A calm lake surrounded by trees and vegetation.
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Southwest Illinois Vacations from $548

Book a Hotel + Flight or Car together to unlock savings

Your Southwest Illinois Vacation

When it's time for your next epic adventure, our Southwest Illinois vacation packages are the answer. Culture and history are among the many things that make this destination such a special place. Begin your trip to Southwest Illinois with some time exploring O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Marion is another city that lures travelers from all over. Lake of Egypt and Crab Orchard National Wildlife Refuge are two of the top places to see in this destination. From the moment you book your Southwest Illinois vacation to the second you come back home, Expedia will be with you each step of the way.

The Latest Southwest Illinois Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 28 - Jan 31

    Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West + Flight

    Riverport
    3 nights
    3.0 star property
    7.8/10 - Good (1,006 reviews)
    Roundtrip • New York (EWR) - St. Louis (STL)
    EWR - STL • Nonstop STL - EWR • Nonstop
    $639
    $548
    per traveler
    found 1 day ago
    Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
  • Jan 28 - Jan 31

    The Wildwood Hotel + Flight

    Wildwood
    3 nights
    3.5 star property
    9.2/10 - Wonderful (1,682 reviews)
    "Everything was good. Seemed that the property was not full but we were forced into a suite."
    Reviewed November 7, 2026
    Roundtrip • New York (EWR) - St. Louis (STL)
    EWR - STL • Nonstop STL - EWR • Nonstop
    $859
    $584
    per traveler
    found 1 day ago
    The Wildwood Hotel
  • Jan 28 - Jan 31

    Remodeled and Inviting Free EV + Flight

    Fenton
    3 nights
    2.0 star property
    9.4/10 - Exceptional (3 reviews)
    "We had a great time with my family ❤️ thank you"
    Reviewed October 12, 2026
    Roundtrip • New York (EWR) - St. Louis (STL)
    EWR - STL • Nonstop STL - EWR • Nonstop
    $922
    $678
    per traveler
    found 1 day ago
    Remodeled and Inviting Free EV
  • Jan 28 - Jan 31

    The Cheshire + Flight

    Richmond Heights
    3 nights
    4.0 star property
    8.8/10 - Excellent (1,005 reviews)
    "Great service!! Lovely breakfast options"
    Reviewed November 9, 2026
    Roundtrip • New York (EWR) - St. Louis (STL)
    EWR - STL • Nonstop STL - EWR • Nonstop
    $820
    $679
    per traveler
    found 1 day ago
    The Cheshire
  • Jan 28 - Jan 31

    Ameristar Casino Resort and Spa + Flight

    St. Charles
    3 nights
    4.5 star property
    8.6/10 - Excellent (1,094 reviews)
    "We were here for a wedding. Our room was very nice but my son’s bathroom was disgusting and not clean, they had to switch rooms and the only compensation they gave them was a food voucher. Not acceptable with blood and vomit not cleaned from previous guest. We expected more for this caliber of hotel."
    Reviewed November 8, 2026
    Roundtrip • New York (EWR) - St. Louis (STL)
    EWR - STL • Nonstop STL - EWR • Nonstop
    $860
    $721
    per traveler
    found 1 day ago
    Ameristar Casino Resort and Spa

Discover the most popular places to visit in Southwest Illinois

Southwest Illinois Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

What's included in a Southwest Illinois vacation package?

A Southwest Illinois vacation package in O'Fallon lets you combine flights, hotel stays, and rental cars. Most hotels in O'Fallon offer free breakfast, and some also provide airport shuttle service to St. Louis Lambert International Airport (STL). Exactly what's included will vary by hotel and package, so it's worth reviewing the details before you confirm your booking.

How can I save money on a Southwest Illinois vacation package?

When you bundle, you can save up to 30%*. To save money on a Southwest Illinois package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.

Which destinations should I consider for a Southwest Illinois vacation?

When planning a Southwest Illinois vacation, consider these destinations as your base, each offering a distinct travel style:

  • Marion: A top choice for romantic getaways and outdoor adventures, known for its scenic views and a good selection of lodging.
  • Carbondale: Ideal for travelers seeking romantic trips and active outdoor experiences, with many options for adventure activities.
  • O'Fallon: Best suited for families and those interested in urban attractions, also offering outdoor activities and eco-friendly travel options.
  • Edwardsville: A great base for family-friendly attractions and romantic escapes, combining outdoor activities with scenic surroundings.

Is Southwest Illinois better suited for a beach vacation or a cultural trip?

Southwest Illinois is primarily an outdoor and nature destination, known for its scenic views and adventure activities. Travelers can enjoy a wide range of outdoor pursuits, from exploring the waters of Lake of Egypt in Marion to hiking the unique geological formations at Giant City State Park near Carbondale.


The region does offer cultural and historical experiences. Visitors can delve into ancient history at Cahokia Mounds State Historic Site near O'Fallon or enjoy local arts and events at the Marion Cultural and Civic Center. Your Southwest Illinois vacation can be customized around these diverse activities.

Which airport should I use for a Southwest Illinois vacation?

For a Southwest Illinois vacation, St. Louis Lambert International Airport (STL) in St. Louis, Missouri, serves as the primary gateway. Another convenient option is Evansville Regional Airport (EVV) in Evansville, Indiana. Both airports serve the wider Southwest Illinois region, with onward travel to your specific destination.

What are the top things to do in Southwest Illinois?

A Southwest Illinois vacation is best explored from a base like Marion, which offers a variety of outdoor activities and scenic views:


Browse and book things to do in Southwest Illinois on Expedia.

Can I change or cancel my Southwest Illinois vacation package if my plans change?

Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.

Do One Key members get extra savings when booking Southwest Illinois vacation packages?

Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.

Does Expedia offer Book Now, Pay Later Southwest Illinois vacation packages?

Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Southwest Illinois vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.

How do I find last-minute vacation packages to Southwest Illinois?

To find last-minute vacation packages to Southwest Illinois, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.

How does free cancellation work on Southwest Illinois vacation packages?

Free cancellation on a Southwest Illinois vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.

Is it cheaper to book a Southwest Illinois vacation as a package or separately?

An Expedia vacation package could land you great savings when compared to arranging flights and hotels separately. Better still, you can tailor your Southwest Illinois getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.

Why should I book my Southwest Illinois vacation package with Expedia?

Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.