Title: The Best Non-Smoking Hotels in Santa Rosa from $78 in 2026 | Expedia.com [Santa Rosa Travel Guide](https://expedia.com/Santa-Rosa.dx7957)[Hotels in Santa Rosa](https://expedia.com/Santa-Rosa-Hotels.d7957.Travel-Guide-Hotels)[Vacation Rentals in Santa Rosa](https://expedia.com/Santa-Rosa-Vacation-Rentals.d7957.Travel-Guide-VacationRentals)[Flights to Santa Rosa](https://expedia.com/Cheap-Flights-To-Santa-Rosa.d7957.Travel-Guide-Flights)[Car Rentals in Santa Rosa](https://expedia.com/Car-Rentals-In-Santa-Rosa.d7957.Car-Rental-Guide)[Santa Rosa Vacation Packages](https://expedia.com/Santa-Rosa.d7957.Destination-Travel-Guides) ![Adobe](https://images.trvl-media.com/place/7957/e965856e-3bf4-4e4d-9d01-a3fe3c3727d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/7957/e965856e-3bf4-4e4d-9d01-a3fe3c3727d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Rosa Non-Smoking Hotels Tonight [Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 7 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=7957&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Rosa non-smoking hotels ![Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/c11e5c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/5854844a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/f3d0564e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/50000/42200/42144/0e59560e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santa Rosa [](https://www.expedia.com/Santa-Rosa-Hotels-Super-8-By-Wyndham-Santa-Rosa.h42144.Hotel-Information) Santa Rosa 7.8/10 Good (1,005 reviews) "the room was clean and well maintained. It was a good value." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $73 nightly $83 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Super-8-By-Wyndham-Santa-Rosa.h42144.Hotel-Information) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/b37d4531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/65f91b34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking (Limited View) | Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/5f184cea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/2f33cca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Santa Rosa [](https://www.expedia.com/Santa-Rosa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Rosa.h63219.Hotel-Information) Santa Rosa 9.2/10 Wonderful (1,462 reviews) "Clean room, nice staff, good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle $144 nightly $163 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Rosa.h63219.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/0b60c804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/a14416cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/aaec3894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/80000/79600/79553/24876991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Inn & Suites Santa Rosa [](https://www.expedia.com/Santa-Rosa-Hotels-Econo-Lodge.h79553.Hotel-Information) Santa Rosa 8.6/10 Excellent (1,006 reviews) "Nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle $80 nightly $91 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Econo-Lodge.h79553.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/1cd3aecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/031bfe4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/827a2643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3030000/3030000/3029935/daeff167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Santa Rosa on Route 66 [](https://www.expedia.com/Santa-Rosa-Hotels-Comfort-Inn-City-Of-Natural-Lakes.h3029935.Hotel-Information) Santa Rosa 8.4/10 Very Good (1,001 reviews) "Very clean and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) shannell $105 nightly $119 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Comfort-Inn-City-Of-Natural-Lakes.h3029935.Hotel-Information) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3840x5y0-80c91fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3840x5y0-7f714321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3840x5y0-0cf331bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/740/w5755h3835x5y5-5c0a3c1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Santa Rosa Inn [](https://www.expedia.com/Santa-Rosa-Hotels-Best-Western-Santa-Rosa-Inn.h740.Hotel-Information) Santa Rosa 9.2/10 Wonderful (1,004 reviews) "Was passing through for one night. Clean, renovated, quiet rooms and comfortable beds. Would stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah $114 nightly $130 total Feb 13 - Feb 14 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Best-Western-Santa-Rosa-Inn.h740.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/232e579e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/6710dd6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/af59b708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/4de52e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express SANTA ROSA by IHG [](https://www.expedia.com/Santa-Rosa-Hotels-Holiday-Inn-Express-SANTA-ROSA.h61515.Hotel-Information) Santa Rosa 8.4/10 Very Good (1,001 reviews) "The parking was enough for my large u-haul truck and the breakfast had all the options my kids needed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ryan $142 nightly $161 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Holiday-Inn-Express-SANTA-ROSA.h61515.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/b1fd168f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/c85e1c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible, Non Smoking (Pet Friendly) | Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/19202927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/43200/43173/d95d3571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Blue 66, BW Signature Collection [](https://www.expedia.com/Santa-Rosa-Hotels-Hotel-Blue-66.h43173.Hotel-Information) Santa Rosa 8.4/10 Very Good (205 reviews) "Clean room, great breakfast, staff- great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Foram $85 nightly $96 total Feb 13 - Feb 14 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Hotel-Blue-66.h43173.Hotel-Information) ![Free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/29ab67ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/b734ef2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/31f98f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996400/996304/20dfdf75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Santa Rosa, NM [](https://www.expedia.com/Santa-Rosa-Hotels-Motel-6-Santa-Rosa.h996304.Hotel-Information) Santa Rosa 6.6/10 (1,001 reviews) "Room was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily $69 nightly $78 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Santa-Rosa-Hotels-Motel-6-Santa-Rosa.h996304.Hotel-Information) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/8e633060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/27caa186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/087bfcf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/216500/216446/489109af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Vaughn [](https://www.expedia.com/Vaughn-Hotels-Travelodge-By-Wyndham-Vaughn.h216446.Hotel-Information) Vaughn 6.2/10 (223 reviews) "The room was clean and comfortable. Loved the Penny’s Diner. The waiter was very friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $98 nightly $111 total Mar 7 - Mar 8 Total with taxes and fees [](https://www.expedia.com/Vaughn-Hotels-Travelodge-By-Wyndham-Vaughn.h216446.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22®ionId=7957&adults=2&property_amenities_group_explore=smokefree_property&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Rosa Hotel Reviews ![La Quinta Inn & Suites by Wyndham Santa Rosa](https://images.trvl-media.com/lodging/1000000/70000/63300/63219/b37d4531_y.jpg) ### La Quinta Inn & Suites by Wyndham Santa Rosa 10/10 Excellent "Rooms clean, friendly desk clerk " [](https://expedia.com/Santa-Rosa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Rosa.h63219.Hotel-Information) ![Days Inn & Suites by Wyndham Santa Rosa](https://images.trvl-media.com/lodging/1000000/30000/26300/26232/fb84d4ee_y.jpg) ### Days Inn & Suites by Wyndham Santa Rosa 10/10 Excellent "Really nice staff " [](https://expedia.com/Santa-Rosa-Hotels-Days-Inn-Suites-By-Wyndham-Santa-Rosa.h26232.Hotel-Information) ![Americas Best Value Inn Santa Rosa, NM](https://images.trvl-media.com/lodging/6000000/5410000/5406600/5406552/1b0f37e1_y.jpg) ### Americas Best Value Inn Santa Rosa, NM 10/10 Excellent "The room was very simple, charming and comfortable. I was happy with it. " [](https://expedia.com/Santa-Rosa-Hotels-Americas-Best-Value-Inn-Santa-Rosa.h5406552.Hotel-Information) ![Holiday Inn Express SANTA ROSA by IHG](https://images.trvl-media.com/lodging/1000000/70000/61600/61515/7f3603d1_y.jpg) ### Holiday Inn Express SANTA ROSA by IHG 10/10 Excellent "The parking was enough for my large u-haul truck and the breakfast had all the options my kids needed." [](https://expedia.com/Santa-Rosa-Hotels-Holiday-Inn-Express-SANTA-ROSA.h61515.Hotel-Information) ![Hampton Inn Santa Rosa](https://images.trvl-media.com/lodging/2000000/1810000/1802500/1802485/865b0c22_y.jpg) ### Hampton Inn Santa Rosa 10/10 Excellent "Hotel was a little "tired" - i.e. needed some sprucing up." 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