Second Mesa, AZ

Travel Guide

A canyon with a prominent rock formation on the left and the sun setting in the distance.
A deep canyon with layered rock formations and a winding road.
Hopi Cultural Center

Hopi Cultural Center

2 out of 5
Highway 264, Milepost 379 Second Mesa AZ
The price is $136 total per night from Nov 11 to Nov 12
$136 total
per night
Nov 11 - Nov 12
Stay at this motel in Second Mesa. Enjoy free WiFi, free parking, and a conference center. Our guests praise the helpful staff in our reviews.
8.2/10 Very Good! (416 reviews)
"We loved the hospitality of the stuff."

Reviewed on Nov 3, 2026

Hopi Cultural Center
See all properties in Second Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Junipine Resort

Junipine Resort

3.5 out of 5
8351 N Highway 89A Sedona AZ
Stay at this aparthotel in Sedona. Enjoy free WiFi, free parking, and a garden. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9.4/10 Exceptional! (2,575 reviews)
"The cabin was gorgeous and spacious but it wasn’t what I had requested. I originally booked a 1 room cabin but got a way bigger space which was nice but it was just way too big for just me. Additionally due to the flash flood, we lost power and there was no communication from management regarding ..."

Reviewed on Nov 9, 2026

Junipine Resort
Scottsdale Camelback Resort

Scottsdale Camelback Resort

4 out of 5
6302 E Camelback Rd Scottsdale AZ
Book a stay at this spa aparthotel in Scottsdale. Enjoy free parking, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,673 reviews)
"I enjoyed every aspect of the villas, the room, location and staff! The property has aged beautifully and it’s still a favorite place to stay."

Reviewed on Nov 10, 2026

Scottsdale Camelback Resort
Placemakr Downtown Phoenix

Placemakr Downtown Phoenix

4 out of 5
311 N 1st Ave Phoenix AZ
Stay at this aparthotel in Phoenix. Enjoy free WiFi, a rooftop terrace, and a 24-hour fitness center. Popular attractions Mortgage Matchup Center and Chase Field ...
Placemakr Downtown Phoenix
See all 37,243 properties in Arizona
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

When is the best time to visit Second Mesa?
The best time to visit Second Mesa is from April through June, when travelers can enjoy pleasant temperatures and comfortable conditions. For fewer crowds and better value, the quieter months of November through February are a good option, offering cooler weather for exploring the area.
Can I book a refundable hotel in Second Mesa?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Second Mesa by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Second Mesa with Expedia?
Expedia makes it easier to plan your Second Mesa trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Second Mesa?
The best choice depends on your travel style. Hotels in Second Mesa can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Second Mesa trip on Expedia?
Once you've booked your Second Mesa trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Second Mesa trip?
Expedia offers customer support before, during, and after your Second Mesa trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Second Mesa?
If it's your first trip to Second Mesa, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Second Mesa hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Second Mesa hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

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