Cheap-Flights-To-Santa-Rosa.d7957.Travel-Guide-Flights)[Car Rentals in Santa Rosa](https://expedia.com/Car-Rentals-In-Santa-Rosa.d7957.Car-Rental-Guide)[Santa Rosa Vacation Packages](https://expedia.com/Santa-Rosa.d7957.Destination-Travel-Guides) ![Adobe](https://images.trvl-media.com/place/7957/e965856e-3bf4-4e4d-9d01-a3fe3c3727d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/7957/e965856e-3bf4-4e4d-9d01-a3fe3c3727d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check availability on Santa Rosa Non-Smoking Hotels Tonight [Mar 23 - Mar 24](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-03-23&endDate=2026-03-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 24 - Mar 25](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-03-24&endDate=2026-03-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Rosa non-smoking hotels ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/b37d4531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking (Limited View) | Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/5f184cea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/65f91b34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/2f33cca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Santa Rosa [](https://www.expedia.com/Santa-Rosa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Rosa.h63219.Hotel-Information) Santa Rosa 9.2/10 Wonderful (1,474 reviews) "Courteous staff, clean rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) PATRICK $130 nightly $147 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Rosa.h63219.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/0b60c804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/24876991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/a14416cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/aaec3894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Inn & Suites Santa Rosa [](https://www.expedia.com/Santa-Rosa-Hotels-Econo-Lodge.h79553.Hotel-Information) Santa Rosa 8.6/10 Excellent (1,004 reviews) "Clean, affordable and good for a quick stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory $80 nightly $91 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Econo-Lodge.h79553.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/c11e5c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/0e59560e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/5854844a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/96e5b26a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santa Rosa [](https://www.expedia.com/Santa-Rosa-Hotels-Super-8-By-Wyndham-Santa-Rosa.h42144.Hotel-Information) Santa Rosa 7.8/10 Good (1,002 reviews) "Clean pet friendly convenient online last min off the road stay for traveling " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lakiesha $71 nightly $81 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Super-8-By-Wyndham-Santa-Rosa.h42144.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/1cd3aecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/827a2643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/daeff167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/3e320fd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Santa Rosa on Route 66 [](https://www.expedia.com/Santa-Rosa-Hotels-Comfort-Inn-City-Of-Natural-Lakes.h3029935.Hotel-Information) Santa Rosa 8.4/10 Very Good (1,008 reviews) "Stayed here during spring break and i have to say this is the best hotel we stayed at. Breakfast was delicious and staff was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carla $101 nightly $115 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Comfort-Inn-City-Of-Natural-Lakes.h3029935.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/232e579e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/4de52e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/f81361a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/6710dd6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express SANTA ROSA by IHG [](https://www.expedia.com/Santa-Rosa-Hotels-Holiday-Inn-Express-SANTA-ROSA.h61515.Hotel-Information) Santa Rosa 8.4/10 Very Good (1,002 reviews) "Room was clean and very roomy!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Francisco $142 nightly $161 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Holiday-Inn-Express-SANTA-ROSA.h61515.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/b1fd168f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible, Non Smoking (Pet Friendly) | Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/19202927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/8f3f0364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/d95d3571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Blue 66, BW Signature Collection [](https://www.expedia.com/Santa-Rosa-Hotels-Hotel-Blue-66.h43173.Hotel-Information) Santa Rosa 8.4/10 Very Good (244 reviews) "Would stay again.." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sherrie $100 nightly $113 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Hotel-Blue-66.h43173.Hotel-Information) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3840x5y0-80c91fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3840x5y0-7f714321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3840x5y0-0cf331bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5757h3835x3y5-26f998db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Santa Rosa Inn [](https://www.expedia.com/Santa-Rosa-Hotels-Best-Western-Santa-Rosa-Inn.h740.Hotel-Information) Santa Rosa 9.2/10 Wonderful (1,006 reviews) "Nice place for a small town. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matt $141 nightly $160 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Best-Western-Santa-Rosa-Inn.h740.Hotel-Information) ![Free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/29ab67ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/20dfdf75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/b734ef2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/31f98f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Santa Rosa, NM [](https://www.expedia.com/Santa-Rosa-Hotels-Motel-6-Santa-Rosa.h996304.Hotel-Information) Santa Rosa 6.6/10 (1,002 reviews) "Quick check in. Slept well. Bedding was clean and comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher $69 nightly $78 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Motel-6-Santa-Rosa.h996304.Hotel-Information) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/8e633060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/0065afd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/489109af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/087bfcf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Vaughn [](https://www.expedia.com/Vaughn-Hotels-Travelodge-By-Wyndham-Vaughn.h216446.Hotel-Information) Vaughn 6.2/10 (227 reviews) "The room was clean and comfortable. Loved the Penny’s Diner. The waiter was very friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $85 nightly $96 total Apr 10 - Apr 11 Total with taxes and fees [](https://www.expedia.com/Vaughn-Hotels-Travelodge-By-Wyndham-Vaughn.h216446.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08®ionId=7957&adults=2&property_amenities_group_explore=smokefree_property&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Rosa Hotel Reviews ![La Quinta Inn & Suites by Wyndham Santa Rosa](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/b37d4531_y.jpg) ### La Quinta Inn & Suites by Wyndham Santa Rosa 10/10 Excellent "Great property. We thought the pet area was really nice. We were helped by Mike Salazar and he was super helpful and friendly. The king suite is really large and very nice. The property was renovated a couple of years ago and is really set up well." [](https://expedia.com/Santa-Rosa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Rosa.h63219.Hotel-Information) ![Hampton Inn Santa Rosa](https://images.trvl-media.com/lodging/2000000/1810000/1802500/1802485/28421f88_y.jpg) ### Hampton Inn Santa Rosa 10/10 Excellent "My grandsons really enjoyed the swimming pool & the game room. It was very comfortable." [](https://expedia.com/Santa-Rosa-Hotels-Hampton-Inn-Santa-Rosa.h1802485.Hotel-Information) ![Days Inn & Suites by Wyndham Santa Rosa](https://images.trvl-media.com/lodging/1000000/30000/26300/26232/2fbf722e_y.jpg) ### Days Inn & Suites by Wyndham Santa Rosa 6/10 Okay "Soap dispensers in room were empty. " [](https://expedia.com/Santa-Rosa-Hotels-Days-Inn-Suites-By-Wyndham-Santa-Rosa.h26232.Hotel-Information) ![Holiday Inn Express SANTA ROSA by IHG](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/232e579e_y.jpg) ### Holiday Inn Express SANTA ROSA by IHG 10/10 Excellent "Did not use. Room very nice, clean. Excellent staff interaction. Nice hot breakfast." [](https://expedia.com/Santa-Rosa-Hotels-Holiday-Inn-Express-SANTA-ROSA.h61515.Hotel-Information) ![Americas Best Value Inn Santa Rosa, NM](https://images.trvl-media.com/lodging/6000000/5410000/5406600/5406552/0881e626_y.jpg) ### Americas Best Value Inn Santa Rosa, NM 6/10 Okay "Facilities old, cleaniless okay. Breakfast limited to waffle and cereals and sweet rolls. Few apples and juices" [](https://expedia.com/Santa-Rosa-Hotels-Americas-Best-Value-Inn-Santa-Rosa.h5406552.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near St. Rose of Lima Catholic Church ](https://www.expedia.com/St-Rose-Of-Lima-Catholic-Church-Hotels.0-l6239810-0.Travel-Guide-Filter-Hotels) - [Hotels near Blue Hole ](https://www.expedia.com/Blue-Hole-Hotels.0-l6239808-0.Travel-Guide-Filter-Hotels) - [Hotels near Route 66 Auto Museum ](https://www.expedia.com/Route-66-Auto-Museum-Hotels.0-l6239813-0.Travel-Guide-Filter-Hotels) - [Cuervo Hotels ](https://www.expedia.com/Cuervo-Hotels.d553248635974903048.Travel-Guide-Hotels) - [Newkirk Hotels ](https://www.expedia.com/Newkirk-Hotels.d553248635974902968.Travel-Guide-Hotels) - [Pet-Friendly Hotels in Vaughn ](https://www.expedia.com/Vaughn-Hotels-Pet-Friendly-Hotel.0-0-d56019-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Gym in Vaughn ](https://www.expedia.com/Vaughn-Hotels-Hotels-With-Fitness-Center.0-0-d56019-tHotelswithFitnessCenter.Travel-Guide-Filter-Hotels) - 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