Title: Top Independent in Southeast Iowa - Expedia.com [Southeast Iowa Travel Guide](https://expedia.com/Southeast-Iowa.dx6234151)[Hotels in Southeast Iowa](https://expedia.com/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels)[Vacation Rentals in Southeast Iowa](https://expedia.com/Southeast-Iowa-Vacation-Rentals.d6234151.Travel-Guide-VacationRentals)[Flights to Southeast Iowa](https://expedia.com/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights)[Car Rentals in Southeast Iowa](https://expedia.com/Car-Rentals-In-Southeast-Iowa.d6234151.Car-Rental-Guide)[Southeast Iowa Vacation Packages](https://expedia.com/Southeast-Iowa.d6234151.Destination-Travel-Guides) ![Found this bridge while exploring. It used to be a railroad bridge, transformed to a buggy bridge, and not after restoration is a walking path bridge. It stretches over a hundred feet and while walking you can still see the old railroad and boards for the buggy. ](https://images.trvl-media.com/place/6052570/9ddd26bd-82be-41a2-94d7-8f1f7c77e19f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michael Schuier ![](https://images.trvl-media.com/place/6052570/9ddd26bd-82be-41a2-94d7-8f1f7c77e19f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 7 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6234151&startDate=2026-03-07&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 8 - Mar 9](https://www.expedia.com/Hotel-Search?regionId=6234151&startDate=2026-03-08&endDate=2026-03-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6234151&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6234151&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Iowa-Hotels-Independent.0-0-d6234151--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Iowa-Hotels-Independent.0-0-d6234151--bIndependent.Travel-Guide-Filter-Hotels) ## Top Southeast Iowa Hotel Reviews ![AmericInn by Wyndham Mount Pleasant](https://images.trvl-media.com/lodging/1000000/130000/124500/124480/21fbbb57_y.jpg) ### AmericInn by Wyndham Mount Pleasant 10/10 Excellent "clean room. Friendly staff." [](https://expedia.com/Burlington-Hotels-AmericInn-By-Wyndham-Mount-Pleasant.h124480.Hotel-Information) ![Best Western Mt. Pleasant Inn](https://images.trvl-media.com/lodging/1000000/60000/50100/50061/f895586a_y.jpg) ### Best Western Mt. Pleasant Inn 10/10 Excellent "Great selection. I was pleasantly surprised. " [](https://expedia.com/Burlington-Hotels-Best-Western-Mt-Pleasant-Inn.h50061.Hotel-Information) ![Quality Inn & Suites Keokuk North](https://images.trvl-media.com/lodging/1000000/50000/42600/42551/5f87e5cd_y.jpg) ### Quality Inn & Suites Keokuk North 8/10 Good "Hot tub closed" [](https://expedia.com/Burlington-Hotels-Quality-Inn-Suites-Keokuk-North.h42551.Hotel-Information) ![Comfort Suites Burlington](https://images.trvl-media.com/lodging/2000000/1190000/1183600/1183571/49287866_y.jpg) ### Comfort Suites Burlington 8/10 Good "The clean room" [](https://expedia.com/Burlington-Hotels-Comfort-Suites-Burlington.h1183571.Hotel-Information) ![Hampton Inn Keokuk](https://images.trvl-media.com/lodging/2000000/1480000/1478200/1478193/b1b8714b_y.jpg) ### Hampton Inn Keokuk 8/10 Good "The room was spacious and comfortable. The staff was friendly and welcoming and the breakfast was terrific. Especially notable is Sara who is the "breakfast lady" - such a warm, friendly, caring person - a true joy." [](https://expedia.com/Burlington-Hotels-Hampton-Inn-Keokuk.h1478193.Hotel-Information) ![Cobblestone Inn & Suites - Fort Madison](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/7c968180_y.jpg) ### Cobblestone Inn & Suites - Fort Madison 10/10 Excellent "good breakfast and nice clean rooms" [](https://expedia.com/Burlington-Hotels-Cobblestone-Inn-Suites-Fort-Madison.h9534717.Hotel-Information) ![AmericInn by Wyndham West Burlington](https://images.trvl-media.com/lodging/1000000/560000/550600/550579/dc2defbe_y.jpg) ### AmericInn by Wyndham West Burlington 10/10 Excellent "The staff is amazing, so very helpful, and the cleaning crew is amazing and friendly! Thank you for a pleasant stay!" [](https://expedia.com/Burlington-Hotels-AmericInn-By-Wyndham-West-Burlington.h550579.Hotel-Information) ![Holiday Inn Express Hotel & Suites Burlington by IHG](https://images.trvl-media.com/lodging/1000000/30000/23100/23041/12350ef3_y.jpg) ### Holiday Inn Express Hotel & Suites Burlington by IHG 8/10 Good "Room was clean and staff was excellent. Noisy people in the halls and parking lot early in the morning" [](https://expedia.com/Burlington-Hotels-Holiday-Inn-Express-Hotel-Suites-Burlington.h23041.Hotel-Information) ![The Catfish Bend Inn & Spa](https://images.trvl-media.com/lodging/40000000/39220000/39213700/39213685/274a5133_y.jpg) ### The Catfish Bend Inn & Spa 10/10 Excellent "EVERYTHING WAS GREAT!" [](https://expedia.com/Burlington-Hotels-The-Catfish-Bend-Inn-Spa.h39213685.Hotel-Information)