Santo Domingo Vacations from $427

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The Latest Santo Domingo vacation packages

Price found within the past 48 hours. Click for updated prices.
Tau House

Tau House

3 out of 5
Save 100% on your flight
Price was $815, price is now $427 per person
$427
per person
Nov 5 - Nov 9
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Medellín (MDE)
9.4/10 Exceptional! (100 reviews)
The views are excellent

Reviewed on Sep 27, 2025

EP Casa Uribe Architecture Art & Nature

EP Casa Uribe Architecture Art & Nature

4 out of 5
El Poblado
Price was $3,070, price is now $1,356 per person
$1,356
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip flight included
Miami (MIA) to Medellín (MDE)
10/10 Exceptional! (3 reviews)
The house is extremely comfortable and spacious. Luxury amenities that made us feel at home. The pool, jacuzzi and sauna. Graciela the house keeper and Charles our private chef made our stay amazing. It was nice that they had a lunch and dinner menu available for those days we wanted to stay in. Probably one of the best stays in Medellin. The location is just minutes away from Provenza and surroundings. Manuela the host was super attentive, helping us with reservations at restaurants.

Reviewed on Mar 24, 2025

Wellcomm Spa & Hotel

Wellcomm Spa & Hotel

4 out of 5
El Poblado
Save 100% on your flight
Price was $879, price is now $514 per person
$514
per person
Nov 11 - Nov 17
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
9.4/10 Exceptional! (344 reviews)
All was great and very amazing service

Reviewed on Sep 17, 2025

Blues Suites Medellin

Blues Suites Medellin

4 out of 5
El Poblado
Save 100% on your flight
Price was $990, price is now $579 per person
$579
per person
Nov 11 - Nov 17
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
9/10 Wonderful! (906 reviews)
The property is really good the bad thing about this hotel is that you can hear the people on the next room.

Reviewed on Oct 3, 2025

HOTEL NAKAMA

HOTEL NAKAMA

3 out of 5
Laureles
Save 100% on your flight
Price was $863, price is now $513 per person
$513
per person
Dec 21 - Dec 28
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
2/10 (3 reviews)
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Santo Domingo Hotel Deals

Hotel Santo Domingo

Hotel Santo Domingo

3 out of 5
1336 Cra. 16, Santo Domingo, Antioquia
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Hotel Santo Domingo
The Brown, Guatape, Autograph Collection

The Brown, Guatape, Autograph Collection

4 out of 5
El Peñol - Guatape Paraje, Vereda Los Naranjos, Guatapé, Antioquia
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $164 total per night from Oct 20 to Oct 21
$164 total
Oct 20 - Oct 21
9/10 Wonderful! (360 reviews)
"Beautiful views from the room, very clean. The staff absolutely go out of the way to Make You Feel at home. The views are espectacular."

Reviewed on Sep 28, 2025

The Brown, Guatape, Autograph Collection
Hotel Los Recuerdos

Hotel Los Recuerdos

3.5 out of 5
Via Peñol Gatapé Km 19, Guatapé, Antioquia
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $82 total per night from Oct 13 to Oct 14
$82 total
Oct 13 - Oct 14
8/10 Very Good! (562 reviews)
"Beautiful views. Only stayed one night but enjoyed the pools very much."

Reviewed on Sep 30, 2025

Hotel Los Recuerdos
See all 571 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santo Domingo Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Jose Maria Cordova Intl. Airport (MDE)

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Frequently asked questions

How much does a Santo Domingo vacation package cost?
You can grab a vacation package to this destination from $427 on Expedia. But how much your vacation to Santo Domingo costs will depend on the length of stay, hotel choice and season.
What are the cheapest months to go to Santo Domingo?
You can generally find lower rates and greater availability in November, December and January. Explore our cheap Santo Domingo vacation packages and you could score some great off-season discounts.
How many days is enough for Santo Domingo?
The ideal length for your Santo Domingo vacation depends on what you'd like to see and do. Generally, a handful of days to a week will give you time to hit all the leading attractions and discover some hidden gems along the way.
How to find the best Santo Domingo package deals?
Landing a cheap Santo Domingo package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a few filters and see what's available. You can tweak your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to view the most economical Santo Domingo package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Santo Domingo vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking flights and hotels individually. Better still, you can personalize your Santo Domingo escape to match your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Santo Domingo?
If you're considering a spontaneous Santo Domingo getaway, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
How to plan a trip to Santo Domingo?

  1. Choose when to travel: Check your diary and get packing. Your favorite time of year and the type of activities on offer will also help you decide when to escape to Santo Domingo.
  2. Set your budget: Consider costs like flights, food and transportation when working out how much to set aside for your trip to Santo Domingo. Then, pick a property that works with your budget, whether that's an affordable option or a high-end getaway.
  3. Use Expedia's trip planning tool to explore Santo Domingo: Research every aspect of your trip to Santo Domingo with this comprehensive planner. Invite your friends and family to collaborate on a group trip, search for stays or things to do and make bookings.
  4. Decide how long to go away for: Now that you're up to speed on Santo Domingo, you can figure out the right length of your break. Create a draft itinerary and allocate enough time to cover everything you want to do.
  5. Combine your hotel and flights: Epic destination, check. Length of stay, check. Now all that's left is to choose a Santo Domingo vacation package that brings all your bookings together.
  6. Book any activities or day trips: Here's the fun part — locking in everything you want to see and do. Check out some of the exciting things to do in Santo Domingo and book your tickets early to save time (and maybe some cash too!).

Does Expedia offer Book Now, Pay Later Santo Domingo vacation packages?
Your Santo Domingo break is meant to be a relaxing escape from your daily routine, not a source of money-related stress. So to give you that extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there are no hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.