Search Vacation Homes in Southern Illinois

Start date: Check-in selected.
To Date
End date: Check-out

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Next weekend
Nov 14 - Nov 16
In two weeks
Nov 21 - Nov 23
In one month
Dec 5 - Dec 7
In two months
Jan 2 - Jan 4

Vacation Homes in Southern Illinois

Interior
Vintage Charmer on Main Street

Vintage Charmer on Main Street

Greenup
10.0 out of 10, Exceptional, (55)
"Perfect place to stay if in that area. First time booking a place and am very pleased with this one. I would book it again. Thanks for the great stay."
United States
Deb A.
$131 nightly
The price is $138
Nov 17 - Nov 18
Total with taxes and fees
Vintage Charmer on Main Street
Exterior
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping

The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping

Harrisburg
9.8 out of 10, Exceptional, (18)
"We loved our stay here! The house was charming, clean, and private, exactly what we needed for a relaxing getaway. It had a welcoming feel and gave us the perfect balance of comfort and peace. Highly recommend!"
United States
Autumn
$160 nightly
The price is $170
Nov 15 - Nov 16
Total with taxes and fees
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
Interior
Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAY

Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAY

Equality
9.4 out of 10, Exceptional, (16)
"Great place to stay!"
United States
Alicia J.
$209 nightly
The price is $222
Nov 15 - Nov 16
Total with taxes and fees
Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAY
Fridge, microwave, oven, stovetop
Brickway Retreat

Brickway Retreat

Mattoon
9.8 out of 10, Exceptional, (38)
"This property was very clean, super cute and very comfortable. The character that was maintained in the home, while being updated was amazing! I will definitely stay here again! "
United States
Amanda J.
$170 nightly
The price is $180
Nov 19 - Nov 20
Total with taxes and fees
Brickway Retreat
Exterior
Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64

Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64

Ina
9.6 out of 10, Exceptional, (19)
"It was a very nice stay for our family. Thank you!"
United States
Daniel T.
$332 nightly
The price is $352
Dec 1 - Dec 2
Total with taxes and fees
Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64
Exterior
Countryside Private Guest Room

Countryside Private Guest Room

Freeburg
10.0 out of 10, Exceptional, (17)
"Owners were awesome and it was my first time staying in a B&B . I will never stay in another hotel when visiting StLouis . I was very impressed with the hospitality and location ."
United States
David B.
$88 nightly
The price is $93
Nov 21 - Nov 22
Total with taxes and fees
Countryside Private Guest Room
1 bedroom, WiFi, bed sheets
Charming 1-bedroom house in terrific Harrisburg with AC, WiFi

Charming 1-bedroom house in terrific Harrisburg with AC, WiFi

Harrisburg
9.8 out of 10, Exceptional, (9)
"Clean, cute decor great yard! Good location "
United States
Cheryl C.
$171 nightly
The price is $181
Nov 13 - Nov 14
Total with taxes and fees
Charming 1-bedroom house in terrific Harrisburg with AC, WiFi
Exterior
Millstone Cottage

Millstone Cottage

Simpson
10.0 out of 10, Exceptional, (25)
"It was a great one night stay before dropping my kids off at camp. Would definitely stay here again."
United States
Susan H.
$206 nightly
The price is $218
Nov 11 - Nov 12
Total with taxes and fees
Millstone Cottage
Terrace/patio
Handicap Accessible Studio w/ Full Kitchen on the River

Handicap Accessible Studio w/ Full Kitchen on the River

2.0 star property
Stone Church Precinct
8.8 out of 10, Excellent, (5)
"Lovely property, and cabin was comfortable and clean. The hosts were so accommodating and nice"
United States
Finlay S.
$144 nightly
The price is $155
Nov 12 - Nov 13
Total with taxes and fees
Handicap Accessible Studio w/ Full Kitchen on the River
Outdoor dining
Beautiful location in the secluded woods

Beautiful location in the secluded woods

Pomona
10.0 out of 10, Exceptional, (56)
"The house was lovely, the location beautiful and quiet. The host was very attentive and made sure our stay was perfect "
United States
Dianna S.
$170 nightly
The price is $180
Nov 30 - Dec 1
Total with taxes and fees
Beautiful location in the secluded woods
Smart TV
Park View Place 4 Blocks From the World's Biggest

Park View Place 4 Blocks From the World's Biggest

Casey
10.0 out of 10, Exceptional, (37)
"Had a Family Reunion was great old Friends stopped in also a nd ofcourse Big rhings "
United States
Rita L.
$203 nightly
The price is $215
Nov 16 - Nov 17
Total with taxes and fees
Park View Place 4 Blocks From the World's Biggest
Outdoor dining
Cozy Corner Mascoutah

Cozy Corner Mascoutah

Mascoutah
9.6 out of 10, Exceptional, (72)
"I was looking for a quiet, relaxing place to stay while visiting family in a nearby town. This was just what I wanted. Would definitely stay again next time I’m in the area. "
United States
Ann G.
$185 nightly
The price is $196
Nov 11 - Nov 12
Total with taxes and fees
Cozy Corner Mascoutah
Fridge, microwave, oven, stovetop
Pigs Ina Blanket - Minutes from Rend Lake and I-64/I-57

Pigs Ina Blanket - Minutes from Rend Lake and I-64/I-57

Ina
9.0 out of 10, Wonderful, (35)
"Great Place. Will stay again."
United States
Katja B.
$294 nightly
The price is $312
Nov 16 - Nov 17
Total with taxes and fees
Pigs Ina Blanket - Minutes from Rend Lake and I-64/I-57
Property grounds
Peter Ray House

Peter Ray House

Maeystown
10.0 out of 10, Exceptional, (70)
"The house was wonderful, the town was delightful, and the people were very friendly! We can’t wait for our next trip!"
United States
Deborah
$212 nightly
The price is $225
Nov 13 - Nov 14
Total with taxes and fees
Peter Ray House
Property grounds
Standard Suite - Bungalow overlooking the River

Standard Suite - Bungalow overlooking the River

Golconda
9.6 out of 10, Exceptional, (25)
"Very much enjoyed the place. It had lovely surroundings."
United States
Tevi R.
$144 nightly
The price is $155
Nov 12 - Nov 13
Total with taxes and fees
Standard Suite - Bungalow overlooking the River
Children's area
Comfy Clean & Cute

Comfy Clean & Cute

Marion
9.2 out of 10, Wonderful, (27)
"Just as advertised clean and comfy. Host was very helpful. We usually stay in hotels but this was a much better experience. "
United States
Tim W.
$186 nightly
The price is $223
Nov 16 - Nov 17
Total with taxes and fees
Comfy Clean & Cute
Fridge, microwave, oven, stovetop
Du Quoin Fairgrounds

Du Quoin Fairgrounds

Du Quoin
9.6 out of 10, Exceptional, (14)
"Great communication. Wonderful place to stay."
United States
Tammy
$167 nightly
The price is $176
Nov 15 - Nov 16
Total with taxes and fees
Du Quoin Fairgrounds
Interior
New listing! Private 3 bedroom 2 bath home with BEAUTIFUL sunroom!

New listing! Private 3 bedroom 2 bath home with BEAUTIFUL sunroom!

Olney
10.0 out of 10, Exceptional, (52)
"This was a great house to stay with a family!"
United States
Anonymous traveler
$158 nightly
The price is $167
Nov 16 - Nov 17
Total with taxes and fees
New listing! Private 3 bedroom 2 bath home with BEAUTIFUL sunroom!
Interior
Secluded treehouse with indoor fireplace

Secluded treehouse with indoor fireplace

Makanda
10.0 out of 10, Exceptional, (16)
"Had a great stay. The treehouse was unique and a great get away spot while enjoying the local winery’s. We’ll be back for more fun this upcoming fall. "
United States
Nathaniel M.
$190 nightly
The price is $201
Nov 19 - Nov 20
Total with taxes and fees
Secluded treehouse with indoor fireplace
Interior
Charming 2-bedroom barn-style home nestled on 6 acres in delightful Vienna

Charming 2-bedroom barn-style home nestled on 6 acres in delightful Vienna

Vienna
$158 nightly
The price is $168
Nov 12 - Nov 13
Total with taxes and fees
Charming 2-bedroom barn-style home nestled on 6 acres in delightful Vienna
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southern Illinois Hotel Reviews

Country Inn & Suites by Radisson, Fairview Heights, IL

Country Inn & Suites by Radisson, Fairview Heights, IL

10/10 Excellent
"Good for one night viait while traveling "
GRAHAM 1-night trip
Posted 1 day ago
Country Inn & Suites by Radisson, Fairview Heights, IL

Find out more about Southern Illinois

Southern Illinois Vacation Homes information

Number of reviews
Accommodation
 Vacation Homes
Lowest Price
Highest Price

Explore a world of travel with Expedia