Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.
Enjoy maximum flexibility with penalty-free cancellation on most car rentals.
Expedia.com makes it easy for you to book your next South America car rental. We work with the best car rental companies in South America, bringing you discount car rental rates and a wide variety of car rental classes including economy, compact, midsize, full-size, convertible, van, luxury, full size and SUV rentals. Our partner car rental companies in South America offer different pick-up and drop-off options. If you are ready to book your South America car rental, follow the links on this page to view more information and details on your next short or long term car rental.
Expedia.com offers a wide selection of rental cars in South America to meet nearly every need. If you need any special equipment, like a child seat or ski rack, let us know and we will forward your request on to the rental car company. And what's more, when you choose to rent a car from one of our South America airport car rental partners you'll be dealing with a rental car company that has made a special commitment to provide Expedia customers with great customer service, a wide choice of top quality cars, and competitive total pricing.
Find the best place to get your South America airport rental cars by searching tons of pickup locations with Expedia.com