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Due to coronavirus (COVID-19) travel advisories, some destinations may be unavailable for certain dates. Find out more.
Due to coronavirus (COVID-19) travel advisories, some destinations may be unavailable for certain dates. Find out more.

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Free cancellation on most hotels. Because flexibility matters.


South America Vacation: Coronavirus Information

Most South America hotels offer free cancellation. Consider booking refundable hotels rather than non-refundable ones. Just look for the ‘free cancellation’ message during your hotel search. Prices can vary, but right now we believe that flexibility matters.

For more information about the impact of COVID-19 on your South America trip, please visit our Coronavirus Information page (opens in new window).

South America Vacations

Vacationing is good for the soul. It lets you rest, relax, recharge, and refresh, so you’re ready to take on new endeavors when you return home. When it’s time to let loose and embark on a group adventure or unwind and rejuvenate on a solo sojourn, turn to Expedia for major discounts on South America vacation packages. It’s easy to book the getaway of your dreams when you search through our selection of South America vacations. Our goal? To create the perfect trip for you by providing the largest selection of vacation packages. Confidently book your getaway thanks to our trustworthy recommendations and verified consumer reviews from travelers just like you. Personalize your South America package with our myriad of hotel rooms and flight tickets, which help to create a vacation specifically for you. Simply sort through our selection and pick and choose the elements that best suit your preferences and price range. Because we offer the best rates, you can book your travel reservations knowing you won’t find lower prices elsewhere. These discounts are so great, you’ll feel like you gained the title of the ultimate bargain hunter with our South America vacation package deals. Whether you’re looking to book multiple flights, stay at the fanciest hotel, or explore the hottest local attractions, you’ll find discounted travel arrangements within your budget right here. You shouldn’t have a care in the world when you go on vacation, so our discounts allow you to rest easy without giving your bank account a second thought. Save money on your vacation today and revel in your much-deserved getaway tomorrow.

Best Lodging Options Near South America

See all 69,996 Properties in South America
Rochester Classic $50
Reviewed on Nov 3, 2019
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Rochester Classic

Rochester Classic

Esmeralda 542, Buenos Aires, Capital Federal
     
    3.7 of 5
    3.5 out of 5.0 Stars

    The hotel was neat but not as well kept as it could have been. There were some broken items in the room, particularly the bathroom. It all worked but it was just not top form.

    Regal Pacific Buenos Aires $120
    Reviewed on Mar 1, 2020
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    Regal Pacific Buenos Aires

    Regal Pacific Buenos Aires

    25 De Mayo, 764, Buenos Aires, Capital Federal
       
      4.4 of 5
      4.5 out of 5.0 Stars

      Very friendly and help guests with smiles.

      Almacruz Hotel y Centro de Convenciones (Ex Galerías)
      Reviewed on Mar 20, 2020
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      Almacruz Hotel y Centro de Convenciones (Ex Galerías)

      Almacruz Hotel y Centro de Convenciones (Ex Galerías)

      San Antonio 65, Santiago, Region Metropolitana
         
        4.0 of 5
        4.0 out of 5.0 Stars

        Nice hotel, very centrally located in a pedestrian friendly part of the old city.

        Argentina Tango Hotel $28
        Reviewed on Nov 5, 2019
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        Argentina Tango Hotel

        Argentina Tango Hotel

        Suipacha 545, Buenos Aires, Capital Federal
           
          2.7 of 5
          3.0 out of 5.0 Stars

          Breakfast was not up to scratch as there was no protein component. Lifts need upgrading and are noisy

          Mercure Santiago Centro $64
          Reviewed on Oct 27, 2019
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          Mercure Santiago Centro

          Mercure Santiago Centro

          Av. Libertador Bernardo O Higgins, 632, Centro, Santiago, Region Metropolitana
             
            4.1 of 5
            3.5 out of 5.0 Stars

            ✔️Amazing caring staff during the October Riots very close to the Hotel. Truly concerned about our safety and wellbeing. The procedure of keeping us safe in the basement during the scary fighting and looting and teargassing worked perfectly. I was evacuated by the hotel management, all the guests ...

            Globales Republica $47
            Reviewed on Feb 5, 2020
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            Globales Republica

            Globales Republica

            Cerrito 370, Buenos Aires, Capital Federal
               
              3.7 of 5
              3.5 out of 5.0 Stars

              Was able to check in early after leaving the cruise ship.

              Departamentos Amoblados Torre Tagle
              Reviewed on Jan 23, 2020
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              Departamentos Amoblados Torre Tagle

              Departamentos Amoblados Torre Tagle

              Monjitas 744, Santiago, Region Metropolitana
                 
                3.8 of 5
                3.5 out of 5.0 Stars

                Excellent value. We had booked two bedrooms apart, and it was very spacious. Good facilities in the building with coin laundry and rooftop swimming pool. We enjoyed our relaxing stay.

                Hilton Buenos Aires $145
                Reviewed on Mar 17, 2020
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                Hilton Buenos Aires

                Hilton Buenos Aires

                Av Macacha Guemes 351, Buenos Aires, Capital Federal
                   
                  4.4 of 5
                  4.5 out of 5.0 Stars

                  El hotel espectacular como siempre, en este caso había un problema general con el aire acondicionado pero solventaron la situación, muy amable el staff

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